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The map label for this gene is yycG [H]

Identifier: 55980113

GI number: 55980113

Start: 140483

End: 141376

Strand: Reverse

Name: yycG [H]

Synonym: TTHA0144

Alternate gene names: 55980113

Gene position: 141376-140483 (Counterclockwise)

Preceding gene: 55980114

Following gene: 55980112

Centisome position: 7.64

GC content: 73.71

Gene sequence:

>894_bases
GTGAGCCCCGAGGCCTGGACCCTTCCTTGGGAGGAGGCCCGGGAGGGGCTCGTTGTGCACCGGGACAGGCAGGTGGTCTA
CCTCAACCCCGCGGCGGCGGAGCTTCTTGCGGTGGACCGGGAGAAGGTCCGGGGCCTGCCCCTCATCCTGGCCCTGCGGG
ACCACCGCCTGGAGGCCTTGGCCCTAGAGGGGGGAGAGGCGGTGTTGGAGGTGCGGGGCCGGGTTCTTTCGGCGCGGGCC
CGCCCGGGCCTCCTCTACCTCCTGGACGTGACCGAGGCCCGGCGCCGGGGCCTCGAGGCGGAGGAGGCCGGGGCTCTCCT
CGCTCACGAGTTCCGCACCCCCCTCGCCGGGATGGCCGTCCTCCTCCGGGCCCTCGCCCCCAAGGACCCCCGGGAGGCCC
AGGTCCTGGACCTCCTCAAGAAGGAGGTGGCCCGGCTCACCCGGCTGGTGGAAAGCCTCGCCCACCTCCGGCCCGGCCGC
CGGGAGGCCTTCGCCCTGGAGGACCTCTGGCTCCGCCTTTCCGCCCTCATGCAGGACCGCCTTCGGGGAAGGCGGGTGGA
GGTGGCCCTGGGGCACCGGGTGGAGGCGGACCCCGAGGCCCTCCTCCAGATCCTCCTCAACCTCCTGGACAACGCCCTCA
AGTACGGCCAAGACCCCATCCGCCTTCTGAGCCGGGTCCGGGGCGGCCGGCTCTACCTAGAGGTGCGGGACCGGGGGGCG
CCCCTTCCCGACTACGAGGGCCTTTTCCAGCCGGGTCGGCGGGGAGGGGAGGGCTCGGGCCAGGGGCTCGGCCTCTACCT
GGTGCGCCGCCTGGCCCAGGGCCTGGGCGGGGGGGCTTACGCCTTGCGCGAAGGGGAGGAGAACGTCTTCGGCGTCTGGC
TCCCCGTAGACTGA

Upstream 100 bases:

>100_bases
AGCACGTCCTCCAGCTCAGGGAGAAGCTCGGGGAGGACCCCAAGGCCCCCCGCTTCCTGGAGACGGTGCGGGGCGTGGGG
TACCGCTTCCGGGAGGAGGC

Downstream 100 bases:

>100_bases
GGAAAGGAGGCGGCATGCGGGAAGCGTTGGACCGAGCCTTGAACCAGCTTCTGGAAGAGAGCCTGAGGATGCTCTCCCTG
GTGCGGGAGATGACCCAGGA

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MSPEAWTLPWEEAREGLVVHRDRQVVYLNPAAAELLAVDREKVRGLPLILALRDHRLEALALEGGEAVLEVRGRVLSARA
RPGLLYLLDVTEARRRGLEAEEAGALLAHEFRTPLAGMAVLLRALAPKDPREAQVLDLLKKEVARLTRLVESLAHLRPGR
REAFALEDLWLRLSALMQDRLRGRRVEVALGHRVEADPEALLQILLNLLDNALKYGQDPIRLLSRVRGGRLYLEVRDRGA
PLPDYEGLFQPGRRGGEGSGQGLGLYLVRRLAQGLGGGAYALREGEENVFGVWLPVD

Sequences:

>Translated_297_residues
MSPEAWTLPWEEAREGLVVHRDRQVVYLNPAAAELLAVDREKVRGLPLILALRDHRLEALALEGGEAVLEVRGRVLSARA
RPGLLYLLDVTEARRRGLEAEEAGALLAHEFRTPLAGMAVLLRALAPKDPREAQVLDLLKKEVARLTRLVESLAHLRPGR
REAFALEDLWLRLSALMQDRLRGRRVEVALGHRVEADPEALLQILLNLLDNALKYGQDPIRLLSRVRGGRLYLEVRDRGA
PLPDYEGLFQPGRRGGEGSGQGLGLYLVRRLAQGLGGGAYALREGEENVFGVWLPVD
>Mature_296_residues
SPEAWTLPWEEAREGLVVHRDRQVVYLNPAAAELLAVDREKVRGLPLILALRDHRLEALALEGGEAVLEVRGRVLSARAR
PGLLYLLDVTEARRRGLEAEEAGALLAHEFRTPLAGMAVLLRALAPKDPREAQVLDLLKKEVARLTRLVESLAHLRPGRR
EAFALEDLWLRLSALMQDRLRGRRVEVALGHRVEADPEALLQILLNLLDNALKYGQDPIRLLSRVRGGRLYLEVRDRGAP
LPDYEGLFQPGRRGGEGSGQGLGLYLVRRLAQGLGGGAYALREGEENVFGVWLPVD

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: COG5002

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI87082128, Length=215, Percent_Identity=30.6976744186047, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1790436, Length=207, Percent_Identity=28.9855072463768, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790300, Length=328, Percent_Identity=28.0487804878049, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI48994928, Length=322, Percent_Identity=26.0869565217391, Blast_Score=64, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 33022; Mature: 32891

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: PS50109 HIS_KIN ; PS00213 LIPOCALIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPEAWTLPWEEAREGLVVHRDRQVVYLNPAAAELLAVDREKVRGLPLILALRDHRLEAL
CCCCCCCCCHHHHHCCCEEEECCEEEEECCHHHHHHHHHHHHHCCCEEEEEEHHCCEEEE
ALEGGEAVLEVRGRVLSARARPGLLYLLDVTEARRRGLEAEEAGALLAHEFRTPLAGMAV
EECCCHHHHHHHHHHHHHCCCCCEEEEEECHHHHHCCCCHHHHHHHHHHHHCCCHHHHHH
LLRALAPKDPREAQVLDLLKKEVARLTRLVESLAHLRPGRREAFALEDLWLRLSALMQDR
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
LRGRRVEVALGHRVEADPEALLQILLNLLDNALKYGQDPIRLLSRVRGGRLYLEVRDRGA
HCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEEECCCCC
PLPDYEGLFQPGRRGGEGSGQGLGLYLVRRLAQGLGGGAYALREGEENVFGVWLPVD
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEEECC
>Mature Secondary Structure 
SPEAWTLPWEEAREGLVVHRDRQVVYLNPAAAELLAVDREKVRGLPLILALRDHRLEAL
CCCCCCCCHHHHHCCCEEEECCEEEEECCHHHHHHHHHHHHHCCCEEEEEEHHCCEEEE
ALEGGEAVLEVRGRVLSARARPGLLYLLDVTEARRRGLEAEEAGALLAHEFRTPLAGMAV
EECCCHHHHHHHHHHHHHCCCCCEEEEEECHHHHHCCCCHHHHHHHHHHHHCCCHHHHHH
LLRALAPKDPREAQVLDLLKKEVARLTRLVESLAHLRPGRREAFALEDLWLRLSALMQDR
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
LRGRRVEVALGHRVEADPEALLQILLNLLDNALKYGQDPIRLLSRVRGGRLYLEVRDRGA
HCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEEECCCCC
PLPDYEGLFQPGRRGGEGSGQGLGLYLVRRLAQGLGGGAYALREGEENVFGVWLPVD
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]