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The map label for this gene is ispH [H]

Identifier: 55979984

GI number: 55979984

Start: 16106

End: 17128

Strand: Direct

Name: ispH [H]

Synonym: TTHA0015

Alternate gene names: 55979984

Gene position: 16106-17128 (Clockwise)

Preceding gene: 55979983

Following gene: 55979985

Centisome position: 0.87

GC content: 69.5

Gene sequence:

>1023_bases
ATGGGGGGGATGTCGGGGCTTCGGCGGGTCTACCTGGCCCGGCCCCGGGGCTTCTGCGCCGGGGTGGTGATGGCCATTGA
GGCGGTGGAGCGGTGGGCGGAGGCCCTAAAGGAAAAGGGAGAGCTCGTGGTCTACCACGAGATCGTCCACAACCGGGTGG
TGGTGGAGCGCCTCCAGGCCAAGGGGGTCCACTTCGTGGAGGACCTCGCCGAGGTGGAGAGGCTGAGGCGGGAAAGGCGC
CTCGCGGACACCGTGGTCTTCTCGGCCCACGGCCACCCGCCCGCCGTCCGCAGGCAGGCGGCGGAGATGGGCCTCACCGT
CCTGGACGCCACCTGCCCCCTGGTGACCAAGGTGCACACCGAGGCGAAACGCTACGCCAAGGAGGGGTACTGGATCCTCC
TCATCGGGGACTCCGCCGACCACCAGGAGATCAAGGGCACCTACGGGGAGGCCCCGGAGAGGACCATCCTGGTGGCGGTG
CACACCCACGTGGGCAAGGACCCCCGCCTGGCCGACCCCCGCACCGTGGAGGTGCCGGACCCCGAGCGGGTGGTGGTCCT
CACCCAGACCACCTTGAGCGTGGACGACACCCTGGCCACCATCGCCATCCTCAAAAAGCGCTTCCCCAAGCTGGTGGTCC
CCTCCCGCAAGGACCTCTGCTACGCCACCCAGAACCGCCAGGAGGCGGTGAAGCGGATCGCCCCCAAGGTGGAGGCCTTC
CTAGTCCTCACGAGCCCCCACTCCTCCAACGGGATGCGCCTTTTGGAGCTGGCCCAAAGCCTGGTGGGCCGGGCCTACCG
GCTGGAGCGCCCGGAGGAGCTTAGGCCCGAGTGGCTGGAGGGGGTGGAAAGCCTGGGGATCACCTCCGCCGCCAGCACCC
CCGAGGACCTGGTGCAGGGGGTGGTGGACCGCCTCAAGGCCCAAAACCCGGGGCTGGAGGTGGTGGAAGAAGGGGCGTGG
GAGACGATCGCCTTCCGCGAGCCCAAGCCCCTCTCCCCCGAGGAGGTCCTGAAGGGTGCTTGA

Upstream 100 bases:

>100_bases
GCGCGGAAGGCCCTCAGGCGGGCCCAGACCCCCTTCGTCCGGGAGGTGGCGGAAAGGATCCTCTCCCCCGCCACAGACCC
CGAGGCCCCGGGCCCGTAGA

Downstream 100 bases:

>100_bases
CCCGAGGCTTTCCGTGGCCCCCATGGTGGACCGCACCGACCGGCACTTCCGCTTTCTGGTGCGGCAGGTGAGCCTGGGGG
TGAGGCTCTACACGGAGATG

Product: LytB protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MGGMSGLRRVYLARPRGFCAGVVMAIEAVERWAEALKEKGELVVYHEIVHNRVVVERLQAKGVHFVEDLAEVERLRRERR
LADTVVFSAHGHPPAVRRQAAEMGLTVLDATCPLVTKVHTEAKRYAKEGYWILLIGDSADHQEIKGTYGEAPERTILVAV
HTHVGKDPRLADPRTVEVPDPERVVVLTQTTLSVDDTLATIAILKKRFPKLVVPSRKDLCYATQNRQEAVKRIAPKVEAF
LVLTSPHSSNGMRLLELAQSLVGRAYRLERPEELRPEWLEGVESLGITSAASTPEDLVQGVVDRLKAQNPGLEVVEEGAW
ETIAFREPKPLSPEEVLKGA

Sequences:

