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The map label for this gene is purN [H]

Identifier: 55980780

GI number: 55980780

Start: 773980

End: 774834

Strand: Direct

Name: purN [H]

Synonym: TTHA0811

Alternate gene names: 55980780

Gene position: 773980-774834 (Clockwise)

Preceding gene: 55980779

Following gene: 55980781

Centisome position: 41.84

GC content: 74.15

Gene sequence:

>855_bases
ATGGCCGTCTTCGCCTCCGGGAGGGGGACGAACCTCGAGGCCCTCCTCCAGGCCTTCCCCAAAGGGCACCCCTTGGGGGA
GGTGGTCCTGGTGGTCTCCGACAACCCCGAGGCCCTGGCCCTGGAGCGGGCAAGGAGGCGGGGGGTAGAGGCCCTGGCCC
TCCCCTGGCGGGGGCGGCGGGCCTTTGAGGAGGAGGCCTTGGGGCTTTTGGCGGCGAGGGGGGTGGACCTCGTCCTCCTC
GCGGGCTTCATGCGCCTCCTCTCCCCCCGGTTCGTGGAGCCCTGGTACGGCCGCCTCCTCAACGTCCACCCCTCCCTCCT
CCCCGACTACCCGGGGCTTCACGTCCACCGCCGGGTCCTGGAGGCGGGGGAGAGGGAGACGGGCTCCACCGTCCACTTCG
TGGACCAGGGGATGGACACGGGGCCCATCCTCCTCCAGGGGCGGGTGCCCGTCCTTCCGGGGGACACGCCGGAGGCCTTG
GAGGCCCGCGTCCTCCGCCTGGAGCATAGGCTTTACCCCAAGGCCGTCCGCCTCCTCCTCCGGGGGCTCGCCTTCCCCCC
GCCCCCGGACCTCGAGGCCCGGCTTGGGCGGGAGGCGGCGGGGGCCTTCCTGGCCCTCTCCCCGCGGGAAAAGCCCCTGT
ACCTCAGGGCCTGGGCCCTCCTTCGCGCTTGGGGGCAGGAGGCGCTGGTGGGCCCCGCCTTCCTGGGGCAAGGGGGGGAG
TGGGGGCGGGGCGCCTTCCTCGCCGCCCACCTCCTCGCCGAGCCCAGCCCCGTCCTCCTGGAGGAGGTGGCGGGGCTTCC
CGGGGAGGTCCGGGCCCGGGTGGAGGAGGCGTTGCGGGTAGAATCCTCACCATGA

Upstream 100 bases:

>100_bases
CTTCATGAACCTCCAGGGCCTCGTGCGCTACTGGCGGAAGCACCACCCGGAGGCCTTGGAGGGTTAGGTGACGCCCTTTC
CCTTGGGGCGGCCCGCCCGG

Downstream 100 bases:

>100_bases
AGGTCCTCGTGGTGGGCAGCGGGGGGCGGGAGCACGCCCTCCTTTGGAAGGCGGCCCAAAGCCCAAGGGTGAAGCGGCTT
TACGCCGCCCCCGGAAACGC

Product: phosphoribosylglycinamide formyltransferase PurD

Products: NA

Alternate protein names: 5'-phosphoribosylglycinamide transformylase; GAR transformylase; GART [H]

Number of amino acids: Translated: 284; Mature: 283

Protein sequence:

>284_residues
MAVFASGRGTNLEALLQAFPKGHPLGEVVLVVSDNPEALALERARRRGVEALALPWRGRRAFEEEALGLLAARGVDLVLL
AGFMRLLSPRFVEPWYGRLLNVHPSLLPDYPGLHVHRRVLEAGERETGSTVHFVDQGMDTGPILLQGRVPVLPGDTPEAL
EARVLRLEHRLYPKAVRLLLRGLAFPPPPDLEARLGREAAGAFLALSPREKPLYLRAWALLRAWGQEALVGPAFLGQGGE
WGRGAFLAAHLLAEPSPVLLEEVAGLPGEVRARVEEALRVESSP

Sequences:

>Translated_284_residues
MAVFASGRGTNLEALLQAFPKGHPLGEVVLVVSDNPEALALERARRRGVEALALPWRGRRAFEEEALGLLAARGVDLVLL
AGFMRLLSPRFVEPWYGRLLNVHPSLLPDYPGLHVHRRVLEAGERETGSTVHFVDQGMDTGPILLQGRVPVLPGDTPEAL
EARVLRLEHRLYPKAVRLLLRGLAFPPPPDLEARLGREAAGAFLALSPREKPLYLRAWALLRAWGQEALVGPAFLGQGGE
WGRGAFLAAHLLAEPSPVLLEEVAGLPGEVRARVEEALRVESSP
>Mature_283_residues
AVFASGRGTNLEALLQAFPKGHPLGEVVLVVSDNPEALALERARRRGVEALALPWRGRRAFEEEALGLLAARGVDLVLLA
GFMRLLSPRFVEPWYGRLLNVHPSLLPDYPGLHVHRRVLEAGERETGSTVHFVDQGMDTGPILLQGRVPVLPGDTPEALE
ARVLRLEHRLYPKAVRLLLRGLAFPPPPDLEARLGREAAGAFLALSPREKPLYLRAWALLRAWGQEALVGPAFLGQGGEW
GRGAFLAAHLLAEPSPVLLEEVAGLPGEVRARVEEALRVESSP

Specific function: De novo purine biosynthesis; third step. [C]

COG id: COG0299

COG function: function code F; Folate-dependent phosphoribosylglycinamide formyltransferase PurN

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GART family [H]

Homologues:

Organism=Homo sapiens, GI4503915, Length=185, Percent_Identity=38.9189189189189, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI209869995, Length=185, Percent_Identity=38.9189189189189, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI209869993, Length=185, Percent_Identity=38.9189189189189, Blast_Score=144, Evalue=1e-34,
Organism=Escherichia coli, GI1788846, Length=185, Percent_Identity=43.7837837837838, Blast_Score=165, Evalue=3e-42,
Organism=Escherichia coli, GI1787483, Length=122, Percent_Identity=29.5081967213115, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17567511, Length=177, Percent_Identity=36.1581920903955, Blast_Score=110, Evalue=9e-25,
Organism=Drosophila melanogaster, GI24582400, Length=193, Percent_Identity=46.1139896373057, Blast_Score=175, Evalue=3e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002376
- InterPro:   IPR001555
- InterPro:   IPR004607 [H]

Pfam domain/function: PF00551 Formyl_trans_N [H]

EC number: =2.1.2.2 [H]

Molecular weight: Translated: 30966; Mature: 30835

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVFASGRGTNLEALLQAFPKGHPLGEVVLVVSDNPEALALERARRRGVEALALPWRGRR
CEEECCCCCCCHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCEEEECCCCCCH
AFEEEALGLLAARGVDLVLLAGFMRLLSPRFVEPWYGRLLNVHPSLLPDYPGLHVHRRVL
HHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHCCCCCCHHHHHHHH
EAGERETGSTVHFVDQGMDTGPILLQGRVPVLPGDTPEALEARVLRLEHRLYPKAVRLLL
HCCCCCCCCEEEEECCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHH
RGLAFPPPPDLEARLGREAAGAFLALSPREKPLYLRAWALLRAWGQEALVGPAFLGQGGE
HHCCCCCCCCHHHHHCHHHHCEEEEECCCCCCHHHHHHHHHHHHCHHHHCCHHHHCCCCC
WGRGAFLAAHLLAEPSPVLLEEVAGLPGEVRARVEEALRVESSP
CCCHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AVFASGRGTNLEALLQAFPKGHPLGEVVLVVSDNPEALALERARRRGVEALALPWRGRR
EEECCCCCCCHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCEEEECCCCCCH
AFEEEALGLLAARGVDLVLLAGFMRLLSPRFVEPWYGRLLNVHPSLLPDYPGLHVHRRVL
HHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHCCCCCCHHHHHHHH
EAGERETGSTVHFVDQGMDTGPILLQGRVPVLPGDTPEALEARVLRLEHRLYPKAVRLLL
HCCCCCCCCEEEEECCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHH
RGLAFPPPPDLEARLGREAAGAFLALSPREKPLYLRAWALLRAWGQEALVGPAFLGQGGE
HHCCCCCCCCHHHHHCHHHHCEEEEECCCCCCHHHHHHHHHHHHCHHHHCCHHHHCCCCC
WGRGAFLAAHLLAEPSPVLLEEVAGLPGEVRARVEEALRVESSP
CCCHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3301838; 9205837; 9278503; 10954745; 2204419; 1522592; 1631098; 9698564; 10606510 [H]