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The map label for this gene is aroE [H]

Identifier: 54295636

GI number: 54295636

Start: 3109574

End: 3110371

Strand: Reverse

Name: aroE [H]

Synonym: lpl2723

Alternate gene names: 54295636

Gene position: 3110371-3109574 (Counterclockwise)

Preceding gene: 54295637

Following gene: 54295634

Centisome position: 92.97

GC content: 37.72

Gene sequence:

>798_bases
GTGCTTCGTCGTTTTGCAGTGATAGGTAATCCAATTGTACATAGTTTGTCTCCTGTCATTCATCAAATGTTTGCCCAACA
AACCCAAATTGAATTGATTTATGAAAAAATCCTGGGTGATGATGTCAAGTTTGAACAACAAATCTCTGATTTTTTTATCC
AGTATGGCAACGGGCTTAATGTCACTTTACCTTATAAAAAACGCGCTTATGAATTAGCAAAAGTACGCACACAAAGATGT
ACCCTGGCTGGAGCAGCAAACACCCTATGGATGGAGGAAAATCAATTACATGCTGATAATACCGATGGTATTGGGTTGAT
ACGTGATTTATCCCGATTTCTTGAGTTAAAGGATAAAAAAATTCTGATTTTGGGGGCTGGCGGAGCTGCAAGAGGGATTA
TTTTTCCTTTATTGGAAGCGAAACCGTTACAATTGATTGTTGCTAATCGGACTTTGGAAAAAGCCAAAGAATTACAGCGT
CAATTTCCTCAAATCAATGTCACAAGTTTTGCTGAATTAACAGAGTTCTTTGATTTAATCATCAATGCCACTTCTGCGAG
TTTGTCACATCAGGTCATTGTATTACCTGAAGAGGTGTTATCCCATAAACCATTTTGTTATGATTTGGCTTATAATCAAA
AAACAAGCACCGCCTTTGTTCAATATGCTCGTAATAGAGGGTGCGAAGCAGTTGATGGATTAGGTATGTTAGTAGAGCAA
GCTGCGGAAGCATTCTTTATATGGAATAATATCATGCCTTCTACCAAGGAAATCTTAGAGCAATTGCGATCCTTTTAA

Upstream 100 bases:

>100_bases
CTGGGCGCGATTTAAGAACAATTTGGATTGATGTGCTTGTTGCGTGAGAACAGTTTATAATTAGGAAAACCAATGAAACT
TATAGGATAAAGGAGTTTTT

Downstream 100 bases:

>100_bases
ATTGGACGCTTGCATAACGGTTTGATGTGCTTTGGCAACCAAACTCCGGTTAACTAAAAAAAGCGCTGACTTCTGCGGAT
GCAGCAATGGTGTCCTGATA

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MLRRFAVIGNPIVHSLSPVIHQMFAQQTQIELIYEKILGDDVKFEQQISDFFIQYGNGLNVTLPYKKRAYELAKVRTQRC
TLAGAANTLWMEENQLHADNTDGIGLIRDLSRFLELKDKKILILGAGGAARGIIFPLLEAKPLQLIVANRTLEKAKELQR
QFPQINVTSFAELTEFFDLIINATSASLSHQVIVLPEEVLSHKPFCYDLAYNQKTSTAFVQYARNRGCEAVDGLGMLVEQ
AAEAFFIWNNIMPSTKEILEQLRSF

Sequences:

>Translated_265_residues
MLRRFAVIGNPIVHSLSPVIHQMFAQQTQIELIYEKILGDDVKFEQQISDFFIQYGNGLNVTLPYKKRAYELAKVRTQRC
TLAGAANTLWMEENQLHADNTDGIGLIRDLSRFLELKDKKILILGAGGAARGIIFPLLEAKPLQLIVANRTLEKAKELQR
QFPQINVTSFAELTEFFDLIINATSASLSHQVIVLPEEVLSHKPFCYDLAYNQKTSTAFVQYARNRGCEAVDGLGMLVEQ
AAEAFFIWNNIMPSTKEILEQLRSF
>Mature_265_residues
MLRRFAVIGNPIVHSLSPVIHQMFAQQTQIELIYEKILGDDVKFEQQISDFFIQYGNGLNVTLPYKKRAYELAKVRTQRC
TLAGAANTLWMEENQLHADNTDGIGLIRDLSRFLELKDKKILILGAGGAARGIIFPLLEAKPLQLIVANRTLEKAKELQR
QFPQINVTSFAELTEFFDLIINATSASLSHQVIVLPEEVLSHKPFCYDLAYNQKTSTAFVQYARNRGCEAVDGLGMLVEQ
AAEAFFIWNNIMPSTKEILEQLRSF

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789675, Length=269, Percent_Identity=42.3791821561338, Blast_Score=209, Evalue=2e-55,
Organism=Escherichia coli, GI1787983, Length=258, Percent_Identity=29.0697674418605, Blast_Score=87, Evalue=9e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 29994; Mature: 29994

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRRFAVIGNPIVHSLSPVIHQMFAQQTQIELIYEKILGDDVKFEQQISDFFIQYGNGLN
CCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCE
VTLPYKKRAYELAKVRTQRCTLAGAANTLWMEENQLHADNTDGIGLIRDLSRFLELKDKK
EEECCHHHHHHHHHHHHHHHHEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCE
ILILGAGGAARGIIFPLLEAKPLQLIVANRTLEKAKELQRQFPQINVTSFAELTEFFDLI
EEEEECCCCCCHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
INATSASLSHQVIVLPEEVLSHKPFCYDLAYNQKTSTAFVQYARNRGCEAVDGLGMLVEQ
HHHCCCCCCCEEEEECHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHH
AAEAFFIWNNIMPSTKEILEQLRSF
HHHHEEHHHCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MLRRFAVIGNPIVHSLSPVIHQMFAQQTQIELIYEKILGDDVKFEQQISDFFIQYGNGLN
CCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCE
VTLPYKKRAYELAKVRTQRCTLAGAANTLWMEENQLHADNTDGIGLIRDLSRFLELKDKK
EEECCHHHHHHHHHHHHHHHHEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCE
ILILGAGGAARGIIFPLLEAKPLQLIVANRTLEKAKELQRQFPQINVTSFAELTEFFDLI
EEEEECCCCCCHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
INATSASLSHQVIVLPEEVLSHKPFCYDLAYNQKTSTAFVQYARNRGCEAVDGLGMLVEQ
HHHCCCCCCCEEEEECHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHH
AAEAFFIWNNIMPSTKEILEQLRSF
HHHHEEHHHCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA