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The map label for this gene is rocF [H]

Identifier: 55981465

GI number: 55981465

Start: 1423629

End: 1424504

Strand: Reverse

Name: rocF [H]

Synonym: TTHA1496

Alternate gene names: 55981465

Gene position: 1424504-1423629 (Counterclockwise)

Preceding gene: 55981466

Following gene: 55981462

Centisome position: 77.01

GC content: 72.15

Gene sequence:

>876_bases
ATGGAACGCGTGGCCGTGGTGGGCGTGCCCATGGACCTGGGGGCGAACCGGCGGGGCGTGGACATGGGGCCGTCCGCCCT
GCGGTACGCCCGGCTTCTGGAGCAGCTGGAGGATCTGGGCTACACCGTGGAGGACCTGGGGGACGTACCCGTCTCCCTGG
CCCGGGCCTCGAGGCGAAGGGGGCGGGGCCTCGCCTACCTGGAGGAGATCCGGGCCGCGGCCCTCGTCCTAAAGGAGCGC
CTTGCGGCCCTGCCCGAGGGGGTTTTCCCCATCGTCTTGGGCGGGGACCACTCCTTGAGCATGGGCTCCGTGGCGGGGGC
CGCCCGGGGCCGGCGGGTGGGCGTGGTCTGGGTGGACGCCCACGCCGACTTCAACACCCCCGAGACCTCGCCGAGCGGCA
ACGTCCACGGCATGCCCCTCGCCGTCCTCTCGGGCCTGGGCCATCCCCGGCTCACGGAGGTCTTCCGGGCCGTGGACCCC
AAGGACGTGGTCCTGGTGGGGGTGCGGAGCCTGGATCCCGGGGAGAAGCGCCTCCTTAAGGAGGCGGGGGTCCGGGTCTA
CACCATGCACGAGGTGGACCGCCTCGGCGTGGCCCGGATCGCCGAGGAGGTTCTAAAGCACCTCCAGGGCCTCCCCCTCC
ACGTCTCCCTGGACGCCGACGTCCTGGACCCCACCCTCGCCCCCGGGGTGGGGACCCCGGTGCCCGGGGGGCTCACCTAC
CGGGAGGCCCACCTCCTCATGGAGATCCTGGCCGAGTCGGGCCGGGTGCAGAGCCTGGACCTGGTGGAGGTGAACCCCAT
CCTGGACGAGCGCAACCGCACCGCCGAGATGCTGGTGGGCCTGGCGCTAAGCCTCTTGGGCAAGCGGATCTTTTAG

Upstream 100 bases:

>100_bases
GCCTTCCTCCTCCCCGAGGGGCAGGAGGTGGCCCTAGTGGTGCTCTAGGGCGCATAAACTTCCCAAGCCCCGCATGGACG
TTTCTGCTACCATGCCCCCC

Downstream 100 bases:

>100_bases
GCTACCCCAGGCCGGCCTGCCCTCTTTGGTTTCGCTAGGACGGCCGAAGGAAGGCCCTTTCGCCGCGGCGGGGCACCTAG
CCCGGCCTCGAGGCCCGCAC

Product: arginase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MERVAVVGVPMDLGANRRGVDMGPSALRYARLLEQLEDLGYTVEDLGDVPVSLARASRRRGRGLAYLEEIRAAALVLKER
LAALPEGVFPIVLGGDHSLSMGSVAGAARGRRVGVVWVDAHADFNTPETSPSGNVHGMPLAVLSGLGHPRLTEVFRAVDP
KDVVLVGVRSLDPGEKRLLKEAGVRVYTMHEVDRLGVARIAEEVLKHLQGLPLHVSLDADVLDPTLAPGVGTPVPGGLTY
REAHLLMEILAESGRVQSLDLVEVNPILDERNRTAEMLVGLALSLLGKRIF

Sequences:

>Translated_291_residues
MERVAVVGVPMDLGANRRGVDMGPSALRYARLLEQLEDLGYTVEDLGDVPVSLARASRRRGRGLAYLEEIRAAALVLKER
LAALPEGVFPIVLGGDHSLSMGSVAGAARGRRVGVVWVDAHADFNTPETSPSGNVHGMPLAVLSGLGHPRLTEVFRAVDP
KDVVLVGVRSLDPGEKRLLKEAGVRVYTMHEVDRLGVARIAEEVLKHLQGLPLHVSLDADVLDPTLAPGVGTPVPGGLTY
REAHLLMEILAESGRVQSLDLVEVNPILDERNRTAEMLVGLALSLLGKRIF
>Mature_291_residues
MERVAVVGVPMDLGANRRGVDMGPSALRYARLLEQLEDLGYTVEDLGDVPVSLARASRRRGRGLAYLEEIRAAALVLKER
LAALPEGVFPIVLGGDHSLSMGSVAGAARGRRVGVVWVDAHADFNTPETSPSGNVHGMPLAVLSGLGHPRLTEVFRAVDP
KDVVLVGVRSLDPGEKRLLKEAGVRVYTMHEVDRLGVARIAEEVLKHLQGLPLHVSLDADVLDPTLAPGVGTPVPGGLTY
REAHLLMEILAESGRVQSLDLVEVNPILDERNRTAEMLVGLALSLLGKRIF

Specific function: Controls arginine catabolism [H]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family [H]

Homologues:

Organism=Homo sapiens, GI10947139, Length=307, Percent_Identity=39.0879478827362, Blast_Score=204, Evalue=6e-53,
Organism=Homo sapiens, GI4502215, Length=301, Percent_Identity=36.8770764119601, Blast_Score=196, Evalue=3e-50,
Organism=Homo sapiens, GI37537722, Length=300, Percent_Identity=31.6666666666667, Blast_Score=97, Evalue=1e-20,
Organism=Escherichia coli, GI1789306, Length=279, Percent_Identity=26.8817204301075, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71996843, Length=203, Percent_Identity=35.9605911330049, Blast_Score=126, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6325146, Length=294, Percent_Identity=34.0136054421769, Blast_Score=162, Evalue=7e-41,
Organism=Drosophila melanogaster, GI24638886, Length=306, Percent_Identity=35.9477124183007, Blast_Score=167, Evalue=7e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014033
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.1 [H]

Molecular weight: Translated: 31230; Mature: 31230

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERVAVVGVPMDLGANRRGVDMGPSALRYARLLEQLEDLGYTVEDLGDVPVSLARASRRR
CCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHC
GRGLAYLEEIRAAALVLKERLAALPEGVFPIVLGGDHSLSMGSVAGAARGRRVGVVWVDA
CCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHCCCCEEEEEEEEC
HADFNTPETSPSGNVHGMPLAVLSGLGHPRLTEVFRAVDPKDVVLVGVRSLDPGEKRLLK
CCCCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHH
EAGVRVYTMHEVDRLGVARIAEEVLKHLQGLPLHVSLDADVLDPTLAPGVGTPVPGGLTY
HCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHCCCCCCCCCCCCCCCCCHH
REAHLLMEILAESGRVQSLDLVEVNPILDERNRTAEMLVGLALSLLGKRIF
HHHHHHHHHHHCCCCEEEEEEEEECCHHCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MERVAVVGVPMDLGANRRGVDMGPSALRYARLLEQLEDLGYTVEDLGDVPVSLARASRRR
CCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHC
GRGLAYLEEIRAAALVLKERLAALPEGVFPIVLGGDHSLSMGSVAGAARGRRVGVVWVDA
CCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHCCCCEEEEEEEEC
HADFNTPETSPSGNVHGMPLAVLSGLGHPRLTEVFRAVDPKDVVLVGVRSLDPGEKRLLK
CCCCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHH
EAGVRVYTMHEVDRLGVARIAEEVLKHLQGLPLHVSLDADVLDPTLAPGVGTPVPGGLTY
HCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHCCCCCCCCCCCCCCCCCHH
REAHLLMEILAESGRVQSLDLVEVNPILDERNRTAEMLVGLALSLLGKRIF
HHHHHHHHHHHCCCCEEEEEEEEECCHHCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8647285; 10196128 [H]