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The map label for this gene is pucG [H]

Identifier: 55980142

GI number: 55980142

Start: 166687

End: 167748

Strand: Reverse

Name: pucG [H]

Synonym: TTHA0173

Alternate gene names: 55980142

Gene position: 167748-166687 (Counterclockwise)

Preceding gene: 55980146

Following gene: 55980140

Centisome position: 9.07

GC content: 73.54

Gene sequence:

>1062_bases
ATGCTGCTTCTGACCCCTGGACCCACCCCCATTCCCGAGCGCGTGCAGAAGGCCCTTCTCCGTCCCATGCGCGGCCACCT
GGACCCCGAGGTCCTCCGGGTGAACCGGGCCATCCAGGAGAGGCTCGCCGCCCTGTTTGACCCCGGGGAGGGCGCCTTGG
TCGCCGCCCTCGCCGGCTCGGGGAGCCTGGGCATGGAGGCGGGCCTCGCCAACCTGGACCGGGGGCCGGTCCTGGTCCTG
GTGAACGGGGCCTTCTCCCAACGCGTGGCGGAGATGGCGGCCCTCCACGGCCTGGACCCCGAGGTCCTGGACTTCCCCCC
GGGGGAGCCCGTGGACCCCGAGGCCGTGGCCCGGGCCTTGAAGCGGCGGCGGTACCGCATGGTGGCCCTGGTGCACGGGG
AGACCTCCACCGGGGTGCTGAACCCGGCGGAGGCCATCGGGGCCCTGGCCAAGGAGGCCGGGGCCCTTTTCTTCCTGGAC
GCCGTGACCACCTTGGGGATGCTCCCCTTCTCCATGCGGGCCATGGGGGTGGACTACGCCTTCACCGGGAGCCAGAAGTG
CCTTTCCGCCCCGCCCGGCCTCGCCCCCATCGCCGCAAGCCTCGAGGCCAGGAAGGCTTTCACGGGGAAACGGGGGTGGT
ACCTGGACCTCGCCCGGGTGGCGGAGCATTGGGAGCGGGGCGGGTACCATCACACCACCCCCGTCCTCCTCCACTACGCC
CTCCTGGAGGCCCTGGACCTGGTCCTGGAGGAGGGGGTGGCGGCCCGGGAGCGGCGCGCCCGTGAGGTCTACGCCTGGGT
CCTGGAGGAGCTTAAGGCCCGGGGCTTCCGGCCCTACCCCAAGGCCAGCCCCCTGCCCACGGTGCTCGTCGTCCGCCCCC
CCGAGGGGGTGGACGCGGACCGCCTGGTCCGGGCCCTCTACGCCGAGGGGGTGGCGGTGGCCGGCGGGATCGGGCCCACC
CGGGGCCAGGTCCTCCGCCTCGGCCTCATGGGGGAGGGGGCCCGGCGGGAGGCGTACCAGGCCTTCTTAAAGGCCTTGGA
CCGGGCTTTGGCCCTAGCGTAG

Upstream 100 bases:

>100_bases
AATGAGGCCCTCGCGAGCTCGCCGGTAGGGGGTCCCTTCCTTCGGGAAGGGGCCCCCGGGGCGTGCCCGCGGGGGCCCGG
CCTTTTTGAGGGAGGCTTGG

Downstream 100 bases:

>100_bases
GAAGAAGAAGGCGTAGACCGCCGCCAGGGCCATGCGGTAGAGGGCGAAGGGGCGGAAGCCGTGGCGGGCCACGAAGGCCA
GCATCCAGCGCACGGTGACC

Product: aminotransferase, class V

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MLLLTPGPTPIPERVQKALLRPMRGHLDPEVLRVNRAIQERLAALFDPGEGALVAALAGSGSLGMEAGLANLDRGPVLVL
VNGAFSQRVAEMAALHGLDPEVLDFPPGEPVDPEAVARALKRRRYRMVALVHGETSTGVLNPAEAIGALAKEAGALFFLD
AVTTLGMLPFSMRAMGVDYAFTGSQKCLSAPPGLAPIAASLEARKAFTGKRGWYLDLARVAEHWERGGYHHTTPVLLHYA
LLEALDLVLEEGVAARERRAREVYAWVLEELKARGFRPYPKASPLPTVLVVRPPEGVDADRLVRALYAEGVAVAGGIGPT
RGQVLRLGLMGEGARREAYQAFLKALDRALALA

Sequences:

>Translated_353_residues
MLLLTPGPTPIPERVQKALLRPMRGHLDPEVLRVNRAIQERLAALFDPGEGALVAALAGSGSLGMEAGLANLDRGPVLVL
VNGAFSQRVAEMAALHGLDPEVLDFPPGEPVDPEAVARALKRRRYRMVALVHGETSTGVLNPAEAIGALAKEAGALFFLD
AVTTLGMLPFSMRAMGVDYAFTGSQKCLSAPPGLAPIAASLEARKAFTGKRGWYLDLARVAEHWERGGYHHTTPVLLHYA
LLEALDLVLEEGVAARERRAREVYAWVLEELKARGFRPYPKASPLPTVLVVRPPEGVDADRLVRALYAEGVAVAGGIGPT
RGQVLRLGLMGEGARREAYQAFLKALDRALALA
>Mature_353_residues
MLLLTPGPTPIPERVQKALLRPMRGHLDPEVLRVNRAIQERLAALFDPGEGALVAALAGSGSLGMEAGLANLDRGPVLVL
VNGAFSQRVAEMAALHGLDPEVLDFPPGEPVDPEAVARALKRRRYRMVALVHGETSTGVLNPAEAIGALAKEAGALFFLD
AVTTLGMLPFSMRAMGVDYAFTGSQKCLSAPPGLAPIAASLEARKAFTGKRGWYLDLARVAEHWERGGYHHTTPVLLHYA
LLEALDLVLEEGVAARERRAREVYAWVLEELKARGFRPYPKASPLPTVLVVRPPEGVDADRLVRALYAEGVAVAGGIGPT
RGQVLRLGLMGEGARREAYQAFLKALDRALALA

Specific function: Could encode ureidoglycolase or L-alanine:glyoxylate aminotransferase, or perhaps both activities [H]

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=362, Percent_Identity=33.9779005524862, Blast_Score=179, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI17536281, Length=362, Percent_Identity=30.3867403314917, Blast_Score=184, Evalue=5e-47,
Organism=Saccharomyces cerevisiae, GI6321079, Length=364, Percent_Identity=32.1428571428571, Blast_Score=137, Evalue=2e-33,
Organism=Drosophila melanogaster, GI17530823, Length=363, Percent_Identity=32.5068870523416, Blast_Score=173, Evalue=1e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: NA

Molecular weight: Translated: 37844; Mature: 37844

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLLTPGPTPIPERVQKALLRPMRGHLDPEVLRVNRAIQERLAALFDPGEGALVAALAGS
CEEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECC
GSLGMEAGLANLDRGPVLVLVNGAFSQRVAEMAALHGLDPEVLDFPPGEPVDPEAVARAL
CCCCHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHH
KRRRYRMVALVHGETSTGVLNPAEAIGALAKEAGALFFLDAVTTLGMLPFSMRAMGVDYA
HHHHEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHCCCEE
FTGSQKCLSAPPGLAPIAASLEARKAFTGKRGWYLDLARVAEHWERGGYHHTTPVLLHYA
ECCCCHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHCCCCCCCHHHHHHHH
LLEALDLVLEEGVAARERRAREVYAWVLEELKARGFRPYPKASPLPTVLVVRPPEGVDAD
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCHH
RLVRALYAEGVAVAGGIGPTRGQVLRLGLMGEGARREAYQAFLKALDRALALA
HHHHHHHHCCEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLLLTPGPTPIPERVQKALLRPMRGHLDPEVLRVNRAIQERLAALFDPGEGALVAALAGS
CEEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECC
GSLGMEAGLANLDRGPVLVLVNGAFSQRVAEMAALHGLDPEVLDFPPGEPVDPEAVARAL
CCCCHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHH
KRRRYRMVALVHGETSTGVLNPAEAIGALAKEAGALFFLDAVTTLGMLPFSMRAMGVDYA
HHHHEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHCCCEE
FTGSQKCLSAPPGLAPIAASLEARKAFTGKRGWYLDLARVAEHWERGGYHHTTPVLLHYA
ECCCCHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHCCCCCCCHHHHHHHH
LLEALDLVLEEGVAARERRAREVYAWVLEELKARGFRPYPKASPLPTVLVVRPPEGVDAD
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCHH
RLVRALYAEGVAVAGGIGPTRGQVLRLGLMGEGARREAYQAFLKALDRALALA
HHHHHHHHCCEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 11344136 [H]