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The map label for this gene is prc [C]

Identifier: 55981265

GI number: 55981265

Start: 1236008

End: 1237327

Strand: Direct

Name: prc [C]

Synonym: TTHA1296

Alternate gene names: 55981265

Gene position: 1236008-1237327 (Clockwise)

Preceding gene: 55981261

Following gene: 55981278

Centisome position: 66.82

GC content: 67.8

Gene sequence:

>1320_bases
ATGAAGCGACGCGCGTGGTTCATGGTAGGGCTCGGGGCGCTCCTCGCCCTGGTGTACGCCCAGCTTCCCCGGCCTCAGGC
GGAGACCTTCCTGCAGAACCCCAACGGCCAGGCCCTCCTGGAGGTCTACCAGAGGATCCAACAGGACTACCTGGAGCCCC
TCTCCAAGGAGAAGCTGGACAAGCTCCTGGAAGGGGCCATCGGCGGGATGGTCCAGGCCCTCGAGGACCCCTTCACCAGC
TACTCCCCGCCCCAGCGCTCCACCCTGCGCCAAGAGGACCTAAGGGGCGAGTTCTTCGGCATCGGGGCCACCCTCTCGGC
CGCGAACCCCGACGGCACGGGAGCGCGGATTGAGGGGGTCATGAAGGGGCTTCCCGCCCAGCGGGCGGGCCTCAGGGCCG
GGGACGTGATTTTGGAGGTGGACGGGGAGGACGTGACCAAGCTCCCCCTCCTGGACATCGTGGCGAAGATCCGGGGGCGG
GAGGGAACCAAGGTCACCCTGAAGGTGCGGCGGGAAGGCGTGCCCGCCCCCCTGGTCTTTGAGCTCGTGCGCGAGCGGGT
GGAGATCATCTCCGTGTCCACCGCCAAGGTGGGGGACGTGGGCTACGTGGCCCTGGAAACCTTCGCCAACTTCAAGGTGG
AGGACCAGCTGAAGCGGGCCATAGAAGAGCTCAAGGCCCAGGGCGTGAAGAAGCTGATCTTTGACCTGAGGGACAACGGC
GGAGGGCTCCTGGACCAGGGGTGCGCCGTGGCCAGCGCCTTCCTCAAGGAGGGCCCCATCGTCTACACCCGCACCAAGAA
CCTCACCCGCGTCTGGTGCGAGGCCACGGGCCAAACCCTCTGGGACGGGCCCATGGTGGTCCTGGTGAACGGCAACTCCG
CTTCGGCGAGCGAGATCGTGGCCGGGGCCCTCCAGGACTACGGCCGGGCCAAGGTCATCGGGGAGAAGACCTTCGGCAAG
GGCGTGGGCCAGACCCCCTACACCCTGGCGAACGGCGGGGAGCTCACCCTGGTCACCTTTGAGTGGCTCACCCCCAAGCG
CCGCTCCATCAACAAGGAGGGGATCACCCCGGACATCGTGGTGAAGGACACCCGCTTCCCCACGCCCTTCTCCCTGCAAG
GGGCGGGGGCGCCGCCGGGGGCGGAGATCGCCGTGACCCTGAACGGCAAGACCGTCAAGGTGAAGGCGGACGCGGAAGGC
AAGTTCTCCTACGCCGAGCCGCAGCGGCAGAGGCCTCTTCCCGAGGACCGGGGCCAGGCGGTTCTGGACCTGGAGAACGA
CGCCATCCTCAAGCGGGCCCTGGAGGAGCTAAACCGCTAG

Upstream 100 bases:

>100_bases
GGGTACTCCAGGCCCACCCGGTGGAAGGCGATCATGCCCCCACTATACGCACCTTCCTCTCAGGAAAAGGCGCTATAGTG
GGGCTCAGGTGAGGGAGAAG

Downstream 100 bases:

>100_bases
GCGCCACACGATCCTGGGGGGCCTAAACCCGAGGGCCCCCCAGGTTCTCTTCCAGGAAACGGAGAAGGGCGATGCAGTAG
GTGGTGAAAAAGTTCTTCTC

Product: carboxyl-terminal protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MKRRAWFMVGLGALLALVYAQLPRPQAETFLQNPNGQALLEVYQRIQQDYLEPLSKEKLDKLLEGAIGGMVQALEDPFTS
YSPPQRSTLRQEDLRGEFFGIGATLSAANPDGTGARIEGVMKGLPAQRAGLRAGDVILEVDGEDVTKLPLLDIVAKIRGR
EGTKVTLKVRREGVPAPLVFELVRERVEIISVSTAKVGDVGYVALETFANFKVEDQLKRAIEELKAQGVKKLIFDLRDNG
GGLLDQGCAVASAFLKEGPIVYTRTKNLTRVWCEATGQTLWDGPMVVLVNGNSASASEIVAGALQDYGRAKVIGEKTFGK
GVGQTPYTLANGGELTLVTFEWLTPKRRSINKEGITPDIVVKDTRFPTPFSLQGAGAPPGAEIAVTLNGKTVKVKADAEG
KFSYAEPQRQRPLPEDRGQAVLDLENDAILKRALEELNR

Sequences:

>Translated_439_residues
MKRRAWFMVGLGALLALVYAQLPRPQAETFLQNPNGQALLEVYQRIQQDYLEPLSKEKLDKLLEGAIGGMVQALEDPFTS
YSPPQRSTLRQEDLRGEFFGIGATLSAANPDGTGARIEGVMKGLPAQRAGLRAGDVILEVDGEDVTKLPLLDIVAKIRGR
EGTKVTLKVRREGVPAPLVFELVRERVEIISVSTAKVGDVGYVALETFANFKVEDQLKRAIEELKAQGVKKLIFDLRDNG
GGLLDQGCAVASAFLKEGPIVYTRTKNLTRVWCEATGQTLWDGPMVVLVNGNSASASEIVAGALQDYGRAKVIGEKTFGK
GVGQTPYTLANGGELTLVTFEWLTPKRRSINKEGITPDIVVKDTRFPTPFSLQGAGAPPGAEIAVTLNGKTVKVKADAEG
KFSYAEPQRQRPLPEDRGQAVLDLENDAILKRALEELNR
>Mature_439_residues
MKRRAWFMVGLGALLALVYAQLPRPQAETFLQNPNGQALLEVYQRIQQDYLEPLSKEKLDKLLEGAIGGMVQALEDPFTS
YSPPQRSTLRQEDLRGEFFGIGATLSAANPDGTGARIEGVMKGLPAQRAGLRAGDVILEVDGEDVTKLPLLDIVAKIRGR
EGTKVTLKVRREGVPAPLVFELVRERVEIISVSTAKVGDVGYVALETFANFKVEDQLKRAIEELKAQGVKKLIFDLRDNG
GGLLDQGCAVASAFLKEGPIVYTRTKNLTRVWCEATGQTLWDGPMVVLVNGNSASASEIVAGALQDYGRAKVIGEKTFGK
GVGQTPYTLANGGELTLVTFEWLTPKRRSINKEGITPDIVVKDTRFPTPFSLQGAGAPPGAEIAVTLNGKTVKVKADAEG
KFSYAEPQRQRPLPEDRGQAVLDLENDAILKRALEELNR

Specific function: Involved In The Cleavage Of A C-Terminal Peptide Of 11 Residues From The Precursor Form Of Penicillin-Binding Protein 3 (Pbp3). May Be Involved In Protection Of The Bacterium From Thermal And Osmotic Stresses. [C]

COG id: COG0793

COG function: function code M; Periplasmic protease

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1788134, Length=313, Percent_Identity=33.8658146964856, Blast_Score=131, Evalue=7e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR005151
- InterPro:   IPR004447
- InterPro:   IPR002477 [H]

Pfam domain/function: PF00595 PDZ; PF03572 Peptidase_S41; PF01471 PG_binding_1 [H]

EC number: 3.4.21.102 [C]

Molecular weight: Translated: 47723; Mature: 47723

Theoretical pI: Translated: 8.13; Mature: 8.13

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRRAWFMVGLGALLALVYAQLPRPQAETFLQNPNGQALLEVYQRIQQDYLEPLSKEKLD
CCCCEEHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
KLLEGAIGGMVQALEDPFTSYSPPQRSTLRQEDLRGEFFGIGATLSAANPDGTGARIEGV
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEECEEEECCCCCCCCHHHHHH
MKGLPAQRAGLRAGDVILEVDGEDVTKLPLLDIVAKIRGREGTKVTLKVRREGVPAPLVF
HHCCCHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHH
ELVRERVEIISVSTAKVGDVGYVALETFANFKVEDQLKRAIEELKAQGVKKLIFDLRDNG
HHHHHHHHHEEECCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GGLLDQGCAVASAFLKEGPIVYTRTKNLTRVWCEATGQTLWDGPMVVLVNGNSASASEIV
CCCHHHHHHHHHHHHHCCCEEEEECCCCEEEEEHHCCCEEECCCEEEEEECCCCCHHHHH
AGALQDYGRAKVIGEKTFGKGVGQTPYTLANGGELTLVTFEWLTPKRRSINKEGITPDIV
HHHHHHCCCEEEECCHHHCCCCCCCCEEEECCCEEEEEEEECCCCHHHCCCCCCCCCCEE
VKDTRFPTPFSLQGAGAPPGAEIAVTLNGKTVKVKADAEGKFSYAEPQRQRPLPEDRGQA
EECCCCCCCCCCCCCCCCCCCEEEEEECCEEEEEEECCCCCCCCCCCHHCCCCCCCCCCE
VLDLENDAILKRALEELNR
EEEECCHHHHHHHHHHHCC
>Mature Secondary Structure
MKRRAWFMVGLGALLALVYAQLPRPQAETFLQNPNGQALLEVYQRIQQDYLEPLSKEKLD
CCCCEEHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
KLLEGAIGGMVQALEDPFTSYSPPQRSTLRQEDLRGEFFGIGATLSAANPDGTGARIEGV
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEECEEEECCCCCCCCHHHHHH
MKGLPAQRAGLRAGDVILEVDGEDVTKLPLLDIVAKIRGREGTKVTLKVRREGVPAPLVF
HHCCCHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHH
ELVRERVEIISVSTAKVGDVGYVALETFANFKVEDQLKRAIEELKAQGVKKLIFDLRDNG
HHHHHHHHHEEECCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GGLLDQGCAVASAFLKEGPIVYTRTKNLTRVWCEATGQTLWDGPMVVLVNGNSASASEIV
CCCHHHHHHHHHHHHHCCCEEEEECCCCEEEEEHHCCCEEECCCEEEEEECCCCCHHHHH
AGALQDYGRAKVIGEKTFGKGVGQTPYTLANGGELTLVTFEWLTPKRRSINKEGITPDIV
HHHHHHCCCEEEECCHHHCCCCCCCCEEEECCCEEEEEEEECCCCHHHCCCCCCCCCCEE
VKDTRFPTPFSLQGAGAPPGAEIAVTLNGKTVKVKADAEGKFSYAEPQRQRPLPEDRGQA
EECCCCCCCCCCCCCCCCCCCEEEEEECCEEEEEEECCCCCCCCCCCHHCCCCCCCCCCE
VLDLENDAILKRALEELNR
EEEECCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Cleavage of the C-terminal peptide from the precursor form of penicillin-binding protein 3 [C]

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA