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The map label for this gene is dnaG [H]

Identifier: 55981229

GI number: 55981229

Start: 1199805

End: 1201577

Strand: Direct

Name: dnaG [H]

Synonym: TTHA1260

Alternate gene names: 55981229

Gene position: 1199805-1201577 (Clockwise)

Preceding gene: 55981228

Following gene: 55981235

Centisome position: 64.86

GC content: 71.35

Gene sequence:

>1773_bases
ATGGACGCGGGCCAGGCGGTGGAGCTGATCAAGTCCCGCCTCTCCTTGCGGGAGGTGGTCTCCCGCTACGTGGCCCTGAA
GCCGGCGGGCCGCGGCCGCTGGAAGGGCCTCTGCCCCTTCCACCAGGAGAAGACCCCCTCTTTCTACGTGGACGAGGAGA
AGGGCCTCTTCTACTGCTTCGGGTGCAAGGCCGGGGGCGACCTCTTCGCCTTCGTCCAAAGGGCGGAGGGGCTGGACTTC
CCCGAGGCCCTGGAAAGGCTCGCGGAGGAGGCGGGGGTGGAGCTTCCCCGGCGGAAGGCCCCGGAAAGGCGCCGGGAGCT
CCTCGAGGTCCTGGCCCTGGCCCAGACCTACTTCCTGGAGCACCTCCACGCCCACCCCGAGGCCCTGGCCTACCTGAGGA
AGCGGGGCCTCACGGAGGAGAGCGTGGCCCGCTTCGGCCTGGGCTACGCCCCGCCCAAGGGGGACGGGCTCGTGGCCTTC
CTCGCCCGGCACGGGGTGGCCCCGGAGGAGGGCGTGCGGGCCGGGGTGCTGGCGGAGCGGCAGGGGCGCTTCGTGGACCG
CCTCCGCCACCGCATCACCTTCCCCATCAAGGACGCCTTCGGGCGCGTCGTGGCCTTCACCGGGAGGGCCCTGGGGGAGG
ACGGGCCCAAGTACCTGAACACCCCCGAAACCCCCCTTTTCCGCAAGCAGGAGGTCCTCTTCGCCTACCCCGAGGCCCGG
CCCGCCTTGAGGGAGGGCCGGGCCATCGTGGTGGAGGGGCTCTTTGACGCCATCGCCCTCCACCAGCTGGGCTTCCCGGA
GACGGTGGCCGTGCTGGGCTCGGGCCTCTCCGAGGGACAGGCCCTCCTCCTCAAGAAGGCGGGGGTCCTGGAGGTCTACC
TGGCCTTTGACGCCGACGAGGCCGGGCAGAAGGCCACCTTGCAGAGCCTGAACCTGGAGCTCGCCCCCAGGTTCCTCTTC
TACGCCGTCCGCCTCCCCGCCAAGGACCCGGGGGAGCTCCTCCTCCACCCCGAGGGAAGGGCCCTCTTCCAGAAGGCCCT
GGAGGAGGCCCTCCCCGAGGTGGCCTTCCGCTTTGAGGAGGCGAGCCGGGGGCTGGACCTCTCCCGGCCCGAGCACAAGC
GGAAGGTCCTCGAGGCCCTCACCCCGAGGATGCTCACCCCGGAGCCCTTTGATCCCGTGGCCGAGCGGCTCAAGGCCCTG
GTGGTGGAGCGCCTGGGCCTTTCCCCCAAGAGCCTCGAGGACTACCTGGCGAGCCTTAGGACCCGGGGGCGGCCCGCCCC
TCCCCCACCGCCCCCACCCCCCATCCCCGGCAACAAGACCCTCCTTCTGGAGCTGGACGCCATCGCCCTCCTCCTCTCCG
CCCCGGAGGAGCGCTTCCTGGAGCTTGTGGACTACGTGGAGACCCAGGTCTGGCCCCCGGAGGGTTCCTTCCTCGGGGAG
TTCCTGGCCCTGGCCCGGAAGGAGCCCCGGCGGGACCACCTCCGCCGCACCCTAAGCCAGCGGGAGGAAGGAGGAAGGCT
CTTTGAGCGCCTGCTCCTCGCGCCCCGGGGGGAGGATCCCAGGCTCCAGGAGAAGCTGGACCACACCCTGGCCCGCCTGC
GGGAAGCCTACCTCCAGGAGCGGCTCGCCAAGGTCAAGGCGGCCCTCGCCCAAAACCCCGACCCCCCCACCCTGGAGCGC
CTCCTTAAGGAGTACCAGGAGATCCGGGTGGCCATAGAGGCGGAGCGCCGCCTCTACAAGCGGCGCCCCCCTCCTTCGGG
CTGGTCCACCTAG

Upstream 100 bases:

>100_bases
CCTGGAAGGCCGCCCTCCAGGGCCAGGAAGCCGCCGAGGACCTGGAGGGGTACGGTATCCTGGGGAGGTGGGTCAGGAGG
CTTTGGCGTAGGGGGGCGGC

Downstream 100 bases:

>100_bases
AGCCGTTCCGTGGCCTCGGCCATGGCCCTAAGCCTCGCCCCGTGCTCCGGGGAAAGCTCCCCCGGGAGGAGCCGCCAGGC
CCAGTTCCCCGAGGGCCTTC

Product: DNA primase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 590; Mature: 590

Protein sequence:

>590_residues
MDAGQAVELIKSRLSLREVVSRYVALKPAGRGRWKGLCPFHQEKTPSFYVDEEKGLFYCFGCKAGGDLFAFVQRAEGLDF
PEALERLAEEAGVELPRRKAPERRRELLEVLALAQTYFLEHLHAHPEALAYLRKRGLTEESVARFGLGYAPPKGDGLVAF
LARHGVAPEEGVRAGVLAERQGRFVDRLRHRITFPIKDAFGRVVAFTGRALGEDGPKYLNTPETPLFRKQEVLFAYPEAR
PALREGRAIVVEGLFDAIALHQLGFPETVAVLGSGLSEGQALLLKKAGVLEVYLAFDADEAGQKATLQSLNLELAPRFLF
YAVRLPAKDPGELLLHPEGRALFQKALEEALPEVAFRFEEASRGLDLSRPEHKRKVLEALTPRMLTPEPFDPVAERLKAL
VVERLGLSPKSLEDYLASLRTRGRPAPPPPPPPPIPGNKTLLLELDAIALLLSAPEERFLELVDYVETQVWPPEGSFLGE
FLALARKEPRRDHLRRTLSQREEGGRLFERLLLAPRGEDPRLQEKLDHTLARLREAYLQERLAKVKAALAQNPDPPTLER
LLKEYQEIRVAIEAERRLYKRRPPPSGWST

Sequences:

>Translated_590_residues
MDAGQAVELIKSRLSLREVVSRYVALKPAGRGRWKGLCPFHQEKTPSFYVDEEKGLFYCFGCKAGGDLFAFVQRAEGLDF
PEALERLAEEAGVELPRRKAPERRRELLEVLALAQTYFLEHLHAHPEALAYLRKRGLTEESVARFGLGYAPPKGDGLVAF
LARHGVAPEEGVRAGVLAERQGRFVDRLRHRITFPIKDAFGRVVAFTGRALGEDGPKYLNTPETPLFRKQEVLFAYPEAR
PALREGRAIVVEGLFDAIALHQLGFPETVAVLGSGLSEGQALLLKKAGVLEVYLAFDADEAGQKATLQSLNLELAPRFLF
YAVRLPAKDPGELLLHPEGRALFQKALEEALPEVAFRFEEASRGLDLSRPEHKRKVLEALTPRMLTPEPFDPVAERLKAL
VVERLGLSPKSLEDYLASLRTRGRPAPPPPPPPPIPGNKTLLLELDAIALLLSAPEERFLELVDYVETQVWPPEGSFLGE
FLALARKEPRRDHLRRTLSQREEGGRLFERLLLAPRGEDPRLQEKLDHTLARLREAYLQERLAKVKAALAQNPDPPTLER
LLKEYQEIRVAIEAERRLYKRRPPPSGWST
>Mature_590_residues
MDAGQAVELIKSRLSLREVVSRYVALKPAGRGRWKGLCPFHQEKTPSFYVDEEKGLFYCFGCKAGGDLFAFVQRAEGLDF
PEALERLAEEAGVELPRRKAPERRRELLEVLALAQTYFLEHLHAHPEALAYLRKRGLTEESVARFGLGYAPPKGDGLVAF
LARHGVAPEEGVRAGVLAERQGRFVDRLRHRITFPIKDAFGRVVAFTGRALGEDGPKYLNTPETPLFRKQEVLFAYPEAR
PALREGRAIVVEGLFDAIALHQLGFPETVAVLGSGLSEGQALLLKKAGVLEVYLAFDADEAGQKATLQSLNLELAPRFLF
YAVRLPAKDPGELLLHPEGRALFQKALEEALPEVAFRFEEASRGLDLSRPEHKRKVLEALTPRMLTPEPFDPVAERLKAL
VVERLGLSPKSLEDYLASLRTRGRPAPPPPPPPPIPGNKTLLLELDAIALLLSAPEERFLELVDYVETQVWPPEGSFLGE
FLALARKEPRRDHLRRTLSQREEGGRLFERLLLAPRGEDPRLQEKLDHTLARLREAYLQERLAKVKAALAQNPDPPTLER
LLKEYQEIRVAIEAERRLYKRRPPPSGWST

Specific function: DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis [H]

COG id: COG0358

COG function: function code L; DNA primase (bacterial type)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Toprim domain [H]

Homologues:

Organism=Escherichia coli, GI1789447, Length=421, Percent_Identity=34.916864608076, Blast_Score=221, Evalue=1e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013264
- InterPro:   IPR006295
- InterPro:   IPR006171
- InterPro:   IPR002694 [H]

Pfam domain/function: PF01751 Toprim; PF08275 Toprim_N; PF01807 zf-CHC2 [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 66234; Mature: 66234

Theoretical pI: Translated: 8.67; Mature: 8.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAGQAVELIKSRLSLREVVSRYVALKPAGRGRWKGLCPFHQEKTPSFYVDEEKGLFYCF
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEE
GCKAGGDLFAFVQRAEGLDFPEALERLAEEAGVELPRRKAPERRRELLEVLALAQTYFLE
ECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
HLHAHPEALAYLRKRGLTEESVARFGLGYAPPKGDGLVAFLARHGVAPEEGVRAGVLAER
HHHCCHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHH
QGRFVDRLRHRITFPIKDAFGRVVAFTGRALGEDGPKYLNTPETPLFRKQEVLFAYPEAR
CCHHHHHHHHHCCCCHHHHHHHHHHHHCHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCC
PALREGRAIVVEGLFDAIALHQLGFPETVAVLGSGLSEGQALLLKKAGVLEVYLAFDADE
HHHHCCCEEEHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHCCEEEEEEEECCCC
AGQKATLQSLNLELAPRFLFYAVRLPAKDPGELLLHPEGRALFQKALEEALPEVAFRFEE
CCCHHHHHHHCHHHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHH
ASRGLDLSRPEHKRKVLEALTPRMLTPEPFDPVAERLKALVVERLGLSPKSLEDYLASLR
HHCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
TRGRPAPPPPPPPPIPGNKTLLLELDAIALLLSAPEERFLELVDYVETQVWPPEGSFLGE
HCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHH
FLALARKEPRRDHLRRTLSQREEGGRLFERLLLAPRGEDPRLQEKLDHTLARLREAYLQE
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
RLAKVKAALAQNPDPPTLERLLKEYQEIRVAIEAERRLYKRRPPPSGWST
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MDAGQAVELIKSRLSLREVVSRYVALKPAGRGRWKGLCPFHQEKTPSFYVDEEKGLFYCF
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEE
GCKAGGDLFAFVQRAEGLDFPEALERLAEEAGVELPRRKAPERRRELLEVLALAQTYFLE
ECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
HLHAHPEALAYLRKRGLTEESVARFGLGYAPPKGDGLVAFLARHGVAPEEGVRAGVLAER
HHHCCHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHH
QGRFVDRLRHRITFPIKDAFGRVVAFTGRALGEDGPKYLNTPETPLFRKQEVLFAYPEAR
CCHHHHHHHHHCCCCHHHHHHHHHHHHCHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCC
PALREGRAIVVEGLFDAIALHQLGFPETVAVLGSGLSEGQALLLKKAGVLEVYLAFDADE
HHHHCCCEEEHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHCCEEEEEEEECCCC
AGQKATLQSLNLELAPRFLFYAVRLPAKDPGELLLHPEGRALFQKALEEALPEVAFRFEE
CCCHHHHHHHCHHHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHH
ASRGLDLSRPEHKRKVLEALTPRMLTPEPFDPVAERLKALVVERLGLSPKSLEDYLASLR
HHCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
TRGRPAPPPPPPPPIPGNKTLLLELDAIALLLSAPEERFLELVDYVETQVWPPEGSFLGE
HCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHH
FLALARKEPRRDHLRRTLSQREEGGRLFERLLLAPRGEDPRLQEKLDHTLARLREAYLQE
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
RLAKVKAALAQNPDPPTLERLLKEYQEIRVAIEAERRLYKRRPPPSGWST
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring phosphorus-containing groups; Nucleotidyltransferases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]