BacMap

Definition	Thermus thermophilus HB8 chromosome, complete genome.
Accession	NC_006461
Length	1,849,742

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The map label for this gene is pnbA [H]

Identifier: 55980168

GI number: 55980168

Start: 193971

End: 195518

Strand: Direct

Name: pnbA [H]

Synonym: TTHA0199

Alternate gene names: 55980168

Gene position: 193971-195518 (Clockwise)

Preceding gene: 55980164

Following gene: 55980169

Centisome position: 10.49

GC content: 70.67

Gene sequence:

>1548_bases
ATGCTCCGGCGCCTCCTGCCCTTCCTCGCCCTCCTGGGAGGGGCCCTCGCCCAGGCCTTCTGGGTGGAGACCCCCTTGGG
CCGGGCCCAAGGCCGCCTCGAGGGCGGGGCCATCGCCTTCTACGGCCTCCCCTACGCCGAGGCGGAGCGGTTCCGGGCCC
CGAAGCCCCTAAAGGCCTGGCCCCCCGGCGTGGGCCAGGAAGCGGTGGCCTGCCCCCAGGCCCCGGGGATCACGGCCTGG
TTCGGCGGCCCCATCCCCCTAGAGAGGGAGGACTGCCTGGTCCTCAACGTCTACCTCCCCGCCCAGATCCCGCCCCCGGG
GGGCTTCCCCGTCATGGTCTACCTCCACGGCGGGGGCTTCACCTCGGGGGCAGGGGCCGAGCCCATCTACCGGGGGCACC
GGCTTTCGGAGGAGGGGGTCGTTGTGGTCGCCCCCAACTACCGCCTGGGGCCCTTGGGCTTCCTCGCCCTTCCTGCCCTC
GCCGAGGAGGACCCGAAAGCGGTGGGGAACTACGGGCTTTTGGACGTCCTCGAGGCCCTCCGCTTCGTGAGGGACTATAT
CCGCTACTTCGGGGGCGACCCCAAGAACGTCACCCTCTTCGGGGAGTCCGCCGGGGGGATGCTGGTCTGCACCCTCCTCG
CCACCCCGGAGGCCCGCGGCCTCTTCCAAAAGGCCATCGTCCAATCGGGAGGGTGCGGGTACGTCCGGGCTTTGGAGGAA
GACTACGCCCAGGGGGAGGCCTGGGCCAAGGCGAGGGGGTGCGACCCCAAGGACCTCGCCTGCCTCCGCGCCCTCCCCCT
GGAGAGGCTCTTGCCCGAGGAGCCCACCCTCGAGGCCACGGGCCGCTTCCTCTCAAACCCCTCCCTCTTCCGGACAGGCC
CCTTCAAGCCCCACCTCTCCCCCTTCCTCCTCCCCCAGGACCCCAGGGAGGCCCTAAGGGAGGGAAAGGCGGCGGGCACC
CCCCTCATCGCCGGGGCGAACGCCGAGGAGGTGGCCTTCCCCAGCCTCCAAGCCCTCCTCGGACCCGGGGACTGGGAGGA
GGCGGAAAGGAGGCTTTTGGAGTCTGGGCTTTCCCGGGAGAAGGCCCAGGCCCTCCTCGCCCACTACCGGAAGGGAGTCC
CCGACCCCAAAAGGGCCTGGGGGGAGGTGCAGACCGACCTCACCCTCCTCTGCCCTTCCCTGAAGGCCGCCCGCCTTCAG
GCCCCCCACGCCCCCACCTACGCCTACCTCTTCACCTTCCGGGCGCCGGGGTTTGAGGGCCTCGGGGCCTTCCACGGCCT
GGAGCTCGCCCCCCTCTTCGGGAACCTCCTGGAGAGGCCCTTCCTACCTCTTTTCCTACGCCAAGAAGCCCAAGAGGAGG
CAGAGTACCTGGGCAAGAAGATGCGCCGCTACTGGACCTCTTTCGCCAAGGACGGCGAGCCCAAGGGGTGGCCCCGCTGG
CCCCTCTACCGGGAGGGCCTCCTCCTGCGGCTGGACGTCCCCCTGGGGCTTCTGCCGGACCTTTACGAGGAACGGTGCGG
CGCCCTCGAGGTCCTTGGGCTACTCTAA

Upstream 100 bases:

>100_bases
CCCTCCCCGCCTCGTCCAGACCGGCCACGAGGAGGCCTTTTCGCCAAAAGGGAGCTTCCAAGGGCCCTTCGGCCATGGGG
CCATCTTATACGCTTAGGGC

Downstream 100 bases:

>100_bases
GGGCATGAGGGCCCGCGCCACCTGTCCCCTGGACTGCCCCGACGCCTGCAGCCTCCTCCTCACCCTGGAGGAAGGGCGCC
TCCTCCGGGTGGAGGGGGAC

Product: type B carboxylesterase

Products: NA

Alternate protein names: Intracellular esterase B; PNB carboxy-esterase; PNBCE [H]

Number of amino acids: Translated: 515; Mature: 515

Protein sequence:

>515_residues
MLRRLLPFLALLGGALAQAFWVETPLGRAQGRLEGGAIAFYGLPYAEAERFRAPKPLKAWPPGVGQEAVACPQAPGITAW
FGGPIPLEREDCLVLNVYLPAQIPPPGGFPVMVYLHGGGFTSGAGAEPIYRGHRLSEEGVVVVAPNYRLGPLGFLALPAL
AEEDPKAVGNYGLLDVLEALRFVRDYIRYFGGDPKNVTLFGESAGGMLVCTLLATPEARGLFQKAIVQSGGCGYVRALEE
DYAQGEAWAKARGCDPKDLACLRALPLERLLPEEPTLEATGRFLSNPSLFRTGPFKPHLSPFLLPQDPREALREGKAAGT
PLIAGANAEEVAFPSLQALLGPGDWEEAERRLLESGLSREKAQALLAHYRKGVPDPKRAWGEVQTDLTLLCPSLKAARLQ
APHAPTYAYLFTFRAPGFEGLGAFHGLELAPLFGNLLERPFLPLFLRQEAQEEAEYLGKKMRRYWTSFAKDGEPKGWPRW
PLYREGLLLRLDVPLGLLPDLYEERCGALEVLGLL

Sequences:

>Translated_515_residues
MLRRLLPFLALLGGALAQAFWVETPLGRAQGRLEGGAIAFYGLPYAEAERFRAPKPLKAWPPGVGQEAVACPQAPGITAW
FGGPIPLEREDCLVLNVYLPAQIPPPGGFPVMVYLHGGGFTSGAGAEPIYRGHRLSEEGVVVVAPNYRLGPLGFLALPAL
AEEDPKAVGNYGLLDVLEALRFVRDYIRYFGGDPKNVTLFGESAGGMLVCTLLATPEARGLFQKAIVQSGGCGYVRALEE
DYAQGEAWAKARGCDPKDLACLRALPLERLLPEEPTLEATGRFLSNPSLFRTGPFKPHLSPFLLPQDPREALREGKAAGT
PLIAGANAEEVAFPSLQALLGPGDWEEAERRLLESGLSREKAQALLAHYRKGVPDPKRAWGEVQTDLTLLCPSLKAARLQ
APHAPTYAYLFTFRAPGFEGLGAFHGLELAPLFGNLLERPFLPLFLRQEAQEEAEYLGKKMRRYWTSFAKDGEPKGWPRW
PLYREGLLLRLDVPLGLLPDLYEERCGALEVLGLL
>Mature_515_residues
MLRRLLPFLALLGGALAQAFWVETPLGRAQGRLEGGAIAFYGLPYAEAERFRAPKPLKAWPPGVGQEAVACPQAPGITAW
FGGPIPLEREDCLVLNVYLPAQIPPPGGFPVMVYLHGGGFTSGAGAEPIYRGHRLSEEGVVVVAPNYRLGPLGFLALPAL
AEEDPKAVGNYGLLDVLEALRFVRDYIRYFGGDPKNVTLFGESAGGMLVCTLLATPEARGLFQKAIVQSGGCGYVRALEE
DYAQGEAWAKARGCDPKDLACLRALPLERLLPEEPTLEATGRFLSNPSLFRTGPFKPHLSPFLLPQDPREALREGKAAGT
PLIAGANAEEVAFPSLQALLGPGDWEEAERRLLESGLSREKAQALLAHYRKGVPDPKRAWGEVQTDLTLLCPSLKAARLQ
APHAPTYAYLFTFRAPGFEGLGAFHGLELAPLFGNLLERPFLPLFLRQEAQEEAEYLGKKMRRYWTSFAKDGEPKGWPRW
PLYREGLLLRLDVPLGLLPDLYEERCGALEVLGLL

Specific function: Catalyzes hydrolysis of several beta-lactam antibiotic PNB esters to the corresponding free acid and PNB alcohol [H]

COG id: COG2272

COG function: function code I; Carboxylesterase type B

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-B carboxylesterase/lipase family [H]

Homologues:

Organism=Homo sapiens, GI4557351, Length=513, Percent_Identity=30.7992202729045, Blast_Score=188, Evalue=1e-47,
Organism=Homo sapiens, GI7710112, Length=503, Percent_Identity=32.20675944334, Blast_Score=177, Evalue=3e-44,
Organism=Homo sapiens, GI4557239, Length=503, Percent_Identity=32.20675944334, Blast_Score=176, Evalue=4e-44,
Organism=Homo sapiens, GI37622885, Length=492, Percent_Identity=29.2682926829268, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI297747275, Length=506, Percent_Identity=31.8181818181818, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI33563374, Length=509, Percent_Identity=31.434184675835, Blast_Score=171, Evalue=2e-42,
Organism=Homo sapiens, GI37622887, Length=487, Percent_Identity=28.7474332648871, Blast_Score=166, Evalue=5e-41,
Organism=Homo sapiens, GI219521907, Length=434, Percent_Identity=31.3364055299539, Blast_Score=165, Evalue=8e-41,
Organism=Homo sapiens, GI298231153, Length=434, Percent_Identity=31.3364055299539, Blast_Score=165, Evalue=1e-40,
Organism=Homo sapiens, GI68508957, Length=512, Percent_Identity=31.4453125, Blast_Score=164, Evalue=3e-40,
Organism=Homo sapiens, GI68508967, Length=513, Percent_Identity=31.1890838206628, Blast_Score=163, Evalue=3e-40,
Organism=Homo sapiens, GI68508965, Length=513, Percent_Identity=31.1890838206628, Blast_Score=163, Evalue=3e-40,
Organism=Homo sapiens, GI298231188, Length=457, Percent_Identity=31.7286652078775, Blast_Score=162, Evalue=9e-40,
Organism=Homo sapiens, GI24308209, Length=520, Percent_Identity=28.6538461538462, Blast_Score=156, Evalue=5e-38,
Organism=Homo sapiens, GI31317256, Length=520, Percent_Identity=28.6538461538462, Blast_Score=156, Evalue=5e-38,
Organism=Homo sapiens, GI262359974, Length=522, Percent_Identity=27.9693486590038, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI256222771, Length=520, Percent_Identity=28.2692307692308, Blast_Score=152, Evalue=7e-37,
Organism=Homo sapiens, GI7662470, Length=521, Percent_Identity=28.5988483685221, Blast_Score=151, Evalue=1e-36,
Organism=Homo sapiens, GI51593088, Length=542, Percent_Identity=26.9372693726937, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI298231184, Length=516, Percent_Identity=28.4883720930233, Blast_Score=144, Evalue=3e-34,
Organism=Homo sapiens, GI310117651, Length=512, Percent_Identity=29.6875, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI30840978, Length=308, Percent_Identity=35.3896103896104, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI310117649, Length=514, Percent_Identity=29.7665369649805, Blast_Score=140, Evalue=4e-33,
Organism=Homo sapiens, GI298231190, Length=253, Percent_Identity=37.9446640316205, Blast_Score=139, Evalue=7e-33,
Organism=Homo sapiens, GI262359971, Length=562, Percent_Identity=25.9786476868327, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI148536848, Length=516, Percent_Identity=30.0387596899225, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI310117653, Length=540, Percent_Identity=28.7037037037037, Blast_Score=131, Evalue=2e-30,
Organism=Homo sapiens, GI21450749, Length=253, Percent_Identity=35.9683794466403, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI310117655, Length=406, Percent_Identity=30.7881773399015, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI310117657, Length=398, Percent_Identity=30.6532663316583, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI55770862, Length=500, Percent_Identity=26.6, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI169216018, Length=226, Percent_Identity=32.7433628318584, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI310133037, Length=226, Percent_Identity=32.7433628318584, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI169215613, Length=226, Percent_Identity=32.7433628318584, Blast_Score=100, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17548187, Length=504, Percent_Identity=29.7619047619048, Blast_Score=164, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17537191, Length=545, Percent_Identity=29.7247706422018, Blast_Score=160, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI17537193, Length=514, Percent_Identity=28.0155642023346, Blast_Score=143, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17509963, Length=548, Percent_Identity=27.1897810218978, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17507681, Length=522, Percent_Identity=28.544061302682, Blast_Score=136, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI17559616, Length=510, Percent_Identity=28.8235294117647, Blast_Score=131, Evalue=9e-31,
Organism=Caenorhabditis elegans, GI17564872, Length=503, Percent_Identity=28.0318091451292, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI71981701, Length=479, Percent_Identity=26.3048016701461, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17564870, Length=504, Percent_Identity=28.5714285714286, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI32566411, Length=491, Percent_Identity=29.1242362525458, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI71999970, Length=527, Percent_Identity=27.8937381404175, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17562340, Length=434, Percent_Identity=28.5714285714286, Blast_Score=126, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17558864, Length=498, Percent_Identity=27.710843373494, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI17556436, Length=509, Percent_Identity=27.3084479371316, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17557282, Length=502, Percent_Identity=27.8884462151394, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17558862, Length=513, Percent_Identity=25.1461988304094, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI25146759, Length=285, Percent_Identity=32.9824561403509, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI25146757, Length=285, Percent_Identity=32.9824561403509, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI86563868, Length=532, Percent_Identity=28.0075187969925, Blast_Score=116, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17561818, Length=521, Percent_Identity=25.5278310940499, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI25146735, Length=313, Percent_Identity=30.0319488817891, Blast_Score=114, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI193208562, Length=323, Percent_Identity=30.3405572755418, Blast_Score=114, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI115534610, Length=534, Percent_Identity=26.5917602996255, Blast_Score=114, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17557304, Length=204, Percent_Identity=37.2549019607843, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17568173, Length=207, Percent_Identity=35.7487922705314, Blast_Score=111, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17557292, Length=507, Percent_Identity=25.0493096646943, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17562530, Length=530, Percent_Identity=26.4150943396226, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI32565351, Length=216, Percent_Identity=33.3333333333333, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI72001551, Length=275, Percent_Identity=29.8181818181818, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71996781, Length=275, Percent_Identity=29.8181818181818, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI32564350, Length=434, Percent_Identity=27.6497695852535, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI193209280, Length=293, Percent_Identity=29.6928327645051, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17563740, Length=220, Percent_Identity=31.3636363636364, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71995288, Length=216, Percent_Identity=34.2592592592593, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17538680, Length=498, Percent_Identity=23.8955823293173, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71981720, Length=386, Percent_Identity=24.3523316062176, Blast_Score=95, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI71989495, Length=420, Percent_Identity=27.8571428571429, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI193209277, Length=321, Percent_Identity=26.1682242990654, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17564874, Length=250, Percent_Identity=33.2, Blast_Score=92, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17542512, Length=484, Percent_Identity=23.9669421487603, Blast_Score=92, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI25146726, Length=295, Percent_Identity=28.4745762711864, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17550926, Length=178, Percent_Identity=35.3932584269663, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI32566453, Length=178, Percent_Identity=35.3932584269663, Blast_Score=86, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI71984454, Length=409, Percent_Identity=23.2273838630807, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI115535198, Length=323, Percent_Identity=27.2445820433437, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17566952, Length=309, Percent_Identity=25.2427184466019, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17550574, Length=229, Percent_Identity=29.6943231441048, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI25146753, Length=205, Percent_Identity=29.7560975609756, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24639611, Length=486, Percent_Identity=33.1275720164609, Blast_Score=156, Evalue=3e-38,
Organism=Drosophila melanogaster, GI28571561, Length=496, Percent_Identity=29.4354838709677, Blast_Score=156, Evalue=4e-38,
Organism=Drosophila melanogaster, GI28573188, Length=480, Percent_Identity=31.0416666666667, Blast_Score=156, Evalue=4e-38,
Organism=Drosophila melanogaster, GI24658187, Length=476, Percent_Identity=28.3613445378151, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI21356403, Length=514, Percent_Identity=29.7665369649805, Blast_Score=149, Evalue=3e-36,
Organism=Drosophila melanogaster, GI17737825, Length=434, Percent_Identity=30.6451612903226, Blast_Score=146, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24583084, Length=347, Percent_Identity=33.1412103746398, Blast_Score=145, Evalue=8e-35,
