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The map label for this gene is aglA [H]

Identifier: 55980450

GI number: 55980450

Start: 450566

End: 452155

Strand: Direct

Name: aglA [H]

Synonym: TTHA0481

Alternate gene names: 55980450

Gene position: 450566-452155 (Clockwise)

Preceding gene: 55980446

Following gene: 55980451

Centisome position: 24.36

GC content: 68.62

Gene sequence:

>1590_bases
ATGAGCTGGTGGCAAAGGGCGGTCATCTACCAGGTCTACCCCCGGAGCTTCCAGGACACGAACGGGGACGGGGTGGGGGA
CCTCGAGGGCATCCGCAGGCGGCTTCCCTACCTCAAGTCCTTGGGGGTGGACGCCCTCTGGCTTTCCCCCTTCTACAAAA
GCCCCATGAAGGACTTCGGCTACGACGTGGCCGACTACTGCGACGTGGACCCCGTCTTCGGGACCCTTCAGGACTTTGAC
CGCCTCCTAGAGGAGGCCCACGCCCTGGGGCTTAAGGTCCTCGTGGACCTGGTGCCGAACCACACCTCCAGCGAGCACCC
CTGGTTCCTGGAGTCCCGCGCCTCCCGGAATAGCCCCAAGCGGGACTGGTACATCTGGAAAGACCCTGCCCCGGACGGCG
GCCCCCCCAACAACTGGCAGAGCTTCTTCGGCGGCCCCGCCTGGACCCTGGACGAGGCCACGGGCCAGTACTACCTCCAC
CTTTTCCTCCCCGAGCAGCCCGACCTCAACTGGCGCAATCCCGAGGTGCGGGAGGCGATCAAGGAGGTCATGCGCTTCTG
GCTCAGGAGGGGGGTGGACGGCTTCCGGGTGGACGTGCTCTGGCTTCTGGGCAAGGACCCGCTCTTCCGGGACGAGCCGG
GAAGCCCCCTTTGGCGGCCCGGCCTTCCTGACCGGGCCCGGCACGAGCACCTCTACACCGAGGACCAGCCGGAGACCTAC
GCCTACGTGCGGGAGATGCGCCAGGTCCTGGACGAGTTCTCCGAGCCGGGGAGGGAGCGGGTGATGGTGGGGGAGATCTA
CCTGCCCTTGCCCCGCCTGGTGCGCTACTACGCCGCCGGGTGCCACCTGCCCTTCAACTTCAGCCTCGTCACCGAGGGGC
TTTCCGACTGGCGGCCCGAGAACCTGGCCCGGATCGTGGAGACCTACGAGGGCCTCCTCTCCCGCTGGGACTGGCCCAAC
TGGGTCCTGGGCAACCACGACCAGCCCCGCCTCGCCTCCCGCCTGGGGGAGCCCCAGGCCCGGGTCGCGGCCATGCTCCT
CTTCACCTTGAGGGGCACCCCCACCTGGTACTACGGGGACGAGCTCGCCCTGCCCAACGGCCTCATCCCCCCGGAGAAGG
TGCAAGACCCCGCGGCCCTAAGGCAGAGGGACCGGGAGCCCACCGCCTACCACACCCTGGGCCGGGACCCCGAGCGGACG
CCCATGCCCTGGGACGCCTCCCCCTACGGGGGGTTTTCCACGGTGGAGCCCTGGCTTCCCCTGAACCCCGACTACAGGAC
GCGGAACGTGGCCGCCCAGGAGAAGGATCCCCGCTCCATGCTCCACCTGGTTAAGCGCCTCATCGCCTTGAGGAAGGACC
CCGACCTTCTCTACGGGGCCTACCGCACCTACCGGGCGAGGGAGGGGGTCTACGCCTACCTCCGGGGGGAGGGGTGGCTT
GTGGCCCTGAACCTCACGGAGAAGGAAAAGGCCCTGGAGCTTCCCCGCGGGGGGAGGGTGGTCCTTTCCACCCACCTGGA
CCGGGAGGAAAGGGTGGGGGAGAGGCTCTTCTTGCGGCCCGACGAGGGCGTGGCGGTGCGGCTAGACTAG

Upstream 100 bases:

>100_bases
CCCGGGGGAGGCTGCTCGCCGCCCTGGCGGGCCGCTATACGCCGGAGGTGCCCCAAAGCGGTGTAGACTCCGGGCCACAA
AGCGGTGTAGACTCCGGGTC

Downstream 100 bases:

>100_bases
GGGCGTGGACCCCTTCGCTTCTCTAGCCGAGGCCTACGAGGCCTGGTACGGGACCCCCTTGGGGGCCTACGTCATCGCCG
AGGAGGAGAGGGCCCTGAAG

Product: oligo-1,6-glucosidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 529; Mature: 528

Protein sequence:

>529_residues
MSWWQRAVIYQVYPRSFQDTNGDGVGDLEGIRRRLPYLKSLGVDALWLSPFYKSPMKDFGYDVADYCDVDPVFGTLQDFD
RLLEEAHALGLKVLVDLVPNHTSSEHPWFLESRASRNSPKRDWYIWKDPAPDGGPPNNWQSFFGGPAWTLDEATGQYYLH
LFLPEQPDLNWRNPEVREAIKEVMRFWLRRGVDGFRVDVLWLLGKDPLFRDEPGSPLWRPGLPDRARHEHLYTEDQPETY
AYVREMRQVLDEFSEPGRERVMVGEIYLPLPRLVRYYAAGCHLPFNFSLVTEGLSDWRPENLARIVETYEGLLSRWDWPN
WVLGNHDQPRLASRLGEPQARVAAMLLFTLRGTPTWYYGDELALPNGLIPPEKVQDPAALRQRDREPTAYHTLGRDPERT
PMPWDASPYGGFSTVEPWLPLNPDYRTRNVAAQEKDPRSMLHLVKRLIALRKDPDLLYGAYRTYRAREGVYAYLRGEGWL
VALNLTEKEKALELPRGGRVVLSTHLDREERVGERLFLRPDEGVAVRLD

Sequences:

>Translated_529_residues
MSWWQRAVIYQVYPRSFQDTNGDGVGDLEGIRRRLPYLKSLGVDALWLSPFYKSPMKDFGYDVADYCDVDPVFGTLQDFD
RLLEEAHALGLKVLVDLVPNHTSSEHPWFLESRASRNSPKRDWYIWKDPAPDGGPPNNWQSFFGGPAWTLDEATGQYYLH
LFLPEQPDLNWRNPEVREAIKEVMRFWLRRGVDGFRVDVLWLLGKDPLFRDEPGSPLWRPGLPDRARHEHLYTEDQPETY
AYVREMRQVLDEFSEPGRERVMVGEIYLPLPRLVRYYAAGCHLPFNFSLVTEGLSDWRPENLARIVETYEGLLSRWDWPN
WVLGNHDQPRLASRLGEPQARVAAMLLFTLRGTPTWYYGDELALPNGLIPPEKVQDPAALRQRDREPTAYHTLGRDPERT
PMPWDASPYGGFSTVEPWLPLNPDYRTRNVAAQEKDPRSMLHLVKRLIALRKDPDLLYGAYRTYRAREGVYAYLRGEGWL
VALNLTEKEKALELPRGGRVVLSTHLDREERVGERLFLRPDEGVAVRLD
>Mature_528_residues
SWWQRAVIYQVYPRSFQDTNGDGVGDLEGIRRRLPYLKSLGVDALWLSPFYKSPMKDFGYDVADYCDVDPVFGTLQDFDR
LLEEAHALGLKVLVDLVPNHTSSEHPWFLESRASRNSPKRDWYIWKDPAPDGGPPNNWQSFFGGPAWTLDEATGQYYLHL
FLPEQPDLNWRNPEVREAIKEVMRFWLRRGVDGFRVDVLWLLGKDPLFRDEPGSPLWRPGLPDRARHEHLYTEDQPETYA
YVREMRQVLDEFSEPGRERVMVGEIYLPLPRLVRYYAAGCHLPFNFSLVTEGLSDWRPENLARIVETYEGLLSRWDWPNW
VLGNHDQPRLASRLGEPQARVAAMLLFTLRGTPTWYYGDELALPNGLIPPEKVQDPAALRQRDREPTAYHTLGRDPERTP
MPWDASPYGGFSTVEPWLPLNPDYRTRNVAAQEKDPRSMLHLVKRLIALRKDPDLLYGAYRTYRAREGVYAYLRGEGWLV
ALNLTEKEKALELPRGGRVVLSTHLDREERVGERLFLRPDEGVAVRLD

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=553, Percent_Identity=37.7938517179023, Blast_Score=350, Evalue=1e-96,
Organism=Homo sapiens, GI61744477, Length=547, Percent_Identity=24.4972577696526, Blast_Score=110, Evalue=4e-24,
Organism=Homo sapiens, GI61744475, Length=547, Percent_Identity=24.4972577696526, Blast_Score=110, Evalue=5e-24,
Organism=Homo sapiens, GI61744481, Length=547, Percent_Identity=24.4972577696526, Blast_Score=109, Evalue=5e-24,
Organism=Homo sapiens, GI61744479, Length=547, Percent_Identity=24.4972577696526, Blast_Score=109, Evalue=6e-24,
Organism=Homo sapiens, GI61744483, Length=547, Percent_Identity=24.4972577696526, Blast_Score=109, Evalue=7e-24,
Organism=Homo sapiens, GI65506891, Length=547, Percent_Identity=24.3144424131627, Blast_Score=108, Evalue=1e-23,
Organism=Escherichia coli, GI1790687, Length=520, Percent_Identity=39.4230769230769, Blast_Score=324, Evalue=9e-90,
Organism=Escherichia coli, GI1786604, Length=478, Percent_Identity=26.3598326359833, Blast_Score=99, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI25147709, Length=558, Percent_Identity=27.2401433691756, Blast_Score=152, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI32565753, Length=518, Percent_Identity=23.9382239382239, Blast_Score=136, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6322245, Length=507, Percent_Identity=37.8698224852071, Blast_Score=314, Evalue=3e-86,
Organism=Saccharomyces cerevisiae, GI6321726, Length=502, Percent_Identity=39.6414342629482, Blast_Score=311, Evalue=2e-85,
Organism=Saccharomyces cerevisiae, GI6324416, Length=498, Percent_Identity=39.1566265060241, Blast_Score=305, Evalue=1e-83,
Organism=Saccharomyces cerevisiae, GI6321731, Length=582, Percent_Identity=34.7079037800687, Blast_Score=303, Evalue=4e-83,
Organism=Saccharomyces cerevisiae, GI6319776, Length=582, Percent_Identity=34.7079037800687, Blast_Score=303, Evalue=5e-83,
Organism=Saccharomyces cerevisiae, GI6322241, Length=498, Percent_Identity=38.9558232931727, Blast_Score=301, Evalue=2e-82,
Organism=Saccharomyces cerevisiae, GI6322021, Length=498, Percent_Identity=38.9558232931727, Blast_Score=301, Evalue=2e-82,
Organism=Drosophila melanogaster, GI24583745, Length=560, Percent_Identity=39.2857142857143, Blast_Score=392, Evalue=1e-109,
Organism=Drosophila melanogaster, GI24586593, Length=521, Percent_Identity=41.2667946257198, Blast_Score=376, Evalue=1e-104,
Organism=Drosophila melanogaster, GI24583747, Length=512, Percent_Identity=40.8203125, Blast_Score=372, Evalue=1e-103,
Organism=Drosophila melanogaster, GI24583749, Length=512, Percent_Identity=40.8203125, Blast_Score=372, Evalue=1e-103,
Organism=Drosophila melanogaster, GI45549022, Length=517, Percent_Identity=37.9110251450677, Blast_Score=365, Evalue=1e-101,
Organism=Drosophila melanogaster, GI24586591, Length=490, Percent_Identity=41.0204081632653, Blast_Score=361, Evalue=1e-100,
Organism=Drosophila melanogaster, GI24586589, Length=520, Percent_Identity=39.0384615384615, Blast_Score=358, Evalue=4e-99,
Organism=Drosophila melanogaster, GI24586599, Length=534, Percent_Identity=39.5131086142322, Blast_Score=357, Evalue=1e-98,
Organism=Drosophila melanogaster, GI24586597, Length=527, Percent_Identity=40.4174573055028, Blast_Score=353, Evalue=1e-97,
Organism=Drosophila melanogaster, GI221330053, Length=500, Percent_Identity=40, Blast_Score=351, Evalue=6e-97,
Organism=Drosophila melanogaster, GI24586587, Length=558, Percent_Identity=37.0967741935484, Blast_Score=349, Evalue=2e-96,
Organism=Drosophila melanogaster, GI281360393, Length=466, Percent_Identity=38.412017167382, Blast_Score=295, Evalue=7e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.20 [H]

Molecular weight: Translated: 61443; Mature: 61312

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWWQRAVIYQVYPRSFQDTNGDGVGDLEGIRRRLPYLKSLGVDALWLSPFYKSPMKDFG
CCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEECCHHHCCHHHHHC
YDVADYCDVDPVFGTLQDFDRLLEEAHALGLKVLVDLVPNHTSSEHPWFLESRASRNSPK
CCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHCCCCCC
RDWYIWKDPAPDGGPPNNWQSFFGGPAWTLDEATGQYYLHLFLPEQPDLNWRNPEVREAI
CCEEEECCCCCCCCCCCCCHHHCCCCCEEEECCCCCEEEEEEECCCCCCCCCCHHHHHHH
KEVMRFWLRRGVDGFRVDVLWLLGKDPLFRDEPGSPLWRPGLPDRARHEHLYTEDQPETY
HHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCHHH
AYVREMRQVLDEFSEPGRERVMVGEIYLPLPRLVRYYAAGCHLPFNFSLVTEGLSDWRPE
HHHHHHHHHHHHHHCCCCCEEEEEHHHCCHHHHHHHHHCCCCCCCCHHHHHCCHHHCCHH
NLARIVETYEGLLSRWDWPNWVLGNHDQPRLASRLGEPQARVAAMLLFTLRGTPTWYYGD
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHCCCCCEECCC
ELALPNGLIPPEKVQDPAALRQRDREPTAYHTLGRDPERTPMPWDASPYGGFSTVEPWLP
CCCCCCCCCCHHHCCCHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
LNPDYRTRNVAAQEKDPRSMLHLVKRLIALRKDPDLLYGAYRTYRAREGVYAYLRGEGWL
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEEECCCEE
VALNLTEKEKALELPRGGRVVLSTHLDREERVGERLFLRPDEGVAVRLD
EEEECCCHHHHHCCCCCCEEEEEECCCHHHHHCCEEEECCCCCEEEEEC
>Mature Secondary Structure 
SWWQRAVIYQVYPRSFQDTNGDGVGDLEGIRRRLPYLKSLGVDALWLSPFYKSPMKDFG
CHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEECCHHHCCHHHHHC
YDVADYCDVDPVFGTLQDFDRLLEEAHALGLKVLVDLVPNHTSSEHPWFLESRASRNSPK
CCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHCCCCCC
RDWYIWKDPAPDGGPPNNWQSFFGGPAWTLDEATGQYYLHLFLPEQPDLNWRNPEVREAI
CCEEEECCCCCCCCCCCCCHHHCCCCCEEEECCCCCEEEEEEECCCCCCCCCCHHHHHHH
KEVMRFWLRRGVDGFRVDVLWLLGKDPLFRDEPGSPLWRPGLPDRARHEHLYTEDQPETY
HHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCHHH
AYVREMRQVLDEFSEPGRERVMVGEIYLPLPRLVRYYAAGCHLPFNFSLVTEGLSDWRPE
HHHHHHHHHHHHHHCCCCCEEEEEHHHCCHHHHHHHHHCCCCCCCCHHHHHCCHHHCCHH
NLARIVETYEGLLSRWDWPNWVLGNHDQPRLASRLGEPQARVAAMLLFTLRGTPTWYYGD
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHCCCCCEECCC
ELALPNGLIPPEKVQDPAALRQRDREPTAYHTLGRDPERTPMPWDASPYGGFSTVEPWLP
CCCCCCCCCCHHHCCCHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
LNPDYRTRNVAAQEKDPRSMLHLVKRLIALRKDPDLLYGAYRTYRAREGVYAYLRGEGWL
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEEECCCEE
VALNLTEKEKALELPRGGRVVLSTHLDREERVGERLFLRPDEGVAVRLD
EEEECCCHHHHHCCCCCCEEEEEECCCHHHHHCCEEEECCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10400573; 11481430 [H]