Click here to switch to the map view.

The map label for this gene is yfdZ [H]

Identifier: 54294500

GI number: 54294500

Start: 1748970

End: 1750163

Strand: Reverse

Name: yfdZ [H]

Synonym: lpl1569

Alternate gene names: 54294500

Gene position: 1750163-1748970 (Counterclockwise)

Preceding gene: 54294502

Following gene: 54294499

Centisome position: 52.31

GC content: 40.2

Gene sequence:

>1194_bases
ATGAGTCAATTTCCACGCATTAAACGCTTACCCCCTTATGTATTTAATACAATAAACCAGCTTAAGATGGAAGCGCGGGC
GCGAGGAGAGGACATTATAGACTTTGGCATGGGGAATCCTGATCAACCAACTCCACCTCATATTGTTAATAAGCTTATAG
AGGTTGCTCAAAGGCCTGATACACATCGATATTCAATGTCGAAAGGAATTCCGAGATTACGTCGAGCGATGGCAACTTGG
TATCTTCGACATTATGATGTTCATCTGGACAGTGAAAAACAAATATTAGCTACAATAGGATCTAAAGAGGGGCTTGCACA
TTTGGCTTTGGCAATTTCAGGTCCAGGTGATACGGTGCTTGTTCCTGACCCTGCTTATCCTATCCATACCTACGGATTTA
TAATTGCGGGTGCTAATGTAAAGCAAATTCCTTTAATCGATGAAGTTCAATTTTTGGCTGCAGTAGAAGATGCTATTAAC
AGAACCTGGCCAAAACCCAAAGCCTTGGTTTTGAATTTTCCGGCAAATCCAAGTACTCACTGTGTCGAATATGAGTTTTT
TGAAAAGGTGGTTGATCTTGCCAAGCGTAATAACATTTGGATTATTCATGATTTAGCCTACGCAGATATAGTTTTTGATG
GGTATAAAGCCCCTTCGATTTTACAAGTTCCTGGTGCCATAGACATTGCAATTGAAACTTACTCAATGTCCAAATCTTAT
AATATGCCTGGTTGGCGTGTTGGGTTTGCTTGTGGTAATGAAGAGTTAGTAGCTGCCTTGACACGTATAAAATCTTACTT
GGATTACGGTACTTTTACTCCCATTCAGGTTGCTGCAATTACAGCATTGGAGGGCCCTGATGATTGTGTGTTGGAAATAA
GAAATCTTTATGAAAAACGACGCAATCTTTTATGTGATGGACTGAATGACATTGGTTGGGAAGTGAGCAAGCCTAAAGGG
ACCATGTTTGTTTGGGCGCCTATTCCTCTCAATTACCGCGCTATGGGGTCTCTTGAGTTCAGTAAATATTTATTGAAAGA
AGCACAAGTTGCTGTTTCACCTGGTATAGGTTTTGGACAGCAAGGGGATGGTTATGTCCGATTCGGCTTAATTGAAAATA
AAGACAGAATAAGACAAGCCTTGAGAAATATAAAAGCTCTGTTTAAAAGAGATGGTTTACTGAAGGCTATTTAG

Upstream 100 bases:

>100_bases
TTGCACTGCATGTTGCTCTGCGGTTTCTAGATTGATATTCATGATTTTAAAAGGTTCATTAGTTTATAATGGCTAACAGT
ATATCACAGAGGTCAATATT

Downstream 100 bases:

>100_bases
TGCAATGGATGTCATTATAAACACAGAGAGCAGCTGTGATAGCAAAGAGGGCAAATTATTAAAATCGCAAGGTTTGGCGG
TACTTAATTTATTAGCATGC

Product: aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 397; Mature: 396

Protein sequence:

>397_residues
MSQFPRIKRLPPYVFNTINQLKMEARARGEDIIDFGMGNPDQPTPPHIVNKLIEVAQRPDTHRYSMSKGIPRLRRAMATW
YLRHYDVHLDSEKQILATIGSKEGLAHLALAISGPGDTVLVPDPAYPIHTYGFIIAGANVKQIPLIDEVQFLAAVEDAIN
RTWPKPKALVLNFPANPSTHCVEYEFFEKVVDLAKRNNIWIIHDLAYADIVFDGYKAPSILQVPGAIDIAIETYSMSKSY
NMPGWRVGFACGNEELVAALTRIKSYLDYGTFTPIQVAAITALEGPDDCVLEIRNLYEKRRNLLCDGLNDIGWEVSKPKG
TMFVWAPIPLNYRAMGSLEFSKYLLKEAQVAVSPGIGFGQQGDGYVRFGLIENKDRIRQALRNIKALFKRDGLLKAI

Sequences:

>Translated_397_residues
MSQFPRIKRLPPYVFNTINQLKMEARARGEDIIDFGMGNPDQPTPPHIVNKLIEVAQRPDTHRYSMSKGIPRLRRAMATW
YLRHYDVHLDSEKQILATIGSKEGLAHLALAISGPGDTVLVPDPAYPIHTYGFIIAGANVKQIPLIDEVQFLAAVEDAIN
RTWPKPKALVLNFPANPSTHCVEYEFFEKVVDLAKRNNIWIIHDLAYADIVFDGYKAPSILQVPGAIDIAIETYSMSKSY
NMPGWRVGFACGNEELVAALTRIKSYLDYGTFTPIQVAAITALEGPDDCVLEIRNLYEKRRNLLCDGLNDIGWEVSKPKG
TMFVWAPIPLNYRAMGSLEFSKYLLKEAQVAVSPGIGFGQQGDGYVRFGLIENKDRIRQALRNIKALFKRDGLLKAI
>Mature_396_residues
SQFPRIKRLPPYVFNTINQLKMEARARGEDIIDFGMGNPDQPTPPHIVNKLIEVAQRPDTHRYSMSKGIPRLRRAMATWY
LRHYDVHLDSEKQILATIGSKEGLAHLALAISGPGDTVLVPDPAYPIHTYGFIIAGANVKQIPLIDEVQFLAAVEDAINR
TWPKPKALVLNFPANPSTHCVEYEFFEKVVDLAKRNNIWIIHDLAYADIVFDGYKAPSILQVPGAIDIAIETYSMSKSYN
MPGWRVGFACGNEELVAALTRIKSYLDYGTFTPIQVAAITALEGPDDCVLEIRNLYEKRRNLLCDGLNDIGWEVSKPKGT
MFVWAPIPLNYRAMGSLEFSKYLLKEAQVAVSPGIGFGQQGDGYVRFGLIENKDRIRQALRNIKALFKRDGLLKAI

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713256, Length=387, Percent_Identity=25.3229974160207, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI56713254, Length=384, Percent_Identity=24.7395833333333, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI95147551, Length=386, Percent_Identity=21.5025906735751, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI169881279, Length=386, Percent_Identity=21.5025906735751, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI169881281, Length=236, Percent_Identity=22.8813559322034, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI4507369, Length=346, Percent_Identity=22.5433526011561, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI1788722, Length=394, Percent_Identity=64.4670050761421, Blast_Score=540, Evalue=1e-155,
Organism=Escherichia coli, GI1786816, Length=343, Percent_Identity=27.1137026239067, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1788627, Length=348, Percent_Identity=24.4252873563218, Blast_Score=76, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI71994476, Length=393, Percent_Identity=24.6819338422392, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI71994472, Length=393, Percent_Identity=24.6819338422392, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17567369, Length=395, Percent_Identity=23.7974683544304, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17567663, Length=349, Percent_Identity=25.5014326647564, Blast_Score=87, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6322401, Length=401, Percent_Identity=21.1970074812968, Blast_Score=87, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6320317, Length=346, Percent_Identity=24.8554913294798, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI28573069, Length=420, Percent_Identity=24.7619047619048, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24646114, Length=420, Percent_Identity=24.7619047619048, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI28573067, Length=420, Percent_Identity=24.7619047619048, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI28573065, Length=420, Percent_Identity=24.7619047619048, Blast_Score=120, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 44546; Mature: 44415

Theoretical pI: Translated: 8.52; Mature: 8.52

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQFPRIKRLPPYVFNTINQLKMEARARGEDIIDFGMGNPDQPTPPHIVNKLIEVAQRPD
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHHHHHHHCCC
THRYSMSKGIPRLRRAMATWYLRHYDVHLDSEKQILATIGSKEGLAHLALAISGPGDTVL
CCHHHHHCCCHHHHHHHHHHHHHHEEEEECCCCCEEECCCCCCCCEEEEEEEECCCCEEE
VPDPAYPIHTYGFIIAGANVKQIPLIDEVQFLAAVEDAINRTWPKPKALVLNFPANPSTH
ECCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCC
CVEYEFFEKVVDLAKRNNIWIIHDLAYADIVFDGYKAPSILQVPGAIDIAIETYSMSKSY
EEEHHHHHHHHHHHHCCCEEEEEECCEEEEEECCCCCCCEEECCCEEEEEEEEEECCCCC
NMPGWRVGFACGNEELVAALTRIKSYLDYGTFTPIQVAAITALEGPDDCVLEIRNLYEKR
CCCCEEEEEEECCHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHH
RNLLCDGLNDIGWEVSKPKGTMFVWAPIPLNYRAMGSLEFSKYLLKEAQVAVSPGIGFGQ
HHHHHCCCCCCCCEEECCCCCEEEEECCCCCEEEECCHHHHHHHHHHHHEEECCCCCCCC
QGDGYVRFGLIENKDRIRQALRNIKALFKRDGLLKAI
CCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCCHHCC
>Mature Secondary Structure 
SQFPRIKRLPPYVFNTINQLKMEARARGEDIIDFGMGNPDQPTPPHIVNKLIEVAQRPD
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHHHHHHHCCC
THRYSMSKGIPRLRRAMATWYLRHYDVHLDSEKQILATIGSKEGLAHLALAISGPGDTVL
CCHHHHHCCCHHHHHHHHHHHHHHEEEEECCCCCEEECCCCCCCCEEEEEEEECCCCEEE
VPDPAYPIHTYGFIIAGANVKQIPLIDEVQFLAAVEDAINRTWPKPKALVLNFPANPSTH
ECCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCC
CVEYEFFEKVVDLAKRNNIWIIHDLAYADIVFDGYKAPSILQVPGAIDIAIETYSMSKSY
EEEHHHHHHHHHHHHCCCEEEEEECCEEEEEECCCCCCCEEECCCEEEEEEEEEECCCCC
NMPGWRVGFACGNEELVAALTRIKSYLDYGTFTPIQVAAITALEGPDDCVLEIRNLYEKR
CCCCEEEEEEECCHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHH
RNLLCDGLNDIGWEVSKPKGTMFVWAPIPLNYRAMGSLEFSKYLLKEAQVAVSPGIGFGQ
HHHHHCCCCCCCCEEECCCCCEEEEECCCCCEEEECCHHHHHHHHHHHHEEECCCCCCCC
QGDGYVRFGLIENKDRIRQALRNIKALFKRDGLLKAI
CCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCCHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]