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The map label for this gene is yvmA [H]

Identifier: 54295339

GI number: 54295339

Start: 2754598

End: 2755830

Strand: Direct

Name: yvmA [H]

Synonym: lpl2424

Alternate gene names: 54295339

Gene position: 2754598-2755830 (Clockwise)

Preceding gene: 54295338

Following gene: 54295341

Centisome position: 82.33

GC content: 40.23

Gene sequence:

>1233_bases
ATGATTTTTTATATGCCTAAATCACATAATTCCATTATATTCCTTGGTTTGCTTTCTGCGTTTTCTTTGCTTACATTTGA
TCTTTATCAACCATCACTGCCTTTCATAACGAATTATTTTAATATTACCCCAAGTATGGGGCAATTAACCCTAAGTATTT
ATTTGCTAGTTTATGGCATCACTCATCTTCTATGGGGACCACTTATAGACCATTTTGGGCGCCGGCGCCTACTTCCGGGA
ACCCTTTTATTAGCCTTAATTGGCAGTTTAATGTGTGCTTTTGCACCGAATATCACCATGCTTATTTGCGGTCGTGCCCT
ACAAGGATTCGCCTTATGTTGCGCAAATCTCATTGCCTATTCCGCAGCACGTGATTTTGAAGACACGATTGTTCGCGCCA
AAGTGCTGTCCTATATTTCCATGACCGTTTCAGTTTCACCGATTATAGCCCCGGTAATTGGTGCACTTATCTTTCATCAT
TTTGGCTGGCAAGCCAATTTTATAGTCATGGCAATCGTTGCCTGTATTCTATTGATACAAACCAAGCTCTCCTTGTTAGA
GTCCCCTTTCTGGACGCCCCCCCAGGAGAGGTTCTCGGTAAAAAAAATACTCCAGGAATATAAGTCCATAATCAATATAC
CCTCTCTATGGTGCGCATCATTTATTTTAATGTTTGGCATTTCTGCTGTCATGCTCACTGTAATTAATTCCTCTTACCTT
ATTATCGAGGTACTGAATTACTCTCCACTTGCCTATGGACTTATTTTTATTCTGAATGGTTTAAATATTATTTTTGGAAA
CTATCTGGGCATTTGGCTTCGTGACCGATTACCCATTATAACTACCATCTATTTGGGGAACTGGTTCATTGTCCTTGGTG
GTACAGCGATGTTGGTTACCTCCAAATTGTTTGGATTTAGTCTGTTAGCATTGTCATTTTCATTAATTGCCAACTTGGGA
ATTAGTGTCAGTGCCGCTCCAACTATCTCCATCGCCCTAACGGATTTTAAGCAAAATGCAGGAATAGTTATGGCTTTTAT
GAATACCATACGTTTAATCGGCCCCTCTCTTTTAACTATTCTAACCGGCTATTTGTTGACAAGGAATCTTGACGCACTTC
CACTGGGATTAATAGGCTCAGGAATTGGAGCCCTCTTTTTCTCATGGCATTTTAGCCGATTAACTACTGAATCGAGAAAC
TCGGACATGGATAGCAAAGAAGCGTTGACCTAA

Upstream 100 bases:

>100_bases
ATCTGTCCCAGAGTAAAGCAAGTTGGCAGTTGCCAACTTGCTTTAATATTTTCTTTCAAATGCAAGCCGAATTTGGTTAC
AATCGCATAATTTTTGGTGA

Downstream 100 bases:

>100_bases
CAGTCTGTTAACTTCCCCATATTGGATATAAAATTTTTTACATAATTCTCCTGAAACACAGAGCCGCACATTGGTTCTGT
GAAGGTAAAGCAAAACATGA

Product: hypothetical protein

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MIFYMPKSHNSIIFLGLLSAFSLLTFDLYQPSLPFITNYFNITPSMGQLTLSIYLLVYGITHLLWGPLIDHFGRRRLLPG
TLLLALIGSLMCAFAPNITMLICGRALQGFALCCANLIAYSAARDFEDTIVRAKVLSYISMTVSVSPIIAPVIGALIFHH
FGWQANFIVMAIVACILLIQTKLSLLESPFWTPPQERFSVKKILQEYKSIINIPSLWCASFILMFGISAVMLTVINSSYL
IIEVLNYSPLAYGLIFILNGLNIIFGNYLGIWLRDRLPIITTIYLGNWFIVLGGTAMLVTSKLFGFSLLALSFSLIANLG
ISVSAAPTISIALTDFKQNAGIVMAFMNTIRLIGPSLLTILTGYLLTRNLDALPLGLIGSGIGALFFSWHFSRLTTESRN
SDMDSKEALT

Sequences:

