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The map label for this gene is ftsX [H]

Identifier: 55981038

GI number: 55981038

Start: 1018306

End: 1019160

Strand: Direct

Name: ftsX [H]

Synonym: TTHA1069

Alternate gene names: 55981038

Gene position: 1018306-1019160 (Clockwise)

Preceding gene: 55981037

Following gene: 55981039

Centisome position: 55.05

GC content: 70.29

Gene sequence:

>855_bases
GTGTACGCCATCCGCGAGGGGCTAAAGCAGGTTTTCCGCCACCCCACGGCAAGCCTCGCCACCTTCTTCACCGCCCTGGT
CTCCTTCACCCTGCTCTACTTCCTGGGGCTCCTCCTCTGGAACCTGGAGCGGGTGGTCCAGACCATGGAGCGGGAGCTGG
AGGTGGCCGCCTTCCTCGGCCCCAAGGCGGACGTGGAAGGCCTTCTCGCCGAGATCCAAAAGTGGCCCGAGGTGGCCTCC
GCCCGGCTCCAGACCAAGGAGGAGGCCCTGGCCCAGCTGGTCCTGGACTACCCCTACCTGGCGGAGGCCAAGGACCTGGT
GGAAAACCCCCTGCCCGACACCCTGCGCCTGCGGCTTAGGGAACCCGAGGCGGTGCGGCGGGTGGCGGAGCGCCTCGCCC
GCCTCCCCGGGGTGGAAGGGGTGGAGTACGGGGGAGAGATCACGGAAAGGCTCGTCCAGCTCCTCCAGGGCAGCCGCGTG
GCCATGCTGGTCCTCGTGGGGCTTCTCCTCCTCAACACCTTCTTCAGCGTCATGGGCTCCATCCGCCTCTCGGTGGAGAG
CCGGCGGGAGGCCCTGGGCATCATGCTCCTCGTGGGCGCCACCCGGCGGTTCATCCAGGCCCCCTTCGTCGTGGAGGGAA
CGTTCCTCACCTTGGGAGCGGGGCTTCTCGCCGTGGCCGTGGGGGCCTTCCTCTACCGGGCCCTGGCCCAGGCGGTCCAG
ACCCTCCTGCCCTTCGTCCCCGTCCTCTCCCCCGAGGACCTGGGGCGGACGGCGGGCCTCGTCCTCCTCCTGGCCCTCGT
CCTGGGCGCAGGCGGGGCTTTCGCCGCAAGCCGGGCCCACCTGCGGGAGGTGTGA

Upstream 100 bases:

>100_bases
TTGAGGAGCTCGTCCTCCTCACCGAAAGCGGCGTGGAGCTCCTCTCCCGCTTTCCCCGGGACTTTCAGGAGCTCTAATGC
AAAGCCCGTAAGATGGGGGC

Downstream 100 bases:

>100_bases
GGTGGGCCGCCTCCTCCTCCTTGTCCTCCTCCTCCTTGCCCCCGCCTGGAGCCAGGACCTCGCGGCCCAGGAAAAGCGCG
TCCAGGATCTGGAGGCCCAG

Product: cell division protein FtsX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MYAIREGLKQVFRHPTASLATFFTALVSFTLLYFLGLLLWNLERVVQTMERELEVAAFLGPKADVEGLLAEIQKWPEVAS
ARLQTKEEALAQLVLDYPYLAEAKDLVENPLPDTLRLRLREPEAVRRVAERLARLPGVEGVEYGGEITERLVQLLQGSRV
AMLVLVGLLLLNTFFSVMGSIRLSVESRREALGIMLLVGATRRFIQAPFVVEGTFLTLGAGLLAVAVGAFLYRALAQAVQ
TLLPFVPVLSPEDLGRTAGLVLLLALVLGAGGAFAASRAHLREV

Sequences:

>Translated_284_residues
MYAIREGLKQVFRHPTASLATFFTALVSFTLLYFLGLLLWNLERVVQTMERELEVAAFLGPKADVEGLLAEIQKWPEVAS
ARLQTKEEALAQLVLDYPYLAEAKDLVENPLPDTLRLRLREPEAVRRVAERLARLPGVEGVEYGGEITERLVQLLQGSRV
AMLVLVGLLLLNTFFSVMGSIRLSVESRREALGIMLLVGATRRFIQAPFVVEGTFLTLGAGLLAVAVGAFLYRALAQAVQ
TLLPFVPVLSPEDLGRTAGLVLLLALVLGAGGAFAASRAHLREV
>Mature_284_residues
MYAIREGLKQVFRHPTASLATFFTALVSFTLLYFLGLLLWNLERVVQTMERELEVAAFLGPKADVEGLLAEIQKWPEVAS
ARLQTKEEALAQLVLDYPYLAEAKDLVENPLPDTLRLRLREPEAVRRVAERLARLPGVEGVEYGGEITERLVQLLQGSRV
AMLVLVGLLLLNTFFSVMGSIRLSVESRREALGIMLLVGATRRFIQAPFVVEGTFLTLGAGLLAVAVGAFLYRALAQAVQ
TLLPFVPVLSPEDLGRTAGLVLLLALVLGAGGAFAASRAHLREV

Specific function: Part of the ABC transporter ftsEX involved in sporulation. May act as an importer, possibly at the top of a hierarchical cascade leading to the correct temporal initiation of sporulation. Acts upstream of the histidine kinases KinA, KinB and KInC, the Rap

COG id: COG2177

COG function: function code D; Cell division protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable). Note=Unlike the E.coli ortholog, localization is not restricted to division septa, nor is it dependent on ftsZ [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789872, Length=226, Percent_Identity=26.1061946902655, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 31076; Mature: 31076

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYAIREGLKQVFRHPTASLATFFTALVSFTLLYFLGLLLWNLERVVQTMERELEVAAFLG
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PKADVEGLLAEIQKWPEVASARLQTKEEALAQLVLDYPYLAEAKDLVENPLPDTLRLRLR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHCC
EPEAVRRVAERLARLPGVEGVEYGGEITERLVQLLQGSRVAMLVLVGLLLLNTFFSVMGS
CCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
IRLSVESRREALGIMLLVGATRRFIQAPFVVEGTFLTLGAGLLAVAVGAFLYRALAQAVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLLPFVPVLSPEDLGRTAGLVLLLALVLGAGGAFAASRAHLREV
HHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MYAIREGLKQVFRHPTASLATFFTALVSFTLLYFLGLLLWNLERVVQTMERELEVAAFLG
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PKADVEGLLAEIQKWPEVASARLQTKEEALAQLVLDYPYLAEAKDLVENPLPDTLRLRLR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHCC
EPEAVRRVAERLARLPGVEGVEYGGEITERLVQLLQGSRVAMLVLVGLLLLNTFFSVMGS
CCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
IRLSVESRREALGIMLLVGATRRFIQAPFVVEGTFLTLGAGLLAVAVGAFLYRALAQAVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLLPFVPVLSPEDLGRTAGLVLLLALVLGAGGAFAASRAHLREV
HHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]