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The map label for this gene is pepN [H]

Identifier: 54295637

GI number: 54295637

Start: 3110723

End: 3113320

Strand: Reverse

Name: pepN [H]

Synonym: lpl2724

Alternate gene names: 54295637

Gene position: 3113320-3110723 (Counterclockwise)

Preceding gene: 54295642

Following gene: 54295636

Centisome position: 93.05

GC content: 41.69

Gene sequence:

>2598_bases
ATGACTATGCCAGACACGACCATTTATTTGAAGAATTATCAACCGCCTTCTTTTACAGTTGAGACTGTGGAATTGAATTT
TGATTTGTATGATGACCATGCTTTAGTGAACAGCACTCTTAAGTTAACACGTCAAAAGGATGGCGCTTTGCATTTGTATG
GCGAAGAGCTGGAATTAATTGCTTTGCATTTAAATGGGCGACCATTAGAACATGAGAAGTATGTGTTGACGAAAGATGCT
CTTACTATAGAGCAATGCCCGGATGAAATAGTACTTAACATTGTGACTCGCATTAAACCTCAAGAAAATACGCAATTATC
AGGACTTTATCGTTCTAACCATTTATTCTGTACTCAATGCGAAGCAGAAGGTTTCAGACGAATTACCTATTATCTTGATA
GACCCGATGTTTTGGCAACTTTTACTACACGAATTACTGCAGATAAAAAGCAATATCCGATTTTATTGTCTAACGGTAAT
TTAATGGATACCGGAGAAACCGCGGATGGACGTCATTGGGTGATTTGGGAGGATCCTTTCAAGAAGCCATCTTATTTATT
CGCTTTGGTAGCGGGCAATTTAGCTTGCGTTAGAGATAGTTTTGTTACTTGCTCCGGCAGGATTGTTGATTTACGGATTT
ATGTAGAACCGGGGAATGAAGACAAGTGCTCTCATGCCATGGAGTCATTAAAAAAAGCCATGAAATGGGATGAAGAGGTT
TATGGTCGTGAGTACGATTTAGATATTTATATGATAGTTGCGGTGAGCGATTTCAATATGGGAGCAATGGAAAACAAAGG
GTTGAATATATTTAATTCCAAATACATCCTCGCTCGCCCTGAAACCGCCACTGATCAAGATTTCGCAGATGTTGAAGGTG
TAGTAGGCCATGAGTATTTCCATAACTGGACAGGAAATCGTGTGACCTGTCGCGATTGGTTCCAGTTAAGTTTAAAAGAG
GGATTAACTGTATTCCGGGATCAGGAGTTTTCTCGGGATATGAATTCTCGTGATGTCAATCGGATTATGGACGTTAAGGT
ATTGCGCAGCGCTCAGTTTCCCGAGGACTCCGGGAGCATGGCGCATCCAGTAAGGCCGGAATCCTATCAGGAAATTAATA
ATTTTTATACGGCGACAGTATATAACAAAGGCGCGGAAGTGATTCGAATGCAACATACTTTGTTAGGCAAGGAGAGGTTT
CGGCGAGGCATGGATCTTTATTTCAAACGCCATGACGGCCATGCCGTAACCATTGATGATTTTGTTGCTGCCATGGAAGA
TGCCAATGGAGTTGACTTAACGCAATTCAAACTCTGGTATAGCCAGGCAGGGACACCTGAAGTGCGCGTTCTCAGCCATT
TTTCAGAAGGACGATTGGAAATTACCATGCAACAAAATTGTCCTCCTACGCCTGAGTGCCATGAGAAAAAGCCATTTCAT
ATCCCGGTTCGCATTGCATTATTTGATTTGAAAGGGGAAATGATTCCCATAGAAAACGAGCTTCTGGAGTTAAAGGAAAA
GGAGCAACGTTTTATTTTTTCTGGGCTAAATGAAAAACCTGTTGTCTCGCTATTAAGAGAATTCTCAGCCCCTGTGAAAA
TTTATGATGATCTGGATCAGGATGACTTGTTATTTTTATTGCGTTATGAAACGGATGGATATGCCAAGTGGGATGCGGCA
CAACGCCTGGTTCTTAACTGTCTCAATGAAAACTTGAAATTGCCAGCCAGTGAATGGCAAGTCTCTAAAACTCTTGTTGC
TGCCTTTCAGCATGTTCTGCTTGATGACTCTCTTGATATGGATCTCAGGGCAGAGTTGTTGACACCTCCAGGATTTGAAG
AAGTGGCAGCTACCATGAAATGGGTTGATGTCAGCAAGGTTGAATCAGTGCGAGATTATTTCCGTCAACAATTGGGATTG
GGCTTATACACAGAGGCGTCTGATCTTTATAAAGAATTATGGGAAGTAGAAGATCATCGCATGCATGGCCAAGCTTATGG
ACGCAGAAAATTAAGAAATGTTTGTTTATGGTTGATGATGAAAGCGAAAGAATCAGATGCTTTAGAATTATGCCGAGAAC
AATTCAAGGATTCTCGTACCATGACGGATCAAATTGCAAGTTGCAGCTTGCTAGTCAATTGCTCCAGAGAATCTCACCGA
AATGAAGCCATAGAAGGATTTTATAAACAATGGTCTCATAATGAATTGGTACTGGATAAGTGGTTTGCGATGCAAGCGGC
ATGTGAGTTACCAGGCACATTGGGTCATGTCAAAAAACTAACTCAACATCCCGCTTTTTGTATTAAGAATCCGAATAAAG
TGCGGGCATTGGTTGGCGCTTTTTGTATGGCTAACCCCAGAAACTTCCATGCGTTGGATAGCAGCGGATATGCCTTTTTA
AGTGAGGTATTGATTAAGCTCGACACACTAAATCCTCAAATCGCCGCACGCTTGGCTACGCCTTTTACGCGTTGGCGAAG
TTATGATGAACCAAGACAAAAGTTAATACAGAACCAGTTGGAGCAGCTTACAAAACTGGATTTGTCGCGGGATTTGCGCG
AGGTTGTAGATAAGAGTCTGATTGTTGAGGAAAAATAG

