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The map label for this gene is tadA [H]

Identifier: 54294609

GI number: 54294609

Start: 1879890

End: 1880339

Strand: Reverse

Name: tadA [H]

Synonym: lpl1685

Alternate gene names: 54294609

Gene position: 1880339-1879890 (Counterclockwise)

Preceding gene: 54294610

Following gene: 54294606

Centisome position: 56.2

GC content: 41.11

Gene sequence:

>450_bases
ATGGGAATGATTGATAAATTTTGGATGCAACTGGCTTACGAGCAAGCGGTTATAGCTCGTAATGAAGGAGAGGTTCCTGT
TGGGGCTGTGTTGGTTAGCAAAGATAATCAATTATTAGGCGTTGGCAGAAATGTCATTGAAAAAAGTCATGATCCTTCTG
ATCATGCTGAAATTAGAGCAATACGACAAGCCTCGAGAAAGCTAAATAATCATAGATTATTGGATACAACGCTTTATGTT
ACTCTCGAACCCTGTGTGATGTGTGCGGGGCTTATGGTTCACGCACGCATCAAACGGCTGGTATTTGCTACCCGAGATTT
TAAAGCAGGGGCAGCTGGCTCAATATTTAATGTTTTACATGCTCTAAACCATTCGGTATTAATAGATGAAGGCATTATGC
AGGCTGAGTGTTCTCAATTGCTGTCAGATTTTTTCAGAAAGCTTCGCTAG

Upstream 100 bases:

>100_bases
GGGATTTTTTAGGAAAAGTATCCAATCGAATTATTAATGAAGTAGAGGGAGTATCACGTGTCACTTACGATATTTCTGGC
AAGCCACCTGCTACCATTGA

Downstream 100 bases:

>100_bases
TAATTTATCTTGGCATACTTCTTAATACTTGCTTTTAGAAATTTCCAAAATTAATTTTTCTTTTAAAATTGTTTTTTCCT
CATGATTCAGGGAATAACCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 149; Mature: 148

Protein sequence:

>149_residues
MGMIDKFWMQLAYEQAVIARNEGEVPVGAVLVSKDNQLLGVGRNVIEKSHDPSDHAEIRAIRQASRKLNNHRLLDTTLYV
TLEPCVMCAGLMVHARIKRLVFATRDFKAGAAGSIFNVLHALNHSVLIDEGIMQAECSQLLSDFFRKLR

Sequences:

>Translated_149_residues
MGMIDKFWMQLAYEQAVIARNEGEVPVGAVLVSKDNQLLGVGRNVIEKSHDPSDHAEIRAIRQASRKLNNHRLLDTTLYV
TLEPCVMCAGLMVHARIKRLVFATRDFKAGAAGSIFNVLHALNHSVLIDEGIMQAECSQLLSDFFRKLR
>Mature_148_residues
GMIDKFWMQLAYEQAVIARNEGEVPVGAVLVSKDNQLLGVGRNVIEKSHDPSDHAEIRAIRQASRKLNNHRLLDTTLYVT
LEPCVMCAGLMVHARIKRLVFATRDFKAGAAGSIFNVLHALNHSVLIDEGIMQAECSQLLSDFFRKLR

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=150, Percent_Identity=30.6666666666667, Blast_Score=76, Evalue=1e-14,
Organism=Escherichia coli, GI145693172, Length=146, Percent_Identity=56.1643835616438, Blast_Score=160, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI17541138, Length=148, Percent_Identity=31.7567567567568, Blast_Score=80, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17554608, Length=97, Percent_Identity=35.0515463917526, Blast_Score=70, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6325319, Length=143, Percent_Identity=31.4685314685315, Blast_Score=74, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6322425, Length=151, Percent_Identity=31.1258278145695, Blast_Score=62, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21355527, Length=145, Percent_Identity=30.3448275862069, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 16673; Mature: 16541

Theoretical pI: Translated: 8.51; Mature: 8.51

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGMIDKFWMQLAYEQAVIARNEGEVPVGAVLVSKDNQLLGVGRNVIEKSHDPSDHAEIRA
CCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEECCCHHHHHCCCCCCHHHHHHH
IRQASRKLNNHRLLDTTLYVTLEPCVMCAGLMVHARIKRLVFATRDFKAGAAGSIFNVLH
HHHHHHHHCCCEEEHHHEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
ALNHSVLIDEGIMQAECSQLLSDFFRKLR
HHCCCHHHHCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GMIDKFWMQLAYEQAVIARNEGEVPVGAVLVSKDNQLLGVGRNVIEKSHDPSDHAEIRA
CCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEECCCHHHHHCCCCCCHHHHHHH
IRQASRKLNNHRLLDTTLYVTLEPCVMCAGLMVHARIKRLVFATRDFKAGAAGSIFNVLH
HHHHHHHHCCCEEEHHHEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
ALNHSVLIDEGIMQAECSQLLSDFFRKLR
HHCCCHHHHCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]