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The map label for this gene is recG [H]

Identifier: 55980024

GI number: 55980024

Start: 52922

End: 54457

Strand: Reverse

Name: recG [H]

Synonym: TTHA0055

Alternate gene names: 55980024

Gene position: 54457-52922 (Counterclockwise)

Preceding gene: 55980030

Following gene: 55980023

Centisome position: 2.94

GC content: 71.35

Gene sequence:

>1536_bases
GTGACGTGGGAGGAGCTGGAGGAACGCCTGGCCCGGGGGCAGGACGAGCGCACCCTCTTCCTGCCCCAGGACATCTCCCC
CGAGGACCTGGCCCGCTACGCCGCGGGCCTCGCCAACCACAAGGGGGGCACCCTCTTCCTGGGCGTGAGCCCCGAGGGCA
AGGTCCTGGGCGCCCAGGACCTCCACCCCCTGCAGGTGACCCACGCCCTCTTTGAGCTCACCCAAGGGCTCCTCCTCCCC
TACGTGGAGGTGGTGGAGGGGCCCTGGGGCCGGGTGCTCGCCCTCCACGTGCCCCAAAGCCCGGCGGCCATCGCCGTGGG
GACAGGGCGGGTGCCCTTCTGGGACGGGAGGCGCCTTTCGGAGCTCAAGGTGGGCCAGAGCCTGCCCGAGCCCGACTTCA
CCGCCCAGGTCCTGCCCGCGGCGAGCCTTTCCGACCTGGACCCGGTGGAGGTCCTGCGCTTGAGGCGCATCCTAGAGGAA
AGGGGAAGCGCCTTGGCCGCCCTCCCCGACCTGGAGCTCCTCTTTGCCCTGGGGCTCTTGGAGCGGGTGGAGGGGGAGGT
GCGCCCCACGGTGGCGGGCCTTCTCCTGGCGGGGACGTCCCTCGCCTTGAGGCGGCTTCTTCCCCAGGCGGAGGTGAGCT
ACTACTTCCACGAGACCGAGGAGGGCTACAGCTTCCGGGAGGACCTCCTCAGGCCCATCCCCGCCCTCCTGGAGCGCCTG
AAGGAACTCATCCAGGCGCGGAACCGGGTCCGTTTTCTCACCGTGGGGCTTTTCCGCCTCGAGGTCTGGGACTTTGACCA
GGAGGTCTACCGGGAGGCCCTGGTCAACGCCCTCGTCCACCGGGACTGGCGGAGCAAGGACGCCATCCAGGTCCACCACT
ACCGGGACCGGCTGGAGGTCTCCAACCCCGGCGGCTTCCCCCCCGGCATCACCCCGGAGAACGTCCTCCGCCACCCCCCC
AAAAGGCGGAACCCCCGCCTGGCCGAGGCCCTCTACCGCCTGGGCTACGTGGAGCGGGCGGGAAGCGGCGTGGACAAGAT
GTACCGCCTCCTCCTCAAGTACGGCAAGGAACCCCCGGAGTACCGCCTCTTCCCCGAGGCCCTGACCCTCGTCCTCTACA
ACCCCGAGCTGGACGAGGCCTTCGTGCGGGAGATCGCCGAGGCCCAGGAGCGGCTTGGAGGGTTCAGCCTGGACCACCTC
ATCGCCGTGGGGTACCTGCGCCGGGTGGGGGAGGCGGGCCTGGAGGAGCTCGCCCGGGCGCTCCAGCTTCCCGAGGAGGC
GGCGCGGCGGGTCCTTTCCCGCATGGAAAGGATGGGGCTTCTGCGCAAGGAGGGAGGGCGGTACCACCTGGCCCGGCGGG
ACCTTTTGGCGGAGCGGGCCCTCGCCCTCTTGGAGGCGCCCAGGCGCCGCCAGGAGGTGGAGCGGGTCCTCGGGCTTTCC
CGCAAAAGGGCCCTGGAGCTTCTCCGCCGCCTCATCCGGGAGGGCCGGGTGGAGAGGGTGGGCCGGGGGGCGGCCACCCG
CTACCGGAGGCGGTGA

Upstream 100 bases:

>100_bases
AAGTGTTCCGCGAAAATGGCACGTATGTCACTGATTTATTGAACAAACCTGCGACCGAGCCCCTCCCTCTTCTCCCCGGA
CGCCCCGTAAACTGGGCCCC

Downstream 100 bases:

>100_bases
TGCTCCATCTGGTCCTCTACCAGCCGGAGATCCCCCAAAACGCCGGGAACGTGGCCCGCACCGCGGCCGCCCTGGGATGG
CCCCTCCACCTCATCCGTCC

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 511; Mature: 510

Protein sequence:

>511_residues
MTWEELEERLARGQDERTLFLPQDISPEDLARYAAGLANHKGGTLFLGVSPEGKVLGAQDLHPLQVTHALFELTQGLLLP
YVEVVEGPWGRVLALHVPQSPAAIAVGTGRVPFWDGRRLSELKVGQSLPEPDFTAQVLPAASLSDLDPVEVLRLRRILEE
RGSALAALPDLELLFALGLLERVEGEVRPTVAGLLLAGTSLALRRLLPQAEVSYYFHETEEGYSFREDLLRPIPALLERL
KELIQARNRVRFLTVGLFRLEVWDFDQEVYREALVNALVHRDWRSKDAIQVHHYRDRLEVSNPGGFPPGITPENVLRHPP
KRRNPRLAEALYRLGYVERAGSGVDKMYRLLLKYGKEPPEYRLFPEALTLVLYNPELDEAFVREIAEAQERLGGFSLDHL
IAVGYLRRVGEAGLEELARALQLPEEAARRVLSRMERMGLLRKEGGRYHLARRDLLAERALALLEAPRRRQEVERVLGLS
RKRALELLRRLIREGRVERVGRGAATRYRRR

Sequences:

>Translated_511_residues
MTWEELEERLARGQDERTLFLPQDISPEDLARYAAGLANHKGGTLFLGVSPEGKVLGAQDLHPLQVTHALFELTQGLLLP
YVEVVEGPWGRVLALHVPQSPAAIAVGTGRVPFWDGRRLSELKVGQSLPEPDFTAQVLPAASLSDLDPVEVLRLRRILEE
RGSALAALPDLELLFALGLLERVEGEVRPTVAGLLLAGTSLALRRLLPQAEVSYYFHETEEGYSFREDLLRPIPALLERL
KELIQARNRVRFLTVGLFRLEVWDFDQEVYREALVNALVHRDWRSKDAIQVHHYRDRLEVSNPGGFPPGITPENVLRHPP
KRRNPRLAEALYRLGYVERAGSGVDKMYRLLLKYGKEPPEYRLFPEALTLVLYNPELDEAFVREIAEAQERLGGFSLDHL
IAVGYLRRVGEAGLEELARALQLPEEAARRVLSRMERMGLLRKEGGRYHLARRDLLAERALALLEAPRRRQEVERVLGLS
RKRALELLRRLIREGRVERVGRGAATRYRRR
>Mature_510_residues
TWEELEERLARGQDERTLFLPQDISPEDLARYAAGLANHKGGTLFLGVSPEGKVLGAQDLHPLQVTHALFELTQGLLLPY
VEVVEGPWGRVLALHVPQSPAAIAVGTGRVPFWDGRRLSELKVGQSLPEPDFTAQVLPAASLSDLDPVEVLRLRRILEER
GSALAALPDLELLFALGLLERVEGEVRPTVAGLLLAGTSLALRRLLPQAEVSYYFHETEEGYSFREDLLRPIPALLERLK
ELIQARNRVRFLTVGLFRLEVWDFDQEVYREALVNALVHRDWRSKDAIQVHHYRDRLEVSNPGGFPPGITPENVLRHPPK
RRNPRLAEALYRLGYVERAGSGVDKMYRLLLKYGKEPPEYRLFPEALTLVLYNPELDEAFVREIAEAQERLGGFSLDHLI
AVGYLRRVGEAGLEELARALQLPEEAARRVLSRMERMGLLRKEGGRYHLARRDLLAERALALLEAPRRRQEVERVLGLSR
KRALELLRRLIREGRVERVGRGAATRYRRR

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG2865

COG function: function code K; Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase ATP-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 58099; Mature: 57968

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTWEELEERLARGQDERTLFLPQDISPEDLARYAAGLANHKGGTLFLGVSPEGKVLGAQD
CCHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCEECCCC
LHPLQVTHALFELTQGLLLPYVEVVEGPWGRVLALHVPQSPAAIAVGTGRVPFWDGRRLS
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEECCCCCCCCCCCCHH
ELKVGQSLPEPDFTAQVLPAASLSDLDPVEVLRLRRILEERGSALAALPDLELLFALGLL
HHHHCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHCCEEECCCCHHHHHHHHHH
ERVEGEVRPTVAGLLLAGTSLALRRLLPQAEVSYYFHETEEGYSFREDLLRPIPALLERL
HHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
KELIQARNRVRFLTVGLFRLEVWDFDQEVYREALVNALVHRDWRSKDAIQVHHYRDRLEV
HHHHHHHCCEEEEEHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHCCC
SNPGGFPPGITPENVLRHPPKRRNPRLAEALYRLGYVERAGSGVDKMYRLLLKYGKEPPE
CCCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCC
YRLFPEALTLVLYNPELDEAFVREIAEAQERLGGFSLDHLIAVGYLRRVGEAGLEELARA
CEECHHHHEEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LQLPEEAARRVLSRMERMGLLRKEGGRYHLARRDLLAERALALLEAPRRRQEVERVLGLS
HCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCC
RKRALELLRRLIREGRVERVGRGAATRYRRR
HHHHHHHHHHHHHCCCHHHHCCCHHHHHCCC
>Mature Secondary Structure 
TWEELEERLARGQDERTLFLPQDISPEDLARYAAGLANHKGGTLFLGVSPEGKVLGAQD
CHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCEECCCC
LHPLQVTHALFELTQGLLLPYVEVVEGPWGRVLALHVPQSPAAIAVGTGRVPFWDGRRLS
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEECCCCCCCCCCCCHH
ELKVGQSLPEPDFTAQVLPAASLSDLDPVEVLRLRRILEERGSALAALPDLELLFALGLL
HHHHCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHCCEEECCCCHHHHHHHHHH
ERVEGEVRPTVAGLLLAGTSLALRRLLPQAEVSYYFHETEEGYSFREDLLRPIPALLERL
HHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
KELIQARNRVRFLTVGLFRLEVWDFDQEVYREALVNALVHRDWRSKDAIQVHHYRDRLEV
HHHHHHHCCEEEEEHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHCCC
SNPGGFPPGITPENVLRHPPKRRNPRLAEALYRLGYVERAGSGVDKMYRLLLKYGKEPPE
CCCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCC
YRLFPEALTLVLYNPELDEAFVREIAEAQERLGGFSLDHLIAVGYLRRVGEAGLEELARA
CEECHHHHEEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LQLPEEAARRVLSRMERMGLLRKEGGRYHLARRDLLAERALALLEAPRRRQEVERVLGLS
HCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCC
RKRALELLRRLIREGRVERVGRGAATRYRRR
HHHHHHHHHHHHHCCCHHHHCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9603897 [H]