Upstream 100 bases:

>100_bases
TAAAAGCAAAAATTACTTCTTTTAATTCATAGTATAGTAGACTAACCACTTAATTAAATACATAAATCAATAAACTTATT
CGTTTTTTTTATAGGAAGCA

Downstream 100 bases:

>100_bases
AATGAATTAAAGTCAGGACTTACTATAAACCCAATCTCTTTGTTAAAAAAAGTTTTTAATTCGGTCATTTAGTTTATCTA
AACTCCCTCATTAAAAACAT

Product: aminopeptidase N

Products: NA

Alternate protein names: Alpha-aminoacylpeptide hydrolase [H]

Number of amino acids: Translated: 865; Mature: 864

Protein sequence:

>865_residues
MTMPDTTIYLKNYQPPSFTVETVELNFDLYDDHALVNSTLKLTRQKDGALHLYGEELELIALHLNGRPLEHEKYVLTKDA
LTIEQCPDEIVLNIVTRIKPQENTQLSGLYRSNHLFCTQCEAEGFRRITYYLDRPDVLATFTTRITADKKQYPILLSNGN
LMDTGETADGRHWVIWEDPFKKPSYLFALVAGNLACVRDSFVTCSGRIVDLRIYVEPGNEDKCSHAMESLKKAMKWDEEV
YGREYDLDIYMIVAVSDFNMGAMENKGLNIFNSKYILARPETATDQDFADVEGVVGHEYFHNWTGNRVTCRDWFQLSLKE
GLTVFRDQEFSRDMNSRDVNRIMDVKVLRSAQFPEDSGSMAHPVRPESYQEINNFYTATVYNKGAEVIRMQHTLLGKERF
RRGMDLYFKRHDGHAVTIDDFVAAMEDANGVDLTQFKLWYSQAGTPEVRVLSHFSEGRLEITMQQNCPPTPECHEKKPFH
IPVRIALFDLKGEMIPIENELLELKEKEQRFIFSGLNEKPVVSLLREFSAPVKIYDDLDQDDLLFLLRYETDGYAKWDAA
QRLVLNCLNENLKLPASEWQVSKTLVAAFQHVLLDDSLDMDLRAELLTPPGFEEVAATMKWVDVSKVESVRDYFRQQLGL
GLYTEASDLYKELWEVEDHRMHGQAYGRRKLRNVCLWLMMKAKESDALELCREQFKDSRTMTDQIASCSLLVNCSRESHR
NEAIEGFYKQWSHNELVLDKWFAMQAACELPGTLGHVKKLTQHPAFCIKNPNKVRALVGAFCMANPRNFHALDSSGYAFL
SEVLIKLDTLNPQIAARLATPFTRWRSYDEPRQKLIQNQLEQLTKLDLSRDLREVVDKSLIVEEK