>Translated_340_residues
MGGMSGLRRVYLARPRGFCAGVVMAIEAVERWAEALKEKGELVVYHEIVHNRVVVERLQAKGVHFVEDLAEVERLRRERR
LADTVVFSAHGHPPAVRRQAAEMGLTVLDATCPLVTKVHTEAKRYAKEGYWILLIGDSADHQEIKGTYGEAPERTILVAV
HTHVGKDPRLADPRTVEVPDPERVVVLTQTTLSVDDTLATIAILKKRFPKLVVPSRKDLCYATQNRQEAVKRIAPKVEAF
LVLTSPHSSNGMRLLELAQSLVGRAYRLERPEELRPEWLEGVESLGITSAASTPEDLVQGVVDRLKAQNPGLEVVEEGAW
ETIAFREPKPLSPEEVLKGA
>Mature_339_residues
GGMSGLRRVYLARPRGFCAGVVMAIEAVERWAEALKEKGELVVYHEIVHNRVVVERLQAKGVHFVEDLAEVERLRRERRL
ADTVVFSAHGHPPAVRRQAAEMGLTVLDATCPLVTKVHTEAKRYAKEGYWILLIGDSADHQEIKGTYGEAPERTILVAVH
THVGKDPRLADPRTVEVPDPERVVVLTQTTLSVDDTLATIAILKKRFPKLVVPSRKDLCYATQNRQEAVKRIAPKVEAFL
VLTSPHSSNGMRLLELAQSLVGRAYRLERPEELRPEWLEGVESLGITSAASTPEDLVQGVVDRLKAQNPGLEVVEEGAWE
TIAFREPKPLSPEEVLKGA

Specific function: Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) [H]

COG id: COG0761

COG function: function code IM; Penicillin tolerance protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ispH family [H]

Homologues:

Organism=Escherichia coli, GI1786212, Length=326, Percent_Identity=43.8650306748466, Blast_Score=234, Evalue=5e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003451 [H]

Pfam domain/function: PF02401 LYTB [H]

EC number: =1.17.1.2 [H]

Molecular weight: Translated: 37794; Mature: 37663

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGMSGLRRVYLARPRGFCAGVVMAIEAVERWAEALKEKGELVVYHEIVHNRVVVERLQA
CCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHH
KGVHFVEDLAEVERLRRERRLADTVVFSAHGHPPAVRRQAAEMGLTVLDATCPLVTKVHT
CCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHCCCEEEECCCHHHHHHHH
EAKRYAKEGYWILLIGDSADHQEIKGTYGEAPERTILVAVHTHVGKDPRLADPRTVEVPD
HHHHHHHCCCEEEEECCCCCCHHHCCCCCCCCCCEEEEEEECCCCCCCCCCCCEEEECCC
PERVVVLTQTTLSVDDTLATIAILKKRFPKLVVPSRKDLCYATQNRQEAVKRIAPKVEAF
CCEEEEEEEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCHHHHHHHHCCCCEEE
LVLTSPHSSNGMRLLELAQSLVGRAYRLERPEELRPEWLEGVESLGITSAASTPEDLVQG
EEEECCCCCCCHHHHHHHHHHHHHHHHCCCCHHCCHHHHHHHHHCCCCCCCCCHHHHHHH
VVDRLKAQNPGLEVVEEGAWETIAFREPKPLSPEEVLKGA
HHHHHHCCCCCHHHHHCCCCCEEEECCCCCCCHHHHHCCC
>Mature Secondary Structure 
GGMSGLRRVYLARPRGFCAGVVMAIEAVERWAEALKEKGELVVYHEIVHNRVVVERLQA
CCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHH
KGVHFVEDLAEVERLRRERRLADTVVFSAHGHPPAVRRQAAEMGLTVLDATCPLVTKVHT
CCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHCCCEEEECCCHHHHHHHH
EAKRYAKEGYWILLIGDSADHQEIKGTYGEAPERTILVAVHTHVGKDPRLADPRTVEVPD
HHHHHHHCCCEEEEECCCCCCHHHCCCCCCCCCCEEEEEEECCCCCCCCCCCCEEEECCC
PERVVVLTQTTLSVDDTLATIAILKKRFPKLVVPSRKDLCYATQNRQEAVKRIAPKVEAF
CCEEEEEEEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCHHHHHHHHCCCCEEE
LVLTSPHSSNGMRLLELAQSLVGRAYRLERPEELRPEWLEGVESLGITSAASTPEDLVQG
EEEECCCCCCCHHHHHHHHHHHHHHHHCCCCHHCCHHHHHHHHHCCCCCCCCCHHHHHHH
VVDRLKAQNPGLEVVEEGAWETIAFREPKPLSPEEVLKGA
HHHHHHCCCCCHHHHHCCCCCEEEECCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA