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The map label for this gene is argK [C]

Identifier: 55980105

GI number: 55980105

Start: 133326

End: 134273

Strand: Reverse

Name: argK [C]

Synonym: TTHA0136

Alternate gene names: 55980105

Gene position: 134273-133326 (Counterclockwise)

Preceding gene: 55980106

Following gene: 55980101

Centisome position: 7.26

GC content: 72.26

Gene sequence:

>948_bases
ATGAGCATCCCCGAGGAGCTTTGGCGCCGCTTCCAGGAAGGGGACCCCAGGGCCTTGGCCCGGGCCTTGACCTTGGTGGA
GTCGGGCCACCCCGCAGGCCGGGAGCTTTTGAAGCGGGTCCGGGGGAAAGGGCGGGCCAAGGTGGTGGGCGTGACGGGAA
GCCCCGGGGCGGGGAAGAGCACCCTGACCGACCGGCTCATCCTCGAGGCCCGGAAGCGGGGGGAGCGGGTGGCCGTCTTG
GCCGTGGACCCCTCCAGCCCCTTCAGCGGGGGGGCCATCCTCGGCGACCGGATCCGGATGATGCGCCACCACCAGGACCC
CGGGGTCTACATTCGCTCCATGGCCTCCCGGGGGGCCTTGGGTGGGCTGGCCGGGGCCACGGTGGCCGCCCTGAGCCTCC
TCGAGGCCTTCGGCTTTGACCGCATCTTCGTGGAGACGGTGGGGGTGGGGCAGAGCGAGGTGGACATCGCCCGGGTGGCG
GACACCACCCTGCTCGTCCTCACCCCGGCCGCGGGGGACGCGGTCCAAGCCTTCAAGGCCGGGGTCATGGAGATCGCCGA
CGTTTTCGCCGTCAACAAGTTTGACCTGCCCGGTGGGGAGCGGATCGTTCAGGAGCTCAAAAGCGCCTTGGAGCTCTCCC
CGCCCCGGCCCGGGGGGTGGCGCCCTCCCATCCACCCCACGGTGGCGGCCAGCGGCGAGGGGGTGGAGGCCCTCTTTGAG
AGCCTCGAGGCCCACCACCGCCACCTCGTGGAGCACGGGCTTTTGGAGGCACACCGCCTGGAGCGGGCCCGGTTTGAGGT
GGAGAGCGTCATCCAGGAGTGGGGCCGCCAAAGAACCCAGGGGGCGGGCGCCTTGGTGGCCCGGGTGGCCCGGGGGGAGC
TCACCCCCGAGGAGGCGGCCCTAGCCCTTCTTGGCCCGGGCCCGGAGGCGGAGGAGGGCGCGCTTTAG

Upstream 100 bases:

>100_bases
GGCCTTGCCCCGGGGGGTCCGGGTGGAGGTGGCCTGCGTGGCCCTGGCCGAGTAGGGGCACTCTTTTCTGCAAGGCGGCG
AAAACCCGTAGAATGGGCCC

Downstream 100 bases:

>100_bases
CATCTCCCGCTCGTTGGGGTAGGAGAGGCGTTCCAGCGCCTCGCTCGCCGGGAGGAAAAAGGCGTCCTCCACCTCCGTGA
GCTGGGGCCTGGGGGTGCCC

Product: LAO/AO transport system kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MSIPEELWRRFQEGDPRALARALTLVESGHPAGRELLKRVRGKGRAKVVGVTGSPGAGKSTLTDRLILEARKRGERVAVL
AVDPSSPFSGGAILGDRIRMMRHHQDPGVYIRSMASRGALGGLAGATVAALSLLEAFGFDRIFVETVGVGQSEVDIARVA
DTTLLVLTPAAGDAVQAFKAGVMEIADVFAVNKFDLPGGERIVQELKSALELSPPRPGGWRPPIHPTVAASGEGVEALFE
SLEAHHRHLVEHGLLEAHRLERARFEVESVIQEWGRQRTQGAGALVARVARGELTPEEAALALLGPGPEAEEGAL

Sequences:

