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The map label for this gene is thyX [H]

Identifier: 55981065

GI number: 55981065

Start: 1042070

End: 1042882

Strand: Direct

Name: thyX [H]

Synonym: TTHA1096

Alternate gene names: 55981065

Gene position: 1042070-1042882 (Clockwise)

Preceding gene: 55981061

Following gene: 55981067

Centisome position: 56.34

GC content: 64.58

Gene sequence:

>813_bases
ATGGAAGGGCCTCTCACGATCCCGGTCTTGGACAAGGGCTTCGTCCGCCTGGTGGACCAGATGGGGGACGACCGCGCCAT
CGTCCAGGCGGCCCGGGTCTCCTACGGGGAAGGGACGAAGACGGTGCGGGAGGACGCCGCCCTCATTGACTACCTCATGC
GCCACCGCCACACGAGCCCCTTTGAGATGGTGGTCTTCAAGTTCCACGTCAAGGCCCCCATCTTCGTGGCGAGGCAGTGG
TTCCGCCACCGCACGGCGAGCGTCAACGAGATCTCGGGGCGCTACTCCATCCTCAAGGAGGAGTTCTACGAGCCCGAGGC
CTTCCGCAAGCAGGCGAAAAGAAACAAGCAGGCCTCGGAAGGGGCCCTCTTGGACGAGGAGGCCTTGGCCCTCCTAAGGA
AGGTGCAACAGGAGGCCTACGGGGCCTACCGGGCCCTTCTGGAGAAGGGCGTGGCCCGGGAGATGGCCCGGATGGTCCTT
CCCCTGAACCTCTACACCGAGTTCTACTGGAAGCAGGATCTGCACAACCTCTTCCACTTCCTCAAGCTCCGCCTCGCCCC
CGAGGCCCAGTGGGAGATCCGCCAGTACGCCCGGGCCATCGCCGAAATCGTCAAGGAAAGGGTCCCCCTCGCCTGGGCCG
CCTTTGAGGAACACCTCCTGGAAGGGGCCTTCCTCTCCCGCACGGAGCTTAGGGCCCTAAGGGGCCTCTTGACCCCTGAG
GTCTACGAGAAGGCCCTTTCCTCCTTGGGCCTTGGGGGAAGCCGCCTGAAGGAGGCCCTAGAGAAGGTCTTCGGGCCAGG
GGAAGCCCTTTAG

Upstream 100 bases:

>100_bases
GAAAGTCGGGTAGGGTCAGCATGCTTCGCTCCCTAAAGGCGCCTCGCGCCAAGACAACTCCCATCCTACCCCGGAGGGGC
CTCCCGGTAAACTCGGGGGG

Downstream 100 bases:

>100_bases
ACGAGCTCCTCCGCCTTCTTCCCCGTCCGCGCCTCCAGGAGCCGGTAGAGCTCCTCCTCCGTGAGGGTGGGGACCCCGAG
GGCCCTGGCCTTCTCCAGCT

Product: FAD-dependent thymidylate synthase

Products: NA

Alternate protein names: TS; TSase [H]

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MEGPLTIPVLDKGFVRLVDQMGDDRAIVQAARVSYGEGTKTVREDAALIDYLMRHRHTSPFEMVVFKFHVKAPIFVARQW
FRHRTASVNEISGRYSILKEEFYEPEAFRKQAKRNKQASEGALLDEEALALLRKVQQEAYGAYRALLEKGVAREMARMVL
PLNLYTEFYWKQDLHNLFHFLKLRLAPEAQWEIRQYARAIAEIVKERVPLAWAAFEEHLLEGAFLSRTELRALRGLLTPE
VYEKALSSLGLGGSRLKEALEKVFGPGEAL

Sequences:

>Translated_270_residues
MEGPLTIPVLDKGFVRLVDQMGDDRAIVQAARVSYGEGTKTVREDAALIDYLMRHRHTSPFEMVVFKFHVKAPIFVARQW
FRHRTASVNEISGRYSILKEEFYEPEAFRKQAKRNKQASEGALLDEEALALLRKVQQEAYGAYRALLEKGVAREMARMVL
PLNLYTEFYWKQDLHNLFHFLKLRLAPEAQWEIRQYARAIAEIVKERVPLAWAAFEEHLLEGAFLSRTELRALRGLLTPE
VYEKALSSLGLGGSRLKEALEKVFGPGEAL
>Mature_270_residues
MEGPLTIPVLDKGFVRLVDQMGDDRAIVQAARVSYGEGTKTVREDAALIDYLMRHRHTSPFEMVVFKFHVKAPIFVARQW
FRHRTASVNEISGRYSILKEEFYEPEAFRKQAKRNKQASEGALLDEEALALLRKVQQEAYGAYRALLEKGVAREMARMVL
PLNLYTEFYWKQDLHNLFHFLKLRLAPEAQWEIRQYARAIAEIVKERVPLAWAAFEEHLLEGAFLSRTELRALRGLLTPE
VYEKALSSLGLGGSRLKEALEKVFGPGEAL

Specific function: Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate [H]

COG id: COG1351

COG function: function code F; Predicted alternative thymidylate synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thyX (flavin-dependent thymidylate synthase) domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003669 [H]

Pfam domain/function: PF02511 Thy1 [H]

EC number: =2.1.1.148 [H]

Molecular weight: Translated: 31006; Mature: 31006

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGPLTIPVLDKGFVRLVDQMGDDRAIVQAARVSYGEGTKTVREDAALIDYLMRHRHTSP
CCCCCEECCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCC
FEMVVFKFHVKAPIFVARQWFRHRTASVNEISGRYSILKEEFYEPEAFRKQAKRNKQASE
HHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHC
GALLDEEALALLRKVQQEAYGAYRALLEKGVAREMARMVLPLNLYTEFYWKQDLHNLFHF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKLRLAPEAQWEIRQYARAIAEIVKERVPLAWAAFEEHLLEGAFLSRTELRALRGLLTPE
HHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
VYEKALSSLGLGGSRLKEALEKVFGPGEAL
HHHHHHHHCCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MEGPLTIPVLDKGFVRLVDQMGDDRAIVQAARVSYGEGTKTVREDAALIDYLMRHRHTSP
CCCCCEECCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCC
FEMVVFKFHVKAPIFVARQWFRHRTASVNEISGRYSILKEEFYEPEAFRKQAKRNKQASE
HHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHC
GALLDEEALALLRKVQQEAYGAYRALLEKGVAREMARMVLPLNLYTEFYWKQDLHNLFHF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKLRLAPEAQWEIRQYARAIAEIVKERVPLAWAAFEEHLLEGAFLSRTELRALRGLLTPE
HHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
VYEKALSSLGLGGSRLKEALEKVFGPGEAL
HHHHHHHHCCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA