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The map label for this gene is yqhT [H]

Identifier: 55981037

GI number: 55981037

Start: 1017248

End: 1018282

Strand: Direct

Name: yqhT [H]

Synonym: TTHA1068

Alternate gene names: 55981037

Gene position: 1017248-1018282 (Clockwise)

Preceding gene: 55981036

Following gene: 55981038

Centisome position: 54.99

GC content: 71.5

Gene sequence:

>1035_bases
GTGCTGCCGAAGGACCTCCTAGAGCCCCTCGGGCTTGACGCCCTCCTCGTCACCCGGCCGGAGAACGTCCGCTACCTTTC
GGGCTTCCCCCACCCCGAGGACGCCCAGGTCCTGGTCACGGGGGAAGGGGCCTTCCTCCTCACCGACCCCCGCTACCCGG
AGGCCGAAAGGGAAAGCCGCATCCCCGCCAAGGTCCTCAAGCGGGAAGAGCGGGAGGCCCTCCTCAAGACCCTGAAGGGC
CGGGTGGGCTTTGAGGCCGAGCACCTCCCCTACGCCGCCCTGGAGCGCCTGAGGGAGCTCGTCCCCGCCGAGTGGGTGCC
CACCAAGGGGGTGGTGGAAAAGCTCCGGCTCCGCAAAACCCCGGAGGAGGTGGAAAGGATCCGCAAGGCCCAGGCCCTGG
CGGAGGAGGCCCTGGCCCACGTCCTCCCCCTCCTCAGGCCCGGGGTGGAGGAGCGGGAGATCGCCCTGGAGGTGGAGTTC
TTCCTCAAAAGGCGGGGGGCCGAAGGGGCGGCCTTCCCCCCCATCGTGGCCTCCGGGGAGCGGGGGGCCCTGCCCCACGC
GCGGGCCTCGGAGAAGCGCCTAAAGGCAGGGGAGCTCGTCACCCTGGACCTCGGGGCGCGGCTTGAGGGGTACCACTCGG
ACATGACCCGCACCTTCGCCCTCGGCAGGCCCAAGGAGGAGCTCCGCCGGGCCTACAAGGCGGTGGAGGAGGCCCTGGAG
GCGGCCCTCGCCGCCTTGGCCCCCGGGAAGACGGGCAAGGAGGTGGACGCGGTGGCCCGAAAAGCGCTGGAGGCCCACGG
GCTGGACCGCTACTTCGTCCACTCCCTGGGCCACGGGGTGGGCCTCGCCGTTCACGAGGGGCCGAGCCTCTCCCCCTACG
GCGAGGAGGTCCTGGAGCCCGGCATGGTGGTGACGGTGGAGCCCGGGGTCTACCTGCCGGGGCTTGGGGGCGTGCGGCTT
GAGGAGCTCGTCCTCCTCACCGAAAGCGGCGTGGAGCTCCTCTCCCGCTTTCCCCGGGACTTTCAGGAGCTCTAA

Upstream 100 bases:

>100_bases
CGGAGTGAACCCACCCCACGCGGGCTTGCGCCAGCGTGGGGACCCCGCAAAGGCCTCCCTAGGCTTTACCGGGGGGAGGA
GCCTTGGGTATAGTGCCCCC

Downstream 100 bases:

>100_bases
TGCAAAGCCCGTAAGATGGGGGCGTGTACGCCATCCGCGAGGGGCTAAAGCAGGTTTTCCGCCACCCCACGGCAAGCCTC
GCCACCTTCTTCACCGCCCT

Product: proline dipeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MLPKDLLEPLGLDALLVTRPENVRYLSGFPHPEDAQVLVTGEGAFLLTDPRYPEAERESRIPAKVLKREEREALLKTLKG
RVGFEAEHLPYAALERLRELVPAEWVPTKGVVEKLRLRKTPEEVERIRKAQALAEEALAHVLPLLRPGVEEREIALEVEF
FLKRRGAEGAAFPPIVASGERGALPHARASEKRLKAGELVTLDLGARLEGYHSDMTRTFALGRPKEELRRAYKAVEEALE
AALAALAPGKTGKEVDAVARKALEAHGLDRYFVHSLGHGVGLAVHEGPSLSPYGEEVLEPGMVVTVEPGVYLPGLGGVRL
EELVLLTESGVELLSRFPRDFQEL

Sequences:

>Translated_344_residues
MLPKDLLEPLGLDALLVTRPENVRYLSGFPHPEDAQVLVTGEGAFLLTDPRYPEAERESRIPAKVLKREEREALLKTLKG
RVGFEAEHLPYAALERLRELVPAEWVPTKGVVEKLRLRKTPEEVERIRKAQALAEEALAHVLPLLRPGVEEREIALEVEF
FLKRRGAEGAAFPPIVASGERGALPHARASEKRLKAGELVTLDLGARLEGYHSDMTRTFALGRPKEELRRAYKAVEEALE
AALAALAPGKTGKEVDAVARKALEAHGLDRYFVHSLGHGVGLAVHEGPSLSPYGEEVLEPGMVVTVEPGVYLPGLGGVRL
EELVLLTESGVELLSRFPRDFQEL
>Mature_344_residues
MLPKDLLEPLGLDALLVTRPENVRYLSGFPHPEDAQVLVTGEGAFLLTDPRYPEAERESRIPAKVLKREEREALLKTLKG
RVGFEAEHLPYAALERLRELVPAEWVPTKGVVEKLRLRKTPEEVERIRKAQALAEEALAHVLPLLRPGVEEREIALEVEF
FLKRRGAEGAAFPPIVASGERGALPHARASEKRLKAGELVTLDLGARLEGYHSDMTRTFALGRPKEELRRAYKAVEEALE
AALAALAPGKTGKEVDAVARKALEAHGLDRYFVHSLGHGVGLAVHEGPSLSPYGEEVLEPGMVVTVEPGVYLPGLGGVRL
EELVLLTESGVELLSRFPRDFQEL

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI11559925, Length=269, Percent_Identity=31.2267657992565, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI264681563, Length=224, Percent_Identity=35.2678571428571, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI149589008, Length=299, Percent_Identity=26.0869565217391, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI260593665, Length=299, Percent_Identity=26.0869565217391, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI264681565, Length=221, Percent_Identity=33.4841628959276, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI164420681, Length=244, Percent_Identity=25.4098360655738, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI93141226, Length=189, Percent_Identity=31.7460317460317, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1788728, Length=354, Percent_Identity=39.8305084745763, Blast_Score=235, Evalue=3e-63,
Organism=Escherichia coli, GI1789275, Length=288, Percent_Identity=32.9861111111111, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1786364, Length=203, Percent_Identity=31.0344827586207, Blast_Score=95, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI71989583, Length=267, Percent_Identity=26.9662921348315, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17508215, Length=294, Percent_Identity=27.2108843537415, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71996291, Length=246, Percent_Identity=26.0162601626016, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17509539, Length=173, Percent_Identity=34.1040462427746, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6321118, Length=307, Percent_Identity=25.0814332247557, Blast_Score=91, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6323273, Length=254, Percent_Identity=28.740157480315, Blast_Score=89, Evalue=8e-19,
Organism=Saccharomyces cerevisiae, GI6320922, Length=253, Percent_Identity=23.3201581027668, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6322999, Length=241, Percent_Identity=29.045643153527, Blast_Score=77, Evalue=3e-15,
Organism=Drosophila melanogaster, GI19920384, Length=277, Percent_Identity=30.3249097472924, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI21357079, Length=298, Percent_Identity=26.1744966442953, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24583427, Length=187, Percent_Identity=25.1336898395722, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI21355531, Length=244, Percent_Identity=24.5901639344262, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI17137632, Length=165, Percent_Identity=33.3333333333333, Blast_Score=75, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 37895; Mature: 37895

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS00491 PROLINE_PEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPKDLLEPLGLDALLVTRPENVRYLSGFPHPEDAQVLVTGEGAFLLTDPRYPEAERESR
CCCHHHHHHCCCCEEEEECCCCCEEECCCCCCCCCEEEEECCCEEEEECCCCCCHHHHCC
IPAKVLKREEREALLKTLKGRVGFEAEHLPYAALERLRELVPAEWVPTKGVVEKLRLRKT
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCC
PEEVERIRKAQALAEEALAHVLPLLRPGVEEREIALEVEFFLKRRGAEGAAFPPIVASGE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEECCC
RGALPHARASEKRLKAGELVTLDLGARLEGYHSDMTRTFALGRPKEELRRAYKAVEEALE
CCCCCCCCCHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
AALAALAPGKTGKEVDAVARKALEAHGLDRYFVHSLGHGVGLAVHEGPSLSPYGEEVLEP
HHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEEEECCCCCCCCCHHHHCC
GMVVTVEPGVYLPGLGGVRLEELVLLTESGVELLSRFPRDFQEL
CEEEEECCCEEECCCCCCCHHHHHHHHHHHHHHHHHCCHHHHCC
>Mature Secondary Structure
MLPKDLLEPLGLDALLVTRPENVRYLSGFPHPEDAQVLVTGEGAFLLTDPRYPEAERESR
CCCHHHHHHCCCCEEEEECCCCCEEECCCCCCCCCEEEEECCCEEEEECCCCCCHHHHCC
IPAKVLKREEREALLKTLKGRVGFEAEHLPYAALERLRELVPAEWVPTKGVVEKLRLRKT
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCC
PEEVERIRKAQALAEEALAHVLPLLRPGVEEREIALEVEFFLKRRGAEGAAFPPIVASGE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEECCC
RGALPHARASEKRLKAGELVTLDLGARLEGYHSDMTRTFALGRPKEELRRAYKAVEEALE
CCCCCCCCCHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
AALAALAPGKTGKEVDAVARKALEAHGLDRYFVHSLGHGVGLAVHEGPSLSPYGEEVLEP
HHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEEEECCCCCCCCCHHHHCC
GMVVTVEPGVYLPGLGGVRLEELVLLTESGVELLSRFPRDFQEL
CEEEEECCCEEECCCCCCCHHHHHHHHHHHHHHHHHCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]