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The map label for this gene is mtnA [H]

Identifier: 55981041

GI number: 55981041

Start: 1021027

End: 1022019

Strand: Reverse

Name: mtnA [H]

Synonym: TTHA1072

Alternate gene names: 55981041

Gene position: 1022019-1021027 (Counterclockwise)

Preceding gene: 55981042

Following gene: 55981040

Centisome position: 55.25

GC content: 72.0

Gene sequence:

>993_bases
GTGGATCGGGTGCTTCCCTTTCGCTTCGCGGAGGAGGAGGGGGTCTTCTGGCTTTTGGACCAGAGGCGCCTGCCCCAGGA
GGAGGTCTACGTCCCGGTGCGCACCGCCCGGGAGATGGCCCAGGCCATCCGGGACATGGTGGTCCGGGGGGCGCCGGCCA
TCGGGGTCTCCGCCGCCTTCGGCATGGTCCTGGCCCACCTGGCGGGGGAGGACCTCGAGGAGGCGGACCGGAGGCTCAGG
GCGAGCCGCCCCACGGCGGTGAACCTCTTCCACGCCCTGGACCGGATGCGCCCCTTTTGGGGGGACCTGGCGGGAAGCCT
CCTCGAGGCGCGGCGCATCTGGCGGGAGGTGGAGGAAACGGAGGCGGCCATCAGCCGCCACGGCGCCCAGGTCCTCTGGG
GCCAGGTCCTCACCCACTGCAACACGGGTCCCCTGGCCACGGGCGGCTACGGCACCGCCCTCGGGGCCATCGTGGAGGCC
TACAGGCTTGGGCGGGTGCGGCACGTCTGGGTGGACGAGACCCGGCCCTACCTCCAAGGGGCCCGCCTGACCGCCTACGA
GCTCCAGAAGGCGGGGGTACCCGCCACCCTGATCACCGACGGCATGGCGGGCTGGCTCATGGCCCGGGGGGCCGTGGACG
CGGTGGTGGTGGGGGTGGACCGCATGGCCTTGAACGGGGACTTCGCCAACAAGGTGGGGACCTACGCCCTCGCCGTGCTG
GCCCACCACCACGGGATCCCCTTCTACGCCGCCTTGCCCCTTTCCTCCGTGGACCCCCGGTTGGCGAGCGGGGAGGGCAT
CCCCATAGAGGAGCGCTCCCCGGAGGAGGTGGTGGCCTTCCGCGGCGTGCGGATCGCCCCCGAGGGGTTTCCCGCCTACC
ACCCCGCCTTTGACGTGACCCCCCATCGGTACCTCACGGGGATCATCACGGAGAAGGGGGTCCTCTACCCCCCCTTCGCC
GAGGGGCTGCGGCGTGCCTTGGGGCTGGATTGA

Upstream 100 bases:

>100_bases
GCGGTTCCAGCGGCGCTACGGCGACTCTTACCGCAAGGGGCGCTAGGCCCTCTGGTCTAGGGCGGGGGATGGCCCCGCCC
GCTTTCCTTTAGGAGGCGGC

Downstream 100 bases:

>100_bases
AGCCTTGCTGGGCCACGCCTGCCCGGGGTGCGGGGGGCCCTTGGACCTTCCCGCCCTCTGCGGGCGTTGCCGGGCGGGCC
TCGAGGCCTTCTCCACGGGG

Product: translation initiation factor, aIF-2B subunit alpha-like protein

Products: NA

Alternate protein names: M1Pi; MTR-1-P isomerase; S-methyl-5-thioribose-1-phosphate isomerase [H]

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MDRVLPFRFAEEEGVFWLLDQRRLPQEEVYVPVRTAREMAQAIRDMVVRGAPAIGVSAAFGMVLAHLAGEDLEEADRRLR
ASRPTAVNLFHALDRMRPFWGDLAGSLLEARRIWREVEETEAAISRHGAQVLWGQVLTHCNTGPLATGGYGTALGAIVEA
YRLGRVRHVWVDETRPYLQGARLTAYELQKAGVPATLITDGMAGWLMARGAVDAVVVGVDRMALNGDFANKVGTYALAVL
AHHHGIPFYAALPLSSVDPRLASGEGIPIEERSPEEVVAFRGVRIAPEGFPAYHPAFDVTPHRYLTGIITEKGVLYPPFA
EGLRRALGLD

Sequences:

>Translated_330_residues
MDRVLPFRFAEEEGVFWLLDQRRLPQEEVYVPVRTAREMAQAIRDMVVRGAPAIGVSAAFGMVLAHLAGEDLEEADRRLR
ASRPTAVNLFHALDRMRPFWGDLAGSLLEARRIWREVEETEAAISRHGAQVLWGQVLTHCNTGPLATGGYGTALGAIVEA
YRLGRVRHVWVDETRPYLQGARLTAYELQKAGVPATLITDGMAGWLMARGAVDAVVVGVDRMALNGDFANKVGTYALAVL
AHHHGIPFYAALPLSSVDPRLASGEGIPIEERSPEEVVAFRGVRIAPEGFPAYHPAFDVTPHRYLTGIITEKGVLYPPFA
EGLRRALGLD
>Mature_330_residues
MDRVLPFRFAEEEGVFWLLDQRRLPQEEVYVPVRTAREMAQAIRDMVVRGAPAIGVSAAFGMVLAHLAGEDLEEADRRLR
ASRPTAVNLFHALDRMRPFWGDLAGSLLEARRIWREVEETEAAISRHGAQVLWGQVLTHCNTGPLATGGYGTALGAIVEA
YRLGRVRHVWVDETRPYLQGARLTAYELQKAGVPATLITDGMAGWLMARGAVDAVVVGVDRMALNGDFANKVGTYALAVL
AHHHGIPFYAALPLSSVDPRLASGEGIPIEERSPEEVVAFRGVRIAPEGFPAYHPAFDVTPHRYLTGIITEKGVLYPPFA
EGLRRALGLD

Specific function: Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) [H]

COG id: COG0182

COG function: function code J; Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily [H]

Homologues:

Organism=Homo sapiens, GI72534748, Length=347, Percent_Identity=45.2449567723343, Blast_Score=232, Evalue=3e-61,
Organism=Homo sapiens, GI23943880, Length=327, Percent_Identity=42.8134556574924, Blast_Score=185, Evalue=6e-47,
Organism=Homo sapiens, GI7657058, Length=222, Percent_Identity=27.9279279279279, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17557462, Length=323, Percent_Identity=40.5572755417957, Blast_Score=219, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI17557123, Length=218, Percent_Identity=30.2752293577982, Blast_Score=84, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6325375, Length=393, Percent_Identity=33.3333333333333, Blast_Score=182, Evalue=5e-47,
Organism=Saccharomyces cerevisiae, GI6322878, Length=180, Percent_Identity=35, Blast_Score=79, Evalue=9e-16,
Organism=Drosophila melanogaster, GI21357667, Length=344, Percent_Identity=42.4418604651163, Blast_Score=234, Evalue=6e-62,
Organism=Drosophila melanogaster, GI24651647, Length=344, Percent_Identity=42.4418604651163, Blast_Score=234, Evalue=6e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000649
- InterPro:   IPR005251
- InterPro:   IPR011559 [H]

Pfam domain/function: PF01008 IF-2B [H]

EC number: =5.3.1.23 [H]

Molecular weight: Translated: 36206; Mature: 36206

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRVLPFRFAEEEGVFWLLDQRRLPQEEVYVPVRTAREMAQAIRDMVVRGAPAIGVSAAF
CCCCCCCEEECCCCEEEEECCCCCCHHHEEECHHHHHHHHHHHHHHHHHCCCCHHHHHHH
GMVLAHLAGEDLEEADRRLRASRPTAVNLFHALDRMRPFWGDLAGSLLEARRIWREVEET
HHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
EAAISRHGAQVLWGQVLTHCNTGPLATGGYGTALGAIVEAYRLGRVRHVWVDETRPYLQG
HHHHHHCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCHHHCC
ARLTAYELQKAGVPATLITDGMAGWLMARGAVDAVVVGVDRMALNGDFANKVGTYALAVL
CCCHHHHHHHCCCCHHHHHCCHHHHHHHHCCHHEEEEEHHHHEECCCHHHHHHHHHHHHH
AHHHGIPFYAALPLSSVDPRLASGEGIPIEERSPEEVVAFRGVRIAPEGFPAYHPAFDVT
HHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCEECCCCCCCCCCCCCCC
PHRYLTGIITEKGVLYPPFAEGLRRALGLD
HHHHHHHHHHCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MDRVLPFRFAEEEGVFWLLDQRRLPQEEVYVPVRTAREMAQAIRDMVVRGAPAIGVSAAF
CCCCCCCEEECCCCEEEEECCCCCCHHHEEECHHHHHHHHHHHHHHHHHCCCCHHHHHHH
GMVLAHLAGEDLEEADRRLRASRPTAVNLFHALDRMRPFWGDLAGSLLEARRIWREVEET
HHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
EAAISRHGAQVLWGQVLTHCNTGPLATGGYGTALGAIVEAYRLGRVRHVWVDETRPYLQG
HHHHHHCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCHHHCC
ARLTAYELQKAGVPATLITDGMAGWLMARGAVDAVVVGVDRMALNGDFANKVGTYALAVL
CCCHHHHHHHCCCCHHHHHCCHHHHHHHHCCHHEEEEEHHHHEECCCHHHHHHHHHHHHH
AHHHGIPFYAALPLSSVDPRLASGEGIPIEERSPEEVVAFRGVRIAPEGFPAYHPAFDVT
HHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCEECCCCCCCCCCCCCCC
PHRYLTGIITEKGVLYPPFAEGLRRALGLD
HHHHHHHHHHCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA