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The map label for this gene is ykoH [H]

Identifier: 55981472

GI number: 55981472

Start: 1431615

End: 1433021

Strand: Direct

Name: ykoH [H]

Synonym: TTHA1503

Alternate gene names: 55981472

Gene position: 1431615-1433021 (Clockwise)

Preceding gene: 55981471

Following gene: 55981479

Centisome position: 77.4

GC content: 70.58

Gene sequence:

>1407_bases
ATGACCCTTAGGACCCGGATCACCCTCCTCACGGCGGGGCTCCTCCTCGTGGCCTTTTTGGTCCTCGGCTTCGCCCTGGA
GGGGCTCCTTCGGAACTTCCTCTACGGGAGCCTGCGCACCGACCTGAAGGAGGCGGCCAACCAGGTGGTGCGCCTCCTCA
ACCTGGGGGGGCAGGCCCTCCTCGAGGCCGGCCTCCCCCCGAGCCTCTACGCCGAGGTCCAGCTCCTCCCCGAGGAGGAC
CCGGCCCTCCTCGCCCGGGAGGGCGGGATCAGCCTGCAGAAAAGCCCCGCCCTGGGAAGCCAGCGCCTCCTCCTCCAGGA
GGAGGCCTACCGGGAGCTCCTCAAGCGGGGAGAGGTGTGGGCCTACGCGGAGCTCCCCCGTGAGGGCCACCCCCTGCGGC
TTCTCGTCTACGCCCGGAAGGTGGAGGTCAACCTCTCGGGCTCGGTGTGGAAGGGCGCCCTCCTCGTGGGCCGGCCCACG
GAGGACCTGGAGGCCACCCTAAGCCAGTTCGCCCGCATCTACGCGGGCACGGCCCTCTTCGTCCTCCTCCTCTCCCTCTT
CCTCGCCCGCAGCCTCGTGGCCCGGGCCCTGGAGCCCTTGGAGTGGGCGGCGCGCAAGGCCGAGGCCATGAGCGCCCGCC
CCGAGCCCTTACCGGAGCCGGAAACCCGGGACGAGGTGGCCGCCCTGGTCAAGGCCCTGAACGGGATGCTCACCCGCCTG
CAGGAGGCCTTTGAGGCCCAGACCCGCTTCCTCCAGGACGCCTCCCACGAGCTCAGGACCCCCATCACCGCCATCCTGGG
GCACGTGGGCTACCTGCTCCGGCGCACCCCCCTCACCGAGGCCCAGCGGGAGAGCCTCGAGGTGGTGAAGCGGGAGGCGG
AGCGCATGGGTAAGCTCGTCTCCGACCTCCTGGACCTCTCGCAAAGCGGCGCCTGGAGGATCCGCCCTGTGCCTGTGCGG
GTCTTGGACCTCCTGGAAGAGGTGCGGGAGGAGTTCGCCAAAAGCTTTGACGGGGAGATCCTGGTGGAGGCCCCCGAGGA
CCTCTACGTCCTGGGGGACCCCGACCGGCTCCACCAGGTCATGGCCAACCTGGTCTCCAACGCCCTCAAGGCGGGGGCCC
GGCACGTGTGGCTTAGGGCCTTTGACCTAGGGGACAAGGCGGTGGTCCGGGTGGAGGACGACGGGGAGGGGATCCCCGAG
GAGCACCTCCCCCACCTCTTTGAGCGCTTCTACCGGGTGGACAAGGCCCGGGACCGGGAACGGGGCGGGTCGGGCCTCGG
CCTCGCCATCGTGAAGGCCATCCTCGAGGCCCACGGGGGGGAGGTCTGGGTGGAGAGCCAGGTGGGCAAGGGGACGGCCT
TCAGCTTTTCCCTTCCCGCAAGCGGGCCACCGCCTCCTCCACGCTGA

Upstream 100 bases:

>100_bases
CAAGAAGCTGGAGGCGGGGGGGGAGCGCCGCCTCATCCACACGGTGCGGGGCGTGGGGTACGTCCTCAGGGAGGACTGAG
CCCAAGCCTAGCCTCCCGGC

Downstream 100 bases:

>100_bases
TCTCCCCCCGCCTTAGGGCCTCCAGGACCTCGAGGCGGTCCTTCCCCTCGTCCTCCTCGTACCCCAGGGCCTTCAGGAGG
GCGTCCAGCCGGGCCCGCAC

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 467

Protein sequence:

>468_residues
MTLRTRITLLTAGLLLVAFLVLGFALEGLLRNFLYGSLRTDLKEAANQVVRLLNLGGQALLEAGLPPSLYAEVQLLPEED
PALLAREGGISLQKSPALGSQRLLLQEEAYRELLKRGEVWAYAELPREGHPLRLLVYARKVEVNLSGSVWKGALLVGRPT
EDLEATLSQFARIYAGTALFVLLLSLFLARSLVARALEPLEWAARKAEAMSARPEPLPEPETRDEVAALVKALNGMLTRL
QEAFEAQTRFLQDASHELRTPITAILGHVGYLLRRTPLTEAQRESLEVVKREAERMGKLVSDLLDLSQSGAWRIRPVPVR
VLDLLEEVREEFAKSFDGEILVEAPEDLYVLGDPDRLHQVMANLVSNALKAGARHVWLRAFDLGDKAVVRVEDDGEGIPE
EHLPHLFERFYRVDKARDRERGGSGLGLAIVKAILEAHGGEVWVESQVGKGTAFSFSLPASGPPPPPR

Sequences:

>Translated_468_residues
MTLRTRITLLTAGLLLVAFLVLGFALEGLLRNFLYGSLRTDLKEAANQVVRLLNLGGQALLEAGLPPSLYAEVQLLPEED
PALLAREGGISLQKSPALGSQRLLLQEEAYRELLKRGEVWAYAELPREGHPLRLLVYARKVEVNLSGSVWKGALLVGRPT
EDLEATLSQFARIYAGTALFVLLLSLFLARSLVARALEPLEWAARKAEAMSARPEPLPEPETRDEVAALVKALNGMLTRL
QEAFEAQTRFLQDASHELRTPITAILGHVGYLLRRTPLTEAQRESLEVVKREAERMGKLVSDLLDLSQSGAWRIRPVPVR
VLDLLEEVREEFAKSFDGEILVEAPEDLYVLGDPDRLHQVMANLVSNALKAGARHVWLRAFDLGDKAVVRVEDDGEGIPE
EHLPHLFERFYRVDKARDRERGGSGLGLAIVKAILEAHGGEVWVESQVGKGTAFSFSLPASGPPPPPR
>Mature_467_residues
TLRTRITLLTAGLLLVAFLVLGFALEGLLRNFLYGSLRTDLKEAANQVVRLLNLGGQALLEAGLPPSLYAEVQLLPEEDP
ALLAREGGISLQKSPALGSQRLLLQEEAYRELLKRGEVWAYAELPREGHPLRLLVYARKVEVNLSGSVWKGALLVGRPTE
DLEATLSQFARIYAGTALFVLLLSLFLARSLVARALEPLEWAARKAEAMSARPEPLPEPETRDEVAALVKALNGMLTRLQ
EAFEAQTRFLQDASHELRTPITAILGHVGYLLRRTPLTEAQRESLEVVKREAERMGKLVSDLLDLSQSGAWRIRPVPVRV
LDLLEEVREEFAKSFDGEILVEAPEDLYVLGDPDRLHQVMANLVSNALKAGARHVWLRAFDLGDKAVVRVEDDGEGIPEE
HLPHLFERFYRVDKARDRERGGSGLGLAIVKAILEAHGGEVWVESQVGKGTAFSFSLPASGPPPPPR

Specific function: Probable member of the two-component regulatory system ykoH/ykoG. Potentially phosphorylates ykoG [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786783, Length=417, Percent_Identity=30.4556354916067, Blast_Score=141, Evalue=7e-35,
Organism=Escherichia coli, GI1786600, Length=235, Percent_Identity=38.2978723404255, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1789149, Length=235, Percent_Identity=33.1914893617021, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1788393, Length=248, Percent_Identity=32.6612903225806, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1790346, Length=231, Percent_Identity=33.7662337662338, Blast_Score=111, Evalue=9e-26,
Organism=Escherichia coli, GI145693157, Length=257, Percent_Identity=29.9610894941634, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI87081816, Length=267, Percent_Identity=32.2097378277154, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1788713, Length=253, Percent_Identity=31.6205533596838, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1790436, Length=219, Percent_Identity=32.8767123287671, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI48994928, Length=238, Percent_Identity=30.672268907563, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1790551, Length=288, Percent_Identity=29.8611111111111, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1789808, Length=455, Percent_Identity=27.4725274725275, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1787894, Length=236, Percent_Identity=30.9322033898305, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788279, Length=304, Percent_Identity=26.9736842105263, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI87082128, Length=223, Percent_Identity=28.6995515695067, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1788549, Length=223, Percent_Identity=29.1479820627803, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1787374, Length=276, Percent_Identity=27.1739130434783, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790861, Length=335, Percent_Identity=26.2686567164179, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1786912, Length=217, Percent_Identity=28.110599078341, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1789403, Length=278, Percent_Identity=29.4964028776978, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 51709; Mature: 51578

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLRTRITLLTAGLLLVAFLVLGFALEGLLRNFLYGSLRTDLKEAANQVVRLLNLGGQAL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
LEAGLPPSLYAEVQLLPEEDPALLAREGGISLQKSPALGSQRLLLQEEAYRELLKRGEVW
HHCCCCCCHHHHEEECCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEE
AYAELPREGHPLRLLVYARKVEVNLSGSVWKGALLVGRPTEDLEATLSQFARIYAGTALF
EEECCCCCCCCEEEEEEEEEEEEEECCCHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHH
VLLLSLFLARSLVARALEPLEWAARKAEAMSARPEPLPEPETRDEVAALVKALNGMLTRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
QEAFEAQTRFLQDASHELRTPITAILGHVGYLLRRTPLTEAQRESLEVVKREAERMGKLV
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
SDLLDLSQSGAWRIRPVPVRVLDLLEEVREEFAKSFDGEILVEAPEDLYVLGDPDRLHQV
HHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEECCHHHHHHH
MANLVSNALKAGARHVWLRAFDLGDKAVVRVEDDGEGIPEEHLPHLFERFYRVDKARDRE
HHHHHHHHHHHCCCEEEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHH
RGGSGLGLAIVKAILEAHGGEVWVESQVGKGTAFSFSLPASGPPPPPR
CCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEECCCCCCCCCCC
>Mature Secondary Structure 
TLRTRITLLTAGLLLVAFLVLGFALEGLLRNFLYGSLRTDLKEAANQVVRLLNLGGQAL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
LEAGLPPSLYAEVQLLPEEDPALLAREGGISLQKSPALGSQRLLLQEEAYRELLKRGEVW
HHCCCCCCHHHHEEECCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEE
AYAELPREGHPLRLLVYARKVEVNLSGSVWKGALLVGRPTEDLEATLSQFARIYAGTALF
EEECCCCCCCCEEEEEEEEEEEEEECCCHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHH
VLLLSLFLARSLVARALEPLEWAARKAEAMSARPEPLPEPETRDEVAALVKALNGMLTRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
QEAFEAQTRFLQDASHELRTPITAILGHVGYLLRRTPLTEAQRESLEVVKREAERMGKLV
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
SDLLDLSQSGAWRIRPVPVRVLDLLEEVREEFAKSFDGEILVEAPEDLYVLGDPDRLHQV
HHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEECCHHHHHHH
MANLVSNALKAGARHVWLRAFDLGDKAVVRVEDDGEGIPEEHLPHLFERFYRVDKARDRE
HHHHHHHHHHHCCCEEEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHH
RGGSGLGLAIVKAILEAHGGEVWVESQVGKGTAFSFSLPASGPPPPPR
CCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]