>Translated_315_residues
MSIPEELWRRFQEGDPRALARALTLVESGHPAGRELLKRVRGKGRAKVVGVTGSPGAGKSTLTDRLILEARKRGERVAVL
AVDPSSPFSGGAILGDRIRMMRHHQDPGVYIRSMASRGALGGLAGATVAALSLLEAFGFDRIFVETVGVGQSEVDIARVA
DTTLLVLTPAAGDAVQAFKAGVMEIADVFAVNKFDLPGGERIVQELKSALELSPPRPGGWRPPIHPTVAASGEGVEALFE
SLEAHHRHLVEHGLLEAHRLERARFEVESVIQEWGRQRTQGAGALVARVARGELTPEEAALALLGPGPEAEEGAL
>Mature_314_residues
SIPEELWRRFQEGDPRALARALTLVESGHPAGRELLKRVRGKGRAKVVGVTGSPGAGKSTLTDRLILEARKRGERVAVLA
VDPSSPFSGGAILGDRIRMMRHHQDPGVYIRSMASRGALGGLAGATVAALSLLEAFGFDRIFVETVGVGQSEVDIARVAD
TTLLVLTPAAGDAVQAFKAGVMEIADVFAVNKFDLPGGERIVQELKSALELSPPRPGGWRPPIHPTVAASGEGVEALFES
LEAHHRHLVEHGLLEAHRLERARFEVESVIQEWGRQRTQGAGALVARVARGELTPEEAALALLGPGPEAEEGAL

Specific function: May have GTPase activity. May also bind and hydrolyze ATP. May function as chaperone [H]

COG id: COG1703

COG function: function code E; Putative periplasmic protein kinase ArgK and related GTPases of G3E family

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgK family [H]

Homologues:

Organism=Homo sapiens, GI26892295, Length=287, Percent_Identity=38.6759581881533, Blast_Score=177, Evalue=9e-45,
Organism=Escherichia coli, GI1789285, Length=280, Percent_Identity=35.7142857142857, Blast_Score=154, Evalue=7e-39,
Organism=Caenorhabditis elegans, GI71994271, Length=327, Percent_Identity=35.474006116208, Blast_Score=169, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI71994275, Length=220, Percent_Identity=38.6363636363636, Blast_Score=151, Evalue=5e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005129
- InterPro:   IPR003593 [H]

Pfam domain/function: PF03308 ArgK [H]

EC number: 2.7.-.- [C]

Molecular weight: Translated: 33524; Mature: 33393

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIPEELWRRFQEGDPRALARALTLVESGHPAGRELLKRVRGKGRAKVVGVTGSPGAGKS
CCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCH
TLTDRLILEARKRGERVAVLAVDPSSPFSGGAILGDRIRMMRHHQDPGVYIRSMASRGAL
HHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCC
GGLAGATVAALSLLEAFGFDRIFVETVGVGQSEVDIARVADTTLLVLTPAAGDAVQAFKA
CHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHCCCEEEEEECCCCHHHHHHHH
GVMEIADVFAVNKFDLPGGERIVQELKSALELSPPRPGGWRPPIHPTVAASGEGVEALFE
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
SLEAHHRHLVEHGLLEAHRLERARFEVESVIQEWGRQRTQGAGALVARVARGELTPEEAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHE
LALLGPGPEAEEGAL
EEEECCCCCCCCCCC
>Mature Secondary Structure 
SIPEELWRRFQEGDPRALARALTLVESGHPAGRELLKRVRGKGRAKVVGVTGSPGAGKS
CCHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCH
TLTDRLILEARKRGERVAVLAVDPSSPFSGGAILGDRIRMMRHHQDPGVYIRSMASRGAL
HHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCC
GGLAGATVAALSLLEAFGFDRIFVETVGVGQSEVDIARVADTTLLVLTPAAGDAVQAFKA
CHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHCCCEEEEEECCCCHHHHHHHH
GVMEIADVFAVNKFDLPGGERIVQELKSALELSPPRPGGWRPPIHPTVAASGEGVEALFE
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
SLEAHHRHLVEHGLLEAHRLERARFEVESVIQEWGRQRTQGAGALVARVARGELTPEEAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHE
LALLGPGPEAEEGAL
EEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Arg [C]

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]