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The map label for this gene is clpX [H]

Identifier: 55980585

GI number: 55980585

Start: 584860

End: 586059

Strand: Direct

Name: clpX [H]

Synonym: TTHA0616

Alternate gene names: 55980585

Gene position: 584860-586059 (Clockwise)

Preceding gene: 55980584

Following gene: 55980587

Centisome position: 31.62

GC content: 67.42

Gene sequence:

>1200_bases
GTGAAGAGGCCTAGGCCCCACTGCAGCTTCTGCGGCCTCCGCCCCCCCGAGACGGGGCGGCTTCTGGAAAGCCCCCTTGA
GGACGTCTACATCTGCGAGGACTGCGTGGAAAGGGCCCAGGAGATCCTGGCCCAGGAGGAGCGCCGCGCCCCCAAGGGGC
CGAGCCGCCTCCCCCGGCCCCAGGAGATCAAGGCCCACCTGGACCAGTACGTGGTGGGGCAGGAGGCGGCCAAAAGGGCC
CTAAGCGTGGCCGTCTACAACCACTACAAGCGGCTCCTCCACCCCGAGGCGGAGATCGGCAAGGCCAACATCCTCCTCAT
CGGCCCCACGGGCACGGGCAAGACCCTCCTCGCCGAAACCCTGGCCCGCTTCCTGGACGTGCCCTTCGCCATCGCCGACG
CCACCACCCTCACCGAGGCCGGGTACGTGGGCGAGGACGTGGAGAACGTCCTCCTCCGCCTCTTGCAGAACGCCGACTTT
GACGTGGAGCGGGCGGAGATGGGCATCGTCTACATTGACGAGATTGACAAGATCGCCCGCAAGTCGGAAAACCCCTCCCT
CACCCGGGACGTCTCCGGGGAGGGGGTGCAGCAGGCCCTCCTGAAGATCATTGAGGGGACCGTGGCCAACGTCCCGCCCC
AGGGAGGGAGGAAGCACCCCCACCAGGAGTTCATCCCGGTGAACACCAAGAACATCCTCTTTATCCTGGGCGGGGCCTTT
GAGGGGCTGGAGAACATCGTCAAGGCCCGGGTGGGAAAGACCACCATCGGCTTCACCGGGGGGAGGAGGGAGCGGGAGGA
GCCCCTGGAGGTCATCCCTGAGGACCTCATCAAGTTCGGCATGATCCCCGAGTTCGTGGGGCGGGCCCCCCTCATCGTCC
AGCTCCACCCCCTCACGGAGGACGACCTGGTGCGCATCCTCACCGAGCCCAAGAACGCCCTGGTGAAGCAGTACCAGGAG
CTCTTCCGCATGGAGGGCATAGAGCTCCGCTTCACCCAGGCGGCCCTCAAGGAGGTGGCCCGGCGCGCCCTCAAGCGGGG
CACGGGGGCGAGGGGCCTCAGGGCCATCCTGGAGAAGGCCATGGTGGACCTGATGTTTGAGGCCCCGGGGAGCGGGGTGC
GGGAGATCGTCTTTGACCTCCCCCACCTGGACCACCCCCTGAAGGCCCTCGAGGAGGCCAGGCTCCGGCAGGCCTCCTAA

Upstream 100 bases:

>100_bases
GGCCAGCCCCTGGAGAAGGTGGAGAAGGACACGGACCGGGACTACTACCTCTCGGCCCAGGAGGCCCTGGAGTACGGCCT
CATTGACCAGGTGGTGACCC

Downstream 100 bases:

>100_bases
GGGCGACCAAGCCCCTTTTGGGGGGCTTAGCCCTCGAGCCGCCGCACCAATTCCTCCTTCAGGGCGAAAAGCCTCTCCGT
GAGGGAGACGTGGTAGACGT

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MKRPRPHCSFCGLRPPETGRLLESPLEDVYICEDCVERAQEILAQEERRAPKGPSRLPRPQEIKAHLDQYVVGQEAAKRA
LSVAVYNHYKRLLHPEAEIGKANILLIGPTGTGKTLLAETLARFLDVPFAIADATTLTEAGYVGEDVENVLLRLLQNADF
DVERAEMGIVYIDEIDKIARKSENPSLTRDVSGEGVQQALLKIIEGTVANVPPQGGRKHPHQEFIPVNTKNILFILGGAF
EGLENIVKARVGKTTIGFTGGRREREEPLEVIPEDLIKFGMIPEFVGRAPLIVQLHPLTEDDLVRILTEPKNALVKQYQE
LFRMEGIELRFTQAALKEVARRALKRGTGARGLRAILEKAMVDLMFEAPGSGVREIVFDLPHLDHPLKALEEARLRQAS

Sequences:

>Translated_399_residues
MKRPRPHCSFCGLRPPETGRLLESPLEDVYICEDCVERAQEILAQEERRAPKGPSRLPRPQEIKAHLDQYVVGQEAAKRA
LSVAVYNHYKRLLHPEAEIGKANILLIGPTGTGKTLLAETLARFLDVPFAIADATTLTEAGYVGEDVENVLLRLLQNADF
DVERAEMGIVYIDEIDKIARKSENPSLTRDVSGEGVQQALLKIIEGTVANVPPQGGRKHPHQEFIPVNTKNILFILGGAF
EGLENIVKARVGKTTIGFTGGRREREEPLEVIPEDLIKFGMIPEFVGRAPLIVQLHPLTEDDLVRILTEPKNALVKQYQE
LFRMEGIELRFTQAALKEVARRALKRGTGARGLRAILEKAMVDLMFEAPGSGVREIVFDLPHLDHPLKALEEARLRQAS
>Mature_399_residues
MKRPRPHCSFCGLRPPETGRLLESPLEDVYICEDCVERAQEILAQEERRAPKGPSRLPRPQEIKAHLDQYVVGQEAAKRA
LSVAVYNHYKRLLHPEAEIGKANILLIGPTGTGKTLLAETLARFLDVPFAIADATTLTEAGYVGEDVENVLLRLLQNADF
DVERAEMGIVYIDEIDKIARKSENPSLTRDVSGEGVQQALLKIIEGTVANVPPQGGRKHPHQEFIPVNTKNILFILGGAF
EGLENIVKARVGKTTIGFTGGRREREEPLEVIPEDLIKFGMIPEFVGRAPLIVQLHPLTEDDLVRILTEPKNALVKQYQE
LFRMEGIELRFTQAALKEVARRALKRGTGARGLRAILEKAMVDLMFEAPGSGVREIVFDLPHLDHPLKALEEARLRQAS

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=308, Percent_Identity=50.3246753246753, Blast_Score=290, Evalue=1e-78,
Organism=Escherichia coli, GI1786642, Length=399, Percent_Identity=57.1428571428571, Blast_Score=449, Evalue=1e-127,
Organism=Escherichia coli, GI1790366, Length=228, Percent_Identity=34.6491228070175, Blast_Score=105, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI71982905, Length=293, Percent_Identity=46.7576791808874, Blast_Score=260, Evalue=8e-70,
Organism=Caenorhabditis elegans, GI71982908, Length=293, Percent_Identity=46.7576791808874, Blast_Score=260, Evalue=9e-70,
Organism=Caenorhabditis elegans, GI71988663, Length=326, Percent_Identity=42.0245398773006, Blast_Score=234, Evalue=5e-62,
Organism=Caenorhabditis elegans, GI71988660, Length=158, Percent_Identity=48.1012658227848, Blast_Score=145, Evalue=3e-35,
Organism=Saccharomyces cerevisiae, GI6319704, Length=426, Percent_Identity=39.2018779342723, Blast_Score=284, Evalue=2e-77,
Organism=Drosophila melanogaster, GI24648291, Length=302, Percent_Identity=48.6754966887417, Blast_Score=284, Evalue=7e-77,
Organism=Drosophila melanogaster, GI24648289, Length=302, Percent_Identity=48.6754966887417, Blast_Score=283, Evalue=1e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 44436; Mature: 44436

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRPRPHCSFCGLRPPETGRLLESPLEDVYICEDCVERAQEILAQEERRAPKGPSRLPRP
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
QEIKAHLDQYVVGQEAAKRALSVAVYNHYKRLLHPEAEIGKANILLIGPTGTGKTLLAET
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCEEEEECCCCCCHHHHHHH
LARFLDVPFAIADATTLTEAGYVGEDVENVLLRLLQNADFDVERAEMGIVYIDEIDKIAR
HHHHHCCCHHHHCHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHCCEEEHHHHHHHHH
KSENPSLTRDVSGEGVQQALLKIIEGTVANVPPQGGRKHPHQEFIPVNTKNILFILGGAF
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEECCHH
EGLENIVKARVGKTTIGFTGGRREREEPLEVIPEDLIKFGMIPEFVGRAPLIVQLHPLTE
HHHHHHHHHHHCCCEECCCCCCCCCCCHHHHCCHHHHHHCCCHHHHCCCCEEEEECCCCH
DDLVRILTEPKNALVKQYQELFRMEGIELRFTQAALKEVARRALKRGTGARGLRAILEKA
HHHHHHHHCCHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
MVDLMFEAPGSGVREIVFDLPHLDHPLKALEEARLRQAS
HHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MKRPRPHCSFCGLRPPETGRLLESPLEDVYICEDCVERAQEILAQEERRAPKGPSRLPRP
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
QEIKAHLDQYVVGQEAAKRALSVAVYNHYKRLLHPEAEIGKANILLIGPTGTGKTLLAET
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCEEEEECCCCCCHHHHHHH
LARFLDVPFAIADATTLTEAGYVGEDVENVLLRLLQNADFDVERAEMGIVYIDEIDKIAR
HHHHHCCCHHHHCHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHCCEEEHHHHHHHHH
KSENPSLTRDVSGEGVQQALLKIIEGTVANVPPQGGRKHPHQEFIPVNTKNILFILGGAF
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEECCHH
EGLENIVKARVGKTTIGFTGGRREREEPLEVIPEDLIKFGMIPEFVGRAPLIVQLHPLTE
HHHHHHHHHHHCCCEECCCCCCCCCCCHHHHCCHHHHHHCCCHHHHCCCCEEEEECCCCH
DDLVRILTEPKNALVKQYQELFRMEGIELRFTQAALKEVARRALKRGTGARGLRAILEKA
HHHHHHHHCCHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
MVDLMFEAPGSGVREIVFDLPHLDHPLKALEEARLRQAS
HHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA