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The map label for this gene is cycZ [H]

Identifier: 55981375

GI number: 55981375

Start: 1338707

End: 1339393

Strand: Reverse

Name: cycZ [H]

Synonym: TTHA1406

Alternate gene names: 55981375

Gene position: 1339393-1338707 (Counterclockwise)

Preceding gene: 55981376

Following gene: 55981374

Centisome position: 72.41

GC content: 66.81

Gene sequence:

>687_bases
ATGCAGAAGACCGCGCTGCTTTCCCGCCCCGACGGCCTCACCTGGGCCTTCCTGGGGCTTGGGGTGTTGCTCCTTCCCCT
GGGGCTCTACCTCGCCCTCGCCGCGCCCCCGGACGCCAACCAGGGGTATTTGGTCCGGATCATGTACCTGCACGTTCCCA
CCGCCTGGGTGGGGTACCTGGCCTTTTTCGTCACCTTCCTCTACTCCCTTCTTTACCTCTTCCGCCAGGACCCGCGGCAC
GACCGGGTCGCCGCCGCAAGCGCCGAGATCGGCCTCGTCTTCATGGGCCTCGCCCTGGTGACGGGAATGCTCTGGGCCCG
GCCCACCTGGGGGGTCTACTGGACCTGGGAGCCCAGGCTCACCACCACGGCCATCCTCTTCGCCGTCTACGTGGGCTACT
TCCTCCTGCGGGGGGCCATTGAGGACCCCGAGCTTCGCCGCAAGGCGGCGGCGGCCGTGGGCGTTTTGGGCTTCCTCAAC
GTGCCCATAAGCTACATGTCGGTCAAGTGGTGGCGGAGCCTGCACCAGACCCAGTCCATTGACCTCACCACGGGCAAGAT
CCACATGGCCCCGGAGATGCTCCAGGTCCTCCTCTTCCACCTCGCCGTCTTCACGCTTCTGTACCTGGGCTTCGTCCGCT
TCCGCGGCCTGGTGGCGGCCCTGGAGGAAGCGAAGGAGGAGGCGTGA

Upstream 100 bases:

>100_bases
GCGAGCGCCCTCCTCTTCCCCCTGGTCATGGAGGGGTAGGGGGGTTTACAGAAACTTCACTTTCCCTTGGCTATCCTAGG
TGCTGAAGGAGGTTTGACCG

Downstream 100 bases:

>100_bases
TGGGGGTCTTCGTCACCTGGGTCTACGTCCTCACCTACCTCGCCGTCTTCGGCTACCTGGCCTACCTCTTCTGGCGGTAC
GGGAGGGCGCGGTGAAGGGG

Product: cytochrome C biogenesis protein, heme exporter protein

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CycZ [H]

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MQKTALLSRPDGLTWAFLGLGVLLLPLGLYLALAAPPDANQGYLVRIMYLHVPTAWVGYLAFFVTFLYSLLYLFRQDPRH
DRVAAASAEIGLVFMGLALVTGMLWARPTWGVYWTWEPRLTTTAILFAVYVGYFLLRGAIEDPELRRKAAAAVGVLGFLN
VPISYMSVKWWRSLHQTQSIDLTTGKIHMAPEMLQVLLFHLAVFTLLYLGFVRFRGLVAALEEAKEEA

Sequences:

>Translated_228_residues
MQKTALLSRPDGLTWAFLGLGVLLLPLGLYLALAAPPDANQGYLVRIMYLHVPTAWVGYLAFFVTFLYSLLYLFRQDPRH
DRVAAASAEIGLVFMGLALVTGMLWARPTWGVYWTWEPRLTTTAILFAVYVGYFLLRGAIEDPELRRKAAAAVGVLGFLN
VPISYMSVKWWRSLHQTQSIDLTTGKIHMAPEMLQVLLFHLAVFTLLYLGFVRFRGLVAALEEAKEEA
>Mature_228_residues
MQKTALLSRPDGLTWAFLGLGVLLLPLGLYLALAAPPDANQGYLVRIMYLHVPTAWVGYLAFFVTFLYSLLYLFRQDPRH
DRVAAASAEIGLVFMGLALVTGMLWARPTWGVYWTWEPRLTTTAILFAVYVGYFLLRGAIEDPELRRKAAAAVGVLGFLN
VPISYMSVKWWRSLHQTQSIDLTTGKIHMAPEMLQVLLFHLAVFTLLYLGFVRFRGLVAALEEAKEEA

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG0755

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmC/CycZ/HelC family [H]

Homologues:

Organism=Escherichia coli, GI1788527, Length=199, Percent_Identity=36.1809045226131, Blast_Score=108, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002541
- InterPro:   IPR003557 [H]

Pfam domain/function: PF01578 Cytochrom_C_asm [H]

EC number: NA

Molecular weight: Translated: 25639; Mature: 25639

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKTALLSRPDGLTWAFLGLGVLLLPLGLYLALAAPPDANQGYLVRIMYLHVPTAWVGYL
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEHHCCHHHHHHH
AFFVTFLYSLLYLFRQDPRHDRVAAASAEIGLVFMGLALVTGMLWARPTWGVYWTWEPRL
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCH
TTTAILFAVYVGYFLLRGAIEDPELRRKAAAAVGVLGFLNVPISYMSVKWWRSLHQTQSI
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCC
DLTTGKIHMAPEMLQVLLFHLAVFTLLYLGFVRFRGLVAALEEAKEEA
CEECCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQKTALLSRPDGLTWAFLGLGVLLLPLGLYLALAAPPDANQGYLVRIMYLHVPTAWVGYL
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEHHCCHHHHHHH
AFFVTFLYSLLYLFRQDPRHDRVAAASAEIGLVFMGLALVTGMLWARPTWGVYWTWEPRL
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCH
TTTAILFAVYVGYFLLRGAIEDPELRRKAAAAVGVLGFLNVPISYMSVKWWRSLHQTQSI
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCC
DLTTGKIHMAPEMLQVLLFHLAVFTLLYLGFVRFRGLVAALEEAKEEA
CEECCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1850420; 12597275 [H]