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The map label for this gene is serC [H]

Identifier: 54294304

GI number: 54294304

Start: 1527916

End: 1529004

Strand: Direct

Name: serC [H]

Synonym: lpl1369

Alternate gene names: 54294304

Gene position: 1527916-1529004 (Clockwise)

Preceding gene: 54294303

Following gene: 54294305

Centisome position: 45.67

GC content: 37.65

Gene sequence:

>1089_bases
ATGAATAGCAGGGTTTTCAATTTTGGAGCTGGCCCTGCCATGCTGCCTGAGGAGATATTAAAAGAGGCTCAAGAGGAATT
TCTTAATTGGCGTAATACCGGCATGTCTATACTTGAAATAGGGCATAGAACACCGGAAATCATTAGTCTTTTAAGTACCG
CAGAGCAATCGTTAAGAGAACTGTTAAATATCCCCAAAAATTATCATGTATTATTTTTGGGGGGGGCAGCTCGGACACAA
TTTGCCATGATTCCTATGAATTTATTACGGCCAGGAGATGATGCGGCTTATTTTATTACGGGAATCTGGTCTAAGATGGC
TTATCATGAAGCGAATCTTCTAAAAAAAGCATATTACCTTAGCAGTGAAGAGAAAGAAGGATTTGTATCAATTCCTGACT
ATCAAAAGTGGGAGTTAAAAAGTAATACAGCCTATGTCTATTATACCCCAAATGAAACAATTAATGGAGTCAGATTTCCT
TATGTTCCTAAAACAGGAGGGGTTCCTTTAGTCGCGGATATGACTTCTTGTTTGCTGAGCGAGCCGATAAATATTAATCA
ATATGGTTTGATTTTTGCTGGTGCACAGAAGAACATTGCCAATGCAGGTTTAACTGTAGTTATCATTCATGAGGAATTAC
TAAAAAACCAACCTGAACCAGTGATTCCTACCATGTTGAATTATAAAAATCATGCCGAACATCGCTCCTTATATGCTACA
CCACCAGTATTTAATTGTTATTTGGCAAGTAAAATGTTCGAGTGGATAAAAACTCAGGGAGGTATAGAAGGCTTATTTCA
AAGGAATTGTTTGAAAGCCGCGAAGTTATATCAATATCTTGATTCAACTGATTTTTATCTAACTCCAGTATTTAAAGAAG
CTCGTTCTATAATGAATATTTGTTTTTCCCTCTGTTATCCTGATTTGGAACATAAATTCCTCGATATGGCTAATGAGCGT
GGGTTAAAGGCTTTAAAAGGTCATCGTTTCACTGGAGGATTGCGCGCCAGTTTGTACAATGCCATGCCTATGGCTGGAGT
TGATGCCCTCATTGAGTTTATGTCTGAATTTGCAAAAGAAAATGGTTAA

Upstream 100 bases:

>100_bases
AGTTCTGGTGAGGCAGTTGTTGGAATGCAAAAAATTGTAGATCTTGGAGAAGAATTAGAAGAGGCAGAAGACTCATCCCT
TAATGCTGAAGACAGCAGTG

Downstream 100 bases:

>100_bases
TAAGTATGTTGAATTTTATAAGTAAACCAGTAGGCTGCCTTAAGGGCGAAATCACAGTACCTGGAGATAAATCCATTTCT
CATCGTTCTATTATTTTTGG

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT [H]

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MNSRVFNFGAGPAMLPEEILKEAQEEFLNWRNTGMSILEIGHRTPEIISLLSTAEQSLRELLNIPKNYHVLFLGGAARTQ
FAMIPMNLLRPGDDAAYFITGIWSKMAYHEANLLKKAYYLSSEEKEGFVSIPDYQKWELKSNTAYVYYTPNETINGVRFP
YVPKTGGVPLVADMTSCLLSEPININQYGLIFAGAQKNIANAGLTVVIIHEELLKNQPEPVIPTMLNYKNHAEHRSLYAT
PPVFNCYLASKMFEWIKTQGGIEGLFQRNCLKAAKLYQYLDSTDFYLTPVFKEARSIMNICFSLCYPDLEHKFLDMANER
GLKALKGHRFTGGLRASLYNAMPMAGVDALIEFMSEFAKENG

Sequences:

>Translated_362_residues
MNSRVFNFGAGPAMLPEEILKEAQEEFLNWRNTGMSILEIGHRTPEIISLLSTAEQSLRELLNIPKNYHVLFLGGAARTQ
FAMIPMNLLRPGDDAAYFITGIWSKMAYHEANLLKKAYYLSSEEKEGFVSIPDYQKWELKSNTAYVYYTPNETINGVRFP
YVPKTGGVPLVADMTSCLLSEPININQYGLIFAGAQKNIANAGLTVVIIHEELLKNQPEPVIPTMLNYKNHAEHRSLYAT
PPVFNCYLASKMFEWIKTQGGIEGLFQRNCLKAAKLYQYLDSTDFYLTPVFKEARSIMNICFSLCYPDLEHKFLDMANER
GLKALKGHRFTGGLRASLYNAMPMAGVDALIEFMSEFAKENG
>Mature_362_residues
MNSRVFNFGAGPAMLPEEILKEAQEEFLNWRNTGMSILEIGHRTPEIISLLSTAEQSLRELLNIPKNYHVLFLGGAARTQ
FAMIPMNLLRPGDDAAYFITGIWSKMAYHEANLLKKAYYLSSEEKEGFVSIPDYQKWELKSNTAYVYYTPNETINGVRFP
YVPKTGGVPLVADMTSCLLSEPININQYGLIFAGAQKNIANAGLTVVIIHEELLKNQPEPVIPTMLNYKNHAEHRSLYAT
PPVFNCYLASKMFEWIKTQGGIEGLFQRNCLKAAKLYQYLDSTDFYLTPVFKEARSIMNICFSLCYPDLEHKFLDMANER
GLKALKGHRFTGGLRASLYNAMPMAGVDALIEFMSEFAKENG

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine [H]

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily [H]

Homologues:

Organism=Homo sapiens, GI17402893, Length=361, Percent_Identity=41.2742382271468, Blast_Score=287, Evalue=9e-78,
Organism=Homo sapiens, GI10863955, Length=357, Percent_Identity=36.1344537815126, Blast_Score=241, Evalue=6e-64,
Organism=Escherichia coli, GI1787136, Length=362, Percent_Identity=42.5414364640884, Blast_Score=311, Evalue=3e-86,
Organism=Caenorhabditis elegans, GI17506897, Length=365, Percent_Identity=40.8219178082192, Blast_Score=294, Evalue=6e-80,
Organism=Saccharomyces cerevisiae, GI6324758, Length=388, Percent_Identity=36.8556701030928, Blast_Score=247, Evalue=2e-66,
Organism=Drosophila melanogaster, GI21356589, Length=363, Percent_Identity=40.2203856749311, Blast_Score=279, Evalue=2e-75,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR022278
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.52 [H]

Molecular weight: Translated: 40908; Mature: 40908

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSRVFNFGAGPAMLPEEILKEAQEEFLNWRNTGMSILEIGHRTPEIISLLSTAEQSLRE
CCCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHH
LLNIPKNYHVLFLGGAARTQFAMIPMNLLRPGDDAAYFITGIWSKMAYHEANLLKKAYYL
HHCCCCCEEEEEEECCCCCEEEECCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
SSEEKEGFVSIPDYQKWELKSNTAYVYYTPNETINGVRFPYVPKTGGVPLVADMTSCLLS
CCCCCCCCEECCCCCCEEECCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
EPININQYGLIFAGAQKNIANAGLTVVIIHEELLKNQPEPVIPTMLNYKNHAEHRSLYAT
CCCCCCCCEEEEECCCCCCCCCCCEEEEEEHHHHCCCCCCCCHHHHCCCCCHHHCCEECC
PPVFNCYLASKMFEWIKTQGGIEGLFQRNCLKAAKLYQYLDSTDFYLTPVFKEARSIMNI
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHH
CFSLCYPDLEHKFLDMANERGLKALKGHRFTGGLRASLYNAMPMAGVDALIEFMSEFAKE
HHHHHCCCHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHC
NG
CC
>Mature Secondary Structure
MNSRVFNFGAGPAMLPEEILKEAQEEFLNWRNTGMSILEIGHRTPEIISLLSTAEQSLRE
CCCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHH
LLNIPKNYHVLFLGGAARTQFAMIPMNLLRPGDDAAYFITGIWSKMAYHEANLLKKAYYL
HHCCCCCEEEEEEECCCCCEEEECCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
SSEEKEGFVSIPDYQKWELKSNTAYVYYTPNETINGVRFPYVPKTGGVPLVADMTSCLLS
CCCCCCCCEECCCCCCEEECCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
EPININQYGLIFAGAQKNIANAGLTVVIIHEELLKNQPEPVIPTMLNYKNHAEHRSLYAT
CCCCCCCCEEEEECCCCCCCCCCCEEEEEEHHHHCCCCCCCCHHHHCCCCCHHHCCEECC
PPVFNCYLASKMFEWIKTQGGIEGLFQRNCLKAAKLYQYLDSTDFYLTPVFKEARSIMNI
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHH
CFSLCYPDLEHKFLDMANERGLKALKGHRFTGGLRASLYNAMPMAGVDALIEFMSEFAKE
HHHHHCCCHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHC
NG
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA