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The map label for this gene is aroA [H]

Identifier: 54294305

GI number: 54294305

Start: 1529010

End: 1530311

Strand: Direct

Name: aroA [H]

Synonym: lpl1370

Alternate gene names: 54294305

Gene position: 1529010-1530311 (Clockwise)

Preceding gene: 54294304

Following gene: 54294306

Centisome position: 45.7

GC content: 41.17

Gene sequence:

>1302_bases
ATGTTGAATTTTATAAGTAAACCAGTAGGCTGCCTTAAGGGCGAAATCACAGTACCTGGAGATAAATCCATTTCTCATCG
TTCTATTATTTTTGGCGCGATTGCTATTGGAACTTCAGTAATCGATGGCTTTTTAGATGGTGAAGATTGCATAGCCACCC
TTAAAGCATTCCAATCAATGGGTGTTAGGATAGAGGGTCCTGATAAGCAACGTGTCATTATTCATGGGGTTGGTAAATAT
GGTTTAAAACAACCTCAAAATATTATTGATTGTGGCAACTCAGGCACCAGTATGCGCTTGCTGGCTGGATTGCTTGCAGC
ACAACAATTTGATAGCCAGTTAACGGGAGACGAAAGTTTACTTAAACGCCCAATGTTAAGAATTAGTAGACCCTTAAGTC
AAATGGGCGCAGACGTTACTACTCAGGATGGGAAACCGCCTATAGTAATCAAAGGCGGAAAAAAATTAAATGGAGTACAT
TATGTTATGCCGGAAGCCAGCGCTCAGGTAAAGTCGTGTTTGTTGTTAGCTGGTATGTATGCTGAAGGACAAACAAAAAT
AACTGAAAATGCAGTCAGTCGGGATCATACTGAAAGAATGTTAAGAACATTTTCTTATCCAGTTCAGATACAAGATGGTA
CTATCGTAATTGATCGTAATGGTGAGTGCCATGGAACTCGTCTGAATATCCCGGGAGACATTTCATCTGCTGCATTTTTT
ATTGTTGCAGCTTCTATTACCCCAGACTCCGATGTTTTAATTCGTAATGTAGGCATTAATCCTACACGAACTGGCATTAT
TCATATTTTAACTGAAATGGGAGCGGACATAAGAATTTTGAATCAACGTGCCTATGGAGAGGAACCAGTTGCTGATTTGC
ATATCAGATATTCCCAATTAAAAGGAATCGATATTCCTGTCTCTATGGTGCCTTTGGCGATTGATGAATTCCCGGTTATT
TTTATTGCAGCTGCTTGCGCACAAGGGAAAACCACTCTTCATGGAGCTAAAGAGCTGCGCTTGAAGGAAAGTGATCGTAT
TGGCGCGATGGTGGATGGCTTAAATCAATTGGGAGTTCATGCTGAGGGTTTTGATGATGGAATATTGATAGAGGGTGGAA
GTATACAGGGTGGTGAGGTTAATAGTCGAGGAGATCACCGTATTGCCATGTCATTTGCCATTGCTGGCGCTGTCGCCAGT
GCTCCTGTAACGATTAAAAACTGCGCCAATGTTGCAACTTCATTTCCATCTTTTGTTACTACCGCTAACATGCTTCATTT
TCAGATAGAGGAATACAGCTGA

Upstream 100 bases:

>100_bases
GAGGATTGCGCGCCAGTTTGTACAATGCCATGCCTATGGCTGGAGTTGATGCCCTCATTGAGTTTATGTCTGAATTTGCA
AAAGAAAATGGTTAATAAGT

Downstream 100 bases:

>100_bases
TGGTTTTTAATAATGAGGTTCCTGTCATTACGTTGGATGGTCCAAGTGGAACAGGAAAGGGGACAATTTGTCATTTGGTA
GCCAAGAGACTACATTGGAA

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MLNFISKPVGCLKGEITVPGDKSISHRSIIFGAIAIGTSVIDGFLDGEDCIATLKAFQSMGVRIEGPDKQRVIIHGVGKY
GLKQPQNIIDCGNSGTSMRLLAGLLAAQQFDSQLTGDESLLKRPMLRISRPLSQMGADVTTQDGKPPIVIKGGKKLNGVH
YVMPEASAQVKSCLLLAGMYAEGQTKITENAVSRDHTERMLRTFSYPVQIQDGTIVIDRNGECHGTRLNIPGDISSAAFF
IVAASITPDSDVLIRNVGINPTRTGIIHILTEMGADIRILNQRAYGEEPVADLHIRYSQLKGIDIPVSMVPLAIDEFPVI
FIAAACAQGKTTLHGAKELRLKESDRIGAMVDGLNQLGVHAEGFDDGILIEGGSIQGGEVNSRGDHRIAMSFAIAGAVAS
APVTIKNCANVATSFPSFVTTANMLHFQIEEYS

Sequences:

>Translated_433_residues
MLNFISKPVGCLKGEITVPGDKSISHRSIIFGAIAIGTSVIDGFLDGEDCIATLKAFQSMGVRIEGPDKQRVIIHGVGKY
GLKQPQNIIDCGNSGTSMRLLAGLLAAQQFDSQLTGDESLLKRPMLRISRPLSQMGADVTTQDGKPPIVIKGGKKLNGVH
YVMPEASAQVKSCLLLAGMYAEGQTKITENAVSRDHTERMLRTFSYPVQIQDGTIVIDRNGECHGTRLNIPGDISSAAFF
IVAASITPDSDVLIRNVGINPTRTGIIHILTEMGADIRILNQRAYGEEPVADLHIRYSQLKGIDIPVSMVPLAIDEFPVI
FIAAACAQGKTTLHGAKELRLKESDRIGAMVDGLNQLGVHAEGFDDGILIEGGSIQGGEVNSRGDHRIAMSFAIAGAVAS
APVTIKNCANVATSFPSFVTTANMLHFQIEEYS
>Mature_433_residues
MLNFISKPVGCLKGEITVPGDKSISHRSIIFGAIAIGTSVIDGFLDGEDCIATLKAFQSMGVRIEGPDKQRVIIHGVGKY
GLKQPQNIIDCGNSGTSMRLLAGLLAAQQFDSQLTGDESLLKRPMLRISRPLSQMGADVTTQDGKPPIVIKGGKKLNGVH
YVMPEASAQVKSCLLLAGMYAEGQTKITENAVSRDHTERMLRTFSYPVQIQDGTIVIDRNGECHGTRLNIPGDISSAAFF
IVAASITPDSDVLIRNVGINPTRTGIIHILTEMGADIRILNQRAYGEEPVADLHIRYSQLKGIDIPVSMVPLAIDEFPVI
FIAAACAQGKTTLHGAKELRLKESDRIGAMVDGLNQLGVHAEGFDDGILIEGGSIQGGEVNSRGDHRIAMSFAIAGAVAS
APVTIKNCANVATSFPSFVTTANMLHFQIEEYS

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=432, Percent_Identity=30.0925925925926, Blast_Score=138, Evalue=6e-34,
Organism=Saccharomyces cerevisiae, GI6320332, Length=431, Percent_Identity=27.8422273781903, Blast_Score=88, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 46321; Mature: 46321

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS00104 EPSP_SYNTHASE_1 ; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNFISKPVGCLKGEITVPGDKSISHRSIIFGAIAIGTSVIDGFLDGEDCIATLKAFQSM
CCCCCCCCHHHHCCCEECCCCCCCCCHHHEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHC
GVRIEGPDKQRVIIHGVGKYGLKQPQNIIDCGNSGTSMRLLAGLLAAQQFDSQLTGDESL
CCEEECCCCCEEEEEECCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHH
LKRPMLRISRPLSQMGADVTTQDGKPPIVIKGGKKLNGVHYVMPEASAQVKSCLLLAGMY
HHHHHHHHHCCHHHHCCCCCCCCCCCCEEEECCCEECCEEEECCCCHHHHHHHHHHHHHC
AEGQTKITENAVSRDHTERMLRTFSYPVQIQDGTIVIDRNGECHGTRLNIPGDISSAAFF
CCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEEECCCCCCCEEECCCCCCCCCEEE
IVAASITPDSDVLIRNVGINPTRTGIIHILTEMGADIRILNQRAYGEEPVADLHIRYSQL
EEEEECCCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHEEEHHHH
KGIDIPVSMVPLAIDEFPVIFIAAACAQGKTTLHGAKELRLKESDRIGAMVDGLNQLGVH
CCCCCCHHHHCEECCCCCEEEEEEHHCCCCCCCCCHHHHEECCCCCHHHHHHCHHHHCCC
AEGFDDGILIEGGSIQGGEVNSRGDHRIAMSFAIAGAVASAPVTIKNCANVATSFPSFVT
CCCCCCCEEEECCCCCCCCCCCCCCCEEEEEEHHHHHHHCCCEEHHHHHHHHHCCCHHHH
TANMLHFQIEEYS
HCEEEEEEEECCC
>Mature Secondary Structure
MLNFISKPVGCLKGEITVPGDKSISHRSIIFGAIAIGTSVIDGFLDGEDCIATLKAFQSM
CCCCCCCCHHHHCCCEECCCCCCCCCHHHEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHC
GVRIEGPDKQRVIIHGVGKYGLKQPQNIIDCGNSGTSMRLLAGLLAAQQFDSQLTGDESL
CCEEECCCCCEEEEEECCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHH
LKRPMLRISRPLSQMGADVTTQDGKPPIVIKGGKKLNGVHYVMPEASAQVKSCLLLAGMY
HHHHHHHHHCCHHHHCCCCCCCCCCCCEEEECCCEECCEEEECCCCHHHHHHHHHHHHHC
AEGQTKITENAVSRDHTERMLRTFSYPVQIQDGTIVIDRNGECHGTRLNIPGDISSAAFF
CCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEEECCCCCCCEEECCCCCCCCCEEE
IVAASITPDSDVLIRNVGINPTRTGIIHILTEMGADIRILNQRAYGEEPVADLHIRYSQL
EEEEECCCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHEEEHHHH
KGIDIPVSMVPLAIDEFPVIFIAAACAQGKTTLHGAKELRLKESDRIGAMVDGLNQLGVH
CCCCCCHHHHCEECCCCCEEEEEEHHCCCCCCCCCHHHHEECCCCCHHHHHHCHHHHCCC
AEGFDDGILIEGGSIQGGEVNSRGDHRIAMSFAIAGAVASAPVTIKNCANVATSFPSFVT
CCCCCCCEEEECCCCCCCCCCCCCCCEEEEEEHHHHHHHCCCEEHHHHHHHHHCCCHHHH
TANMLHFQIEEYS
HCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA