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The map label for this gene is kstR2 [H]

Identifier: 55980942

GI number: 55980942

Start: 916774

End: 917385

Strand: Reverse

Name: kstR2 [H]

Synonym: TTHA0973

Alternate gene names: 55980942

Gene position: 917385-916774 (Counterclockwise)

Preceding gene: 55980943

Following gene: 55980941

Centisome position: 49.6

GC content: 68.63

Gene sequence:

>612_bases
ATGGACCGCCGGAGCCAGATCCTCACCATCGCCGGGCACCTCTTCAGCCAGAGGGGCTACCACGCCACCAGCATGCGGGA
GCTCGCCCGCCACCTGAACCTCCAGGGCGGGAGCCTCTACGCCCACATCCAGTCCAAGGAGGAGCTCCTCCTGGAGGTGG
TGCGCCAGGCGGCGGAGAGGTTCCAGAAGGTCTTGGAGGAGCTTCCTTCGGGAGACCCCGTGACCCGGATGAAGGCCCTC
GTCAAGGGCCACCTCCGGGTCATCGCCGAGGAGCTTCCCCGGGCCACGGTCTTCTTCCACGAGTGGAAGCACCTCTCCCC
TCCCCTCCTCGAGGAGGCCAAGGCCCTGAGGCGCCGCTACGAGGAGGGGGTGCAGGCCGTGGTGGAGGAGGGGGTGCGGG
CGGGGGTCTTCCGGGTGGAGAACGTGCGGCTCGCCACCCTCTTCGTCCTCTCCGCCCTCAACTGGACCTACCAGTGGTAC
CGGCCCGACGGCCCCCTCTCCCTGGAAGCGCTCGCAGAGGCCTACGCCGAGCTGGTCCTCAAGGCCCTTGGCGTGGCGGC
TTCCCCGGAAGGGGAACGCCGTGAGGAAGGAGGCGAAGATGGTGAAGCTTAG

Upstream 100 bases:

>100_bases
GCCCCAAGCGGGCTTGGGCCGGCGTGGAGGTTCCGCCAGGGTGGCGGGGACACTTGACCCTTCGCCCAGGTTGTGCGAAA
CTAACAAACGACCGTTAGCC

Downstream 100 bases:

>100_bases
GATCGGCTACCCCGAGGACCCCGACTACCAGGAAAGGCTAGAAGAGTTTGAGGCCCGGATCGCCCGCGGGGAGAAGATTG
AGCCCGGGGACTGGATGCCC

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MDRRSQILTIAGHLFSQRGYHATSMRELARHLNLQGGSLYAHIQSKEELLLEVVRQAAERFQKVLEELPSGDPVTRMKAL
VKGHLRVIAEELPRATVFFHEWKHLSPPLLEEAKALRRRYEEGVQAVVEEGVRAGVFRVENVRLATLFVLSALNWTYQWY
RPDGPLSLEALAEAYAELVLKALGVAASPEGERREEGGEDGEA

Sequences:

>Translated_203_residues
MDRRSQILTIAGHLFSQRGYHATSMRELARHLNLQGGSLYAHIQSKEELLLEVVRQAAERFQKVLEELPSGDPVTRMKAL
VKGHLRVIAEELPRATVFFHEWKHLSPPLLEEAKALRRRYEEGVQAVVEEGVRAGVFRVENVRLATLFVLSALNWTYQWY
RPDGPLSLEALAEAYAELVLKALGVAASPEGERREEGGEDGEA
>Mature_203_residues
MDRRSQILTIAGHLFSQRGYHATSMRELARHLNLQGGSLYAHIQSKEELLLEVVRQAAERFQKVLEELPSGDPVTRMKAL
VKGHLRVIAEELPRATVFFHEWKHLSPPLLEEAKALRRRYEEGVQAVVEEGVRAGVFRVENVRLATLFVLSALNWTYQWY
RPDGPLSLEALAEAYAELVLKALGVAASPEGERREEGGEDGEA

Specific function: Controls the expression of a small regulon that may play a role in the utilization of cholesterol [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 22893; Mature: 22893

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRRSQILTIAGHLFSQRGYHATSMRELARHLNLQGGSLYAHIQSKEELLLEVVRQAAER
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHH
FQKVLEELPSGDPVTRMKALVKGHLRVIAEELPRATVFFHEWKHLSPPLLEEAKALRRRY
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHH
EEGVQAVVEEGVRAGVFRVENVRLATLFVLSALNWTYQWYRPDGPLSLEALAEAYAELVL
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCEEEECCCCCCCHHHHHHHHHHHHH
KALGVAASPEGERREEGGEDGEA
HHHCCCCCCCCCHHHCCCCCCCC
>Mature Secondary Structure
MDRRSQILTIAGHLFSQRGYHATSMRELARHLNLQGGSLYAHIQSKEELLLEVVRQAAER
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHH
FQKVLEELPSGDPVTRMKALVKGHLRVIAEELPRATVFFHEWKHLSPPLLEEAKALRRRY
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHH
EEGVQAVVEEGVRAGVFRVENVRLATLFVLSALNWTYQWYRPDGPLSLEALAEAYAELVL
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCEEEECCCCCCCHHHHHHHHHHHHH
KALGVAASPEGERREEGGEDGEA
HHHCCCCCCCCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA