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The map label for this gene is lnt [H]

Identifier: 55980453

GI number: 55980453

Start: 453668

End: 455098

Strand: Reverse

Name: lnt [H]

Synonym: TTHA0484

Alternate gene names: 55980453

Gene position: 455098-453668 (Counterclockwise)

Preceding gene: 55980455

Following gene: 55980449

Centisome position: 24.6

GC content: 69.6

Gene sequence:

>1431_bases
GTGAAGGTCCGAGAGGACCCCAAGGCGCATGGCCCCATTCTCCCACCTCCGCCGTCAAAACCCGGTGAAAAGGAACCGGG
AAGCCCGTATGGTGGAAGGGTGAAGGCCTTGGCCTTGGGCCTCCTCCTCGCCCTCACCCTCCCCCCCTTTCCCCTGGGCT
TCCTCGCCCCCTTCGTCCTCGCCTTCCTCCTCAAGGGGGGCTTCCGGGAAGGGTTCTGGGCGGGCCTGGGGTTTTGGGGG
CTCCACCTGGTCTGGCTCCCGCAAAGCTTCGCCCAGAACTTCGGCCCCTGGGGGGCGGTGCCCTTTCTGCCCCTCGTCCT
CGTCAAGGCCCTCTCCTTCGGCCTCCTCTTCGCCCTCACCCCCAACGCCCCCATGCGCCTCGGGGGGTGGGTTCTCCTGG
AGTGGCTCACGGAGCAAGGAGAACTCGCCTTCCCCTGGGGGTTTCTGGGCTACGCCCTGGTGGAGGCCCCGGGCCGCATC
CTCGCCGCCTGGGGCGGGGTCTACCTCCTCTCCCTCCTCGTCCTCCTCGTGGCCTATGGCCTTCGGGCGAGGCGGCCTTG
GGTCCTCCTCCTTTGGGCCCTCCTCTGGCTCCTTCCCCTCCCCGAGGCGCACCCCGAGGGCAAGGCCCTTTTGGTCCAGG
GGAACATCAACCCCTTAAGGAAGTTCCAGGGGGAGCTGGACGAGGCGGTCTACCTGAGGCTCACCGAGGCGGGGCTTCGG
GCCCACCCCGAGGCGGACCTCGTGGTCTGGCCCGAGACCGCGGTCTGGCGGATCCCCCAGGAGGCGGAGGCCCTCCTCCA
AGGCCGCCCCCTCCTCACCGGCCTCAACCTCCTCGGCCCCAACCGGGCGGTGCTCTACCGGGAGGGCAAGCTCCTCGGCC
ACTACGACAAGACCCGCCTCGTCCCCTTCGGGGAGCGCTTTCCCTTCCGGGAGGCCCTGGGAGGGGTCTACGCCTTCTTC
TTCCGGGCCATGGGGCTTGGGGACCTCCAAGACCGCACCCCTGGCGAGAAGGTGGCCCCCATCGGGCCCTACGGCGTCCT
CATCTGCTACGAGTCCGTCTTTCCCTCCGTGGCCCGGGGCCTGGCGCGGGAAGGGGCCAGGGTCCTCGTCCTCCTCACCA
ACGACGCCTGGTTCGGCCCCTCCTTCGGGGGCAGGCAACACTTCGCCCTGGGACGCCTAAGGGCGGTGGAGACGGGGCGG
TGGCTCCTCAGGGCCGGGAACGACGGGATCACCGCAAGCGTTGACCCCTTCGGCCGGGTGGTGGCGGAAATCCCCCCGCA
CCAAGAGGGCTTCCTCCTCGCCCCTTACGCCCTAAGGACGGGCCTCACCCCTTACGCCCGCTTCGGGGACTGGGCGGTGG
GCCTGGCGTTGACCATCTTCCTCCTTGGCCTTATCCTTAGGGTGCGTCCGCCGGGGTGGCGGAACCGGTAG

Upstream 100 bases:

>100_bases
GGTGGGGCCCGTAGCCCACCAGGTCCCCGAGGACCAGAACCTCGTCCACCCCCTCGGCCCGTAGGGCCTCCAGGGCGGCC
TCGAGGGCGGGGAGGTTGGC

Downstream 100 bases:

>100_bases
ACGCGGCAGACTCAAAATCTGCTGTCCGCAAGGACGTGCGGGTTCGAGTCCCGCCCCCGGCACCAAGGGGCCCCGAAAGG
GGCCTTGTTTCATTCCAGGC

Product: apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: ALP N-acyltransferase [H]

Number of amino acids: Translated: 476; Mature: 476

Protein sequence:

>476_residues
MKVREDPKAHGPILPPPPSKPGEKEPGSPYGGRVKALALGLLLALTLPPFPLGFLAPFVLAFLLKGGFREGFWAGLGFWG
LHLVWLPQSFAQNFGPWGAVPFLPLVLVKALSFGLLFALTPNAPMRLGGWVLLEWLTEQGELAFPWGFLGYALVEAPGRI
LAAWGGVYLLSLLVLLVAYGLRARRPWVLLLWALLWLLPLPEAHPEGKALLVQGNINPLRKFQGELDEAVYLRLTEAGLR
AHPEADLVVWPETAVWRIPQEAEALLQGRPLLTGLNLLGPNRAVLYREGKLLGHYDKTRLVPFGERFPFREALGGVYAFF
FRAMGLGDLQDRTPGEKVAPIGPYGVLICYESVFPSVARGLAREGARVLVLLTNDAWFGPSFGGRQHFALGRLRAVETGR
WLLRAGNDGITASVDPFGRVVAEIPPHQEGFLLAPYALRTGLTPYARFGDWAVGLALTIFLLGLILRVRPPGWRNR

Sequences:

>Translated_476_residues
MKVREDPKAHGPILPPPPSKPGEKEPGSPYGGRVKALALGLLLALTLPPFPLGFLAPFVLAFLLKGGFREGFWAGLGFWG
LHLVWLPQSFAQNFGPWGAVPFLPLVLVKALSFGLLFALTPNAPMRLGGWVLLEWLTEQGELAFPWGFLGYALVEAPGRI
LAAWGGVYLLSLLVLLVAYGLRARRPWVLLLWALLWLLPLPEAHPEGKALLVQGNINPLRKFQGELDEAVYLRLTEAGLR
AHPEADLVVWPETAVWRIPQEAEALLQGRPLLTGLNLLGPNRAVLYREGKLLGHYDKTRLVPFGERFPFREALGGVYAFF
FRAMGLGDLQDRTPGEKVAPIGPYGVLICYESVFPSVARGLAREGARVLVLLTNDAWFGPSFGGRQHFALGRLRAVETGR
WLLRAGNDGITASVDPFGRVVAEIPPHQEGFLLAPYALRTGLTPYARFGDWAVGLALTIFLLGLILRVRPPGWRNR
>Mature_476_residues
MKVREDPKAHGPILPPPPSKPGEKEPGSPYGGRVKALALGLLLALTLPPFPLGFLAPFVLAFLLKGGFREGFWAGLGFWG
LHLVWLPQSFAQNFGPWGAVPFLPLVLVKALSFGLLFALTPNAPMRLGGWVLLEWLTEQGELAFPWGFLGYALVEAPGRI
LAAWGGVYLLSLLVLLVAYGLRARRPWVLLLWALLWLLPLPEAHPEGKALLVQGNINPLRKFQGELDEAVYLRLTEAGLR
AHPEADLVVWPETAVWRIPQEAEALLQGRPLLTGLNLLGPNRAVLYREGKLLGHYDKTRLVPFGERFPFREALGGVYAFF
FRAMGLGDLQDRTPGEKVAPIGPYGVLICYESVFPSVARGLAREGARVLVLLTNDAWFGPSFGGRQHFALGRLRAVETGR
WLLRAGNDGITASVDPFGRVVAEIPPHQEGFLLAPYALRTGLTPYARFGDWAVGLALTIFLLGLILRVRPPGWRNR

