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The map label for this gene is cysH [H]

Identifier: 55980638

GI number: 55980638

Start: 635564

End: 636232

Strand: Reverse

Name: cysH [H]

Synonym: TTHA0669

Alternate gene names: 55980638

Gene position: 636232-635564 (Counterclockwise)

Preceding gene: 55980639

Following gene: 55980637

Centisome position: 34.4

GC content: 66.82

Gene sequence:

>669_bases
ATGGACAAGGTGAAGGCGGCCCGGAGCCTGATCCAAGAAGCCCTGGCCCAAAGCCAAAACCCCTGCTTCACCTGCAGCTT
CCAGGCGGAGGACGTGGTGGTCCTCCACCTCCTCCTCAAGGAAAGGCCCGAGATCCCCGTCCTCTTCCTGGACACGGGCT
ACCACTTCCCCGAGGTCTACGCCTACCGGGACGAGCTGCAAAAGCGCCTGGGTTTCCGCCTGGTGAACCTCACCCCCGCT
CTTTCCCGGGAGGAGCAGGAGAGGCTCTACGGCAAGCTCTACGAGACCGACCCTGGCCGCTGCTGCGCCCTCCGCAAGGT
GGAGCCCCTCTTCGCCGCGCTGGAGGCCCACGACACCTGGTTCACGGGGCTTAGGCGGGAGCAGTCCCCCACCCGCAGAA
ACCTCGAGCCCCAGGAGGAGGCCCGCCTCCCCTCGGGCCACCGCCTGAAGAAGGTGAACCCCCTCTACGACTGGACACTT
AAGGAGGTCTTCGCCTACCTGGCCGTGGAGGACCTCCCCTACCTCCCCCTTTACGACCAGGGCTACCTCTCCATCGGTTG
CGCCCCCTGCACGGCGAAGCCCTTGGACCCCTCGGACCCCCGCTCGGGCCGCTGGGCGGGAAAGGGCAAGCTGGAGTGCG
GCATCCACCTGCACGGTAAGGAGGGGTAG

Upstream 100 bases:

>100_bases
GGATCGTGGACCAGGCCCTGGAGGAGCTGGACCTAGACCCCAAGGAGGGCCTGGGAAGGGCCAAGGAGAAGGCCCAGGAG
GCCCTAAAGGAGGTGGCGGC

Downstream 100 bases:

>100_bases
ATGGCCTTTCTGCTGGGCTTTCTCATCGCCTTCGCCATCGGGGTCACGGGGGTGGGGGCGGGGACGGTTACGGCGCCCCT
CCTCATCCTCGCCCTGGGGC

Product: phosphoadenosine phosphosulfate reductase CysH

Products: NA

Alternate protein names: 3'-phosphoadenylylsulfate reductase; PAPS reductase, thioredoxin dependent; PAPS sulfotransferase; PAdoPS reductase [H]

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MDKVKAARSLIQEALAQSQNPCFTCSFQAEDVVVLHLLLKERPEIPVLFLDTGYHFPEVYAYRDELQKRLGFRLVNLTPA
LSREEQERLYGKLYETDPGRCCALRKVEPLFAALEAHDTWFTGLRREQSPTRRNLEPQEEARLPSGHRLKKVNPLYDWTL
KEVFAYLAVEDLPYLPLYDQGYLSIGCAPCTAKPLDPSDPRSGRWAGKGKLECGIHLHGKEG

Sequences:

>Translated_222_residues
MDKVKAARSLIQEALAQSQNPCFTCSFQAEDVVVLHLLLKERPEIPVLFLDTGYHFPEVYAYRDELQKRLGFRLVNLTPA
LSREEQERLYGKLYETDPGRCCALRKVEPLFAALEAHDTWFTGLRREQSPTRRNLEPQEEARLPSGHRLKKVNPLYDWTL
KEVFAYLAVEDLPYLPLYDQGYLSIGCAPCTAKPLDPSDPRSGRWAGKGKLECGIHLHGKEG
>Mature_222_residues
MDKVKAARSLIQEALAQSQNPCFTCSFQAEDVVVLHLLLKERPEIPVLFLDTGYHFPEVYAYRDELQKRLGFRLVNLTPA
LSREEQERLYGKLYETDPGRCCALRKVEPLFAALEAHDTWFTGLRREQSPTRRNLEPQEEARLPSGHRLKKVNPLYDWTL
KEVFAYLAVEDLPYLPLYDQGYLSIGCAPCTAKPLDPSDPRSGRWAGKGKLECGIHLHGKEG

Specific function: Reduction of activated sulfate into sulfite [H]

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAPS reductase family. CysH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789121, Length=200, Percent_Identity=39, Blast_Score=118, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6325425, Length=206, Percent_Identity=34.9514563106796, Blast_Score=99, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011798
- InterPro:   IPR004511
- InterPro:   IPR002500
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01507 PAPS_reduct [H]

EC number: =1.8.4.8 [H]

Molecular weight: Translated: 25357; Mature: 25357

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKVKAARSLIQEALAQSQNPCFTCSFQAEDVVVLHLLLKERPEIPVLFLDTGYHFPEVY
CCHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHCCCCCCEEEEECCCCCHHHH
AYRDELQKRLGFRLVNLTPALSREEQERLYGKLYETDPGRCCALRKVEPLFAALEAHDTW
HHHHHHHHHHCEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHH
FTGLRREQSPTRRNLEPQEEARLPSGHRLKKVNPLYDWTLKEVFAYLAVEDLPYLPLYDQ
HHHHHCCCCCCCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
GYLSIGCAPCTAKPLDPSDPRSGRWAGKGKLECGIHLHGKEG
CCEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCC
>Mature Secondary Structure
MDKVKAARSLIQEALAQSQNPCFTCSFQAEDVVVLHLLLKERPEIPVLFLDTGYHFPEVY
CCHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHCCCCCCEEEEECCCCCHHHH
AYRDELQKRLGFRLVNLTPALSREEQERLYGKLYETDPGRCCALRKVEPLFAALEAHDTW
HHHHHHHHHHCEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHH
FTGLRREQSPTRRNLEPQEEARLPSGHRLKKVNPLYDWTLKEVFAYLAVEDLPYLPLYDQ
HHHHHCCCCCCCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
GYLSIGCAPCTAKPLDPSDPRSGRWAGKGKLECGIHLHGKEG
CCEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA