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The map label for this gene is recG [H]

Identifier: 55981235

GI number: 55981235

Start: 1207342

End: 1209654

Strand: Direct

Name: recG [H]

Synonym: TTHA1266

Alternate gene names: 55981235

Gene position: 1207342-1209654 (Clockwise)

Preceding gene: 55981229

Following gene: 55981236

Centisome position: 65.27

GC content: 69.69

Gene sequence:

>2313_bases
ATGGAAGGCGTGACGCAAGAGGAGCTCAAGGCCAGGCTCCTCAAGCCCCTTCTCCGGGAGCTCCAGGACGGGGCCAGGGA
CCGGGTGGTGGTGGGGGGCCTCGAGGCCTTGGTGCAGAACCTCGCCCGCCCCTTCCCCAAGCTCCTGGAGCTCTTCCGGG
GCTACGGGGAAAAGCCCCAGGAAGAGCGGAAGCGGGTCTTGCAGGAGGCCCTCCGCCTCCTGGAGGGCCAAGGCCCCTCC
CCAAAGGGCCAGGCCCAGGCCTCCTCCAGGAGGCTCGCCCCTTCCGATCCCGCCCACCTCCTCGCCCCCCCGCAAAGCCG
GAGGAAGCTTGCCGAGCTCGGCCTGCGCACGGTGCGGGACGTCCTCCACCACTACCCCCGCCGCTACGAGGACCGCCGGG
CCCTCCCCGGGGCGCGCTACCTGGAGGAGGGGCAGAAGGCCACCCTGGCCGTGAAGGTCCTCGCCAAGGAGCTCGTCAAG
ACCCCCAGGAAGGGGATGCAGCTCGTCCAGGTGAAGGCCCAGGACGCCTGGGGGTGGCGCATCACCCTGGTCTGGTTCAA
CCAGCCCTGGGTCCTCTCCCAGATTGAGGAGGGGGCCACCCTCATCGTCACCGGGAGGGTGGGGCGGCGAAACGGCCTCC
AGCTCTACGTGGAGCACTTTGAGGACGAGGGCACCGAGTCGCTTTCCACCGGGCGGATCGTCCCCATCTACCCCGCCAAG
GAGGGGGTAAGCCAGGCCTTCCTCCGCCGCACCGTCCACAGGGCCCTGGAGCTCGCCCTCCCCCTCCCCGACCCCCTGGA
GGCCTACCGGGAGGACCTGGGCCTCATGCCCTACGCCGAGGCCCTGAAGGCCATCCACTTCCCCGAGGACGAGGAGGCCC
TGAAGCGGGCCCTCCTCCGCCTCAAGTTTGACGAGTACCTCCTCCTGGAGCTCAAGGCCCTCCTGGAGGCGGGAGGAATG
GTCCTCGGCCGGAGCTTCCGGGTGGAGGAGGCCTGGGTGGAGGCCTTCAAAAAGGCCCTCCCCTTCCCCCTCACCCGGGC
CCAGGAACGGGTCATGGGGGAGATCGCCAAGGACATGCAAAGCCCCCGCCAGATGGCCCGCCTCCTCCAGGGGGACGTGG
GCTCGGGGAAGACGGTGGTGGCGGCCTTCGCCCTCTTCCTCGCGGCCAAGAACGGGGCCCAGGGGGCCCTCATGGCCCCC
ACGGAGATCCTGGCCCGGCAGCACTACCAGAACCTCACCCGCTACCTCTTCCCCTTGGGGATCAGGGTGGAGCTCCTCCT
GGGCTCCATGACGGCCAAGGAGAAGGAGGCCGCCATGGCCCGGCTCCTCTCGGGGGAGGCCCAGGTGGCCGTGGGCACCC
ACGCCCTCATCCAGGAGGGGGTGGGCTTCAGGGACCTGGGCCTCGCCGTGGTGGACGAGGAGCACCGCTTCGGGGTCCTG
CAGCGCCGGGCCCTCCTCAAGCTGGCCAAGGCGCCGCCGGACGTCCTCGTCATGTCCGCCACCCCCATCCCCCGCTCCCT
GGCCTTAACCCTCTACGGGGACCTCGAGGTGAGCGTCCTGGACGAGATGCCCCCAGGACGCGTCCCGGTGAAGACCAAGG
TCCTCCCCCACCGCCTCCGCCTCCAGGCCTACGCCTTCGCCCGGGAGGAGGTGAGAAAGGGCCACCAGGTCTTCGTGGTG
GCCCCGGCCATTGAGGAGAGCGAGGAGCTGGACCTAAAGGCGGCCACCACCCTCTACGAGGAGCTTAAAGGCCTCCTCCC
TGGGGTGCGCCTGGCCCTCCTCCACGGGAGGATGCCCGCCCGGGAGAAGGACGAGGTGATGGAGGCCTTCCGGCGCGGGG
ACTACGACCTTTTGGTCTCCACCACGGTGGTGGAGGTGGGGGTGGACATCCCCAAGGCCACCCTCATCATCGTGGAGAAC
GCCGAGCGCTTCGGCCTCGCCCAGCTCCACCAGCTAAGGGGCCGGGTGGGCCGGGGGGGGCTTGAGGGCTACGCCGTCTT
CATCGCGGGGGAGGCGGGCCAGAAGACCCTGAAGCGCCTCAAGATCCTGGAGGAGTCCACGGACGGCTTTTACATCGCCG
AGATGGACCTGAAGCTCAGGGGCCCTGGGGAGCTTCGCGGCACGCGGCAGTCAGGCTACCCCGAGCTCAAGCTCGGCGAC
CTCGCCGAGGACACGGGGATCATTGAGAAGGCCCGGGCTTTGGCCAAGGCCATCGTGGACAAGGACCCCACCCTGGACCT
CCCCGAGCACCGGGCCCTCAAGGAGGAGCTCAGGGCCCAGGCGGAGCGGGTGGGGTTCCGGGAAGTGATCTGA

Upstream 100 bases:

>100_bases
CCAGAAGCTGGAAGGCAACCCCGGGGAAGTCCCGCTCCTCCAGGGCCACCACCAGGCCGTTGGGTAGGCGCTCCACGCGG
CTCACAGGCCTAAGGGTATC

Downstream 100 bases:

>100_bases
TGCGGGCCCTCCCCCACCCCCACCTCCCCGCCTTCTTCTCCGAGGGCGGGGCCCTAAGGGCCAAGGCCCTCCAGGACTAC
CTCCTCTCCCTAAGGGAGGT

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 770; Mature: 770

Protein sequence:

>770_residues
MEGVTQEELKARLLKPLLRELQDGARDRVVVGGLEALVQNLARPFPKLLELFRGYGEKPQEERKRVLQEALRLLEGQGPS
PKGQAQASSRRLAPSDPAHLLAPPQSRRKLAELGLRTVRDVLHHYPRRYEDRRALPGARYLEEGQKATLAVKVLAKELVK
TPRKGMQLVQVKAQDAWGWRITLVWFNQPWVLSQIEEGATLIVTGRVGRRNGLQLYVEHFEDEGTESLSTGRIVPIYPAK
EGVSQAFLRRTVHRALELALPLPDPLEAYREDLGLMPYAEALKAIHFPEDEEALKRALLRLKFDEYLLLELKALLEAGGM
VLGRSFRVEEAWVEAFKKALPFPLTRAQERVMGEIAKDMQSPRQMARLLQGDVGSGKTVVAAFALFLAAKNGAQGALMAP
TEILARQHYQNLTRYLFPLGIRVELLLGSMTAKEKEAAMARLLSGEAQVAVGTHALIQEGVGFRDLGLAVVDEEHRFGVL
QRRALLKLAKAPPDVLVMSATPIPRSLALTLYGDLEVSVLDEMPPGRVPVKTKVLPHRLRLQAYAFAREEVRKGHQVFVV
APAIEESEELDLKAATTLYEELKGLLPGVRLALLHGRMPAREKDEVMEAFRRGDYDLLVSTTVVEVGVDIPKATLIIVEN
AERFGLAQLHQLRGRVGRGGLEGYAVFIAGEAGQKTLKRLKILEESTDGFYIAEMDLKLRGPGELRGTRQSGYPELKLGD
LAEDTGIIEKARALAKAIVDKDPTLDLPEHRALKEELRAQAERVGFREVI

Sequences:

>Translated_770_residues
MEGVTQEELKARLLKPLLRELQDGARDRVVVGGLEALVQNLARPFPKLLELFRGYGEKPQEERKRVLQEALRLLEGQGPS
PKGQAQASSRRLAPSDPAHLLAPPQSRRKLAELGLRTVRDVLHHYPRRYEDRRALPGARYLEEGQKATLAVKVLAKELVK
TPRKGMQLVQVKAQDAWGWRITLVWFNQPWVLSQIEEGATLIVTGRVGRRNGLQLYVEHFEDEGTESLSTGRIVPIYPAK
EGVSQAFLRRTVHRALELALPLPDPLEAYREDLGLMPYAEALKAIHFPEDEEALKRALLRLKFDEYLLLELKALLEAGGM
VLGRSFRVEEAWVEAFKKALPFPLTRAQERVMGEIAKDMQSPRQMARLLQGDVGSGKTVVAAFALFLAAKNGAQGALMAP
TEILARQHYQNLTRYLFPLGIRVELLLGSMTAKEKEAAMARLLSGEAQVAVGTHALIQEGVGFRDLGLAVVDEEHRFGVL
QRRALLKLAKAPPDVLVMSATPIPRSLALTLYGDLEVSVLDEMPPGRVPVKTKVLPHRLRLQAYAFAREEVRKGHQVFVV
APAIEESEELDLKAATTLYEELKGLLPGVRLALLHGRMPAREKDEVMEAFRRGDYDLLVSTTVVEVGVDIPKATLIIVEN
AERFGLAQLHQLRGRVGRGGLEGYAVFIAGEAGQKTLKRLKILEESTDGFYIAEMDLKLRGPGELRGTRQSGYPELKLGD
LAEDTGIIEKARALAKAIVDKDPTLDLPEHRALKEELRAQAERVGFREVI
>Mature_770_residues
MEGVTQEELKARLLKPLLRELQDGARDRVVVGGLEALVQNLARPFPKLLELFRGYGEKPQEERKRVLQEALRLLEGQGPS
PKGQAQASSRRLAPSDPAHLLAPPQSRRKLAELGLRTVRDVLHHYPRRYEDRRALPGARYLEEGQKATLAVKVLAKELVK
TPRKGMQLVQVKAQDAWGWRITLVWFNQPWVLSQIEEGATLIVTGRVGRRNGLQLYVEHFEDEGTESLSTGRIVPIYPAK
EGVSQAFLRRTVHRALELALPLPDPLEAYREDLGLMPYAEALKAIHFPEDEEALKRALLRLKFDEYLLLELKALLEAGGM
VLGRSFRVEEAWVEAFKKALPFPLTRAQERVMGEIAKDMQSPRQMARLLQGDVGSGKTVVAAFALFLAAKNGAQGALMAP
TEILARQHYQNLTRYLFPLGIRVELLLGSMTAKEKEAAMARLLSGEAQVAVGTHALIQEGVGFRDLGLAVVDEEHRFGVL
QRRALLKLAKAPPDVLVMSATPIPRSLALTLYGDLEVSVLDEMPPGRVPVKTKVLPHRLRLQAYAFAREEVRKGHQVFVV
APAIEESEELDLKAATTLYEELKGLLPGVRLALLHGRMPAREKDEVMEAFRRGDYDLLVSTTVVEVGVDIPKATLIIVEN
AERFGLAQLHQLRGRVGRGGLEGYAVFIAGEAGQKTLKRLKILEESTDGFYIAEMDLKLRGPGELRGTRQSGYPELKLGD
LAEDTGIIEKARALAKAIVDKDPTLDLPEHRALKEELRAQAERVGFREVI

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=682, Percent_Identity=40.7624633431085, Blast_Score=409, Evalue=1e-115,
Organism=Escherichia coli, GI1787357, Length=399, Percent_Identity=39.8496240601504, Blast_Score=268, Evalue=1e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 85747; Mature: 85747

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGVTQEELKARLLKPLLRELQDGARDRVVVGGLEALVQNLARPFPKLLELFRGYGEKPQ
CCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCH
EERKRVLQEALRLLEGQGPSPKGQAQASSRRLAPSDPAHLLAPPQSRRKLAELGLRTVRD
HHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
VLHHYPRRYEDRRALPGARYLEEGQKATLAVKVLAKELVKTPRKGMQLVQVKAQDAWGWR
HHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHCHHHCCEEEEEEECCCCCEE
ITLVWFNQPWVLSQIEEGATLIVTGRVGRRNGLQLYVEHFEDEGTESLSTGRIVPIYPAK
EEEEEECCCHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEECCCH
EGVSQAFLRRTVHRALELALPLPDPLEAYREDLGLMPYAEALKAIHFPEDEEALKRALLR
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHH
LKFDEYLLLELKALLEAGGMVLGRSFRVEEAWVEAFKKALPFPLTRAQERVMGEIAKDMQ
HCCHHHHHHHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
SPRQMARLLQGDVGSGKTVVAAFALFLAAKNGAQGALMAPTEILARQHYQNLTRYLFPLG
CHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCEECHHHHHHHHHHHHHHHHHHCCC
IRVELLLGSMTAKEKEAAMARLLSGEAQVAVGTHALIQEGVGFRDLGLAVVDEEHRFGVL
CEEEHHHHHHCHHHHHHHHHHHHCCCCEEEHHHHHHHHCCCCCHHCCEEEECCHHHHHHH
QRRALLKLAKAPPDVLVMSATPIPRSLALTLYGDLEVSVLDEMPPGRVPVKTKVLPHRLR
HHHHHHHHHCCCCCEEEEECCCCCCEEEEEEECCCEEEECCCCCCCCCCEEECCCHHHHH
LQAYAFAREEVRKGHQVFVVAPAIEESEELDLKAATTLYEELKGLLPGVRLALLHGRMPA
HHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCC
REKDEVMEAFRRGDYDLLVSTTVVEVGVDIPKATLIIVENAERFGLAQLHQLRGRVGRGG
CCHHHHHHHHHCCCCEEEEEHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCC
LEGYAVFIAGEAGQKTLKRLKILEESTDGFYIAEMDLKLRGPGELRGTRQSGYPELKLGD
CCEEEEEEECCCCHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCEECC
LAEDTGIIEKARALAKAIVDKDPTLDLPEHRALKEELRAQAERVGFREVI
CHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCHHHCC
>Mature Secondary Structure
MEGVTQEELKARLLKPLLRELQDGARDRVVVGGLEALVQNLARPFPKLLELFRGYGEKPQ
CCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCH
EERKRVLQEALRLLEGQGPSPKGQAQASSRRLAPSDPAHLLAPPQSRRKLAELGLRTVRD
HHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
VLHHYPRRYEDRRALPGARYLEEGQKATLAVKVLAKELVKTPRKGMQLVQVKAQDAWGWR
HHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHCHHHCCEEEEEEECCCCCEE
ITLVWFNQPWVLSQIEEGATLIVTGRVGRRNGLQLYVEHFEDEGTESLSTGRIVPIYPAK
EEEEEECCCHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEECCCH
EGVSQAFLRRTVHRALELALPLPDPLEAYREDLGLMPYAEALKAIHFPEDEEALKRALLR
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHH
LKFDEYLLLELKALLEAGGMVLGRSFRVEEAWVEAFKKALPFPLTRAQERVMGEIAKDMQ
HCCHHHHHHHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
SPRQMARLLQGDVGSGKTVVAAFALFLAAKNGAQGALMAPTEILARQHYQNLTRYLFPLG
CHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCEECHHHHHHHHHHHHHHHHHHCCC
IRVELLLGSMTAKEKEAAMARLLSGEAQVAVGTHALIQEGVGFRDLGLAVVDEEHRFGVL
CEEEHHHHHHCHHHHHHHHHHHHCCCCEEEHHHHHHHHCCCCCHHCCEEEECCHHHHHHH
QRRALLKLAKAPPDVLVMSATPIPRSLALTLYGDLEVSVLDEMPPGRVPVKTKVLPHRLR
HHHHHHHHHCCCCCEEEEECCCCCCEEEEEEECCCEEEECCCCCCCCCCEEECCCHHHHH
LQAYAFAREEVRKGHQVFVVAPAIEESEELDLKAATTLYEELKGLLPGVRLALLHGRMPA
HHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCC
REKDEVMEAFRRGDYDLLVSTTVVEVGVDIPKATLIIVENAERFGLAQLHQLRGRVGRGG
CCHHHHHHHHHCCCCEEEEEHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCC
LEGYAVFIAGEAGQKTLKRLKILEESTDGFYIAEMDLKLRGPGELRGTRQSGYPELKLGD
CCEEEEEEECCCCHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCEECC
LAEDTGIIEKARALAKAIVDKDPTLDLPEHRALKEELRAQAERVGFREVI
CHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]