| Definition | Thermus thermophilus HB8 chromosome, complete genome. |
|---|---|
| Accession | NC_006461 |
| Length | 1,849,742 |
Click here to switch to the map view.
The map label for this gene is ppdK [H]
Identifier: 55980632
GI number: 55980632
Start: 628449
End: 631046
Strand: Direct
Name: ppdK [H]
Synonym: TTHA0663
Alternate gene names: 55980632
Gene position: 628449-631046 (Clockwise)
Preceding gene: 55980631
Following gene: 55980634
Centisome position: 33.97
GC content: 72.67
Gene sequence:
>2598_bases ATGGCGAAGCGCGTCTACTTGCTCTCCGAGGCCCGGGGGCTTTCCCGGGACCTCTTGGGCGGCAAGGGCCACGGCCTTGC GGAGATGGCGGCGGCGGGCCTGCCCGTCCCCCCGGCCTTCATCGTCACCACGGAGGCCTGCCGCCAGTACCTGAAGGCGG GGGAGGTGCCGGGGCTATGGGGGGAGGTGCGGGCGGGGATGGCGGCCCTAGAGGGCCTAACGGGCAAGCGCTTTGGCCGG GGGGAGGGGAAGGCCCCTCCCCTCCTCGTTTCCGTGCGGAGCGGGGCCCCGGTTTCCATGCCCGGGATGATGGACACCGT CCTCAACCTCGGCCTCACCCTGGAGGGGGTGGAGGCCCTGGCCCGGGCCACGGGCAACCCCCGCTTCGCCTGGGACAGCC TCCGCAGGCTCCTCGCCATGTACGGGGAGGTGGTCTTGGGGGAGGGGCCCGAGGTCTTTGAGGGGATGCTCTCCGCCCTC AAGGCGGAGAGGGGGGTGGGGACGGACGCGGCCCTTGGGCCCGAGGACCTGGAGGAGCTCGCCTACCGCTACCTCCGCCA CCTCGAGGCCCGCGGCACCCCCTTCCCCCTGGACCCCTGGGCCCAACTCCAGGGAGCCATTGAGGCCGTATTCCGGAGCT GGCAGAACCCCAGGGCCAGGACCTACCGCCGCATCTACGGCATCCCCGAGGACCTGGGCACGGCGGTGGTGGTCCAGGCC ATGGTCTTCGGCAACCTGGGGGAGGACTCGGGCACCGGGGTGGGCTTCACCCGCAACCCCGCCACCGGGGAGAAGGGCCT CTACGGGGAGTACCTGAGGAACGCCCAGGGGGAGGACGTGGTGGCGGGCGTCCGCACCCCCGAGCCCCTGGAGCGCCTTA AAGGGTACGCCCCCGGGCTCTACGAGGAGCTCCTCCAGGTGGCGGAGCGCCTGGAGCGGCACTTCCGCGACATGCAGGAC TTTGAGTTCACCGTGGAGCGGGGAAGGCTTTTCCTCCTCCAGACCCGCGCGGGCAAGCGCACGGCCCAGGCGGCGGTGCG GATCGCCGTGGAGATGGCCGAGGAGGGGCTCATCTCCCGGGAGGAGGCGGTCATGAGGGTGGAGGCCAACGCCCTCCCCG GCCTCCTCCGGCCCAGCGTGGACCGGGACCAGGCCCCAAGGCCCCTCCTCAAGGGCCTCCCCGCAAGCCCCGGGGCCGCG GTGGGCCACGCCGCCTTCACCAACGAGGCCGTGGAGCGCTTCCACGCCCAGGGGCTTCCCGCCGTCCTCGTCCGCCCCGA GACCACCCCCGAGGACATCACCGGGATGTACCTCGCCAAGGGGATCCTCACCGCCCGGGGCGGCCTCACCTCCCACGCGG CGGTGGTGGCCCGGGGCCTCGGGGTGCCCGCGGTGGTGGGGGCGGAGGCCCTTAGGGTCTTCCCCGGGGAGGGCCGGGCC CTGGCGGAGGGGGTGGAGATCCGGGAGGGGGACCTCCTCACCCTGGACGGGGGCACGGGGGAGGTGTACCTGGGGGCGGT GCCCCTGGTGGAGGCTGGGGGGGAGGCCCTTTTGGAGAAGCTCCTCTCCTGGGCGGAGCCCCATCGGCGCCTCGGGGTCA GGGCCAACGCCGACACCCCCGAGGACGCCCAAAGGGCCAGGGCCTTCGGGGCCGAGGGGATCGGGCTATGCCGCACGGAG CACATGTTCTTCCGGGAGGACCGCCTCCCTTGGGTGCGCCGCCTCATCCTGGCGGAGACCCCCGAGGAGGAGGCCTTGGC CCTGGAGCGCCTCTTCCACTTCCAGAAGGAGGACTTCAAGGAGATCCTCCGCGCCATGGACGGCCTCCCCGTCACGGTGC GCCTCCTGGACCCGCCGCTTCACGAGTTCCTTCCTCCCCTGGAGGCGCTCGCCCGCCGGGCCGAGGAGGGGGACGAGGAG GCGGGGCGCCTCCTAAGGCGGGCGGAGGCCCTGAAGGAGGCGAACCCCATGCTCGGCTTCCGGGGGGCGAGGCTCCTCCT CCTCAGGCCCGGCGTCTTCCGCATGCAGCTTAGGGCCCTTCTGGAGGCGGCCAGGGAGCTCAAGGAGGCGGGGCACGACC CCAGGCCCGAGGTCATGGTCCCCCTGGTGGCCGACCCCAAGGAGGTGGAAAGGGCGCGGGCCCTCGCCGAGGAGCTCTTC CGGGAGTACGGCCCCATCCCCTTCGGCACCATGGTGGAGACCCCCCGGGCCGCCCTCCTCGCCGCCGAGATCGCCCCTTT GGTGGACTTCTTCAGCTTCGGCACCAACGACCTCACCCAGATGGCCTTCGGCCTCTCCCGGGACGACGCGGGGAAGTTCC TGCCCCGGTACGTGGAGGAGGGGCTTTTCCCCTTTGACCCCACGGAGCGCCTGGACGAGAAGGGGGTGGGGCGGCTTCTC AGGATGGCGGCGGAGGAGGGGAGGAAGGCGAACCCCAGGCTCAAGCTCGGCCTCTGCGGGGAGCACGGGGGGGAGGCGGG AAGCGTCCGCTTCGTGGCGGACCTCTTGGACTACACCTCGGCGAGCCCCTTCCGGGTCCTCACCGCCCGCCTCGCCGCCG CCCAGGCGGGGCTTTCCCGGGCCCTAAAGCCCGCCTAG
Upstream 100 bases:
>100_bases CTCGCCGAGTGGCGGGCCCTCCTTTCCCCTTAGGCGAACGGTGTAGCTCTCCTCGGGCTACACGCTTCCACGCTTCCACG GGCGGGGCCAGAGTGGAGGC
Downstream 100 bases:
>100_bases AGCCGCACCACCACCTTCCCCGTGTGCCCCCGGTCCAGGAGGGCCCGGAAGGCGGCCTCCGCCTCGGCGAAGGGGAAGAC GGGGCCCACCACGGGCCTAA
Product: pyruvate phosphate dikinase
Products: NA
Alternate protein names: Pyruvate, orthophosphate dikinase [H]
Number of amino acids: Translated: 865; Mature: 864
Protein sequence:
>865_residues MAKRVYLLSEARGLSRDLLGGKGHGLAEMAAAGLPVPPAFIVTTEACRQYLKAGEVPGLWGEVRAGMAALEGLTGKRFGR GEGKAPPLLVSVRSGAPVSMPGMMDTVLNLGLTLEGVEALARATGNPRFAWDSLRRLLAMYGEVVLGEGPEVFEGMLSAL KAERGVGTDAALGPEDLEELAYRYLRHLEARGTPFPLDPWAQLQGAIEAVFRSWQNPRARTYRRIYGIPEDLGTAVVVQA MVFGNLGEDSGTGVGFTRNPATGEKGLYGEYLRNAQGEDVVAGVRTPEPLERLKGYAPGLYEELLQVAERLERHFRDMQD FEFTVERGRLFLLQTRAGKRTAQAAVRIAVEMAEEGLISREEAVMRVEANALPGLLRPSVDRDQAPRPLLKGLPASPGAA VGHAAFTNEAVERFHAQGLPAVLVRPETTPEDITGMYLAKGILTARGGLTSHAAVVARGLGVPAVVGAEALRVFPGEGRA LAEGVEIREGDLLTLDGGTGEVYLGAVPLVEAGGEALLEKLLSWAEPHRRLGVRANADTPEDAQRARAFGAEGIGLCRTE HMFFREDRLPWVRRLILAETPEEEALALERLFHFQKEDFKEILRAMDGLPVTVRLLDPPLHEFLPPLEALARRAEEGDEE AGRLLRRAEALKEANPMLGFRGARLLLLRPGVFRMQLRALLEAARELKEAGHDPRPEVMVPLVADPKEVERARALAEELF REYGPIPFGTMVETPRAALLAAEIAPLVDFFSFGTNDLTQMAFGLSRDDAGKFLPRYVEEGLFPFDPTERLDEKGVGRLL RMAAEEGRKANPRLKLGLCGEHGGEAGSVRFVADLLDYTSASPFRVLTARLAAAQAGLSRALKPA
Sequences:
>Translated_865_residues MAKRVYLLSEARGLSRDLLGGKGHGLAEMAAAGLPVPPAFIVTTEACRQYLKAGEVPGLWGEVRAGMAALEGLTGKRFGR GEGKAPPLLVSVRSGAPVSMPGMMDTVLNLGLTLEGVEALARATGNPRFAWDSLRRLLAMYGEVVLGEGPEVFEGMLSAL KAERGVGTDAALGPEDLEELAYRYLRHLEARGTPFPLDPWAQLQGAIEAVFRSWQNPRARTYRRIYGIPEDLGTAVVVQA MVFGNLGEDSGTGVGFTRNPATGEKGLYGEYLRNAQGEDVVAGVRTPEPLERLKGYAPGLYEELLQVAERLERHFRDMQD FEFTVERGRLFLLQTRAGKRTAQAAVRIAVEMAEEGLISREEAVMRVEANALPGLLRPSVDRDQAPRPLLKGLPASPGAA VGHAAFTNEAVERFHAQGLPAVLVRPETTPEDITGMYLAKGILTARGGLTSHAAVVARGLGVPAVVGAEALRVFPGEGRA LAEGVEIREGDLLTLDGGTGEVYLGAVPLVEAGGEALLEKLLSWAEPHRRLGVRANADTPEDAQRARAFGAEGIGLCRTE HMFFREDRLPWVRRLILAETPEEEALALERLFHFQKEDFKEILRAMDGLPVTVRLLDPPLHEFLPPLEALARRAEEGDEE AGRLLRRAEALKEANPMLGFRGARLLLLRPGVFRMQLRALLEAARELKEAGHDPRPEVMVPLVADPKEVERARALAEELF REYGPIPFGTMVETPRAALLAAEIAPLVDFFSFGTNDLTQMAFGLSRDDAGKFLPRYVEEGLFPFDPTERLDEKGVGRLL RMAAEEGRKANPRLKLGLCGEHGGEAGSVRFVADLLDYTSASPFRVLTARLAAAQAGLSRALKPA >Mature_864_residues AKRVYLLSEARGLSRDLLGGKGHGLAEMAAAGLPVPPAFIVTTEACRQYLKAGEVPGLWGEVRAGMAALEGLTGKRFGRG EGKAPPLLVSVRSGAPVSMPGMMDTVLNLGLTLEGVEALARATGNPRFAWDSLRRLLAMYGEVVLGEGPEVFEGMLSALK AERGVGTDAALGPEDLEELAYRYLRHLEARGTPFPLDPWAQLQGAIEAVFRSWQNPRARTYRRIYGIPEDLGTAVVVQAM VFGNLGEDSGTGVGFTRNPATGEKGLYGEYLRNAQGEDVVAGVRTPEPLERLKGYAPGLYEELLQVAERLERHFRDMQDF EFTVERGRLFLLQTRAGKRTAQAAVRIAVEMAEEGLISREEAVMRVEANALPGLLRPSVDRDQAPRPLLKGLPASPGAAV GHAAFTNEAVERFHAQGLPAVLVRPETTPEDITGMYLAKGILTARGGLTSHAAVVARGLGVPAVVGAEALRVFPGEGRAL AEGVEIREGDLLTLDGGTGEVYLGAVPLVEAGGEALLEKLLSWAEPHRRLGVRANADTPEDAQRARAFGAEGIGLCRTEH MFFREDRLPWVRRLILAETPEEEALALERLFHFQKEDFKEILRAMDGLPVTVRLLDPPLHEFLPPLEALARRAEEGDEEA GRLLRRAEALKEANPMLGFRGARLLLLRPGVFRMQLRALLEAARELKEAGHDPRPEVMVPLVADPKEVERARALAEELFR EYGPIPFGTMVETPRAALLAAEIAPLVDFFSFGTNDLTQMAFGLSRDDAGKFLPRYVEEGLFPFDPTERLDEKGVGRLLR MAAEEGRKANPRLKLGLCGEHGGEAGSVRFVADLLDYTSASPFRVLTARLAAAQAGLSRALKPA
Specific function: Catalyzes the reversible phosphorylation of pyruvate and phosphate. In E.histolytica and C.symbiosus, PPDK functions in the direction of ATP synthesis [H]
COG id: COG0574
COG function: function code G; Phosphoenolpyruvate synthase/pyruvate phosphate dikinase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the PEP-utilizing enzyme family [H]
Homologues:
Organism=Escherichia coli, GI1788756, Length=430, Percent_Identity=28.8372093023256, Blast_Score=120, Evalue=4e-28, Organism=Escherichia coli, GI1787994, Length=701, Percent_Identity=26.8188302425107, Blast_Score=105, Evalue=1e-23, Organism=Escherichia coli, GI1788726, Length=423, Percent_Identity=26.9503546099291, Blast_Score=105, Evalue=1e-23, Organism=Escherichia coli, GI48994992, Length=379, Percent_Identity=27.4406332453826, Blast_Score=100, Evalue=5e-22, Organism=Escherichia coli, GI1789193, Length=410, Percent_Identity=25.8536585365854, Blast_Score=97, Evalue=5e-21,
Paralogues:
None
Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2659 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 4,000 Molecules/Cell In: Glucose minimal media [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR013815 - InterPro: IPR013816 - InterPro: IPR008279 - InterPro: IPR018274 - InterPro: IPR023151 - InterPro: IPR000121 - InterPro: IPR002192 - InterPro: IPR010121 - InterPro: IPR015813 [H]
Pfam domain/function: PF00391 PEP-utilizers; PF02896 PEP-utilizers_C; PF01326 PPDK_N [H]
EC number: =2.7.9.1 [H]
Molecular weight: Translated: 93938; Mature: 93807
Theoretical pI: Translated: 5.43; Mature: 5.43
Prosite motif: PS00370 PEP_ENZYMES_PHOS_SITE ; PS00742 PEP_ENZYMES_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.3 %Cys (Translated Protein) 2.4 %Met (Translated Protein) 2.8 %Cys+Met (Translated Protein) 0.3 %Cys (Mature Protein) 2.3 %Met (Mature Protein) 2.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MAKRVYLLSEARGLSRDLLGGKGHGLAEMAAAGLPVPPAFIVTTEACRQYLKAGEVPGLW CCCEEEEHHHHCCCHHHHCCCCCCCHHHHHHCCCCCCCHHEEEHHHHHHHHHCCCCCCCH GEVRAGMAALEGLTGKRFGRGEGKAPPLLVSVRSGAPVSMPGMMDTVLNLGLTLEGVEAL HHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHCCCCHHHHHHH ARATGNPRFAWDSLRRLLAMYGEVVLGEGPEVFEGMLSALKAERGVGTDAALGPEDLEEL HHCCCCCCHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH AYRYLRHLEARGTPFPLDPWAQLQGAIEAVFRSWQNPRARTYRRIYGIPEDLGTAVVVQA HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHH MVFGNLGEDSGTGVGFTRNPATGEKGLYGEYLRNAQGEDVVAGVRTPEPLERLKGYAPGL HHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCEEECCCCCHHHHHHCCCCCHH YEELLQVAERLERHFRDMQDFEFTVERGRLFLLQTRAGKRTAQAAVRIAVEMAEEGLISR HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCH EEAVMRVEANALPGLLRPSVDRDQAPRPLLKGLPASPGAAVGHAAFTNEAVERFHAQGLP HHHHHHHCCCCCCCHHCCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCC AVLVRPETTPEDITGMYLAKGILTARGGLTSHAAVVARGLGVPAVVGAEALRVFPGEGRA EEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHCCHHHEECCCCCCH LAEGVEIREGDLLTLDGGTGEVYLGAVPLVEAGGEALLEKLLSWAEPHRRLGVRANADTP HHCCCEECCCCEEEEECCCCEEEEECCHHHHCCCHHHHHHHHHHHCHHHHCCCCCCCCCC EDAQRARAFGAEGIGLCRTEHMFFREDRLPWVRRLILAETPEEEALALERLFHFQKEDFK HHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH EILRAMDGLPVTVRLLDPPLHEFLPPLEALARRAEEGDEEAGRLLRRAEALKEANPMLGF HHHHHHCCCCEEEEECCCCHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCC RGARLLLLRPGVFRMQLRALLEAARELKEAGHDPRPEVMVPLVADPKEVERARALAEELF CCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHH REYGPIPFGTMVETPRAALLAAEIAPLVDFFSFGTNDLTQMAFGLSRDDAGKFLPRYVEE HHHCCCCCCHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHC GLFPFDPTERLDEKGVGRLLRMAAEEGRKANPRLKLGLCGEHGGEAGSVRFVADLLDYTS CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHCC ASPFRVLTARLAAAQAGLSRALKPA CCHHHHHHHHHHHHHHHHHHCCCCC >Mature Secondary Structure AKRVYLLSEARGLSRDLLGGKGHGLAEMAAAGLPVPPAFIVTTEACRQYLKAGEVPGLW CCEEEEHHHHCCCHHHHCCCCCCCHHHHHHCCCCCCCHHEEEHHHHHHHHHCCCCCCCH GEVRAGMAALEGLTGKRFGRGEGKAPPLLVSVRSGAPVSMPGMMDTVLNLGLTLEGVEAL HHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHCCCCHHHHHHH ARATGNPRFAWDSLRRLLAMYGEVVLGEGPEVFEGMLSALKAERGVGTDAALGPEDLEEL HHCCCCCCHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH AYRYLRHLEARGTPFPLDPWAQLQGAIEAVFRSWQNPRARTYRRIYGIPEDLGTAVVVQA HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHH MVFGNLGEDSGTGVGFTRNPATGEKGLYGEYLRNAQGEDVVAGVRTPEPLERLKGYAPGL HHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCEEECCCCCHHHHHHCCCCCHH YEELLQVAERLERHFRDMQDFEFTVERGRLFLLQTRAGKRTAQAAVRIAVEMAEEGLISR HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCH EEAVMRVEANALPGLLRPSVDRDQAPRPLLKGLPASPGAAVGHAAFTNEAVERFHAQGLP HHHHHHHCCCCCCCHHCCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCC AVLVRPETTPEDITGMYLAKGILTARGGLTSHAAVVARGLGVPAVVGAEALRVFPGEGRA EEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHCCHHHEECCCCCCH LAEGVEIREGDLLTLDGGTGEVYLGAVPLVEAGGEALLEKLLSWAEPHRRLGVRANADTP HHCCCEECCCCEEEEECCCCEEEEECCHHHHCCCHHHHHHHHHHHCHHHHCCCCCCCCCC EDAQRARAFGAEGIGLCRTEHMFFREDRLPWVRRLILAETPEEEALALERLFHFQKEDFK HHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH EILRAMDGLPVTVRLLDPPLHEFLPPLEALARRAEEGDEEAGRLLRRAEALKEANPMLGF HHHHHHCCCCEEEEECCCCHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCC RGARLLLLRPGVFRMQLRALLEAARELKEAGHDPRPEVMVPLVADPKEVERARALAEELF CCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHH REYGPIPFGTMVETPRAALLAAEIAPLVDFFSFGTNDLTQMAFGLSRDDAGKFLPRYVEE HHHCCCCCCHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHC GLFPFDPTERLDEKGVGRLLRMAAEEGRKANPRLKLGLCGEHGGEAGSVRFVADLLDYTS CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHCC ASPFRVLTARLAAAQAGLSRALKPA CCHHHHHHHHHHHHHHHHHHCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 2176881; 6257292; 11695893; 11468288; 8610096; 9753432 [H]