Organism=Drosophila melanogaster, GI24649333, Length=516, Percent_Identity=31.9767441860465, Blast_Score=143, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24649335, Length=516, Percent_Identity=31.9767441860465, Blast_Score=143, Evalue=3e-34,
Organism=Drosophila melanogaster, GI17737813, Length=498, Percent_Identity=29.5180722891566, Blast_Score=142, Evalue=6e-34,
Organism=Drosophila melanogaster, GI221378204, Length=483, Percent_Identity=29.8136645962733, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24644839, Length=438, Percent_Identity=28.9954337899543, Blast_Score=140, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24649337, Length=488, Percent_Identity=32.172131147541, Blast_Score=138, Evalue=8e-33,
Organism=Drosophila melanogaster, GI24644835, Length=511, Percent_Identity=28.7671232876712, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI17737817, Length=480, Percent_Identity=27.9166666666667, Blast_Score=131, Evalue=9e-31,
Organism=Drosophila melanogaster, GI28573189, Length=503, Percent_Identity=28.8270377733598, Blast_Score=130, Evalue=3e-30,
Organism=Drosophila melanogaster, GI17985995, Length=513, Percent_Identity=30.6042884990253, Blast_Score=129, Evalue=7e-30,
Organism=Drosophila melanogaster, GI221473947, Length=500, Percent_Identity=28, Blast_Score=128, Evalue=9e-30,
Organism=Drosophila melanogaster, GI281361699, Length=550, Percent_Identity=26.1818181818182, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI17136862, Length=550, Percent_Identity=26.1818181818182, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI21358071, Length=473, Percent_Identity=27.906976744186, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24582900, Length=549, Percent_Identity=27.3224043715847, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI161077134, Length=432, Percent_Identity=30.3240740740741, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI17737819, Length=518, Percent_Identity=28.5714285714286, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI19920512, Length=386, Percent_Identity=26.4248704663212, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24584490, Length=239, Percent_Identity=38.0753138075314, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI28574499, Length=476, Percent_Identity=27.3109243697479, Blast_Score=120, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24584488, Length=236, Percent_Identity=37.7118644067797, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24584486, Length=236, Percent_Identity=37.7118644067797, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24584484, Length=236, Percent_Identity=37.7118644067797, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI17136262, Length=236, Percent_Identity=37.7118644067797, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI281363491, Length=477, Percent_Identity=29.1404612159329, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI161077136, Length=477, Percent_Identity=29.1404612159329, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24582902, Length=560, Percent_Identity=27.6785714285714, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24665507, Length=424, Percent_Identity=29.9528301886792, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI17136608, Length=424, Percent_Identity=29.9528301886792, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI28571563, Length=148, Percent_Identity=45.2702702702703, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24762554, Length=426, Percent_Identity=26.5258215962441, Blast_Score=112, Evalue=8e-25,
Organism=Drosophila melanogaster, GI281362123, Length=297, Percent_Identity=35.3535353535354, Blast_Score=112, Evalue=9e-25,
Organism=Drosophila melanogaster, GI281362121, Length=297, Percent_Identity=35.3535353535354, Blast_Score=112, Evalue=9e-25,
Organism=Drosophila melanogaster, GI281362119, Length=297, Percent_Identity=35.3535353535354, Blast_Score=112, Evalue=9e-25,
Organism=Drosophila melanogaster, GI281361279, Length=441, Percent_Identity=29.7052154195011, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24644854, Length=441, Percent_Identity=29.7052154195011, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI28574501, Length=524, Percent_Identity=26.9083969465649, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI19922254, Length=300, Percent_Identity=30.3333333333333, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI17647727, Length=276, Percent_Identity=28.9855072463768, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI281361282, Length=279, Percent_Identity=29.3906810035842, Blast_Score=86, Evalue=8e-17,
Organism=Drosophila melanogaster, GI17137794, Length=145, Percent_Identity=37.2413793103448, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24582896, Length=145, Percent_Identity=37.2413793103448, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24582898, Length=145, Percent_Identity=37.2413793103448, Blast_Score=82, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002018
- InterPro:   IPR019826
- InterPro:   IPR019819
- InterPro:   IPR000997 [H]

Pfam domain/function: PF00135 COesterase [H]

EC number: NA

Molecular weight: Translated: 56210; Mature: 56210

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS00122 CARBOXYLESTERASE_B_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRRLLPFLALLGGALAQAFWVETPLGRAQGRLEGGAIAFYGLPYAEAERFRAPKPLKAW
CHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCEEEEECCCHHHHHHCCCCCCCCCC
PPGVGQEAVACPQAPGITAWFGGPIPLEREDCLVLNVYLPAQIPPPGGFPVMVYLHGGGF
CCCCCCCCCCCCCCCCEEEECCCCCCCCCCCEEEEEEEECCCCCCCCCCEEEEEEECCCC
TSGAGAEPIYRGHRLSEEGVVVVAPNYRLGPLGFLALPALAEEDPKAVGNYGLLDVLEAL
CCCCCCCCHHCCCCCCCCCEEEECCCCCCCCHHHHHHHHHCCCCCHHHCCCCHHHHHHHH
RFVRDYIRYFGGDPKNVTLFGESAGGMLVCTLLATPEARGLFQKAIVQSGGCGYVRALEE
HHHHHHHHHHCCCCCEEEEEECCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHH
DYAQGEAWAKARGCDPKDLACLRALPLERLLPEEPTLEATGRFLSNPSLFRTGPFKPHLS
HHHCCHHHHHHCCCCHHHHHHHHHCCHHHHCCCCCCHHHHHHHHCCCCCEECCCCCCCCC
PFLLPQDPREALREGKAAGTPLIAGANAEEVAFPSLQALLGPGDWEEAERRLLESGLSRE
CCCCCCCHHHHHHCCCCCCCCEEECCCCCHHHCHHHHHHCCCCCHHHHHHHHHHHCCCHH
KAQALLAHYRKGVPDPKRAWGEVQTDLTLLCPSLKAARLQAPHAPTYAYLFTFRAPGFEG
HHHHHHHHHHCCCCCHHHHHHHHHCCHHHHCCCHHHHHCCCCCCCCEEEEEEEECCCCCC
LGAFHGLELAPLFGNLLERPFLPLFLRQEAQEEAEYLGKKMRRYWTSFAKDGEPKGWPRW
CHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PLYREGLLLRLDVPLGLLPDLYEERCGALEVLGLL
CHHHCCEEEEECCCCCCCHHHHHHHCCHHHHHHCC
>Mature Secondary Structure
MLRRLLPFLALLGGALAQAFWVETPLGRAQGRLEGGAIAFYGLPYAEAERFRAPKPLKAW
CHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCEEEEECCCHHHHHHCCCCCCCCCC
PPGVGQEAVACPQAPGITAWFGGPIPLEREDCLVLNVYLPAQIPPPGGFPVMVYLHGGGF
CCCCCCCCCCCCCCCCEEEECCCCCCCCCCCEEEEEEEECCCCCCCCCCEEEEEEECCCC
TSGAGAEPIYRGHRLSEEGVVVVAPNYRLGPLGFLALPALAEEDPKAVGNYGLLDVLEAL
CCCCCCCCHHCCCCCCCCCEEEECCCCCCCCHHHHHHHHHCCCCCHHHCCCCHHHHHHHH
RFVRDYIRYFGGDPKNVTLFGESAGGMLVCTLLATPEARGLFQKAIVQSGGCGYVRALEE
HHHHHHHHHHCCCCCEEEEEECCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHH
DYAQGEAWAKARGCDPKDLACLRALPLERLLPEEPTLEATGRFLSNPSLFRTGPFKPHLS
HHHCCHHHHHHCCCCHHHHHHHHHCCHHHHCCCCCCHHHHHHHHCCCCCEECCCCCCCCC
PFLLPQDPREALREGKAAGTPLIAGANAEEVAFPSLQALLGPGDWEEAERRLLESGLSRE
CCCCCCCHHHHHHCCCCCCCCEEECCCCCHHHCHHHHHHCCCCCHHHHHHHHHHHCCCHH
KAQALLAHYRKGVPDPKRAWGEVQTDLTLLCPSLKAARLQAPHAPTYAYLFTFRAPGFEG
HHHHHHHHHHCCCCCHHHHHHHHHCCHHHHCCCHHHHHCCCCCCCCEEEEEEEECCCCCC
LGAFHGLELAPLFGNLLERPFLPLFLRQEAQEEAEYLGKKMRRYWTSFAKDGEPKGWPRW
CHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PLYREGLLLRLDVPLGLLPDLYEERCGALEVLGLL
CHHHCCEEEEECCCCCCCHHHHHHHCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7828905; 8969506; 9384377; 10535917 [H]