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The map label for this gene is ruvC

Identifier: 55981059

GI number: 55981059

Start: 1037164

End: 1037664

Strand: Direct

Name: ruvC

Synonym: TTHA1090

Alternate gene names: 55981059

Gene position: 1037164-1037664 (Clockwise)

Preceding gene: 55981058

Following gene: 55981061

Centisome position: 56.07

GC content: 71.46

Gene sequence:

>501_bases
GTGGTCGTGGCCGGCATAGACCCCGGGATCACCCACCTGGGCCTCGGGGTGGTGGCGGTGGAGGGGAAGGGGGCCCTCAA
GGCCCGCCTCCTCCACGGGGAGGTGGTGAAGACCTCGCCGCAGGAGCCCGCAAAGGAGAGGGTGGGGCGGATCCACGCCC
GGGTCCTGGAGGTCCTCCACCGCTTCCGGCCCGAGGCGGTGGCGGTGGAGGAGCAGTTCTTCTACCGCCAAAACGAGCTC
GCCTACAAGGTGGGCTGGGCTCTGGGGGCCGTCCTGGTGGCGGCCTTTGAAGCGGGGGTGCCCGTCTACGCCTACGGCCC
CATGCAGGTGAAGCAGGCCCTGGCGGGGCACGGCCACGCCGCCAAGGAGGAGGTGGCCCTCATGGTCCGGGGCATCCTGG
GCCTGAAGGAGGCCCCGAGGCCAAGCCACCTGGCGGACGCCTTGGCCATCGCCCTGACCCACGCCTTCTACGCCCGCATG
GGCACGGCGAAGCCCCTTTAG

Upstream 100 bases:

>100_bases
ACGGGCCACGTGGACCTGACGAACTACGACATCCCCGCCTTCATCCGCTACGGGGACGGGGACTACCCGCCCAGGCGGGG
CAACTGAGCCTCCTCTTCCC

Downstream 100 bases:

>100_bases
ATCCCACCCCATGCTGGCTTGCGCCAGCATGGGGGCCCCGGCAAAAGGTCCTTAGGGAGCCTCCCCCGGCCCGTCGGACG
AAAGGGTATAGACGCCCTAA

Product: Holliday junction resolvase RuvC

Products: NA

Alternate protein names: Holliday junction nuclease ruvC; Holliday junction resolvase ruvC

Number of amino acids: Translated: 166; Mature: 166

Protein sequence:

>166_residues
MVVAGIDPGITHLGLGVVAVEGKGALKARLLHGEVVKTSPQEPAKERVGRIHARVLEVLHRFRPEAVAVEEQFFYRQNEL
AYKVGWALGAVLVAAFEAGVPVYAYGPMQVKQALAGHGHAAKEEVALMVRGILGLKEAPRPSHLADALAIALTHAFYARM
GTAKPL

Sequences:

>Translated_166_residues
MVVAGIDPGITHLGLGVVAVEGKGALKARLLHGEVVKTSPQEPAKERVGRIHARVLEVLHRFRPEAVAVEEQFFYRQNEL
AYKVGWALGAVLVAAFEAGVPVYAYGPMQVKQALAGHGHAAKEEVALMVRGILGLKEAPRPSHLADALAIALTHAFYARM
GTAKPL
>Mature_166_residues
MVVAGIDPGITHLGLGVVAVEGKGALKARLLHGEVVKTSPQEPAKERVGRIHARVLEVLHRFRPEAVAVEEQFFYRQNEL
AYKVGWALGAVLVAAFEAGVPVYAYGPMQVKQALAGHGHAAKEEVALMVRGILGLKEAPRPSHLADALAIALTHAFYARM
GTAKPL

Specific function: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leav

COG id: COG0817

COG function: function code L; Holliday junction resolvasome, endonuclease subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvC family

Homologues:

Organism=Escherichia coli, GI1788170, Length=139, Percent_Identity=33.8129496402878, Blast_Score=76, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVC_THET2 (Q72JP3)

Other databases:

- EMBL:   AE017221
- RefSeq:   YP_004700.1
- ProteinModelPortal:   Q72JP3
- SMR:   Q72JP3
- STRING:   Q72JP3
- GeneID:   2775794
- GenomeReviews:   AE017221_GR
- eggNOG:   COG0817
- HOGENOM:   HBG437552
- OMA:   RIAYQMT
- PhylomeDB:   Q72JP3
- ProtClustDB:   CLSK738600
- BioCyc:   TTHE262724:TT_C0725-MONOMER
- HAMAP:   MF_00034
- InterPro:   IPR012337
- InterPro:   IPR002176
- PRINTS:   PR00696
- TIGRFAMs:   TIGR00228

Pfam domain/function: PF02075 RuvC; SSF53098 RNaseH_fold

EC number: =3.1.22.4

Molecular weight: Translated: 17755; Mature: 17755

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: PS01321 RUVC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVAGIDPGITHLGLGVVAVEGKGALKARLLHGEVVKTSPQEPAKERVGRIHARVLEVLH
CEECCCCCCHHHHCCEEEEECCCCCHHHHHHHCHHHCCCCCCHHHHHHHHHHHHHHHHHH
RFRPEAVAVEEQFFYRQNELAYKVGWALGAVLVAAFEAGVPVYAYGPMQVKQALAGHGHA
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHCCCCC
AKEEVALMVRGILGLKEAPRPSHLADALAIALTHAFYARMGTAKPL
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MVVAGIDPGITHLGLGVVAVEGKGALKARLLHGEVVKTSPQEPAKERVGRIHARVLEVLH
CEECCCCCCHHHHCCEEEEECCCCCHHHHHHHCHHHCCCCCCHHHHHHHHHHHHHHHHHH
RFRPEAVAVEEQFFYRQNELAYKVGWALGAVLVAAFEAGVPVYAYGPMQVKQALAGHGHA
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHCCCCC
AKEEVALMVRGILGLKEAPRPSHLADALAIALTHAFYARMGTAKPL
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA