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The map label for this gene is yggV [C]

Identifier: 54295319

GI number: 54295319

Start: 2733713

End: 2734297

Strand: Direct

Name: yggV [C]

Synonym: lpl2404

Alternate gene names: 54295319

Gene position: 2733713-2734297 (Clockwise)

Preceding gene: 54295317

Following gene: 54295320

Centisome position: 81.71

GC content: 41.88

Gene sequence:

>585_bases
ATGAAAGAAATTATTTTGGCAACCAGTAACCCTGGAAAAATAAAAGAATTAGAACAATTACTAGCCCCCACCCTATGCAT
TCCCCAAGCCGACTTGGGTATATCCGATGCGGAAGAAACAGGATTAAGTTTTATAGAGAATGCCATTCTCAAAGCCCGTC
ATGCCAGCTCATTAGCCAATAAACCAGCTTTAGCCGACGACTCGGGACTTGTAGTCCCCTCTTTAAATGGAGAGCCGGGT
ATCTATTCAGCACGCTATGCTGGAATAAAGGCGAATGACGAAAACAATATTCAACAATTGTTAAGTAAAATGGCTGATTT
ATCCCAAGAACAAAGACAAGCCTATTTTTTTTGCGCAATAGCGCTAATGCAACATGCCAAAGACCCAACACCGCTCATTG
CCACAGGCGTATTTCATGGCGTTATTAGCGTGAAACCTTCAGGAACAAATGGCTTTGGGTATGACCCGGTATTTTATCTC
AACGAATATCAATGCACAGCCGCTGAATTACCTGCTAAAATTAAAAATAGGATTAGCCATCGCGCAAAAGCTTTAAACCA
ATTACGCGCCCTTCTTCCAGATTAA

Upstream 100 bases:

>100_bases
ATGGTTTTAAATACCAGGGAGTCTTCTTGATATTTTTTTCCAAAATTCTCATGCATAATTATCCTTTTTATGAATACTGA
ATTAATAGCATGGAATAAGA

Downstream 100 bases:

>100_bases
TATGAACAGTGAAGTAGATACTCTTTTTGCACAAGCCTATAAGCTTCAATATGAAGGCCATTTACCTCAAGCCATTAGCT
TATATGAGCAGATACTTGCC

Product: putative deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MKEIILATSNPGKIKELEQLLAPTLCIPQADLGISDAEETGLSFIENAILKARHASSLANKPALADDSGLVVPSLNGEPG
IYSARYAGIKANDENNIQQLLSKMADLSQEQRQAYFFCAIALMQHAKDPTPLIATGVFHGVISVKPSGTNGFGYDPVFYL
NEYQCTAAELPAKIKNRISHRAKALNQLRALLPD

Sequences:

>Translated_194_residues
MKEIILATSNPGKIKELEQLLAPTLCIPQADLGISDAEETGLSFIENAILKARHASSLANKPALADDSGLVVPSLNGEPG
IYSARYAGIKANDENNIQQLLSKMADLSQEQRQAYFFCAIALMQHAKDPTPLIATGVFHGVISVKPSGTNGFGYDPVFYL
NEYQCTAAELPAKIKNRISHRAKALNQLRALLPD
>Mature_194_residues
MKEIILATSNPGKIKELEQLLAPTLCIPQADLGISDAEETGLSFIENAILKARHASSLANKPALADDSGLVVPSLNGEPG
IYSARYAGIKANDENNIQQLLSKMADLSQEQRQAYFFCAIALMQHAKDPTPLIATGVFHGVISVKPSGTNGFGYDPVFYL
NEYQCTAAELPAKIKNRISHRAKALNQLRALLPD

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Homo sapiens, GI15626999, Length=195, Percent_Identity=31.7948717948718, Blast_Score=75, Evalue=3e-14,
Organism=Escherichia coli, GI1789324, Length=190, Percent_Identity=53.1578947368421, Blast_Score=209, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI17556833, Length=189, Percent_Identity=29.1005291005291, Blast_Score=67, Evalue=7e-12,
Organism=Drosophila melanogaster, GI19920712, Length=188, Percent_Identity=34.0425531914894, Blast_Score=86, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 20961; Mature: 20961

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEIILATSNPGKIKELEQLLAPTLCIPQADLGISDAEETGLSFIENAILKARHASSLAN
CCCEEEEECCCCHHHHHHHHHCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
KPALADDSGLVVPSLNGEPGIYSARYAGIKANDENNIQQLLSKMADLSQEQRQAYFFCAI
CCCCCCCCCEEEECCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALMQHAKDPTPLIATGVFHGVISVKPSGTNGFGYDPVFYLNEYQCTAAELPAKIKNRISH
HHHHHCCCCCCCHHHHHHHHEEEECCCCCCCCCCCCEEEECCCCCCHHHCCHHHHHHHHH
RAKALNQLRALLPD
HHHHHHHHHHHCCC
>Mature Secondary Structure
MKEIILATSNPGKIKELEQLLAPTLCIPQADLGISDAEETGLSFIENAILKARHASSLAN
CCCEEEEECCCCHHHHHHHHHCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
KPALADDSGLVVPSLNGEPGIYSARYAGIKANDENNIQQLLSKMADLSQEQRQAYFFCAI
CCCCCCCCCEEEECCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALMQHAKDPTPLIATGVFHGVISVKPSGTNGFGYDPVFYLNEYQCTAAELPAKIKNRISH
HHHHHCCCCCCCHHHHHHHHEEEECCCCCCCCCCCCEEEECCCCCCHHHCCHHHHHHHHH
RAKALNQLRALLPD
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA