Click here to switch to the map view.

The map label for this gene is paaF [H]

Identifier: 54294715

GI number: 54294715

Start: 2005237

End: 2006067

Strand: Direct

Name: paaF [H]

Synonym: lpl1792

Alternate gene names: 54294715

Gene position: 2005237-2006067 (Clockwise)

Preceding gene: 54294714

Following gene: 54294716

Centisome position: 59.93

GC content: 38.87

Gene sequence:

>831_bases
GTGTATTTCGCATGTAAAAGGAAAGGAACAATAGGCATGAGTGATTTATTATATGAAATTCAAGATAAAGTAGGTTTACT
TACTATGAATCGAATTAGCAAGCATAATGCGTTCGATAATCAACTGCTGACTGAAATGAAAATAAGACTTGACTCCGCAA
TAAATGATACTAACGTTCGCGTCATAGTACTTAAAGCGAATGGAAAGCATTTTTCAGCTGGTGCTGATTTGACCTGGATG
CAAAGCATGTCTAACTTTACTGAAGAAGAAAACCTGGAAGACAGCATGGTATTAGGTAATTTAATGTATAGTCTCAGTCA
AAGCCCAAAACCTACTATCGCCATGGTTCAAGGTGCCGCTTTTGGTGGTGGAGCTGGATTGGCAGCAGCATGTGATATAG
CCATTGCATCTACTTCAGCACGTTTTTGTTTTTCTGAAGTGAAATTAGGCCTTATTCCAGCAGTAATTAGTCCCTATGTA
GTTAGAGCAATAGGGGAGCGAGCAGCGAAAATGTTATTCATGAGTGCTGAAGTTTTTGATGCCACACGCGCATATTCTCT
TAATTTAGTTCAGCACTGCGTCTCTGATGATACGTTGTTGGAGTTTACTCTCAAATACGCCTCGCAAATCAGTAATAATG
CTCCAGAAGCGGTTAAAAACTCAAAACAACTGGCACAATACGTCGCTAATAAAAAAATAGATGAAGAACTGGTTCACTAC
ACTGCTTCTCTGATTGCCCATAAAAGAGTATCTGATGAAGGGCAAGAAGGGCTTAAAGCATTTCTCAATAAAGAAATACC
CAACTGGAATAAAGGTTCTGGACATGTTTAA

Upstream 100 bases:

>100_bases
CTTTGGGATGATGGAGTCATCGCCCCTCAGGATACACGCAAAATACTCGGACTTGGATTATCTGCAGCCTTAAATGCACC
GATTGAGGATACTCGTTTCG

Downstream 100 bases:

>100_bases
TAAAATATTAATTGCTAACCGAGGCGAAATAGCCTGTCGAATCATTAAAACAGCAAATTCTATGGGTATTCAGGCTGTTG
CCGTTTATTCAGCAGCAGAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MYFACKRKGTIGMSDLLYEIQDKVGLLTMNRISKHNAFDNQLLTEMKIRLDSAINDTNVRVIVLKANGKHFSAGADLTWM
QSMSNFTEEENLEDSMVLGNLMYSLSQSPKPTIAMVQGAAFGGGAGLAAACDIAIASTSARFCFSEVKLGLIPAVISPYV
VRAIGERAAKMLFMSAEVFDATRAYSLNLVQHCVSDDTLLEFTLKYASQISNNAPEAVKNSKQLAQYVANKKIDEELVHY
TASLIAHKRVSDEGQEGLKAFLNKEIPNWNKGSGHV

Sequences:

>Translated_276_residues
MYFACKRKGTIGMSDLLYEIQDKVGLLTMNRISKHNAFDNQLLTEMKIRLDSAINDTNVRVIVLKANGKHFSAGADLTWM
QSMSNFTEEENLEDSMVLGNLMYSLSQSPKPTIAMVQGAAFGGGAGLAAACDIAIASTSARFCFSEVKLGLIPAVISPYV
VRAIGERAAKMLFMSAEVFDATRAYSLNLVQHCVSDDTLLEFTLKYASQISNNAPEAVKNSKQLAQYVANKKIDEELVHY
TASLIAHKRVSDEGQEGLKAFLNKEIPNWNKGSGHV
>Mature_276_residues
MYFACKRKGTIGMSDLLYEIQDKVGLLTMNRISKHNAFDNQLLTEMKIRLDSAINDTNVRVIVLKANGKHFSAGADLTWM
QSMSNFTEEENLEDSMVLGNLMYSLSQSPKPTIAMVQGAAFGGGAGLAAACDIAIASTSARFCFSEVKLGLIPAVISPYV
VRAIGERAAKMLFMSAEVFDATRAYSLNLVQHCVSDDTLLEFTLKYASQISNNAPEAVKNSKQLAQYVANKKIDEELVHY
TASLIAHKRVSDEGQEGLKAFLNKEIPNWNKGSGHV

