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The map label for this gene is yfjP [H]

Identifier: 55980298

GI number: 55980298

Start: 315725

End: 316282

Strand: Direct

Name: yfjP [H]

Synonym: TTHA0329

Alternate gene names: 55980298

Gene position: 315725-316282 (Clockwise)

Preceding gene: 55980297

Following gene: 55980299

Centisome position: 17.07

GC content: 72.58

Gene sequence:

>558_bases
TTGTTTGAGCACCCCGTCCTCGCCGCCTTTTACCGGCGGCACGGCCCCGCCCCCTTCGCCCCCAACCCCTTTCCCCAAAG
GCCCCCCTTCCGCGTGCTCGCGGAGAGCGTGGTGGCCCAGCAGCTCTCCACCCGGGCGGCCGCCCGCCTCGCCGAGCGCC
TCTTCCGCCTCGTCCCTCCTACCCCGGAGGCCTTCCTCGAGGCCCCCTTGGACCTCCTGCGGCAGGCGGGCCTCTCCCGG
GCCAAGGCCTTGGCCCTGAAAGACCTCGCGGCCAAGGCCGAGGAAGGGCTTCTGGACGGGCTTGACCGCCTGGAGGACGA
GGCGGTGGTGGAGCGCCTCACCCGCGTCCGGGGGGTGGGGCTTTGGACCGCGGAGATGTTTTTGATGTTCGGCCTGGGAA
GGCCCGACGTCTGGCCGGTGCGGGACCTGGGGCTTCGCCGGGCCGCGGCGCGCCTTTTCGGCGTGGCCCCCGAGGCCCTT
CCCGCCTTCGGCGAGGCCTTCCGCCCCTACCGGAGCCACCTCGCGTGGTACCTATGGCGAAGCCTGTCCTCCCCCTAA

Upstream 100 bases:

>100_bases
GATGCCACCAGCGCCCTCACCCCCTTTGACCTGGAGGCCACCTTGCGCCAGGTGACCTTCCTCTACCAGGGCAAGGTCAC
CCGGGCCGAGGGGGTTCGGT

Downstream 100 bases:

>100_bases
AGGAGGCCCCGGCCTCGGGCGAGGTGGCCCTCCTCCGCCTCCTCGAGGCCCGGGGCCAGGAGGTGGTCCCCACCTGGGTG
GTGGACCTGGAGGCGGAGTT

Product: DNA-3-methyladenine glycosidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MFEHPVLAAFYRRHGPAPFAPNPFPQRPPFRVLAESVVAQQLSTRAAARLAERLFRLVPPTPEAFLEAPLDLLRQAGLSR
AKALALKDLAAKAEEGLLDGLDRLEDEAVVERLTRVRGVGLWTAEMFLMFGLGRPDVWPVRDLGLRRAAARLFGVAPEAL
PAFGEAFRPYRSHLAWYLWRSLSSP

Sequences:

>Translated_185_residues
MFEHPVLAAFYRRHGPAPFAPNPFPQRPPFRVLAESVVAQQLSTRAAARLAERLFRLVPPTPEAFLEAPLDLLRQAGLSR
AKALALKDLAAKAEEGLLDGLDRLEDEAVVERLTRVRGVGLWTAEMFLMFGLGRPDVWPVRDLGLRRAAARLFGVAPEAL
PAFGEAFRPYRSHLAWYLWRSLSSP
>Mature_185_residues
MFEHPVLAAFYRRHGPAPFAPNPFPQRPPFRVLAESVVAQQLSTRAAARLAERLFRLVPPTPEAFLEAPLDLLRQAGLSR
AKALALKDLAAKAEEGLLDGLDRLEDEAVVERLTRVRGVGLWTAEMFLMFGLGRPDVWPVRDLGLRRAAARLFGVAPEAL
PAFGEAFRPYRSHLAWYLWRSLSSP

Specific function: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, 3-methylguanine, 7-methylguanine, O2- methylthymine, and O2-methylcytosine from the damaged DNA polymer formed by alkylation lesions [H]

COG id: COG0122

COG function: function code L; 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alkylbase DNA glycosidase alkA family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320990, Length=196, Percent_Identity=29.0816326530612, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011257
- InterPro:   IPR003265
- InterPro:   IPR003583
- InterPro:   IPR023170 [H]

Pfam domain/function: PF00730 HhH-GPD [H]

EC number: =3.2.2.21 [H]

Molecular weight: Translated: 20677; Mature: 20677

Theoretical pI: Translated: 10.68; Mature: 10.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEHPVLAAFYRRHGPAPFAPNPFPQRPPFRVLAESVVAQQLSTRAAARLAERLFRLVPP
CCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TPEAFLEAPLDLLRQAGLSRAKALALKDLAAKAEEGLLDGLDRLEDEAVVERLTRVRGVG
CHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LWTAEMFLMFGLGRPDVWPVRDLGLRRAAARLFGVAPEALPAFGEAFRPYRSHLAWYLWR
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
SLSSP
HHCCC
>Mature Secondary Structure
MFEHPVLAAFYRRHGPAPFAPNPFPQRPPFRVLAESVVAQQLSTRAAARLAERLFRLVPP
CCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TPEAFLEAPLDLLRQAGLSRAKALALKDLAAKAEEGLLDGLDRLEDEAVVERLTRVRGVG
CHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LWTAEMFLMFGLGRPDVWPVRDLGLRRAAARLFGVAPEALPAFGEAFRPYRSHLAWYLWR
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
SLSSP
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377 [H]