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The map label for this gene is msrR [H]

Identifier: 55980694

GI number: 55980694

Start: 687608

End: 688753

Strand: Direct

Name: msrR [H]

Synonym: TTHA0725

Alternate gene names: 55980694

Gene position: 687608-688753 (Clockwise)

Preceding gene: 55980693

Following gene: 55980703

Centisome position: 37.17

GC content: 73.21

Gene sequence:

>1146_bases
GTGCGGCGGCTGGCCCTCCTTTTCCCGGTCCTCGCCCTCCTCGTGGGGGTTTGGGTCTTTCCCCTTTTGGGCCCCCTCTT
CCGGCACGGGGCGGTCCCTAACCCCTTCGCCCTGAAGGAGCCCTTCACCCTTTTGGTCTACGGCTCGAGCCCCGAGTACG
TGGGCTACCACAAGAGGGCCCCGGAGCGCTTCCGGGGCCTCGCCGACACCATCCTCCTCGTGCGCCTGGACCCCGGGGCG
AACCGGGTGGTGGTCCTCTCCGTGCCCCGGGACGTCTGGGTCCTGCTTCCCGGCCACGGCTGGCACAAGGTGAACGCCGC
AAGCCCCTTGGGGGGGCCGGAGCTCATGAAGGAGGCCGTGGCCCGGATCACGGGGGTGCGCCCCGACCGCTACGTGGTGG
TGAGCCTCGAGGCCCTCCGCCGGGGCGTGGACGCCCTAGGGGGGGTGCGGGTCTGCGTGGAGAAGCCCATGCGCTACCAG
GACCAGGCGGCGGGGCTTGTTATAGACCTGGAGCCCGGTTGCCAGGTGCTTAGCGGCGCGCAGGCGGAGGGCTACCTCCG
CTTCCGCAAGGACGCCCTGGGGGACATCGGCCGCATCCAGCGCCAGCAGGCCTTCTTCCACGCCCTGAAGGACCAGCTTT
TCTCTCTGCCGGGCCTCCTCCGCCTCCCCCGGGCGGTGGCGGCGGTGGAGCCCTACGTGGCCACCGACCTCACCCGGGGG
GAGAAGGGGGCCTTGCTCGGCTTCCTCCTCCGCAGGCCCGCCTTCGTGAGCCTCCTCCTTCCCGGGCGGTTCGCCGGGGG
CTGGGCGGTGGACGAGGCGGCCTGGGCCCGGCTTCGGGCGGTCTACTTTGAGGACCGGGAGGCCTGGGGCGAGGCCTTGG
CGGGGAAGCGGGCCGTGGTCCTCTTCGGGCCCGGCCAGGAGGCCCTGGCCCAGGAGGCGGCGGAGCGGCTTAAGGCCTTG
GGCCTCTCGGTGAGCCTGCGGGAGCTCGCCCTGGCCCCCGGGCGCACGGAGGTGCTGGAAAACGGCCCGGGCCGCCTCGC
CCAGGCCTTGGGCGAGGCCCTCGGCGTCCCCTACCGCGTCTCCGGGGAGGCGGCCTTGGGGGCGGACCTCACCCTGCGCC
TGGGCAGGGAGGGGCTTCCCCGTTGA

Upstream 100 bases:

>100_bases
AATACGGCTTCGGCCTGGTCCGGGCCGACCGGGCGATGACGGACACCACCTACTGCTTCCCCTAATCCGCCTCACCCAAA
GGGGGCTACACTAGGGCTTC

Downstream 100 bases:

>100_bases
GGCCACCCCAATGCTGGCCCAAGCCAGCATGGGGGCCCCGGCACAAAAGGTCCCTAGGGGGCTTCCTTGGGGCATTCGGG
CGAAGGATGAGCCCTCCACC

Product: membrane-bound protein LytR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MRRLALLFPVLALLVGVWVFPLLGPLFRHGAVPNPFALKEPFTLLVYGSSPEYVGYHKRAPERFRGLADTILLVRLDPGA
NRVVVLSVPRDVWVLLPGHGWHKVNAASPLGGPELMKEAVARITGVRPDRYVVVSLEALRRGVDALGGVRVCVEKPMRYQ
DQAAGLVIDLEPGCQVLSGAQAEGYLRFRKDALGDIGRIQRQQAFFHALKDQLFSLPGLLRLPRAVAAVEPYVATDLTRG
EKGALLGFLLRRPAFVSLLLPGRFAGGWAVDEAAWARLRAVYFEDREAWGEALAGKRAVVLFGPGQEALAQEAAERLKAL
GLSVSLRELALAPGRTEVLENGPGRLAQALGEALGVPYRVSGEAALGADLTLRLGREGLPR

Sequences:

>Translated_381_residues
MRRLALLFPVLALLVGVWVFPLLGPLFRHGAVPNPFALKEPFTLLVYGSSPEYVGYHKRAPERFRGLADTILLVRLDPGA
NRVVVLSVPRDVWVLLPGHGWHKVNAASPLGGPELMKEAVARITGVRPDRYVVVSLEALRRGVDALGGVRVCVEKPMRYQ
DQAAGLVIDLEPGCQVLSGAQAEGYLRFRKDALGDIGRIQRQQAFFHALKDQLFSLPGLLRLPRAVAAVEPYVATDLTRG
EKGALLGFLLRRPAFVSLLLPGRFAGGWAVDEAAWARLRAVYFEDREAWGEALAGKRAVVLFGPGQEALAQEAAERLKAL
GLSVSLRELALAPGRTEVLENGPGRLAQALGEALGVPYRVSGEAALGADLTLRLGREGLPR
>Mature_381_residues
MRRLALLFPVLALLVGVWVFPLLGPLFRHGAVPNPFALKEPFTLLVYGSSPEYVGYHKRAPERFRGLADTILLVRLDPGA
NRVVVLSVPRDVWVLLPGHGWHKVNAASPLGGPELMKEAVARITGVRPDRYVVVSLEALRRGVDALGGVRVCVEKPMRYQ
DQAAGLVIDLEPGCQVLSGAQAEGYLRFRKDALGDIGRIQRQQAFFHALKDQLFSLPGLLRLPRAVAAVEPYVATDLTRG
EKGALLGFLLRRPAFVSLLLPGRFAGGWAVDEAAWARLRAVYFEDREAWGEALAGKRAVVLFGPGQEALAQEAAERLKAL
GLSVSLRELALAPGRTEVLENGPGRLAQALGEALGVPYRVSGEAALGADLTLRLGREGLPR

Specific function: Involved in sarA attenuation. Affects resistance to oxacillin and teicoplanin, as well as the synthesis of virulence factors [H]

COG id: COG1316

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LytR/CpsA/Psr regulatory protein family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004474 [H]

Pfam domain/function: PF03816 LytR_cpsA_psr [H]

EC number: NA

Molecular weight: Translated: 41309; Mature: 41309

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRLALLFPVLALLVGVWVFPLLGPLFRHGAVPNPFALKEPFTLLVYGSSPEYVGYHKRA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCC
PERFRGLADTILLVRLDPGANRVVVLSVPRDVWVLLPGHGWHKVNAASPLGGPELMKEAV
CHHHHCHHHEEEEEEECCCCCEEEEEEECCCEEEEECCCCCEECCCCCCCCCHHHHHHHH
ARITGVRPDRYVVVSLEALRRGVDALGGVRVCVEKPMRYQDQAAGLVIDLEPGCQVLSGA
HHHHCCCCCCEEEEEHHHHHCCHHHHCCHHHHHHCCCCCCHHHCCEEEECCCCCHHHCCC
QAEGYLRFRKDALGDIGRIQRQQAFFHALKDQLFSLPGLLRLPRAVAAVEPYVATDLTRG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHCCCCC
EKGALLGFLLRRPAFVSLLLPGRFAGGWAVDEAAWARLRAVYFEDREAWGEALAGKRAVV
CCHHHHHHHHHCCHHEEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
LFGPGQEALAQEAAERLKALGLSVSLRELALAPGRTEVLENGPGRLAQALGEALGVPYRV
EECCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHCCCEEE
SGEAALGADLTLRLGREGLPR
CCCCCCCCCEEEEECCCCCCC
>Mature Secondary Structure
MRRLALLFPVLALLVGVWVFPLLGPLFRHGAVPNPFALKEPFTLLVYGSSPEYVGYHKRA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCC
PERFRGLADTILLVRLDPGANRVVVLSVPRDVWVLLPGHGWHKVNAASPLGGPELMKEAV
CHHHHCHHHEEEEEEECCCCCEEEEEEECCCEEEEECCCCCEECCCCCCCCCHHHHHHHH
ARITGVRPDRYVVVSLEALRRGVDALGGVRVCVEKPMRYQDQAAGLVIDLEPGCQVLSGA
HHHHCCCCCCEEEEEHHHHHCCHHHHCCHHHHHHCCCCCCHHHCCEEEECCCCCHHHCCC
QAEGYLRFRKDALGDIGRIQRQQAFFHALKDQLFSLPGLLRLPRAVAAVEPYVATDLTRG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHCCCCC
EKGALLGFLLRRPAFVSLLLPGRFAGGWAVDEAAWARLRAVYFEDREAWGEALAGKRAVV
CCHHHHHHHHHCCHHEEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
LFGPGQEALAQEAAERLKALGLSVSLRELALAPGRTEVLENGPGRLAQALGEALGVPYRV
EECCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHCCCEEE
SGEAALGADLTLRLGREGLPR
CCCCCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12878519 [H]