>Translated_410_residues
MIFYMPKSHNSIIFLGLLSAFSLLTFDLYQPSLPFITNYFNITPSMGQLTLSIYLLVYGITHLLWGPLIDHFGRRRLLPG
TLLLALIGSLMCAFAPNITMLICGRALQGFALCCANLIAYSAARDFEDTIVRAKVLSYISMTVSVSPIIAPVIGALIFHH
FGWQANFIVMAIVACILLIQTKLSLLESPFWTPPQERFSVKKILQEYKSIINIPSLWCASFILMFGISAVMLTVINSSYL
IIEVLNYSPLAYGLIFILNGLNIIFGNYLGIWLRDRLPIITTIYLGNWFIVLGGTAMLVTSKLFGFSLLALSFSLIANLG
ISVSAAPTISIALTDFKQNAGIVMAFMNTIRLIGPSLLTILTGYLLTRNLDALPLGLIGSGIGALFFSWHFSRLTTESRN
SDMDSKEALT
>Mature_410_residues
MIFYMPKSHNSIIFLGLLSAFSLLTFDLYQPSLPFITNYFNITPSMGQLTLSIYLLVYGITHLLWGPLIDHFGRRRLLPG
TLLLALIGSLMCAFAPNITMLICGRALQGFALCCANLIAYSAARDFEDTIVRAKVLSYISMTVSVSPIIAPVIGALIFHH
FGWQANFIVMAIVACILLIQTKLSLLESPFWTPPQERFSVKKILQEYKSIINIPSLWCASFILMFGISAVMLTVINSSYL
IIEVLNYSPLAYGLIFILNGLNIIFGNYLGIWLRDRLPIITTIYLGNWFIVLGGTAMLVTSKLFGFSLLALSFSLIANLG
ISVSAAPTISIALTDFKQNAGIVMAFMNTIRLIGPSLLTILTGYLLTRNLDALPLGLIGSGIGALFFSWHFSRLTTESRN
SDMDSKEALT

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. TCR/tet family [H]

Homologues:

Organism=Escherichia coli, GI1790146, Length=341, Percent_Identity=28.4457478005865, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788509, Length=356, Percent_Identity=25.2808988764045, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI48994889, Length=360, Percent_Identity=23.6111111111111, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787065, Length=331, Percent_Identity=23.2628398791541, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI87082312, Length=250, Percent_Identity=24.8, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1790794, Length=190, Percent_Identity=28.4210526315789, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87081738, Length=164, Percent_Identity=30.4878048780488, Blast_Score=64, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319657, Length=160, Percent_Identity=28.75, Blast_Score=64, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 45244; Mature: 45244

Theoretical pI: Translated: 8.92; Mature: 8.92

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFYMPKSHNSIIFLGLLSAFSLLTFDLYQPSLPFITNYFNITPSMGQLTLSIYLLVYGI
CEEEEECCCCCEEHHHHHHHHHHHHHHHCCCCCCHHHHHEECCCCHHHHHHHHHHHHHHH
THLLWGPLIDHFGRRRLLPGTLLLALIGSLMCAFAPNITMLICGRALQGFALCCANLIAY
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHEEHHHHHHHHHHHHHHHHHHH
SAARDFEDTIVRAKVLSYISMTVSVSPIIAPVIGALIFHHFGWQANFIVMAIVACILLIQ
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
TKLSLLESPFWTPPQERFSVKKILQEYKSIINIPSLWCASFILMFGISAVMLTVINSSYL
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEE
IIEVLNYSPLAYGLIFILNGLNIIFGNYLGIWLRDRLPIITTIYLGNWFIVLGGTAMLVT
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCEEEEECCHHHHHH
SKLFGFSLLALSFSLIANLGISVSAAPTISIALTDFKQNAGIVMAFMNTIRLIGPSLLTI
HHHHHHHHHHHHHHHHHHCCCCEECCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
LTGYLLTRNLDALPLGLIGSGIGALFFSWHFSRLTTESRNSDMDSKEALT
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCC
>Mature Secondary Structure
MIFYMPKSHNSIIFLGLLSAFSLLTFDLYQPSLPFITNYFNITPSMGQLTLSIYLLVYGI
CEEEEECCCCCEEHHHHHHHHHHHHHHHCCCCCCHHHHHEECCCCHHHHHHHHHHHHHHH
THLLWGPLIDHFGRRRLLPGTLLLALIGSLMCAFAPNITMLICGRALQGFALCCANLIAY
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHEEHHHHHHHHHHHHHHHHHHH
SAARDFEDTIVRAKVLSYISMTVSVSPIIAPVIGALIFHHFGWQANFIVMAIVACILLIQ
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
TKLSLLESPFWTPPQERFSVKKILQEYKSIINIPSLWCASFILMFGISAVMLTVINSSYL
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEE
IIEVLNYSPLAYGLIFILNGLNIIFGNYLGIWLRDRLPIITTIYLGNWFIVLGGTAMLVT
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCEEEEECCHHHHHH
SKLFGFSLLALSFSLIANLGISVSAAPTISIALTDFKQNAGIVMAFMNTIRLIGPSLLTI
HHHHHHHHHHHHHHHHHHCCCCEECCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
LTGYLLTRNLDALPLGLIGSGIGALFFSWHFSRLTTESRNSDMDSKEALT
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]