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The map label for this gene is ubiE [C]

Identifier: 55980451

GI number: 55980451

Start: 452160

End: 452798

Strand: Direct

Name: ubiE [C]

Synonym: TTHA0482

Alternate gene names: 55980451

Gene position: 452160-452798 (Clockwise)

Preceding gene: 55980450

Following gene: 55980452

Centisome position: 24.44

GC content: 71.52

Gene sequence:

>639_bases
GTGGACCCCTTCGCTTCTCTAGCCGAGGCCTACGAGGCCTGGTACGGGACCCCCTTGGGGGCCTACGTCATCGCCGAGGA
GGAGAGGGCCCTGAAGGGGCTCCTTCCCCCCGGGGAAAGCCTCCTCGAGGTGGGCGCGGGGACCGGGTACTGGCTTAGGC
GCCTTCCCTATCCCCAAAAGGTGGGGGTGGAGCCTTCCGAGGCCATGCTCGCCGTGGGGAGGAGGCGGGCGCCCGAGGCC
ACCTGGGTGCGGGCTTGGGGCGAGGCCCTGCCCTTCCCCGGGGAAAGCTTTGACGTGGTCCTCCTCTTCACCACCCTGGA
GTTCGTGGAGGACGTGGAGCGGGTCCTCCTCGAGGCCCGGCGCGTCCTCCGTCCGGGCGGGGCCCTTGTGGTGGGGGTCC
TCGAGGCCCTCTCCCCCTGGGCCGCCCTCTACCGGAGGCTTGGGGAAAAGGGCGTCCTCCCCTGGGCCCAGGCCCGCTTC
CTCGCCCGGGAGGACCTGAAGGCCCTCTTGGGGCCTCCTGAGGCGGAAGGGGAAGCGGTGTTTCTCGCCCCCGAGGCCCA
TCCCCCCTACGAGGAGGCGGACCTTGCGGGAAGGCGCGCGGGGAACCGCCCCGCCCTATACTTGGGGAGATGGCGGTGA

Upstream 100 bases:

>100_bases
AGGGTGGTCCTTTCCACCCACCTGGACCGGGAGGAAAGGGTGGGGGAGAGGCTCTTCTTGCGGCCCGACGAGGGCGTGGC
GGTGCGGCTAGACTAGGGGC

Downstream 100 bases:

>100_bases
AGGCCCTCTTCGCCCTTTACCCCCTCCTCCAGGGGGACTACAGGGCGGTGGAGAAAGCCCTCCTGGCCCTGGAGGAAAGC
GGGGCGAGCTACCGCGTCTT

Product: hypothetical protein

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MDPFASLAEAYEAWYGTPLGAYVIAEEERALKGLLPPGESLLEVGAGTGYWLRRLPYPQKVGVEPSEAMLAVGRRRAPEA
TWVRAWGEALPFPGESFDVVLLFTTLEFVEDVERVLLEARRVLRPGGALVVGVLEALSPWAALYRRLGEKGVLPWAQARF
LAREDLKALLGPPEAEGEAVFLAPEAHPPYEEADLAGRRAGNRPALYLGRWR

Sequences:

>Translated_212_residues
MDPFASLAEAYEAWYGTPLGAYVIAEEERALKGLLPPGESLLEVGAGTGYWLRRLPYPQKVGVEPSEAMLAVGRRRAPEA
TWVRAWGEALPFPGESFDVVLLFTTLEFVEDVERVLLEARRVLRPGGALVVGVLEALSPWAALYRRLGEKGVLPWAQARF
LAREDLKALLGPPEAEGEAVFLAPEAHPPYEEADLAGRRAGNRPALYLGRWR
>Mature_212_residues
MDPFASLAEAYEAWYGTPLGAYVIAEEERALKGLLPPGESLLEVGAGTGYWLRRLPYPQKVGVEPSEAMLAVGRRRAPEA
TWVRAWGEALPFPGESFDVVLLFTTLEFVEDVERVLLEARRVLRPGGALVVGVLEALSPWAALYRRLGEKGVLPWAQARF
LAREDLKALLGPPEAEGEAVFLAPEAHPPYEEADLAGRRAGNRPALYLGRWR

Specific function: Methyltransferase Required For The Conversion Of Dimethylmenaquinone (Dmkh2) To Menaquinone (Mkh2) And The Conversion Of 2-Polyprenyl-6-Methoxy-1,4-Benzoquinol (Ddmqh2) To 2-Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol (Dmqh2). [C]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 23361; Mature: 23361

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDPFASLAEAYEAWYGTPLGAYVIAEEERALKGLLPPGESLLEVGAGTGYWLRRLPYPQK
CCHHHHHHHHHHHHCCCCCCEEEEECHHHHHHCCCCCCHHHHHHCCCCCHHHHHCCCCHH
VGVEPSEAMLAVGRRRAPEATWVRAWGEALPFPGESFDVVLLFTTLEFVEDVERVLLEAR
CCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
RVLRPGGALVVGVLEALSPWAALYRRLGEKGVLPWAQARFLAREDLKALLGPPEAEGEAV
HHHCCCCHHHHHHHHHHCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEE
FLAPEAHPPYEEADLAGRRAGNRPALYLGRWR
EEECCCCCCHHHHHHHHCCCCCCCEEEEECCC
>Mature Secondary Structure
MDPFASLAEAYEAWYGTPLGAYVIAEEERALKGLLPPGESLLEVGAGTGYWLRRLPYPQK
CCHHHHHHHHHHHHCCCCCCEEEEECHHHHHHCCCCCCHHHHHHCCCCCHHHHHCCCCHH
VGVEPSEAMLAVGRRRAPEATWVRAWGEALPFPGESFDVVLLFTTLEFVEDVERVLLEAR
CCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
RVLRPGGALVVGVLEALSPWAALYRRLGEKGVLPWAQARFLAREDLKALLGPPEAEGEAV
HHHCCCCHHHHHHHHHHCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEE
FLAPEAHPPYEEADLAGRRAGNRPALYLGRWR
EEECCCCCCHHHHHHHHCCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]