Sequences:

>Translated_865_residues
MTMPDTTIYLKNYQPPSFTVETVELNFDLYDDHALVNSTLKLTRQKDGALHLYGEELELIALHLNGRPLEHEKYVLTKDA
LTIEQCPDEIVLNIVTRIKPQENTQLSGLYRSNHLFCTQCEAEGFRRITYYLDRPDVLATFTTRITADKKQYPILLSNGN
LMDTGETADGRHWVIWEDPFKKPSYLFALVAGNLACVRDSFVTCSGRIVDLRIYVEPGNEDKCSHAMESLKKAMKWDEEV
YGREYDLDIYMIVAVSDFNMGAMENKGLNIFNSKYILARPETATDQDFADVEGVVGHEYFHNWTGNRVTCRDWFQLSLKE
GLTVFRDQEFSRDMNSRDVNRIMDVKVLRSAQFPEDSGSMAHPVRPESYQEINNFYTATVYNKGAEVIRMQHTLLGKERF
RRGMDLYFKRHDGHAVTIDDFVAAMEDANGVDLTQFKLWYSQAGTPEVRVLSHFSEGRLEITMQQNCPPTPECHEKKPFH
IPVRIALFDLKGEMIPIENELLELKEKEQRFIFSGLNEKPVVSLLREFSAPVKIYDDLDQDDLLFLLRYETDGYAKWDAA
QRLVLNCLNENLKLPASEWQVSKTLVAAFQHVLLDDSLDMDLRAELLTPPGFEEVAATMKWVDVSKVESVRDYFRQQLGL
GLYTEASDLYKELWEVEDHRMHGQAYGRRKLRNVCLWLMMKAKESDALELCREQFKDSRTMTDQIASCSLLVNCSRESHR
NEAIEGFYKQWSHNELVLDKWFAMQAACELPGTLGHVKKLTQHPAFCIKNPNKVRALVGAFCMANPRNFHALDSSGYAFL
SEVLIKLDTLNPQIAARLATPFTRWRSYDEPRQKLIQNQLEQLTKLDLSRDLREVVDKSLIVEEK
>Mature_864_residues
TMPDTTIYLKNYQPPSFTVETVELNFDLYDDHALVNSTLKLTRQKDGALHLYGEELELIALHLNGRPLEHEKYVLTKDAL
TIEQCPDEIVLNIVTRIKPQENTQLSGLYRSNHLFCTQCEAEGFRRITYYLDRPDVLATFTTRITADKKQYPILLSNGNL
MDTGETADGRHWVIWEDPFKKPSYLFALVAGNLACVRDSFVTCSGRIVDLRIYVEPGNEDKCSHAMESLKKAMKWDEEVY
GREYDLDIYMIVAVSDFNMGAMENKGLNIFNSKYILARPETATDQDFADVEGVVGHEYFHNWTGNRVTCRDWFQLSLKEG
LTVFRDQEFSRDMNSRDVNRIMDVKVLRSAQFPEDSGSMAHPVRPESYQEINNFYTATVYNKGAEVIRMQHTLLGKERFR
RGMDLYFKRHDGHAVTIDDFVAAMEDANGVDLTQFKLWYSQAGTPEVRVLSHFSEGRLEITMQQNCPPTPECHEKKPFHI
PVRIALFDLKGEMIPIENELLELKEKEQRFIFSGLNEKPVVSLLREFSAPVKIYDDLDQDDLLFLLRYETDGYAKWDAAQ
RLVLNCLNENLKLPASEWQVSKTLVAAFQHVLLDDSLDMDLRAELLTPPGFEEVAATMKWVDVSKVESVRDYFRQQLGLG
LYTEASDLYKELWEVEDHRMHGQAYGRRKLRNVCLWLMMKAKESDALELCREQFKDSRTMTDQIASCSLLVNCSRESHRN
EAIEGFYKQWSHNELVLDKWFAMQAACELPGTLGHVKKLTQHPAFCIKNPNKVRALVGAFCMANPRNFHALDSSGYAFLS
EVLIKLDTLNPQIAARLATPFTRWRSYDEPRQKLIQNQLEQLTKLDLSRDLREVVDKSLIVEEK

Specific function: Aminopeptidase N is involved in the degradation of intracellular peptides generated by protein breakdown during normal growth as well as in response to nutrient starvation [H]

COG id: COG0308

COG function: function code E; Aminopeptidase N

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M1 family [H]

Homologues:

Organism=Homo sapiens, GI158937236, Length=411, Percent_Identity=27.4939172749392, Blast_Score=134, Evalue=4e-31,
Organism=Homo sapiens, GI132814467, Length=399, Percent_Identity=26.5664160401003, Blast_Score=119, Evalue=1e-26,
Organism=Homo sapiens, GI310123622, Length=331, Percent_Identity=28.7009063444109, Blast_Score=115, Evalue=2e-25,
Organism=Homo sapiens, GI61742777, Length=416, Percent_Identity=25.2403846153846, Blast_Score=115, Evalue=3e-25,
Organism=Homo sapiens, GI61742775, Length=416, Percent_Identity=25.2403846153846, Blast_Score=115, Evalue=3e-25,
Organism=Homo sapiens, GI310133497, Length=331, Percent_Identity=28.7009063444109, Blast_Score=113, Evalue=7e-25,
Organism=Homo sapiens, GI194306629, Length=425, Percent_Identity=25.1764705882353, Blast_Score=103, Evalue=7e-22,
Organism=Homo sapiens, GI11641261, Length=425, Percent_Identity=25.1764705882353, Blast_Score=103, Evalue=7e-22,
Organism=Homo sapiens, GI94818891, Length=375, Percent_Identity=25.0666666666667, Blast_Score=96, Evalue=2e-19,
Organism=Homo sapiens, GI94818901, Length=374, Percent_Identity=25.1336898395722, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI7019561, Length=387, Percent_Identity=27.390180878553, Blast_Score=90, Evalue=1e-17,
Organism=Homo sapiens, GI157266300, Length=422, Percent_Identity=23.2227488151659, Blast_Score=83, Evalue=1e-15,
Organism=Homo sapiens, GI194239713, Length=359, Percent_Identity=26.1838440111421, Blast_Score=81, Evalue=4e-15,
Organism=Escherichia coli, GI1787163, Length=877, Percent_Identity=48.5746864310148, Blast_Score=809, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71989076, Length=535, Percent_Identity=26.5420560747664, Blast_Score=144, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI71989071, Length=535, Percent_Identity=26.5420560747664, Blast_Score=144, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17569221, Length=351, Percent_Identity=29.3447293447293, Blast_Score=114, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17569225, Length=355, Percent_Identity=27.6056338028169, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI115533276, Length=370, Percent_Identity=28.6486486486486, Blast_Score=100, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI115533278, Length=370, Percent_Identity=28.6486486486486, Blast_Score=100, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI71990873, Length=340, Percent_Identity=26.1764705882353, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI193206928, Length=428, Percent_Identity=25, Blast_Score=93, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI193206926, Length=428, Percent_Identity=25, Blast_Score=92, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI133903840, Length=365, Percent_Identity=24.3835616438356, Blast_Score=90, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17565628, Length=394, Percent_Identity=26.9035532994924, Blast_Score=87, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17544504, Length=348, Percent_Identity=23.5632183908046, Blast_Score=84, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71984353, Length=432, Percent_Identity=23.3796296296296, Blast_Score=80, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI71984339, Length=432, Percent_Identity=22.9166666666667, Blast_Score=77, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI9755335, Length=384, Percent_Identity=27.8645833333333, Blast_Score=127, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6321837, Length=433, Percent_Identity=26.5588914549654, Blast_Score=125, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6324283, Length=476, Percent_Identity=22.6890756302521, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24655257, Length=427, Percent_Identity=27.4004683840749, Blast_Score=141, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24655274, Length=427, Percent_Identity=27.4004683840749, Blast_Score=141, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24655260, Length=427, Percent_Identity=27.4004683840749, Blast_Score=141, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24655265, Length=427, Percent_Identity=27.4004683840749, Blast_Score=141, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24655268, Length=427, Percent_Identity=27.4004683840749, Blast_Score=141, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24655252, Length=427, Percent_Identity=27.4004683840749, Blast_Score=141, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24646516, Length=364, Percent_Identity=27.4725274725275, Blast_Score=125, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24646518, Length=364, Percent_Identity=27.4725274725275, Blast_Score=125, Evalue=1e-28,
Organism=Drosophila melanogaster, GI21358341, Length=419, Percent_Identity=26.9689737470167, Blast_Score=125, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24646514, Length=364, Percent_Identity=27.7472527472527, Blast_Score=123, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24651016, Length=318, Percent_Identity=29.559748427673, Blast_Score=120, Evalue=4e-27,
Organism=Drosophila melanogaster, GI24646510, Length=412, Percent_Identity=26.6990291262136, Blast_Score=118, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24646512, Length=412, Percent_Identity=26.6990291262136, Blast_Score=117, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24651025, Length=340, Percent_Identity=26.7647058823529, Blast_Score=112, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24651023, Length=340, Percent_Identity=26.7647058823529, Blast_Score=112, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24651021, Length=340, Percent_Identity=26.7647058823529, Blast_Score=112, Evalue=1e-24,
Organism=Drosophila melanogaster, GI161078673, Length=426, Percent_Identity=24.6478873239437, Blast_Score=100, Evalue=7e-21,
Organism=Drosophila melanogaster, GI28571901, Length=426, Percent_Identity=24.6478873239437, Blast_Score=100, Evalue=8e-21,
Organism=Drosophila melanogaster, GI45550850, Length=374, Percent_Identity=25.9358288770053, Blast_Score=98, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24650973, Length=374, Percent_Identity=25.9358288770053, Blast_Score=98, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24648786, Length=407, Percent_Identity=24.5700245700246, Blast_Score=95, Evalue=2e-19,
Organism=Drosophila melanogaster, GI221379089, Length=364, Percent_Identity=23.6263736263736, Blast_Score=86, Evalue=8e-17,
Organism=Drosophila melanogaster, GI221330574, Length=436, Percent_Identity=25.4587155963303, Blast_Score=86, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24648790, Length=374, Percent_Identity=23.7967914438503, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28571792, Length=509, Percent_Identity=23.5756385068762, Blast_Score=81, Evalue=3e-15,
Organism=Drosophila melanogaster, GI45550350, Length=365, Percent_Identity=23.013698630137, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24585062, Length=365, Percent_Identity=23.013698630137, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24585064, Length=365, Percent_Identity=23.013698630137, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24585066, Length=365, Percent_Identity=23.013698630137, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001930
- InterPro:   IPR014782
- InterPro:   IPR012779 [H]

Pfam domain/function: PF01433 Peptidase_M1 [H]

EC number: =3.4.11.2 [H]

Molecular weight: Translated: 99889; Mature: 99758

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMPDTTIYLKNYQPPSFTVETVELNFDLYDDHALVNSTLKLTRQKDGALHLYGEELELI
CCCCCCEEEEECCCCCCEEEEEEEEEEEEECCHHHHHHHHHHEECCCCEEEEECCCEEEE
ALHLNGRPLEHEKYVLTKDALTIEQCPDEIVLNIVTRIKPQENTQLSGLYRSNHLFCTQC
EEEECCCCCCCCCEEEEECCEEHHHCCHHHHHHHHHHCCCCCCCEEEEEEECCCEEEEEC
EAEGFRRITYYLDRPDVLATFTTRITADKKQYPILLSNGNLMDTGETADGRHWVIWEDPF
CCCCCEEEEEEECCCCEEEEEEEEEECCCCCCCEEEECCCEEECCCCCCCCEEEEECCCC
KKPSYLFALVAGNLACVRDSFVTCSGRIVDLRIYVEPGNEDKCSHAMESLKKAMKWDEEV
CCCCEEEEEHHCCEEEEECCCEEECCEEEEEEEEEECCCCCHHHHHHHHHHHHHCCCHHH
YGREYDLDIYMIVAVSDFNMGAMENKGLNIFNSKYILARPETATDQDFADVEGVVGHEYF
CCCEECCEEEEEEEEECCCCCCCCCCCCEEECCEEEEECCCCCCCCCHHHHHHHHHHHHH
HNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSRDMNSRDVNRIMDVKVLRSAQFPEDSGSM
HCCCCCEEEEHHHHHHHHHCCCCEECCCHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
AHPVRPESYQEINNFYTATVYNKGAEVIRMQHTLLGKERFRRGMDLYFKRHDGHAVTIDD
CCCCCCHHHHHHHCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEHHH
FVAAMEDANGVDLTQFKLWYSQAGTPEVRVLSHFSEGRLEITMQQNCPPTPECHEKKPFH
HHHHHCCCCCCCHHHEEEEHHCCCCCHHHHEECCCCCEEEEEECCCCCCCCCCCCCCCCE
IPVRIALFDLKGEMIPIENELLELKEKEQRFIFSGLNEKPVVSLLREFSAPVKIYDDLDQ
EEEEEEEEECCCCEECCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEECCCCC
DDLLFLLRYETDGYAKWDAAQRLVLNCLNENLKLPASEWQVSKTLVAAFQHVLLDDSLDM
CCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
DLRAELLTPPGFEEVAATMKWVDVSKVESVRDYFRQQLGLGLYTEASDLYKELWEVEDHR
CCHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHH
MHGQAYGRRKLRNVCLWLMMKAKESDALELCREQFKDSRTMTDQIASCSLLVNCSRESHR
HCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHEEEEEECCCHHHH
NEAIEGFYKQWSHNELVLDKWFAMQAACELPGTLGHVKKLTQHPAFCIKNPNKVRALVGA
HHHHHHHHHHCCCCCEEHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEECCCHHHHHHHHH
FCMANPRNFHALDSSGYAFLSEVLIKLDTLNPQIAARLATPFTRWRSYDEPRQKLIQNQL
HHHCCCCCCEEECCCCHHHHHHHHHHHHCCCHHHHHHHHCHHHHHCCCCHHHHHHHHHHH
EQLTKLDLSRDLREVVDKSLIVEEK
HHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TMPDTTIYLKNYQPPSFTVETVELNFDLYDDHALVNSTLKLTRQKDGALHLYGEELELI
CCCCCEEEEECCCCCCEEEEEEEEEEEEECCHHHHHHHHHHEECCCCEEEEECCCEEEE
ALHLNGRPLEHEKYVLTKDALTIEQCPDEIVLNIVTRIKPQENTQLSGLYRSNHLFCTQC
EEEECCCCCCCCCEEEEECCEEHHHCCHHHHHHHHHHCCCCCCCEEEEEEECCCEEEEEC
EAEGFRRITYYLDRPDVLATFTTRITADKKQYPILLSNGNLMDTGETADGRHWVIWEDPF
CCCCCEEEEEEECCCCEEEEEEEEEECCCCCCCEEEECCCEEECCCCCCCCEEEEECCCC
KKPSYLFALVAGNLACVRDSFVTCSGRIVDLRIYVEPGNEDKCSHAMESLKKAMKWDEEV
CCCCEEEEEHHCCEEEEECCCEEECCEEEEEEEEEECCCCCHHHHHHHHHHHHHCCCHHH
YGREYDLDIYMIVAVSDFNMGAMENKGLNIFNSKYILARPETATDQDFADVEGVVGHEYF
CCCEECCEEEEEEEEECCCCCCCCCCCCEEECCEEEEECCCCCCCCCHHHHHHHHHHHHH
HNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSRDMNSRDVNRIMDVKVLRSAQFPEDSGSM
HCCCCCEEEEHHHHHHHHHCCCCEECCCHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
AHPVRPESYQEINNFYTATVYNKGAEVIRMQHTLLGKERFRRGMDLYFKRHDGHAVTIDD
CCCCCCHHHHHHHCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEHHH
FVAAMEDANGVDLTQFKLWYSQAGTPEVRVLSHFSEGRLEITMQQNCPPTPECHEKKPFH
HHHHHCCCCCCCHHHEEEEHHCCCCCHHHHEECCCCCEEEEEECCCCCCCCCCCCCCCCE
IPVRIALFDLKGEMIPIENELLELKEKEQRFIFSGLNEKPVVSLLREFSAPVKIYDDLDQ
EEEEEEEEECCCCEECCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEECCCCC
DDLLFLLRYETDGYAKWDAAQRLVLNCLNENLKLPASEWQVSKTLVAAFQHVLLDDSLDM
CCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
DLRAELLTPPGFEEVAATMKWVDVSKVESVRDYFRQQLGLGLYTEASDLYKELWEVEDHR
CCHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHH
MHGQAYGRRKLRNVCLWLMMKAKESDALELCREQFKDSRTMTDQIASCSLLVNCSRESHR
HCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHEEEEEECCCHHHH
NEAIEGFYKQWSHNELVLDKWFAMQAACELPGTLGHVKKLTQHPAFCIKNPNKVRALVGA
HHHHHHHHHHCCCCCEEHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEECCCHHHHHHHHH
FCMANPRNFHALDSSGYAFLSEVLIKLDTLNPQIAARLATPFTRWRSYDEPRQKLIQNQL
HHHCCCCCCEEECCCCHHHHHHHHHHHHCCCHHHHHHHHCHHHHHCCCCHHHHHHHHHHH
EQLTKLDLSRDLREVVDKSLIVEEK
HHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2436977; 3549459; 8905232; 9278503; 3018440; 2869947 [H]