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The map label for this gene is idnO [H]

Identifier: 55980102

GI number: 55980102

Start: 130031

End: 130738

Strand: Direct

Name: idnO [H]

Synonym: TTHA0133

Alternate gene names: 55980102

Gene position: 130031-130738 (Clockwise)

Preceding gene: 55980100

Following gene: 55980103

Centisome position: 7.03

GC content: 69.77

Gene sequence:

>708_bases
ATGTCACGGGACCTTCTGGGCCTCGAGGGGAAGATCGTCATGGTCACGGGCGCGGGCCGGGGGTTCGGGCGGGCCATCGC
CCACGGGTACGGGCGCAACGGGGCCACGGTCATCGCCGTGGACCCCGACGTGGAGCTCGCCACGGGGGTGGCCTCGGAGG
TGGAGGCCCTTGGGGCCACGGCCATCCCCATCCGCGGGGACATGAGCGTGGTGTTGGACGTGACCAGCACCTTTGAAAAA
GTGGAGGAGCTCTTCGGCCTCCTGGACGGCATCGTCCACGTGACCACCGCCGAGAGCAAGACGCCCTTCGTGGAGCTTTT
GGAGGGCGAGTGGTACGACCTCATGAGCCAGGACGTGAAGTCCAGCCTCTACGTCCTCCAGCAGGGGCTGCGCCACCTGG
CGGGGGGCGGGTTCGTGACCATCGTCCTGCCGCCCGCAGCCCGAATAGAGCCCCACACCGTCTCCGTGCGCAAGGCGGTG
GAGGGCCTCATTGAAGGGGCCACCCGCACCTTCCCCGGGGTGCGGGTGAACGGCGTGGTCCCCTCCCGCGACCCCGTGGG
CGACCCCTACGACCTGCCCCTGGTCCGGGCCGCCTTGGGCCTGGGGTCCATGGTCTCCGAGGGGATCCGGGGGGTGGTCC
TCGAGGTCCAGCTCCCCGAGCCCCCCTTGGAGTTTGAACCCTACGCCGCCTTGAGGGAGCTGCCATGA

Upstream 100 bases:

>100_bases
TTGGCGGCGTTGACGATGGCGTCCCCTTGGAACTCGGTGATGTCCCCTTGGACCACCCGGATGCGCGCCATGGCTTTATT
CTCCCTTACAATGGGCCGTG

Downstream 100 bases:

>100_bases
AGTGCCCCTACTGCGGCCACCCCGACACCCGGGTGGTGGACTCGAGGCCCTCCGACGAGGGCATGGCCATCCGCAGGCGG
CGGGAGTGCCCCTCCTGCGG

Product: short chain dehydrogenase/reductase family oxidoreductase

Products: NA

Alternate protein names: 5-keto-D-gluconate 5-reductase [H]

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MSRDLLGLEGKIVMVTGAGRGFGRAIAHGYGRNGATVIAVDPDVELATGVASEVEALGATAIPIRGDMSVVLDVTSTFEK
VEELFGLLDGIVHVTTAESKTPFVELLEGEWYDLMSQDVKSSLYVLQQGLRHLAGGGFVTIVLPPAARIEPHTVSVRKAV
EGLIEGATRTFPGVRVNGVVPSRDPVGDPYDLPLVRAALGLGSMVSEGIRGVVLEVQLPEPPLEFEPYAALRELP

Sequences:

>Translated_235_residues
MSRDLLGLEGKIVMVTGAGRGFGRAIAHGYGRNGATVIAVDPDVELATGVASEVEALGATAIPIRGDMSVVLDVTSTFEK
VEELFGLLDGIVHVTTAESKTPFVELLEGEWYDLMSQDVKSSLYVLQQGLRHLAGGGFVTIVLPPAARIEPHTVSVRKAV
EGLIEGATRTFPGVRVNGVVPSRDPVGDPYDLPLVRAALGLGSMVSEGIRGVVLEVQLPEPPLEFEPYAALRELP
>Mature_234_residues
SRDLLGLEGKIVMVTGAGRGFGRAIAHGYGRNGATVIAVDPDVELATGVASEVEALGATAIPIRGDMSVVLDVTSTFEKV
EELFGLLDGIVHVTTAESKTPFVELLEGEWYDLMSQDVKSSLYVLQQGLRHLAGGGFVTIVLPPAARIEPHTVSVRKAVE
GLIEGATRTFPGVRVNGVVPSRDPVGDPYDLPLVRAALGLGSMVSEGIRGVVLEVQLPEPPLEFEPYAALRELP

Specific function: Catalyzes a reversible reduction of 5-ketoglutanate to form D-gluconate. Dependent on NADP, almost inactive with NAD [H]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Escherichia coli, GI1790717, Length=247, Percent_Identity=24.6963562753036, Blast_Score=68, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.69 [H]

Molecular weight: Translated: 24864; Mature: 24733

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRDLLGLEGKIVMVTGAGRGFGRAIAHGYGRNGATVIAVDPDVELATGVASEVEALGAT
CCCCCCCCCCEEEEEEECCCCHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCE
AIPIRGDMSVVLDVTSTFEKVEELFGLLDGIVHVTTAESKTPFVELLEGEWYDLMSQDVK
EEECCCCCEEEEEHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHCCCHHHHHHHHHH
SSLYVLQQGLRHLAGGGFVTIVLPPAARIEPHTVSVRKAVEGLIEGATRTFPGVRVNGVV
HHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCC
PSRDPVGDPYDLPLVRAALGLGSMVSEGIRGVVLEVQLPEPPLEFEPYAALRELP
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHCCC
>Mature Secondary Structure 
SRDLLGLEGKIVMVTGAGRGFGRAIAHGYGRNGATVIAVDPDVELATGVASEVEALGAT
CCCCCCCCCEEEEEEECCCCHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCE
AIPIRGDMSVVLDVTSTFEKVEELFGLLDGIVHVTTAESKTPFVELLEGEWYDLMSQDVK
EEECCCCCEEEEEHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHCCCHHHHHHHHHH
SSLYVLQQGLRHLAGGGFVTIVLPPAARIEPHTVSVRKAVEGLIEGATRTFPGVRVNGVV
HHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCC
PSRDPVGDPYDLPLVRAALGLGSMVSEGIRGVVLEVQLPEPPLEFEPYAALRELP
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]