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The map label for this gene is iucD [H]

Identifier: 54294867

GI number: 54294867

Start: 2184855

End: 2186192

Strand: Direct

Name: iucD [H]

Synonym: lpl1946

Alternate gene names: 54294867

Gene position: 2184855-2186192 (Clockwise)

Preceding gene: 54294866

Following gene: 54294868

Centisome position: 65.3

GC content: 36.17

Gene sequence:

>1338_bases
ATGATGATGAAATCATTGCGTAATACTGAGGTTGTTGATGTAATCGGAGTTGGCATTGGACCCTCCAATTTAAGTCTCGC
TGCTTTACTATCACCGATAAAAAACATTTCCAGTTGTTTTTATGATCGCAATGATTCCTTTTCATGGCACCCTGGTATGC
TTCTTCCAGACAGTGAGATTCAAGTCAATTATTTAAATGATTTGGTAACACTGGTTGATCCTACTAACCCCTTTTCTTTT
ATTGCTTACCTTGCAAAACATAAACGCCTATATCGATTTATCAATGCACAATTTAAATACGTTTTACGTTCTGAATTTAG
CCAATATTTAAATTGGGTCAGTCGATCTTTATCCAACTTATTTTTTAATGAGGAAGTGATTGACGTTTGTTTTGATCATT
CGCATTTTTCAATGCAAACCACAAAAAGAATAATAAAAGGAAAACACCTCGTTTTAGGTAATGGTTTAACAGCCAGGATA
CCCTCATGCGCCAAATCCTGTCTGGGAAAAACAGTATTTCATAATTCAGAGTATTTGCATAAATCGCCTAATTGGTATGG
GAAAAGTATTGCGATAATCGGTGGAGGTCAAAGTGGCGCTGAAATTGTACACTCCATTTTATCCCATAGTGATGGATTAC
CCGAAAAATTAACCTGGATCTCAAGAAGGAATCAGCTGCTACCAATGGACACATCTCCTTTTGTTAATGAGTTTTTTACT
CCGAATTACGCCAATCACTTTTACCAATTTTCCAGTGAAATAAAATCACGCTTATTACAAGAGCAGCTGTTAGCGAGTGA
TGGTATTTCTGAAGATCTCTTAAGAACTATCTATCAAAAGTTATATCGAATTGAGTTTTTAGAAAATAAAGGCCAGTTTT
TTCAATTTTTAGCAAAGTCTCAAATCATTAATATAGAGAGAGCCTTTGGAACTCATCAGTTTATCTTGGTCGTAGAGGAT
CTTGAATCTGAGAACAAGCAAATAATCCCTGCAGACATCATTATTTTATGCACCGGTTATGAATGGACTTTTCCTCCATA
TCTTAGCTCACTATCCAACCAAATACCCTTACATAATAACAGGTTTTATATCAATCATGATTTTTCCATCCACTGGGATG
GCCCAAACCAAAATCGCATTTACGTACAAAATGGAGCCCGTCATTCTCATGGCATTGCAGATCCCAATTTAAACATTATG
GCTTGGCGCAGTGCGACAATTATCAATAGCATTATTCAAAAACCTATCTATGATCTCAGTAGTGAAAGTAGCGCCTTAAG
TTGGGAACCCGAGATTATATCTCAAAATCAGGAATGTAAATATGCTTCAATCGCCTAA

Upstream 100 bases:

>100_bases
ATAAAAGATTTTTTTGCTCTCCCCCTGCATTCTATACAAAAAAATGTGCCAATAAATCGAAATCGAATTTCTCAAGAATT
AATGTTTATCAAGGAGGAGC

Downstream 100 bases:

>100_bases
CCTAATCAGTCACCCTAAACCACAATTAAATTTTTCAACTGGAGAAGAAATTGCTCCTGGCGTAGTAGTCAACCCTATTG
ATTTTAGTTTTAATCAGATA

Product: hypothetical protein

Products: NA

Alternate protein names: Lysine 6-N-hydroxylase; Lysine N(6)-hydroxylase; Lysine-N-oxygenase [H]

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MMMKSLRNTEVVDVIGVGIGPSNLSLAALLSPIKNISSCFYDRNDSFSWHPGMLLPDSEIQVNYLNDLVTLVDPTNPFSF
IAYLAKHKRLYRFINAQFKYVLRSEFSQYLNWVSRSLSNLFFNEEVIDVCFDHSHFSMQTTKRIIKGKHLVLGNGLTARI
PSCAKSCLGKTVFHNSEYLHKSPNWYGKSIAIIGGGQSGAEIVHSILSHSDGLPEKLTWISRRNQLLPMDTSPFVNEFFT
PNYANHFYQFSSEIKSRLLQEQLLASDGISEDLLRTIYQKLYRIEFLENKGQFFQFLAKSQIINIERAFGTHQFILVVED
LESENKQIIPADIIILCTGYEWTFPPYLSSLSNQIPLHNNRFYINHDFSIHWDGPNQNRIYVQNGARHSHGIADPNLNIM
AWRSATIINSIIQKPIYDLSSESSALSWEPEIISQNQECKYASIA

Sequences:

>Translated_445_residues
MMMKSLRNTEVVDVIGVGIGPSNLSLAALLSPIKNISSCFYDRNDSFSWHPGMLLPDSEIQVNYLNDLVTLVDPTNPFSF
IAYLAKHKRLYRFINAQFKYVLRSEFSQYLNWVSRSLSNLFFNEEVIDVCFDHSHFSMQTTKRIIKGKHLVLGNGLTARI
PSCAKSCLGKTVFHNSEYLHKSPNWYGKSIAIIGGGQSGAEIVHSILSHSDGLPEKLTWISRRNQLLPMDTSPFVNEFFT
PNYANHFYQFSSEIKSRLLQEQLLASDGISEDLLRTIYQKLYRIEFLENKGQFFQFLAKSQIINIERAFGTHQFILVVED
LESENKQIIPADIIILCTGYEWTFPPYLSSLSNQIPLHNNRFYINHDFSIHWDGPNQNRIYVQNGARHSHGIADPNLNIM
AWRSATIINSIIQKPIYDLSSESSALSWEPEIISQNQECKYASIA
>Mature_445_residues
MMMKSLRNTEVVDVIGVGIGPSNLSLAALLSPIKNISSCFYDRNDSFSWHPGMLLPDSEIQVNYLNDLVTLVDPTNPFSF
IAYLAKHKRLYRFINAQFKYVLRSEFSQYLNWVSRSLSNLFFNEEVIDVCFDHSHFSMQTTKRIIKGKHLVLGNGLTARI
PSCAKSCLGKTVFHNSEYLHKSPNWYGKSIAIIGGGQSGAEIVHSILSHSDGLPEKLTWISRRNQLLPMDTSPFVNEFFT
PNYANHFYQFSSEIKSRLLQEQLLASDGISEDLLRTIYQKLYRIEFLENKGQFFQFLAKSQIINIERAFGTHQFILVVED
LESENKQIIPADIIILCTGYEWTFPPYLSSLSNQIPLHNNRFYINHDFSIHWDGPNQNRIYVQNGARHSHGIADPNLNIM
AWRSATIINSIIQKPIYDLSSESSALSWEPEIISQNQECKYASIA

Specific function: This is one of the proteins involved in the biosynthesis of siderophores (such as the dihydroxamate siderophore, aerobactin), which are chelators that mediate the high-affinity iron transport systems induced by the organism under iron-stressed conditions

COG id: COG3486

COG function: function code Q; Lysine/ornithine N-monooxygenase

Gene ontology:

Cell location: Cytoplasm. Cell membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027 [H]

Pfam domain/function: PF07992 Pyr_redox_2 [H]

EC number: =1.14.13.59 [H]

Molecular weight: Translated: 50921; Mature: 50921

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMMKSLRNTEVVDVIGVGIGPSNLSLAALLSPIKNISSCFYDRNDSFSWHPGMLLPDSEI
CCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCE
QVNYLNDLVTLVDPTNPFSFIAYLAKHKRLYRFINAQFKYVLRSEFSQYLNWVSRSLSNL
EEEEHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFNEEVIDVCFDHSHFSMQTTKRIIKGKHLVLGNGLTARIPSCAKSCLGKTVFHNSEYLH
HCCHHHHHHHHCCCCCHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCHHHC
KSPNWYGKSIAIIGGGQSGAEIVHSILSHSDGLPEKLTWISRRNQLLPMDTSPFVNEFFT
CCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHCC
PNYANHFYQFSSEIKSRLLQEQLLASDGISEDLLRTIYQKLYRIEFLENKGQFFQFLAKS
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
QIINIERAFGTHQFILVVEDLESENKQIIPADIIILCTGYEWTFPPYLSSLSNQIPLHNN
HHEEHHHHCCCEEEEEEEECCCCCCCEECCEEEEEEEECCCCCCCHHHHHHCCCCCCCCC
RFYINHDFSIHWDGPNQNRIYVQNGARHSHGIADPNLNIMAWRSATIINSIIQKPIYDLS
EEEEEECEEEEECCCCCCEEEEECCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHCCC
SESSALSWEPEIISQNQECKYASIA
CCCCCCCCCHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MMMKSLRNTEVVDVIGVGIGPSNLSLAALLSPIKNISSCFYDRNDSFSWHPGMLLPDSEI
CCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCE
QVNYLNDLVTLVDPTNPFSFIAYLAKHKRLYRFINAQFKYVLRSEFSQYLNWVSRSLSNL
EEEEHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFNEEVIDVCFDHSHFSMQTTKRIIKGKHLVLGNGLTARIPSCAKSCLGKTVFHNSEYLH
HCCHHHHHHHHCCCCCHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCHHHC
KSPNWYGKSIAIIGGGQSGAEIVHSILSHSDGLPEKLTWISRRNQLLPMDTSPFVNEFFT
CCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHCC
PNYANHFYQFSSEIKSRLLQEQLLASDGISEDLLRTIYQKLYRIEFLENKGQFFQFLAKS
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
QIINIERAFGTHQFILVVEDLESENKQIIPADIIILCTGYEWTFPPYLSSLSNQIPLHNN
HHEEHHHHCCCEEEEEEEECCCCCCCEECCEEEEEEEECCCCCCCHHHHHHCCCCCCCCC
RFYINHDFSIHWDGPNQNRIYVQNGARHSHGIADPNLNIMAWRSATIINSIIQKPIYDLS
EEEEEECEEEEECCCCCCEEEEECCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHCCC
SESSALSWEPEIISQNQECKYASIA
CCCCCCCCCHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3275632; 10064136 [H]