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=253, Percent_Identity=30.8300395256917, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI31542718, Length=256, Percent_Identity=26.171875, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI213417737, Length=204, Percent_Identity=26.9607843137255, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI157694516, Length=204, Percent_Identity=26.9607843137255, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI68989263, Length=196, Percent_Identity=30.1020408163265, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI70995211, Length=236, Percent_Identity=29.2372881355932, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI4502327, Length=254, Percent_Identity=29.9212598425197, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI157694520, Length=173, Percent_Identity=27.1676300578035, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI260274832, Length=272, Percent_Identity=26.4705882352941, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI45643119, Length=272, Percent_Identity=26.4705882352941, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI260275230, Length=272, Percent_Identity=26.4705882352941, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI1787659, Length=264, Percent_Identity=33.3333333333333, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1788597, Length=263, Percent_Identity=27.7566539923954, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI87082183, Length=252, Percent_Identity=27.3809523809524, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI221142681, Length=258, Percent_Identity=27.1317829457364, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787660, Length=261, Percent_Identity=26.8199233716475, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790281, Length=192, Percent_Identity=26.5625, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17540714, Length=201, Percent_Identity=33.8308457711443, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17554946, Length=253, Percent_Identity=30.0395256916996, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI25145438, Length=254, Percent_Identity=29.5275590551181, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17536985, Length=225, Percent_Identity=26.6666666666667, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17540306, Length=234, Percent_Identity=26.9230769230769, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17535521, Length=251, Percent_Identity=25.8964143426295, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17534483, Length=267, Percent_Identity=24.7191011235955, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17549921, Length=225, Percent_Identity=26.6666666666667, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320241, Length=222, Percent_Identity=25.2252252252252, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24653139, Length=256, Percent_Identity=31.25, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI20129971, Length=245, Percent_Identity=29.7959183673469, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24653477, Length=245, Percent_Identity=29.7959183673469, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI19920382, Length=223, Percent_Identity=32.7354260089686, Blast_Score=91, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24654903, Length=186, Percent_Identity=29.0322580645161, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 30240; Mature: 30240

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYFACKRKGTIGMSDLLYEIQDKVGLLTMNRISKHNAFDNQLLTEMKIRLDSAINDTNVR
CCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEE
VIVLKANGKHFSAGADLTWMQSMSNFTEEENLEDSMVLGNLMYSLSQSPKPTIAMVQGAA
EEEEEECCCEECCCCCHHHHHHHHHCHHHCCCHHHHHHHHHHHHHCCCCCCCEEEEECCC
FGGGAGLAAACDIAIASTSARFCFSEVKLGLIPAVISPYVVRAIGERAAKMLFMSAEVFD
CCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATRAYSLNLVQHCVSDDTLLEFTLKYASQISNNAPEAVKNSKQLAQYVANKKIDEELVHY
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHH
TASLIAHKRVSDEGQEGLKAFLNKEIPNWNKGSGHV
HHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MYFACKRKGTIGMSDLLYEIQDKVGLLTMNRISKHNAFDNQLLTEMKIRLDSAINDTNVR
CCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEE
VIVLKANGKHFSAGADLTWMQSMSNFTEEENLEDSMVLGNLMYSLSQSPKPTIAMVQGAA
EEEEEECCCEECCCCCHHHHHHHHHCHHHCCCHHHHHHHHHHHHHCCCCCCCEEEEECCC
FGGGAGLAAACDIAIASTSARFCFSEVKLGLIPAVISPYVVRAIGERAAKMLFMSAEVFD
CCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATRAYSLNLVQHCVSDDTLLEFTLKYASQISNNAPEAVKNSKQLAQYVANKKIDEELVHY
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHH
TASLIAHKRVSDEGQEGLKAFLNKEIPNWNKGSGHV
HHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]