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The map label for this gene is acuB [H]

Identifier: 55980443

GI number: 55980443

Start: 443648

End: 444274

Strand: Direct

Name: acuB [H]

Synonym: TTHA0474

Alternate gene names: 55980443

Gene position: 443648-444274 (Clockwise)

Preceding gene: 55980442

Following gene: 55980444

Centisome position: 23.98

GC content: 70.49

Gene sequence:

>627_bases
ATGCTGGTCAGGGACGTGATGAAAAGCCCCGTCCTCACCGTGGGGCCTGAGGCGACCCTCGAGGAGGCCTACAAGCTCCT
CCTGGAAAGGGGGATCCGGCACCTCCCCGTGGTGGAGGAGGGGAGGCTCGTGGGCATCGTCACCGACCGGGACATCCGCC
TCGCCACGAGCCACCTGAACCCCAAGGGGCCCTGCCCCGGGTGCACGCGGGTGGGGGAGGTGATGACCCGGGAGGTGGTC
ACCGCCCACCCCCTAGACCCCGTGGAGGAGGCGGCCCGGGTGATGCGGGAGCGGAAGATCGGGTGCCTTCCCGTCCTCGA
GGACGAGGCCCTGGTGGGCATCGTCACGGGGATTGACCTTCTGGATGCCCTCCTCAGGCTCACCGGGGTCACGGAGCCCT
CGGGCCGCCTCGAGGTGCGCCTCCCTGACCGCCCTGGGGAGCTCGCCCGCCTCACGGGGTTCTTGGCGGGGCGGGGGGTG
AACATCCACTCCCTCCTCTCCTACCCGGAGGGGAGGGAGTTCGTGCGGGCGGTGGTGCGGGTGAACACCCTGGAGACCCA
CCTCCTGGCGGAGGCCCTCCGCCGGGAGGGGTTTGACGTCCTCTGGCCCCCCAAAAAGCCATGGTGA

Upstream 100 bases:

>100_bases
CCGGGCCACTACAAGGCCTGCATCCGGGACGACATCCTCTAAGGCCACCCCAGCTAGAGGGGCCCCGGCTTCCGGGGCCC
GCTCGTCGTATACTGGGCCC

Downstream 100 bases:

>100_bases
TCTACCGGGAGGAGTACCGCCTCTACAACTTCGGGCCCGACCACCCCTTTAGCCCCGTCCGCCTGGAAATGCTCACCTCC
CTCCTCCAGGCCCTCGGGGT

Product: acetoin dehydrogenase AcuB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MLVRDVMKSPVLTVGPEATLEEAYKLLLERGIRHLPVVEEGRLVGIVTDRDIRLATSHLNPKGPCPGCTRVGEVMTREVV
TAHPLDPVEEAARVMRERKIGCLPVLEDEALVGIVTGIDLLDALLRLTGVTEPSGRLEVRLPDRPGELARLTGFLAGRGV
NIHSLLSYPEGREFVRAVVRVNTLETHLLAEALRREGFDVLWPPKKPW

Sequences:

>Translated_208_residues
MLVRDVMKSPVLTVGPEATLEEAYKLLLERGIRHLPVVEEGRLVGIVTDRDIRLATSHLNPKGPCPGCTRVGEVMTREVV
TAHPLDPVEEAARVMRERKIGCLPVLEDEALVGIVTGIDLLDALLRLTGVTEPSGRLEVRLPDRPGELARLTGFLAGRGV
NIHSLLSYPEGREFVRAVVRVNTLETHLLAEALRREGFDVLWPPKKPW
>Mature_208_residues
MLVRDVMKSPVLTVGPEATLEEAYKLLLERGIRHLPVVEEGRLVGIVTDRDIRLATSHLNPKGPCPGCTRVGEVMTREVV
TAHPLDPVEEAARVMRERKIGCLPVLEDEALVGIVTGIDLLDALLRLTGVTEPSGRLEVRLPDRPGELARLTGFLAGRGV
NIHSLLSYPEGREFVRAVVRVNTLETHLLAEALRREGFDVLWPPKKPW

Specific function: Role in growth and sporulation on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source [H]

COG id: COG0517

COG function: function code R; FOG: CBS domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000644 [H]

Pfam domain/function: PF00571 CBS [H]

EC number: NA

Molecular weight: Translated: 23006; Mature: 23006

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVRDVMKSPVLTVGPEATLEEAYKLLLERGIRHLPVVEEGRLVGIVTDRDIRLATSHLN
CCCHHHHHCCCEEECCCHHHHHHHHHHHHHCCHHCCEECCCCEEEEEECCCEEEEECCCC
PKGPCPGCTRVGEVMTREVVTAHPLDPVEEAARVMRERKIGCLPVLEDEALVGIVTGIDL
CCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCEECCCHHHHHHHHHHH
LDALLRLTGVTEPSGRLEVRLPDRPGELARLTGFLAGRGVNIHSLLSYPEGREFVRAVVR
HHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHH
VNTLETHLLAEALRREGFDVLWPPKKPW
HHHHHHHHHHHHHHHCCCCEECCCCCCC
>Mature Secondary Structure
MLVRDVMKSPVLTVGPEATLEEAYKLLLERGIRHLPVVEEGRLVGIVTDRDIRLATSHLN
CCCHHHHHCCCEEECCCHHHHHHHHHHHHHCCHHCCEECCCCEEEEEECCCEEEEECCCC
PKGPCPGCTRVGEVMTREVVTAHPLDPVEEAARVMRERKIGCLPVLEDEALVGIVTGIDL
CCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCEECCCHHHHHHHHHHH
LDALLRLTGVTEPSGRLEVRLPDRPGELARLTGFLAGRGVNIHSLLSYPEGREFVRAVVR
HHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHH
VNTLETHLLAEALRREGFDVLWPPKKPW
HHHHHHHHHHHHHHHCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934817; 9387221; 9384377 [H]