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The map label for this gene is coxC [H]

Identifier: 54295720

GI number: 54295720

Start: 3210673

End: 3211542

Strand: Reverse

Name: coxC [H]

Synonym: lpl2808

Alternate gene names: 54295720

Gene position: 3211542-3210673 (Counterclockwise)

Preceding gene: 54295721

Following gene: 54295718

Centisome position: 95.99

GC content: 43.22

Gene sequence:

>870_bases
ATGGGAGCACACGGTACATATTATATTCCCAAACCCAGTCACTGGCCTTTGATTGGCTCAATAGGCTTGACCACTACACT
GGTTGGTGCAGCATGCTGGCTACATCATGACTGGTATGGCCCTTACGTATTTATAGCGGGCTTATGTATTTTGGTTGCAA
TGATGTTTGGCTGGTTTGGGCAAGTCATCTACGAAAACAGCAAAGGCCTATATGATTTGCAAGTTGATCGTTCATTTCGC
TGGGGTATGTGCTGGTTCATATTTTCTGAAGTATGCTTTTTCGGAGCCTTTTTCGGAGCCCTGTTTTTTGCAAGATATTG
GTCAGTCCCTCTTTTGGGTGGTGAGATGCATCCTATTACTCATTACACCTTATGGCCTGAGTTCAAAGCAGTTTGGCCCT
TGCTGAGTAATCCAAATAATCAGACTTTTGCCGGGGCTCATGAAGCCATGGGGGCTTGGGGTTTGGCTGCAATAAATACC
ATTATTTTATTAACTTCCGGGGTAACCATCACCTGGGCACATTGGGCTTTAAAATTAAGAAAGCGTACTCAATTGCTAAC
AGGTATGTCATTGACCATCGCTTTGGGCGTTTTGTTCTTGATGTTACAAAGCTATGAGTATCATGAAGCATATACGGAAA
TGAATTTAACGCTGGATGCAGGTATTTATGGTACTACCTTTTTCATGCTGACAGGATTCCATGGTTTGCACGTAACAATC
GGAACAATCATGCTTATCGTTATTCTGGTTCGTTGCAAGAAGGGTCATTTTACTCCTGAACGGCATTTTGCTTTCGAAGG
GGTTGCCTGGTATTGGCACTTTGTGGATGTGGTGTGGTTGTTCCTATTTGTCTTTGTCTATTGGCTATAG

Upstream 100 bases:

>100_bases
CTTGAAATCGTGACAATGCAATTCACGCTAGCCAAATATCAACGGTCTTTGAGTATCAGCCTTGGCTGAATGACTTATTG
TTACAGGAGATTAAAGCATA

Downstream 100 bases:

>100_bases
AGTTAACCTAATTCATCCTTTATTACAACCGGGTGTTGATAAGCAAGCCCGGTTGAAATTGAATACGAACAATTTCCATT
TTGTAAGTAAAGCAGTAATC

Product: cytochrome c oxidase, subunit III

Products: NA

Alternate protein names: Cytochrome aa3 subunit 3; Cytochrome c oxidase polypeptide III; Oxidase aa(3) subunit 3 [H]

Number of amino acids: Translated: 289; Mature: 288

Protein sequence:

>289_residues
MGAHGTYYIPKPSHWPLIGSIGLTTTLVGAACWLHHDWYGPYVFIAGLCILVAMMFGWFGQVIYENSKGLYDLQVDRSFR
WGMCWFIFSEVCFFGAFFGALFFARYWSVPLLGGEMHPITHYTLWPEFKAVWPLLSNPNNQTFAGAHEAMGAWGLAAINT
IILLTSGVTITWAHWALKLRKRTQLLTGMSLTIALGVLFLMLQSYEYHEAYTEMNLTLDAGIYGTTFFMLTGFHGLHVTI
GTIMLIVILVRCKKGHFTPERHFAFEGVAWYWHFVDVVWLFLFVFVYWL

Sequences:

