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The map label for this gene is otsA [H]

Identifier: 55980449

GI number: 55980449

Start: 450176

End: 450460

Strand: Reverse

Name: otsA [H]

Synonym: TTHA0480

Alternate gene names: 55980449

Gene position: 450460-450176 (Counterclockwise)

Preceding gene: 55980453

Following gene: 55980448

Centisome position: 24.35

GC content: 69.47

Gene sequence:

>285_bases
ATGCCGAGGAGCCTCCCTTCCCCGTCCACCACGGGGAGGGGCAGGGGGGTCTCGCTGAAGAAGGGCAGGGTCCTCTCCAA
CCTGGCGGGGGCGGCGGAGTACCTGAAGGAGGCCCTTTTGGTCAACCCCTACGACCTGGACGGGATGGCCCAGGCCTTGG
ACCGGGCCTTACGCATGCCCGGGGGGGAGCGGCGGGAACGGCTTGCCGCCTTGAAGGCCCGCATTGAGGCCTTGGACGTG
CAGGGCTGGGCGGAGCGCTTCCTCGCCTCCTTGGAGGAGGGATGA

Upstream 100 bases:

>100_bases
GGAGTCTACACCGCTTTGTGGCCCGGAGTCTACACCGCTTTGGGGCACCTCCGGCGTATAGCGGCCCGCCAGGGCGGCGA
GCAGCCTCCCCCGGGTCACG

Downstream 100 bases:

>100_bases
GGGCGGAAAACCCCGTCTTCTTTCTGGACTACGACGGCACCCTGGCCCCCATCGCCCAAAGGCCCGAGGAGGCCTTCCCC
CACCCCGAGGCCCCCCGGGT

Product: trehalose-phosphate synthase

Products: NA

Alternate protein names: Osmoregulatory trehalose synthesis protein A; Trehalose-6-phosphate synthase; UDP-glucose-glucosephosphate glucosyltransferase [H]

Number of amino acids: Translated: 94; Mature: 93

Protein sequence:

>94_residues
MPRSLPSPSTTGRGRGVSLKKGRVLSNLAGAAEYLKEALLVNPYDLDGMAQALDRALRMPGGERRERLAALKARIEALDV
QGWAERFLASLEEG

Sequences:

>Translated_94_residues
MPRSLPSPSTTGRGRGVSLKKGRVLSNLAGAAEYLKEALLVNPYDLDGMAQALDRALRMPGGERRERLAALKARIEALDV
QGWAERFLASLEEG
>Mature_93_residues
PRSLPSPSTTGRGRGVSLKKGRVLSNLAGAAEYLKEALLVNPYDLDGMAQALDRALRMPGGERRERLAALKARIEALDVQ
GWAERFLASLEEG

Specific function: Catalyzes the transfer of glucose from UDP-glucose to glucose-6-phosphate to form alpha,alpha-1,1 trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor [H]

COG id: COG0380

COG function: function code G; Trehalose-6-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 20 family [H]

Homologues:

Organism=Escherichia coli, GI1788206, Length=70, Percent_Identity=48.5714285714286, Blast_Score=62, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001830
- InterPro:   IPR012766 [H]

Pfam domain/function: PF00982 Glyco_transf_20 [H]

EC number: =2.4.1.15 [H]

Molecular weight: Translated: 10192; Mature: 10061

Theoretical pI: Translated: 10.22; Mature: 10.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRSLPSPSTTGRGRGVSLKKGRVLSNLAGAAEYLKEALLVNPYDLDGMAQALDRALRMP
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCC
GGERRERLAALKARIEALDVQGWAERFLASLEEG
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
PRSLPSPSTTGRGRGVSLKKGRVLSNLAGAAEYLKEALLVNPYDLDGMAQALDRALRMP
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCC
GGERRERLAALKARIEALDVQGWAERFLASLEEG
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA