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The map label for this gene is yfjD [C]

Identifier: 55980703

GI number: 55980703

Start: 700284

End: 701621

Strand: Direct

Name: yfjD [C]

Synonym: TTHA0734

Alternate gene names: 55980703

Gene position: 700284-701621 (Clockwise)

Preceding gene: 55980694

Following gene: 55980704

Centisome position: 37.86

GC content: 66.59

Gene sequence:

>1338_bases
ATGGATCGTCCTCCGAGTCGGTGGCTTCTTCTCTTGGCCCTCGGTACCCCGGCTTTGGCGCAAAGCGAGGCGGCTTCCCC
GGAAAACCCGTGGCTTTGGGTCCTCGTCCTCCTCTTCGCCCTCTCCGCCTTCTTCTCCGCAAGCGAGACGGCCATCACCA
CCCTCTACCCGTGGAAGCTGAGGGAGCTCGCCGAAAGCAAAAACGGCCCCTTCCGCCTCCTTTCCAAGGACATCACCCGC
TTCCTCACCACCATCCTCGTGGGCAACAACCTGGTGAACATCGCCGCCACCGCCTTGGTCACGGAGCTCGCCACCCGGGC
CTTCGGCTCCGCGGGCGTGGGGGTGGCCACGGGGGCGATGACCTTCCTCATCCTCTTCTTCGGCGAGATCACCCCCAAGG
CCCTCGCCGTCCACCACGCGGAGGCCATCGCCCGGCTGGCCGCTTGGCCCATTTACGGCCTCTCCGTCCTCTTCTACCCC
CTCGGGCGCTTCTTCAGCCTCGTCTCCGGGGGGCTTCTCCGCCTCCTCGGCCTGGAGCCCCGGGGCACCCCTTTGGTCTC
CGAGGAGGAGCTTAAGCTCATCCTGGCGGGGGCCGAGGAGTCCGGGGCCATTGAGCCCCAGGAGGAGGAGATGATCCACT
CCATCCTGGAGCTGGAGGAGACCCCGGTGCGGGAGATCATGACCCCGAGGGTGGAGATGGTGGCCATAGAGGACGAGGCC
ACCCTGGAGGACCTCCTCGCCCTCTACCGGGAGCACCGCTACAGCCGGGTGCCCGTCTACCGGGAGAGCGTGGACCACAT
CGTGGGGGTGGCCTACGTCCAGGACCTCCTCACCTACTACTGCGAGGAGGACCTCAAGGCCTTCAAGGTGGCCTCCATCG
CCCACCCTCCCTACTTCGTCCCCGAGAACATGGACGCCTGGAGCCTTCTCAAGGAGCTCAGGCGCCGCAAGGTGCACATG
GCCATCGTGGTGGACGAGTTCGGGGGCACGGCGGGCCTCGTAACCCTCGAGGACGTGATAGAGGAGATCGTGGGGGAGAT
CTACGACGAAAGCGACGAGCCCGAGGAGCACCCCATCCGGCTTCTCCCCGACGGCGCCTACTCCATCCAGGCCCAAACCC
CCATAGACGAGGTCTCCGAGGCCTTGGGGGTGGAGCTCCCCGAGGGGGAGTACGACACCCTCTCCGGCTTCCTCTACGCC
CTCTTCGGGCGGATCCCCAGCGTGGGGGAGAGCCTGGAGTGGCAGGGCTTCCGCTTCGTGGTGGAAAGCGCCGACCAGAG
GCGCCTGGAGCGGATCCGGGTGGAACGGGTGGTGGAGCGTGAACGCCAAGGCGGTTAA

Upstream 100 bases:

>100_bases
TGCGCGCCTGGGTTTCGCCCCGGGGGATGCCCGGGCGAGGGCCGCGGGAAACCCTTTGGGGTACGTGGCGGCGGGCCTGG
TGTAGAATGGCGGAAGGCGT

Downstream 100 bases:

>100_bases
GGAGGTGTTGAAGGCCCACGTGGGGCGGGCCTACGCCCCCTACTCGGGCTTCCCCGTGGTGGCCCTGGTGGAGGCGGAAG
GGGAGGTGTTCCTCGGGGTC

Product: hemolysin-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MDRPPSRWLLLLALGTPALAQSEAASPENPWLWVLVLLFALSAFFSASETAITTLYPWKLRELAESKNGPFRLLSKDITR
FLTTILVGNNLVNIAATALVTELATRAFGSAGVGVATGAMTFLILFFGEITPKALAVHHAEAIARLAAWPIYGLSVLFYP
LGRFFSLVSGGLLRLLGLEPRGTPLVSEEELKLILAGAEESGAIEPQEEEMIHSILELEETPVREIMTPRVEMVAIEDEA
TLEDLLALYREHRYSRVPVYRESVDHIVGVAYVQDLLTYYCEEDLKAFKVASIAHPPYFVPENMDAWSLLKELRRRKVHM
AIVVDEFGGTAGLVTLEDVIEEIVGEIYDESDEPEEHPIRLLPDGAYSIQAQTPIDEVSEALGVELPEGEYDTLSGFLYA
LFGRIPSVGESLEWQGFRFVVESADQRRLERIRVERVVERERQGG

Sequences:

>Translated_445_residues
MDRPPSRWLLLLALGTPALAQSEAASPENPWLWVLVLLFALSAFFSASETAITTLYPWKLRELAESKNGPFRLLSKDITR
FLTTILVGNNLVNIAATALVTELATRAFGSAGVGVATGAMTFLILFFGEITPKALAVHHAEAIARLAAWPIYGLSVLFYP
LGRFFSLVSGGLLRLLGLEPRGTPLVSEEELKLILAGAEESGAIEPQEEEMIHSILELEETPVREIMTPRVEMVAIEDEA
TLEDLLALYREHRYSRVPVYRESVDHIVGVAYVQDLLTYYCEEDLKAFKVASIAHPPYFVPENMDAWSLLKELRRRKVHM
AIVVDEFGGTAGLVTLEDVIEEIVGEIYDESDEPEEHPIRLLPDGAYSIQAQTPIDEVSEALGVELPEGEYDTLSGFLYA
LFGRIPSVGESLEWQGFRFVVESADQRRLERIRVERVVERERQGG
>Mature_445_residues
MDRPPSRWLLLLALGTPALAQSEAASPENPWLWVLVLLFALSAFFSASETAITTLYPWKLRELAESKNGPFRLLSKDITR
FLTTILVGNNLVNIAATALVTELATRAFGSAGVGVATGAMTFLILFFGEITPKALAVHHAEAIARLAAWPIYGLSVLFYP
LGRFFSLVSGGLLRLLGLEPRGTPLVSEEELKLILAGAEESGAIEPQEEEMIHSILELEETPVREIMTPRVEMVAIEDEA
TLEDLLALYREHRYSRVPVYRESVDHIVGVAYVQDLLTYYCEEDLKAFKVASIAHPPYFVPENMDAWSLLKELRRRKVHM
AIVVDEFGGTAGLVTLEDVIEEIVGEIYDESDEPEEHPIRLLPDGAYSIQAQTPIDEVSEALGVELPEGEYDTLSGFLYA
LFGRIPSVGESLEWQGFRFVVESADQRRLERIRVERVVERERQGG

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=407, Percent_Identity=28.5012285012285, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI94681046, Length=330, Percent_Identity=31.8181818181818, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI40068053, Length=351, Percent_Identity=31.3390313390313, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI40068055, Length=351, Percent_Identity=31.3390313390313, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI40068051, Length=309, Percent_Identity=28.1553398058252, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI40068049, Length=271, Percent_Identity=30.2583025830258, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI145693175, Length=403, Percent_Identity=29.7766749379653, Blast_Score=189, Evalue=2e-49,
Organism=Escherichia coli, GI1786879, Length=272, Percent_Identity=34.9264705882353, Blast_Score=159, Evalue=5e-40,
Organism=Escherichia coli, GI1790664, Length=428, Percent_Identity=26.6355140186916, Blast_Score=141, Evalue=9e-35,
Organism=Escherichia coli, GI87082033, Length=369, Percent_Identity=24.9322493224932, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1788119, Length=238, Percent_Identity=30.2521008403361, Blast_Score=94, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71980512, Length=362, Percent_Identity=30.1104972375691, Blast_Score=87, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6324512, Length=311, Percent_Identity=28.6173633440514, Blast_Score=78, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 49583; Mature: 49583

Theoretical pI: Translated: 4.36; Mature: 4.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRPPSRWLLLLALGTPALAQSEAASPENPWLWVLVLLFALSAFFSASETAITTLYPWKL
CCCCCCCEEEEEEECCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCHHH
RELAESKNGPFRLLSKDITRFLTTILVGNNLVNIAATALVTELATRAFGSAGVGVATGAM
HHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
TFLILFFGEITPKALAVHHAEAIARLAAWPIYGLSVLFYPLGRFFSLVSGGLLRLLGLEP
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCC
RGTPLVSEEELKLILAGAEESGAIEPQEEEMIHSILELEETPVREIMTPRVEMVAIEDEA
CCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCHHHHCCCCEEEEEECCHH
TLEDLLALYREHRYSRVPVYRESVDHIVGVAYVQDLLTYYCEEDLKAFKVASIAHPPYFV
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PENMDAWSLLKELRRRKVHMAIVVDEFGGTAGLVTLEDVIEEIVGEIYDESDEPEEHPIR
CCCCCHHHHHHHHHHCCEEEEEEEECCCCCCCEEEHHHHHHHHHHHHHCCCCCCCCCCEE
LLPDGAYSIQAQTPIDEVSEALGVELPEGEYDTLSGFLYALFGRIPSVGESLEWQGFRFV
EECCCCEEEEECCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
VESADQRRLERIRVERVVERERQGG
HHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDRPPSRWLLLLALGTPALAQSEAASPENPWLWVLVLLFALSAFFSASETAITTLYPWKL
CCCCCCCEEEEEEECCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCHHH
RELAESKNGPFRLLSKDITRFLTTILVGNNLVNIAATALVTELATRAFGSAGVGVATGAM
HHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
TFLILFFGEITPKALAVHHAEAIARLAAWPIYGLSVLFYPLGRFFSLVSGGLLRLLGLEP
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCC
RGTPLVSEEELKLILAGAEESGAIEPQEEEMIHSILELEETPVREIMTPRVEMVAIEDEA
CCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCHHHHCCCCEEEEEECCHH
TLEDLLALYREHRYSRVPVYRESVDHIVGVAYVQDLLTYYCEEDLKAFKVASIAHPPYFV
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PENMDAWSLLKELRRRKVHMAIVVDEFGGTAGLVTLEDVIEEIVGEIYDESDEPEEHPIR
CCCCCHHHHHHHHHHCCEEEEEEEECCCCCCCEEEHHHHHHHHHHHHHCCCCCCCCCCEE
LLPDGAYSIQAQTPIDEVSEALGVELPEGEYDTLSGFLYALFGRIPSVGESLEWQGFRFV
EECCCCEEEEECCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
VESADQRRLERIRVERVVERERQGG
HHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]