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The map label for this gene is perR [H]

Identifier: 55980224

GI number: 55980224

Start: 242597

End: 243040

Strand: Direct

Name: perR [H]

Synonym: TTHA0255

Alternate gene names: 55980224

Gene position: 242597-243040 (Clockwise)

Preceding gene: 55980221

Following gene: 55980226

Centisome position: 13.12

GC content: 65.77

Gene sequence:

>444_bases
ATGCCGAGGACCAAGGAGAAGGAAAGCTACCGCGCGCGGCTAAAGGCGGTGGGCCTGCGCCACACCCTTCCCCGGGAGAG
GATCCTGAGCTTCCTGGACCGCAAAAACGTGCACCCCACCCCGGAGGAGCTCTACCAGGGCCTGAAGAAGCGGGGCTACG
ACATCGGCCTCTCCACCGTTTACCTGAACCTGCACGTCCTCAGGGAGCACGGGCTCATCTACGAGTTCAAGGACCCCAAG
GGAGCCACCCGGTACGACGGCTACAACGAGCCCCACGTGCACCTGGTGTGCACCTCCTGCGGCAAGGTGGAGGACCTGCT
CCTTAAGAACCTTCCCGAGCTGGACGTGAACCCCGCCATGCAGGCGGCCGCCGAGCGCACGGGCTGGGCCCTCGAGGGCT
TCCGCCTGGAGTTCCGGGGGAAGTGCCCGAACTGCCAGAGGTAG

Upstream 100 bases:

>100_bases
GCGGGAAAGGGCCTCGCCCTCCTCTACCACCTCCAGATCCGAAAAGCGTTGCGTTTGCACACCCGGGGTGTATACTGAAA
CTGGTAGGAAAGGAGGAAGG

Downstream 100 bases:

>100_bases
CCGCCTAAGCCTGAGGCCCGGGGGGGTTCCCCGGGCCCGCGCCTTCTTTCCTTCCCCGCGGGACCTAAGCCCGCACGGGG
CGGCCCTACAGGGCCTCCGC

Product: ferric uptake regulation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 147; Mature: 146

Protein sequence:

>147_residues
MPRTKEKESYRARLKAVGLRHTLPRERILSFLDRKNVHPTPEELYQGLKKRGYDIGLSTVYLNLHVLREHGLIYEFKDPK
GATRYDGYNEPHVHLVCTSCGKVEDLLLKNLPELDVNPAMQAAAERTGWALEGFRLEFRGKCPNCQR

Sequences:

>Translated_147_residues
MPRTKEKESYRARLKAVGLRHTLPRERILSFLDRKNVHPTPEELYQGLKKRGYDIGLSTVYLNLHVLREHGLIYEFKDPK
GATRYDGYNEPHVHLVCTSCGKVEDLLLKNLPELDVNPAMQAAAERTGWALEGFRLEFRGKCPNCQR
>Mature_146_residues
PRTKEKESYRARLKAVGLRHTLPRERILSFLDRKNVHPTPEELYQGLKKRGYDIGLSTVYLNLHVLREHGLIYEFKDPKG
ATRYDGYNEPHVHLVCTSCGKVEDLLLKNLPELDVNPAMQAAAERTGWALEGFRLEFRGKCPNCQR

Specific function: Hydrogen and organic peroxide sensor. Represses the expression of a regulon of peroxide-inducible genes such as katA, ahpC, ahpF, the heme biosynthesis operon (hemAXCDBL), fur, perR, zosA and mrgA [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

None

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 16990; Mature: 16859

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRTKEKESYRARLKAVGLRHTLPRERILSFLDRKNVHPTPEELYQGLKKRGYDIGLSTV
CCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHEE
YLNLHVLREHGLIYEFKDPKGATRYDGYNEPHVHLVCTSCGKVEDLLLKNLPELDVNPAM
HHHHEEHCCCCCEEEECCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHCCCCCCCCHHH
QAAAERTGWALEGFRLEFRGKCPNCQR
HHHHHHCCCEEECEEEEECCCCCCCCC
>Mature Secondary Structure 
PRTKEKESYRARLKAVGLRHTLPRERILSFLDRKNVHPTPEELYQGLKKRGYDIGLSTV
CCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHEE
YLNLHVLREHGLIYEFKDPKGATRYDGYNEPHVHLVCTSCGKVEDLLLKNLPELDVNPAM
HHHHEEHCCCCCEEEECCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHCCCCCCCCHHH
QAAAERTGWALEGFRLEFRGKCPNCQR
HHHHHHCCCEEECEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9202460; 9384377; 9701813; 12100544 [H]