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The map label for this gene is prpC [H]

Identifier: 55980156

GI number: 55980156

Start: 183999

End: 184934

Strand: Direct

Name: prpC [H]

Synonym: TTHA0187

Alternate gene names: 55980156

Gene position: 183999-184934 (Clockwise)

Preceding gene: 55980155

Following gene: 55980157

Centisome position: 9.95

GC content: 72.65

Gene sequence:

>936_bases
ATGGACCGCCTCGAGGCCGCCCTGAAGACCCACCCCGGCCTCAAGCGCCCCAAGAACGAGGACGCGGTGGGCGGGGAGGC
CACCCCCTGGGGCGGGGTCTACGTGGTGGCCGACGGCATGGGGGGGCACCGGACGGGGGAGGTGGCCTCGAGGCTCGCCG
TGGAGACCGTCTTGGCGAGGCTTTCCCGGGAGGAACCCCCTTCCCCCAAGGACCTCCTGGAGGCCCTGGAGGAGGCCAAC
GGGAGGATCCACCGGGAGGCCCAGCGCCCGGAGAACCGGGGGATGGGCACCACCTGCACCGTCCTCGTCCTGGACCTGCC
CTACGCCCTGGTGGCCCACGTGGGGGACTCCCGGGCCTATTTGCTCAGGGAGGGGAACCTCCTCCAGCTCACGGAGGACC
ACTCCTGGGTGGCGGAAAGGGTGCGGCAGGGCCTCCTCTCCCCCGAGGAGGCGAGGACGCACCGCTGGCGCAACGTGATC
ACCAACGCCCTGGGCTCCTTCCCCCAGGCCCGGGTGGACCTCCTCGGGCTCAAGCTCCGCCCGGGGGACACCTTCCTCCT
CTGCACCGACGGGCTTTCCGGGGTCCTGGAGGAAAGGGCCCTCAAGGAGGTGCTGGCCCACTTTCCCCCCGCCGAGGCGG
CGGAGCGCCTCGTGGCCCTGGCCAACGAGTGGGGCGGCCCGGACAACGTGAGCGTGGCCGTGGTCCGGGTCCCCGAGGCC
CTGCCGGAGCGCCAGAGGCCCTACGCCCTCCCCCTGGAGGCCGCCAAGGGGGAACCCGTCCGCCTCCAGGTGGGGGAGGT
GCCCGAGGAGCTCACCACCCAGATCCTGGAGCCCGCCCCCAAGAGGGGGCGGGTGGGGTGGCGGGACGCCCTCCTCATTC
TCCTCTGGGTGGTGGTGGTGGCCTACATCCTCCTCAACTCCCTGCGGACCCCCTAG

Upstream 100 bases:

>100_bases
CGCCCTCGAGGTGGCCCTCATCTACGCCCGGCGCCCGCCCCCGCCCAGGCTGGAGGAGGTGCGCCGGCTCCTCCGCGCCC
TCGCCCTGTAGAATGCCCCC

Downstream 100 bases:

>100_bases
ACCCCGGAGGCAGGGGGCGGGTAGACTCTTCGCGGTATGGAGCGGACCTTCGTCATGATCAAGCCCGACGGCGTGCGCCG
GGGCCTTGTGGGGGAGATCC

Product: protein phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MDRLEAALKTHPGLKRPKNEDAVGGEATPWGGVYVVADGMGGHRTGEVASRLAVETVLARLSREEPPSPKDLLEALEEAN
GRIHREAQRPENRGMGTTCTVLVLDLPYALVAHVGDSRAYLLREGNLLQLTEDHSWVAERVRQGLLSPEEARTHRWRNVI
TNALGSFPQARVDLLGLKLRPGDTFLLCTDGLSGVLEERALKEVLAHFPPAEAAERLVALANEWGGPDNVSVAVVRVPEA
LPERQRPYALPLEAAKGEPVRLQVGEVPEELTTQILEPAPKRGRVGWRDALLILLWVVVVAYILLNSLRTP

Sequences:

>Translated_311_residues
MDRLEAALKTHPGLKRPKNEDAVGGEATPWGGVYVVADGMGGHRTGEVASRLAVETVLARLSREEPPSPKDLLEALEEAN
GRIHREAQRPENRGMGTTCTVLVLDLPYALVAHVGDSRAYLLREGNLLQLTEDHSWVAERVRQGLLSPEEARTHRWRNVI
TNALGSFPQARVDLLGLKLRPGDTFLLCTDGLSGVLEERALKEVLAHFPPAEAAERLVALANEWGGPDNVSVAVVRVPEA
LPERQRPYALPLEAAKGEPVRLQVGEVPEELTTQILEPAPKRGRVGWRDALLILLWVVVVAYILLNSLRTP
>Mature_311_residues
MDRLEAALKTHPGLKRPKNEDAVGGEATPWGGVYVVADGMGGHRTGEVASRLAVETVLARLSREEPPSPKDLLEALEEAN
GRIHREAQRPENRGMGTTCTVLVLDLPYALVAHVGDSRAYLLREGNLLQLTEDHSWVAERVRQGLLSPEEARTHRWRNVI
TNALGSFPQARVDLLGLKLRPGDTFLLCTDGLSGVLEERALKEVLAHFPPAEAAERLVALANEWGGPDNVSVAVVRVPEA
LPERQRPYALPLEAAKGEPVRLQVGEVPEELTTQILEPAPKRGRVGWRDALLILLWVVVVAYILLNSLRTP

Specific function: Protein phosphatase that dephosphorylates prkC and fusA (elongation factor G). PrpC and prkC are cotranscribed, which suggests that they form a functional couple in vivo, prpC's primary role being possibly to counter the action of prkC. May be involved in

COG id: COG0631

COG function: function code T; Serine/threonine protein phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015655
- InterPro:   IPR001932
- InterPro:   IPR014045 [H]

Pfam domain/function: PF00481 PP2C [H]

EC number: =3.1.3.16 [H]

Molecular weight: Translated: 34110; Mature: 34110

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRLEAALKTHPGLKRPKNEDAVGGEATPWGGVYVVADGMGGHRTGEVASRLAVETVLAR
CCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHH
LSREEPPSPKDLLEALEEANGRIHREAQRPENRGMGTTCTVLVLDLPYALVAHVGDSRAY
HHCCCCCCHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEE
LLREGNLLQLTEDHSWVAERVRQGLLSPEEARTHRWRNVITNALGSFPQARVDLLGLKLR
EEECCCEEEEECCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHEEEEEC
PGDTFLLCTDGLSGVLEERALKEVLAHFPPAEAAERLVALANEWGGPDNVSVAVVRVPEA
CCCEEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCHH
LPERQRPYALPLEAAKGEPVRLQVGEVPEELTTQILEPAPKRGRVGWRDALLILLWVVVV
CCCCCCCCCCCHHCCCCCCEEEECCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
AYILLNSLRTP
HHHHHHHCCCC
>Mature Secondary Structure
MDRLEAALKTHPGLKRPKNEDAVGGEATPWGGVYVVADGMGGHRTGEVASRLAVETVLAR
CCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHH
LSREEPPSPKDLLEALEEANGRIHREAQRPENRGMGTTCTVLVLDLPYALVAHVGDSRAY
HHCCCCCCHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEE
LLREGNLLQLTEDHSWVAERVRQGLLSPEEARTHRWRNVITNALGSFPQARVDLLGLKLR
EEECCCEEEEECCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHEEEEEC
PGDTFLLCTDGLSGVLEERALKEVLAHFPPAEAAERLVALANEWGGPDNVSVAVVRVPEA
CCCEEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCHH
LPERQRPYALPLEAAKGEPVRLQVGEVPEELTTQILEPAPKRGRVGWRDALLILLWVVVV
CCCCCCCCCCCHHCCCCCCEEEECCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
AYILLNSLRTP
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]