Specific function: Transfers the fatty acyl group on membrane lipoproteins [H]

COG id: COG0815

COG function: function code M; Apolipoprotein N-acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1786878, Length=436, Percent_Identity=30.9633027522936, Blast_Score=130, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004563
- InterPro:   IPR003010 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 2.3.1.- [C]

Molecular weight: Translated: 52339; Mature: 52339

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVREDPKAHGPILPPPPSKPGEKEPGSPYGGRVKALALGLLLALTLPPFPLGFLAPFVL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHH
AFLLKGGFREGFWAGLGFWGLHLVWLPQSFAQNFGPWGAVPFLPLVLVKALSFGLLFALT
HHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHHHHHHCEEEEEC
PNAPMRLGGWVLLEWLTEQGELAFPWGFLGYALVEAPGRILAAWGGVYLLSLLVLLVAYG
CCCCCHHHHHHHHHHHHCCCCEECCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHC
LRARRPWVLLLWALLWLLPLPEAHPEGKALLVQGNINPLRKFQGELDEAVYLRLTEAGLR
CCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHHCCCCCEEEEEEEHHCCC
AHPEADLVVWPETAVWRIPQEAEALLQGRPLLTGLNLLGPNRAVLYREGKLLGHYDKTRL
CCCCCCEEECCCHHEEECCHHHHHHHCCCCHHCCCHHCCCCCEEEEECCCEECCCCCCCC
VPFGERFPFREALGGVYAFFFRAMGLGDLQDRTPGEKVAPIGPYGVLICYESVFPSVARG
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHEEEHHHHHHHHHHH
LAREGARVLVLLTNDAWFGPSFGGRQHFALGRLRAVETGRWLLRAGNDGITASVDPFGRV
HHHCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCEECCCHHHHH
VAEIPPHQEGFLLAPYALRTGLTPYARFGDWAVGLALTIFLLGLILRVRPPGWRNR
HHCCCCCCCCEEECCHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKVREDPKAHGPILPPPPSKPGEKEPGSPYGGRVKALALGLLLALTLPPFPLGFLAPFVL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHH
AFLLKGGFREGFWAGLGFWGLHLVWLPQSFAQNFGPWGAVPFLPLVLVKALSFGLLFALT
HHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHHHHHHCEEEEEC
PNAPMRLGGWVLLEWLTEQGELAFPWGFLGYALVEAPGRILAAWGGVYLLSLLVLLVAYG
CCCCCHHHHHHHHHHHHCCCCEECCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHC
LRARRPWVLLLWALLWLLPLPEAHPEGKALLVQGNINPLRKFQGELDEAVYLRLTEAGLR
CCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHHCCCCCEEEEEEEHHCCC
AHPEADLVVWPETAVWRIPQEAEALLQGRPLLTGLNLLGPNRAVLYREGKLLGHYDKTRL
CCCCCCEEECCCHHEEECCHHHHHHHCCCCHHCCCHHCCCCCEEEEECCCEECCCCCCCC
VPFGERFPFREALGGVYAFFFRAMGLGDLQDRTPGEKVAPIGPYGVLICYESVFPSVARG
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHEEEHHHHHHHHHHH
LAREGARVLVLLTNDAWFGPSFGGRQHFALGRLRAVETGRWLLRAGNDGITASVDPFGRV
HHHCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCEECCCHHHHH
VAEIPPHQEGFLLAPYALRTGLTPYARFGDWAVGLALTIFLLGLILRVRPPGWRNR
HHCCCCCCCCEEECCHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12928499 [H]