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The map label for this gene is hbpA [H]

Identifier: 54293932

GI number: 54293932

Start: 1113473

End: 1115629

Strand: Direct

Name: hbpA [H]

Synonym: lpl0988

Alternate gene names: 54293932

Gene position: 1113473-1115629 (Clockwise)

Preceding gene: 54293931

Following gene: 54293933

Centisome position: 33.28

GC content: 37.74

Gene sequence:

>2157_bases
ATGTTATTTTTAATGCCTTGCTGTGTCAATTTGGCTTATGGCAGTTCTTGGGTATTCAATAATCCTTATCCAGAGAGCGA
GGCCAATGAAAATATTTATTATTCTTCTTTTAATGAACAGCCAAAAACTCTGGATCCAGCACGCTCCTATTCTTCCAATG
AATATCTTTTCATAGCCCAGATCTATGAGCCACTGCTGGAATATGATTACTATAAAAGACCCTATGAATTAATCCCATTA
ACAGCTACCCGCTTACCACAGATTCGATATTTGGATGCCCAGGGAAATCCTGTTCCGGCAGGAGATAACACAAAGCCAGC
ATACAGTGTCTATACCATTCAGATAAAAAAAGGAATTTTATATCAACCTCATCCTGCTTTGGCTCAGAAGAAAGATGGCT
CTTATCGATATCATCACTTACCAGAAGATTATTTGGAAGAGCATGATATTAACAAGTTGTCAGATTTTAAATACACCGGT
ACAAGGGAGCTGATCATTGATGATTACATTTATCAAATTAAAAGATTGGCAAACCCTGCTGTGAGTTCTCCAATATATGG
ATTGATGAGCTATTATATTCTGGGCTTCAAGGAGTATGGAGATAGTCTTCCTAAAGGATTCGCCAATAAAAATTCTTTTA
TTGATTTACGTAAGTATCCTTTGCAGGGGGTTAAAAAATTAGATGATTACACCTTTGAGATTACCTTAAAGGGGCAATAT
ACACAATTTCTGTTTTGGTTAGCTATGCCCTTTTTTGCTCCGGTTCCTTGGGAAGCGGACTTATTTTATTCCCAAAAAGA
TATGGATGATAAAAACTTATCTTTTGGCTGGTATCCTATAGGTACAGGGCCTTTTATGCTGACTGAAAATAATCCCAATA
GAAGCATGATATTGGAGAGAAATCCTAATTTCAGAGAAGTGTATTTTCCTGTCAATGGTTCAGATGCCGATAGACGGGCA
GGTTATTTAACCAATCAGGGAAGGCGCTTGCCCTTAATTGATAAAGCCGTTTATACCCTTGAAAAGGAATCCATACCTCG
ATGGAATAAATTCTTGCAAGGCTACTATGATATGTCGGGGATAAGTGCTGACAGTTTTGATCAGGCTATTCATATTAATC
GCTTTGGAGAACCTATCCTTAGCCAGGAAATGAAAGATAAAAAAATATATTTAAGACAAACCCTGGAACCGTCTATCTAT
TATACTGGCTTTAATATGCTTGACAGCGTTGTTGGGGGCAATAGTAAAAGAGCACGAAAATTACGCCAGGCAATTTCTAT
TGCGGTGAATTTTGATGAAAATATTGCCATATTTTTTAATGGCCGAGGTATTCCGGCGCAAGGCCCTATTCCACCTGGTA
TCTTTGGGTACAAGGAAGGAAAAGAGGGTATTAATCCCTATGTTTATCAATGGGTGAATAATGCCAGGAAACGAAAATCC
TTAAAGGATGCGCAGAAGTTAATGGTTGAGGCAGGATATCCGGGAGGGATAGATCCGAAAACCGGGAAACACCTGATTCT
TCATTATGATGTCATGACGACAGGTGGACCTGATGATAAAGCAAGGCTTGACTGGATGCGAAAGCAATTTGCAAATATAG
GGATAGATTTGAATATTAGGGCGACTCTTTACAATCGTTTCCAGGAAAAGATGCGGATAGGTCATGCTCAAATATTTAGT
TGGGGCTGGAATGCCGATTATCCTGATCCCGAAAACTTTTTATTTTTGCTTTATGGGAAAAATGGAAAAGTAAAGTATGG
TGGTGAAAATGCATCAAATTATGAAAATCCTGAATTTGATAGATTGTTTAATTTGATGAAAAATCGCCCTAACGATCTAC
AAAGACAAAAACTGATTGATAAGATGTTAGCGATTGTCCGGTATGATGCTCCATGGGTATGGGGCATGCATTCTGAAGAC
TTTATTTTATCGCAAGATTGGGTATCTAATATAAAATCCAATACGATTTCTCTCAATACTCTAAAATATGTTTCTGTTAA
TGTACCTGAACGTAACCAACTGCGAAGATCCTGGAATCAACCGGTATTTTGGCCTTTAGGTGTGCTGTTTGGCCTATTGA
TTGCTTTGGTAATCCCTTTATTGATTACTTATTTAAAGAAAGAAAAACAGCCGGCAGAAAGAGTAAAATTAAAATGA

Upstream 100 bases:

>100_bases
GATAGGTAGCAATGAATCGGGTGAAGTAGGTATTTAAACCTGTAATAATGACTGATTGGCACGAGGGAAGTAAGTGCGGC
GATATTTGTTAATTCAATTC

Downstream 100 bases:

>100_bases
TTAAATACATACTCCGCAGAATTTTATATGCGATTCCAATTTTGTTTGGTATTAATCTTATTACTTTTGCATTGTTTTTC
ATGGTTAATTCTCCCGATGA

Product: hypothetical protein

Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]

Alternate protein names: Hemin-binding lipoprotein [H]

Number of amino acids: Translated: 718; Mature: 718

Protein sequence:

>718_residues
MLFLMPCCVNLAYGSSWVFNNPYPESEANENIYYSSFNEQPKTLDPARSYSSNEYLFIAQIYEPLLEYDYYKRPYELIPL
TATRLPQIRYLDAQGNPVPAGDNTKPAYSVYTIQIKKGILYQPHPALAQKKDGSYRYHHLPEDYLEEHDINKLSDFKYTG
TRELIIDDYIYQIKRLANPAVSSPIYGLMSYYILGFKEYGDSLPKGFANKNSFIDLRKYPLQGVKKLDDYTFEITLKGQY
TQFLFWLAMPFFAPVPWEADLFYSQKDMDDKNLSFGWYPIGTGPFMLTENNPNRSMILERNPNFREVYFPVNGSDADRRA
GYLTNQGRRLPLIDKAVYTLEKESIPRWNKFLQGYYDMSGISADSFDQAIHINRFGEPILSQEMKDKKIYLRQTLEPSIY
YTGFNMLDSVVGGNSKRARKLRQAISIAVNFDENIAIFFNGRGIPAQGPIPPGIFGYKEGKEGINPYVYQWVNNARKRKS
LKDAQKLMVEAGYPGGIDPKTGKHLILHYDVMTTGGPDDKARLDWMRKQFANIGIDLNIRATLYNRFQEKMRIGHAQIFS
WGWNADYPDPENFLFLLYGKNGKVKYGGENASNYENPEFDRLFNLMKNRPNDLQRQKLIDKMLAIVRYDAPWVWGMHSED
FILSQDWVSNIKSNTISLNTLKYVSVNVPERNQLRRSWNQPVFWPLGVLFGLLIALVIPLLITYLKKEKQPAERVKLK

Sequences:

>Translated_718_residues
MLFLMPCCVNLAYGSSWVFNNPYPESEANENIYYSSFNEQPKTLDPARSYSSNEYLFIAQIYEPLLEYDYYKRPYELIPL
TATRLPQIRYLDAQGNPVPAGDNTKPAYSVYTIQIKKGILYQPHPALAQKKDGSYRYHHLPEDYLEEHDINKLSDFKYTG
TRELIIDDYIYQIKRLANPAVSSPIYGLMSYYILGFKEYGDSLPKGFANKNSFIDLRKYPLQGVKKLDDYTFEITLKGQY
TQFLFWLAMPFFAPVPWEADLFYSQKDMDDKNLSFGWYPIGTGPFMLTENNPNRSMILERNPNFREVYFPVNGSDADRRA
GYLTNQGRRLPLIDKAVYTLEKESIPRWNKFLQGYYDMSGISADSFDQAIHINRFGEPILSQEMKDKKIYLRQTLEPSIY
YTGFNMLDSVVGGNSKRARKLRQAISIAVNFDENIAIFFNGRGIPAQGPIPPGIFGYKEGKEGINPYVYQWVNNARKRKS
LKDAQKLMVEAGYPGGIDPKTGKHLILHYDVMTTGGPDDKARLDWMRKQFANIGIDLNIRATLYNRFQEKMRIGHAQIFS
WGWNADYPDPENFLFLLYGKNGKVKYGGENASNYENPEFDRLFNLMKNRPNDLQRQKLIDKMLAIVRYDAPWVWGMHSED
FILSQDWVSNIKSNTISLNTLKYVSVNVPERNQLRRSWNQPVFWPLGVLFGLLIALVIPLLITYLKKEKQPAERVKLK
>Mature_718_residues
MLFLMPCCVNLAYGSSWVFNNPYPESEANENIYYSSFNEQPKTLDPARSYSSNEYLFIAQIYEPLLEYDYYKRPYELIPL
TATRLPQIRYLDAQGNPVPAGDNTKPAYSVYTIQIKKGILYQPHPALAQKKDGSYRYHHLPEDYLEEHDINKLSDFKYTG
TRELIIDDYIYQIKRLANPAVSSPIYGLMSYYILGFKEYGDSLPKGFANKNSFIDLRKYPLQGVKKLDDYTFEITLKGQY
TQFLFWLAMPFFAPVPWEADLFYSQKDMDDKNLSFGWYPIGTGPFMLTENNPNRSMILERNPNFREVYFPVNGSDADRRA
GYLTNQGRRLPLIDKAVYTLEKESIPRWNKFLQGYYDMSGISADSFDQAIHINRFGEPILSQEMKDKKIYLRQTLEPSIY
YTGFNMLDSVVGGNSKRARKLRQAISIAVNFDENIAIFFNGRGIPAQGPIPPGIFGYKEGKEGINPYVYQWVNNARKRKS
LKDAQKLMVEAGYPGGIDPKTGKHLILHYDVMTTGGPDDKARLDWMRKQFANIGIDLNIRATLYNRFQEKMRIGHAQIFS
WGWNADYPDPENFLFLLYGKNGKVKYGGENASNYENPEFDRLFNLMKNRPNDLQRQKLIDKMLAIVRYDAPWVWGMHSED
FILSQDWVSNIKSNTISLNTLKYVSVNVPERNQLRRSWNQPVFWPLGVLFGLLIALVIPLLITYLKKEKQPAERVKLK

Specific function: Important role in heme acquisition or metabolism [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=531, Percent_Identity=24.105461393597, Blast_Score=80, Evalue=4e-16,

Paralogues:

None

Copy number: 760 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2360 Molecules/Cell In: Stationary-Phase,

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 83325; Mature: 83325

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFLMPCCVNLAYGSSWVFNNPYPESEANENIYYSSFNEQPKTLDPARSYSSNEYLFIAQ
CEEEECCHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCHHHCCCCCCEEEEHH
IYEPLLEYDYYKRPYELIPLTATRLPQIRYLDAQGNPVPAGDNTKPAYSVYTIQIKKGIL
HHHHHHHHHHHCCCCEEEEECHHCCCCEEEECCCCCCCCCCCCCCCCEEEEEEEEECCCE
YQPHPALAQKKDGSYRYHHLPEDYLEEHDINKLSDFKYTGTRELIIDDYIYQIKRLANPA
ECCCCHHHCCCCCCEEECCCCHHHHHHCCCCHHHCCEECCCHHHHHHHHHHHHHHHCCCC
VSSPIYGLMSYYILGFKEYGDSLPKGFANKNSFIDLRKYPLQGVKKLDDYTFEITLKGQY
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEHHHCCHHHHHHCCCEEEEEEECCCH
TQFLFWLAMPFFAPVPWEADLFYSQKDMDDKNLSFGWYPIGTGPFMLTENNPNRSMILER
HHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCEEEEEECCCCCEEEECCCCCCEEEEEC
NPNFREVYFPVNGSDADRRAGYLTNQGRRLPLIDKAVYTLEKESIPRWNKFLQGYYDMSG
CCCCEEEEEECCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCC
ISADSFDQAIHINRFGEPILSQEMKDKKIYLRQTLEPSIYYTGFNMLDSVVGGNSKRARK
CCCCCHHCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHCCCHHHHHH
LRQAISIAVNFDENIAIFFNGRGIPAQGPIPPGIFGYKEGKEGINPYVYQWVNNARKRKS
HHHHHEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
LKDAQKLMVEAGYPGGIDPKTGKHLILHYDVMTTGGPDDKARLDWMRKQFANIGIDLNIR
HHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEH
ATLYNRFQEKMRIGHAQIFSWGWNADYPDPENFLFLLYGKNGKVKYGGENASNYENPEFD
HHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEEEECCCCEEEECCCCCCCCCCCCHH
RLFNLMKNRPNDLQRQKLIDKMLAIVRYDAPWVWGMHSEDFILSQDWVSNIKSNTISLNT
HHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCCCEECHHHHHHHCCCEEEEEE
LKYVSVNVPERNQLRRSWNQPVFWPLGVLFGLLIALVIPLLITYLKKEKQPAERVKLK
EEEEEECCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCC
>Mature Secondary Structure
MLFLMPCCVNLAYGSSWVFNNPYPESEANENIYYSSFNEQPKTLDPARSYSSNEYLFIAQ
CEEEECCHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCHHHCCCCCCEEEEHH
IYEPLLEYDYYKRPYELIPLTATRLPQIRYLDAQGNPVPAGDNTKPAYSVYTIQIKKGIL
HHHHHHHHHHHCCCCEEEEECHHCCCCEEEECCCCCCCCCCCCCCCCEEEEEEEEECCCE
YQPHPALAQKKDGSYRYHHLPEDYLEEHDINKLSDFKYTGTRELIIDDYIYQIKRLANPA
ECCCCHHHCCCCCCEEECCCCHHHHHHCCCCHHHCCEECCCHHHHHHHHHHHHHHHCCCC
VSSPIYGLMSYYILGFKEYGDSLPKGFANKNSFIDLRKYPLQGVKKLDDYTFEITLKGQY
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEHHHCCHHHHHHCCCEEEEEEECCCH
TQFLFWLAMPFFAPVPWEADLFYSQKDMDDKNLSFGWYPIGTGPFMLTENNPNRSMILER
HHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCEEEEEECCCCCEEEECCCCCCEEEEEC
NPNFREVYFPVNGSDADRRAGYLTNQGRRLPLIDKAVYTLEKESIPRWNKFLQGYYDMSG
CCCCEEEEEECCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCC
ISADSFDQAIHINRFGEPILSQEMKDKKIYLRQTLEPSIYYTGFNMLDSVVGGNSKRARK
CCCCCHHCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHCCCHHHHHH
LRQAISIAVNFDENIAIFFNGRGIPAQGPIPPGIFGYKEGKEGINPYVYQWVNNARKRKS
HHHHHEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
LKDAQKLMVEAGYPGGIDPKTGKHLILHYDVMTTGGPDDKARLDWMRKQFANIGIDLNIR
HHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEH
ATLYNRFQEKMRIGHAQIFSWGWNADYPDPENFLFLLYGKNGKVKYGGENASNYENPEFD
HHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEEEECCCCEEEECCCCCCCCCCCCHH
RLFNLMKNRPNDLQRQKLIDKMLAIVRYDAPWVWGMHSEDFILSQDWVSNIKSNTISLNT
HHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCCCEECHHHHHHHCCCEEEEEE
LKYVSVNVPERNQLRRSWNQPVFWPLGVLFGLLIALVIPLLITYLKKEKQPAERVKLK
EEEEEECCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; oligopeptides [Periplasm]; H2O [C]

Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1339409; 7542800; 2041470 [H]