>Translated_289_residues
MGAHGTYYIPKPSHWPLIGSIGLTTTLVGAACWLHHDWYGPYVFIAGLCILVAMMFGWFGQVIYENSKGLYDLQVDRSFR
WGMCWFIFSEVCFFGAFFGALFFARYWSVPLLGGEMHPITHYTLWPEFKAVWPLLSNPNNQTFAGAHEAMGAWGLAAINT
IILLTSGVTITWAHWALKLRKRTQLLTGMSLTIALGVLFLMLQSYEYHEAYTEMNLTLDAGIYGTTFFMLTGFHGLHVTI
GTIMLIVILVRCKKGHFTPERHFAFEGVAWYWHFVDVVWLFLFVFVYWL
>Mature_288_residues
GAHGTYYIPKPSHWPLIGSIGLTTTLVGAACWLHHDWYGPYVFIAGLCILVAMMFGWFGQVIYENSKGLYDLQVDRSFRW
GMCWFIFSEVCFFGAFFGALFFARYWSVPLLGGEMHPITHYTLWPEFKAVWPLLSNPNNQTFAGAHEAMGAWGLAAINTI
ILLTSGVTITWAHWALKLRKRTQLLTGMSLTIALGVLFLMLQSYEYHEAYTEMNLTLDAGIYGTTFFMLTGFHGLHVTIG
TIMLIVILVRCKKGHFTPERHFAFEGVAWYWHFVDVVWLFLFVFVYWL

Specific function: Cytochrome O Terminal Oxidase Complex Is The Component Of The Aerobic Respiratory Chain Of E.Coli That Predominates When Cells Are Grown At High Aeration. [C]

COG id: COG1845

COG function: function code C; Heme/copper-type cytochrome/quinol oxidase, subunit 3

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 3 family [H]

Homologues:

Organism=Homo sapiens, GI251831113, Length=283, Percent_Identity=39.5759717314488, Blast_Score=164, Evalue=7e-41,
Organism=Escherichia coli, GI1786633, Length=132, Percent_Identity=31.0606060606061, Blast_Score=68, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6226542, Length=285, Percent_Identity=29.8245614035088, Blast_Score=105, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000298
- InterPro:   IPR013833 [H]

Pfam domain/function: PF00510 COX3 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 33131; Mature: 33000

Theoretical pI: Translated: 7.43; Mature: 7.43

Prosite motif: PS50253 COX3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAHGTYYIPKPSHWPLIGSIGLTTTLVGAACWLHHDWYGPYVFIAGLCILVAMMFGWFG
CCCCCCEECCCCCCCCEEECHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
QVIYENSKGLYDLQVDRSFRWGMCWFIFSEVCFFGAFFGALFFARYWSVPLLGGEMHPIT
HHHEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCE
HYTLWPEFKAVWPLLSNPNNQTFAGAHEAMGAWGLAAINTIILLTSGVTITWAHWALKLR
EEEECCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHEECCCEEEHHHHHHHHH
KRTQLLTGMSLTIALGVLFLMLQSYEYHEAYTEMNLTLDAGIYGTTFFMLTGFHGLHVTI
HHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHHEEEEEECCHHHHHHHHHHCCCHHHHHH
GTIMLIVILVRCKKGHFTPERHFAFEGVAWYWHFVDVVWLFLFVFVYWL
HHHHHHHHHHHHCCCCCCCCHHHEHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
GAHGTYYIPKPSHWPLIGSIGLTTTLVGAACWLHHDWYGPYVFIAGLCILVAMMFGWFG
CCCCCEECCCCCCCCEEECHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
QVIYENSKGLYDLQVDRSFRWGMCWFIFSEVCFFGAFFGALFFARYWSVPLLGGEMHPIT
HHHEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCE
HYTLWPEFKAVWPLLSNPNNQTFAGAHEAMGAWGLAAINTIILLTSGVTITWAHWALKLR
EEEECCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHEECCCEEEHHHHHHHHH
KRTQLLTGMSLTIALGVLFLMLQSYEYHEAYTEMNLTLDAGIYGTTFFMLTGFHGLHVTI
HHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHHEEEEEECCHHHHHHHHHHCCCHHHHHH
GTIMLIVILVRCKKGHFTPERHFAFEGVAWYWHFVDVVWLFLFVFVYWL
HHHHHHHHHHHHCCCCCCCCHHHEHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3019767; 2832167; 7651515 [H]