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The map label for this gene is regX3 [H]

Identifier: 55980114

GI number: 55980114

Start: 141373

End: 142044

Strand: Reverse

Name: regX3 [H]

Synonym: TTHA0145

Alternate gene names: 55980114

Gene position: 142044-141373 (Counterclockwise)

Preceding gene: 55980115

Following gene: 55980113

Centisome position: 7.68

GC content: 74.26

Gene sequence:

>672_bases
GTGGCCACCCTGCTTCTGGTGGAGGACGAGCCCAGCCTGCGCCTGGGGTTGCGGCTGGCCCTCGAGGGGGCGGGGCACCG
GGTTTTGGAGGCGGCCACCGCGCAGGAGGCCTGGCCCCTCCTGCGGGAGGCGGAGCTCGTGGTCCTGGACTGGATGCTCC
CCGACGAGCCCGGGGTGCGCCTCCTGGACCGGATGCGCCAGGGCCCCTACGAGTCCCTCCCCGTCCTGATGCTCACGGCC
CGGGCCGGGGTGCGGGACCGGGTGGAGGGGCTTTCCCGCGGGGCCGACGACTACCTGGTGAAGCCCTTCGCCGTGGAGGA
GCTTCTGGCCCGCCTCGAGGCCCTCTTGCGCCGGGCGGGGAAGCGCAAGGTGCTGAGGCGGGGCCCCCTCCTCCTGGACC
TGGAGCGGATGGAGGCCCGCCTGGAAGGCAACCCCCTCCCCCTCACCCGGCGGGAGTTTGCCCTCCTCGCCTACCTGGCG
GAGCGGCCGGGCCGGGTCTGCACCCGGGAAGAGCTCCTGGAGGCGGTCTGGGGCCCGGACTACCTCGGCACCCCCAGGAC
CGTGGACCAGCACGTCCTCCAGCTCAGGGAGAAGCTCGGGGAGGACCCCAAGGCCCCCCGCTTCCTGGAGACGGTGCGGG
GCGTGGGGTACCGCTTCCGGGAGGAGGCGTGA

Upstream 100 bases:

>100_bases
GGGTGCGGGAACTGCTCTGACCCGGGCCAAAGCCGGCCTTTCCGGGGCCCAGAAGAAGCGCCTGACACTCCCCTGACCCG
GCCCCCGCTAGACTGGGGGT

Downstream 100 bases:

>100_bases
GCCCCGAGGCCTGGACCCTTCCTTGGGAGGAGGCCCGGGAGGGGCTCGTTGTGCACCGGGACAGGCAGGTGGTCTACCTC
AACCCCGCGGCGGCGGAGCT

Product: phosphate regulon transcriptional regulatory protein PhoB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 222

Protein sequence:

>223_residues
MATLLLVEDEPSLRLGLRLALEGAGHRVLEAATAQEAWPLLREAELVVLDWMLPDEPGVRLLDRMRQGPYESLPVLMLTA
RAGVRDRVEGLSRGADDYLVKPFAVEELLARLEALLRRAGKRKVLRRGPLLLDLERMEARLEGNPLPLTRREFALLAYLA
ERPGRVCTREELLEAVWGPDYLGTPRTVDQHVLQLREKLGEDPKAPRFLETVRGVGYRFREEA

Sequences:

>Translated_223_residues
MATLLLVEDEPSLRLGLRLALEGAGHRVLEAATAQEAWPLLREAELVVLDWMLPDEPGVRLLDRMRQGPYESLPVLMLTA
RAGVRDRVEGLSRGADDYLVKPFAVEELLARLEALLRRAGKRKVLRRGPLLLDLERMEARLEGNPLPLTRREFALLAYLA
ERPGRVCTREELLEAVWGPDYLGTPRTVDQHVLQLREKLGEDPKAPRFLETVRGVGYRFREEA
>Mature_222_residues
ATLLLVEDEPSLRLGLRLALEGAGHRVLEAATAQEAWPLLREAELVVLDWMLPDEPGVRLLDRMRQGPYESLPVLMLTAR
AGVRDRVEGLSRGADDYLVKPFAVEELLARLEALLRRAGKRKVLRRGPLLLDLERMEARLEGNPLPLTRREFALLAYLAE
RPGRVCTREELLEAVWGPDYLGTPRTVDQHVLQLREKLGEDPKAPRFLETVRGVGYRFREEA

Specific function: Part of the two-component regulatory system senX3/regX3. Once phosphorylated by senX3, activates the expression of several operons/genes involved in phosphate assimilation and metabolism, such as pstSCAB, phnDCE, and phoA [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=38.6666666666667, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1786599, Length=222, Percent_Identity=39.6396396396396, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI1790552, Length=218, Percent_Identity=42.2018348623853, Blast_Score=134, Evalue=4e-33,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=37.10407239819, Blast_Score=130, Evalue=5e-32,
Organism=Escherichia coli, GI1788394, Length=226, Percent_Identity=35.8407079646018, Blast_Score=130, Evalue=9e-32,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=37.8854625550661, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI1789402, Length=224, Percent_Identity=40.625, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1786784, Length=219, Percent_Identity=36.986301369863, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI87082012, Length=219, Percent_Identity=35.1598173515982, Blast_Score=120, Evalue=7e-29,
Organism=Escherichia coli, GI1790860, Length=227, Percent_Identity=37.8854625550661, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=37.719298245614, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=31.8777292576419, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1787229, Length=230, Percent_Identity=30.8695652173913, Blast_Score=90, Evalue=9e-20,
Organism=Escherichia coli, GI145693140, Length=241, Percent_Identity=30.7053941908714, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25316; Mature: 25185

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATLLLVEDEPSLRLGLRLALEGAGHRVLEAATAQEAWPLLREAELVVLDWMLPDEPGVR
CCEEEEEECCCCCEEHHEEEECCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCHH
LLDRMRQGPYESLPVLMLTARAGVRDRVEGLSRGADDYLVKPFAVEELLARLEALLRRAG
HHHHHHCCCCCCCCHHHEEHHCCHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHH
KRKVLRRGPLLLDLERMEARLEGNPLPLTRREFALLAYLAERPGRVCTREELLEAVWGPD
HHHHHHHCCCEEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCC
YLGTPRTVDQHVLQLREKLGEDPKAPRFLETVRGVGYRFREEA
CCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHCCCC
>Mature Secondary Structure 
ATLLLVEDEPSLRLGLRLALEGAGHRVLEAATAQEAWPLLREAELVVLDWMLPDEPGVR
CEEEEEECCCCCEEHHEEEECCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCHH
LLDRMRQGPYESLPVLMLTARAGVRDRVEGLSRGADDYLVKPFAVEELLARLEALLRRAG
HHHHHHCCCCCCCCHHHEEHHCCHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHH
KRKVLRRGPLLLDLERMEARLEGNPLPLTRREFALLAYLAERPGRVCTREELLEAVWGPD
HHHHHHHCCCEEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCC
YLGTPRTVDQHVLQLREKLGEDPKAPRFLETVRGVGYRFREEA
CCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA