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The map label for this gene is oxaA [H]

Identifier: 55980412

GI number: 55980412

Start: 416233

End: 417525

Strand: Reverse

Name: oxaA [H]

Synonym: TTHA0443

Alternate gene names: 55980412

Gene position: 417525-416233 (Counterclockwise)

Preceding gene: 55980413

Following gene: 55980411

Centisome position: 22.57

GC content: 67.21

Gene sequence:

>1293_bases
ATGAAGAGGCTCCTTGCGGCCTTCCTCTTCCTCCTCCCCGCCCTCGCCCTGGAGGTGGGGTTCAAGGACGCGGACGTCAA
CGGGGACGGGACCCCGGAAAAGGTCGCCGTCACCAACCTCATGGACCTGGCCTTTGACGAGGCGGGCCAGGTGGTGGGCT
GGTACGTGAAGGCCTACAAGGGCACGGCCTTCGGCGACTACGCCCGCGCCCCCAACCTGGCGGCGAACGGCCCCGTCCTC
TCCCCCGTGGGCTTCCGTCCCCTGGAGGCGGAGTTCGCCGTGGAGGACGGCCACCTCCTCGCCCGCTTCCGGGGGGAGGA
GGGGACCCTCACCTACCGCATCCCCAAGGAGCGGTACACCGCGGAGGTGACGGCGGACTTTCCCCTCGTCCTTAAGCTCT
CCGCCCAGGGAAACCCCAAGGCGCTGTTGGAAGGCGCCGCCGAGCCCGCCCCGAGCGGGGAGGGGCGCCTCGTCTACCTC
GCCTGGCAGACCCGGCCCAAGGCGGGCTACGCCCTGGTGGCCTTCGGGGAGGGCCCCTTGGAGGGCAGGCTCGTGGGGCG
CGAGGGGGAGGTGCGGCTTGGGCCGGGAGAAATCCTCAGGGTCTACGGCGGCCAGAACGAGCTCGTCCGCTTCCACGTGG
AAGGCCTCCTCTCCTTCCCCGGCCTCTTCAGCCCCAACCTCTGGGGCCAGCTCTCCTTGGGCCTCCTCTGGATCATGGAG
GCGGCCTACCGCTTCACCGGCAACTGGGGCCTCGCCATCCTCTTCCTGACCCTGGTGGTGCGCCTCCTCCTCTGGCCCCT
CATGCACCAGCAGTTCAAGAGCATGGCGGAGATCCAGCGCCTCCAGCCCCTCATCCAGAAGATCAACGAGAAGTACAAGG
ACGACCCCAACAAGCGGGCGGAGGCCACCATGAAGCTCTACCAGGAGCACCGGGTGAACCCCGCCGCCGGCTGCCTCCCC
CTCCTCATCCAGATGCCCATCCTCTTCATCCTCTGGAAGGTGATCGCCAACTACGAGTTCGGCCAGGGCTTCCTCTGGAT
CCCCGACCTCGCCCTCCCCGACCCCTACTACATCCTCCCCGTCCTCTACGTGGCCAGCACCTTCCTCTCCACCTGGCTCT
CCGCCCACGGGAACCGGGACCTCATCCGGCAAAGCCTCTTCATGAACCTCATCTTCGTCTTCCTGGTCCTCCAGTTCCCC
TCGGGGGTCACCCTCTACTGGGTCCTTTCCACCCTCATCGGCCTCGTGCAGCAGTGGCTCATCAACAAAAGCCTGGCCCC
CCTTAAGGCGTAA

Upstream 100 bases:

>100_bases
TCGCCGTGCGGCGGGTCCTCCGCTGCCACCCCTGGAACCCCGGCGGGCTGGACCCGGTGCCCGTCCTCTTCCCCCCGGGG
AAGGTCCGGGGAGGTGCGGA

Downstream 100 bases:

>100_bases
ACTGGGGGCATGAACGAGCGCAAGAAGAGCATTGACGAGCTCCTCTCCGACCTCGGGGTCCTCGAGGAGGCCCCGGTGGA
AGTGGAGCTCAAGGAATCGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MKRLLAAFLFLLPALALEVGFKDADVNGDGTPEKVAVTNLMDLAFDEAGQVVGWYVKAYKGTAFGDYARAPNLAANGPVL
SPVGFRPLEAEFAVEDGHLLARFRGEEGTLTYRIPKERYTAEVTADFPLVLKLSAQGNPKALLEGAAEPAPSGEGRLVYL
AWQTRPKAGYALVAFGEGPLEGRLVGREGEVRLGPGEILRVYGGQNELVRFHVEGLLSFPGLFSPNLWGQLSLGLLWIME
AAYRFTGNWGLAILFLTLVVRLLLWPLMHQQFKSMAEIQRLQPLIQKINEKYKDDPNKRAEATMKLYQEHRVNPAAGCLP
LLIQMPILFILWKVIANYEFGQGFLWIPDLALPDPYYILPVLYVASTFLSTWLSAHGNRDLIRQSLFMNLIFVFLVLQFP
SGVTLYWVLSTLIGLVQQWLINKSLAPLKA

Sequences:

>Translated_430_residues
MKRLLAAFLFLLPALALEVGFKDADVNGDGTPEKVAVTNLMDLAFDEAGQVVGWYVKAYKGTAFGDYARAPNLAANGPVL
SPVGFRPLEAEFAVEDGHLLARFRGEEGTLTYRIPKERYTAEVTADFPLVLKLSAQGNPKALLEGAAEPAPSGEGRLVYL
AWQTRPKAGYALVAFGEGPLEGRLVGREGEVRLGPGEILRVYGGQNELVRFHVEGLLSFPGLFSPNLWGQLSLGLLWIME
AAYRFTGNWGLAILFLTLVVRLLLWPLMHQQFKSMAEIQRLQPLIQKINEKYKDDPNKRAEATMKLYQEHRVNPAAGCLP
LLIQMPILFILWKVIANYEFGQGFLWIPDLALPDPYYILPVLYVASTFLSTWLSAHGNRDLIRQSLFMNLIFVFLVLQFP
SGVTLYWVLSTLIGLVQQWLINKSLAPLKA
>Mature_430_residues
MKRLLAAFLFLLPALALEVGFKDADVNGDGTPEKVAVTNLMDLAFDEAGQVVGWYVKAYKGTAFGDYARAPNLAANGPVL
SPVGFRPLEAEFAVEDGHLLARFRGEEGTLTYRIPKERYTAEVTADFPLVLKLSAQGNPKALLEGAAEPAPSGEGRLVYL
AWQTRPKAGYALVAFGEGPLEGRLVGREGEVRLGPGEILRVYGGQNELVRFHVEGLLSFPGLFSPNLWGQLSLGLLWIME
AAYRFTGNWGLAILFLTLVVRLLLWPLMHQQFKSMAEIQRLQPLIQKINEKYKDDPNKRAEATMKLYQEHRVNPAAGCLP
LLIQMPILFILWKVIANYEFGQGFLWIPDLALPDPYYILPVLYVASTFLSTWLSAHGNRDLIRQSLFMNLIFVFLVLQFP
SGVTLYWVLSTLIGLVQQWLINKSLAPLKA

Specific function: Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and indepe

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790140, Length=200, Percent_Identity=39.5, Blast_Score=150, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001708 [H]

Pfam domain/function: PF02096 60KD_IMP [H]

EC number: NA

Molecular weight: Translated: 47919; Mature: 47919

Theoretical pI: Translated: 7.69; Mature: 7.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRLLAAFLFLLPALALEVGFKDADVNGDGTPEKVAVTNLMDLAFDEAGQVVGWYVKAYK
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHC
GTAFGDYARAPNLAANGPVLSPVGFRPLEAEFAVEDGHLLARFRGEEGTLTYRIPKERYT
CCCCCCHHCCCCCCCCCCEECCCCCCCCCCEEEECCCEEEEEEECCCCEEEEEECHHHCE
AEVTADFPLVLKLSAQGNPKALLEGAAEPAPSGEGRLVYLAWQTRPKAGYALVAFGEGPL
EEEEECCCEEEEEECCCCCHHHHCCCCCCCCCCCCEEEEEEEECCCCCCEEEEEECCCCC
EGRLVGREGEVRLGPGEILRVYGGQNELVRFHVEGLLSFPGLFSPNLWGQLSLGLLWIME
CCEEECCCCCEEECHHHEEEEECCCCCEEEEEHHHHHHCCCCCCCCCCHHHHHHHHHHHH
AAYRFTGNWGLAILFLTLVVRLLLWPLMHQQFKSMAEIQRLQPLIQKINEKYKDDPNKRA
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
EATMKLYQEHRVNPAAGCLPLLIQMPILFILWKVIANYEFGQGFLWIPDLALPDPYYILP
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCHHHHH
VLYVASTFLSTWLSAHGNRDLIRQSLFMNLIFVFLVLQFPSGVTLYWVLSTLIGLVQQWL
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
INKSLAPLKA
HCCCCCCCCC
>Mature Secondary Structure
MKRLLAAFLFLLPALALEVGFKDADVNGDGTPEKVAVTNLMDLAFDEAGQVVGWYVKAYK
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHC
GTAFGDYARAPNLAANGPVLSPVGFRPLEAEFAVEDGHLLARFRGEEGTLTYRIPKERYT
CCCCCCHHCCCCCCCCCCEECCCCCCCCCCEEEECCCEEEEEEECCCCEEEEEECHHHCE
AEVTADFPLVLKLSAQGNPKALLEGAAEPAPSGEGRLVYLAWQTRPKAGYALVAFGEGPL
EEEEECCCEEEEEECCCCCHHHHCCCCCCCCCCCCEEEEEEEECCCCCCEEEEEECCCCC
EGRLVGREGEVRLGPGEILRVYGGQNELVRFHVEGLLSFPGLFSPNLWGQLSLGLLWIME
CCEEECCCCCEEECHHHEEEEECCCCCEEEEEHHHHHHCCCCCCCCCCHHHHHHHHHHHH
AAYRFTGNWGLAILFLTLVVRLLLWPLMHQQFKSMAEIQRLQPLIQKINEKYKDDPNKRA
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
EATMKLYQEHRVNPAAGCLPLLIQMPILFILWKVIANYEFGQGFLWIPDLALPDPYYILP
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCHHHHH
VLYVASTFLSTWLSAHGNRDLIRQSLFMNLIFVFLVLQFPSGVTLYWVLSTLIGLVQQWL
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
INKSLAPLKA
HCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]