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The map label for this gene is dsbD/lidC [H]

Identifier: 54293669

GI number: 54293669

Start: 809889

End: 811649

Strand: Reverse

Name: dsbD/lidC [H]

Synonym: lpl0722

Alternate gene names: 54293669

Gene position: 811649-809889 (Counterclockwise)

Preceding gene: 54293674

Following gene: 54293668

Centisome position: 24.26

GC content: 41.91

Gene sequence:

>1761_bases
ATGAAAAAATGGCTCTTATTTTCCCTATTATTTTTAACTTCCCTTTGTGTTCATGCTGAGCCCTTGCCAGCTTCTGAAGT
ATTTAAGGTTAGTGTAAAAAAAATAGACCCCAATACCTTTGCCATACAATGGAATATCTTGCCCAAGTATTTTTTATATA
GCGACCGTATTCAATTAAATTCCGATAATGATGACATTGCACAGCTTGGAGCTCTTCGCCTCCCCACCCCCTTAACCAAA
ACGGATAAACAAGGGCGAACCTTTAAAGTTTATCGCAATCAGCTTAACCTTCCAGTGGGAGTCCTGGGCATTACCCCAGG
AGAAACAATAGTCAATTTGCGTTTTCAAGGATGTGCCGACGATGGTTTTTGTTATCCCCCCGAAGTAAAACAAATCAAAC
TGGCAATTGACGATAAACTGGCTCTTTCCCAAGTTGATTTGGAAACATTTCATGCACCTGAAGCAACACCTCTTGAAAAA
CCGCAACAAGACATCGCTGATATTTTTGCAAATCATAATTGGATAATGATTCTGCTTATATTTTACGGGTTTGGCCTGCT
CCTGTCCTTTACTCCTTGTATACTTCCCATGGTTCCTGTCCTTTCAGGCATTATTGTTGGTCATGGGAAAACTGCAACCA
CGAAAAAAGCATTTTTCCTGTCATTAAGCTACGTGCTCAGCATGTCTGTCACTTATGCCGTTGTGGGTGCTGTCGTTGCC
CTGCTTGGAGCCAATCTACAAATCAGTATGCAGTCACCATGGGCTATCAGTCTATTCAGTCTGATATTCGTTTTGCTAGC
CTTGTCCATGTTTGGCTTTTATGAATTCAAACTCCCTGATGCGTGGCAAAGCAAAATAGTGGGTTCAAGTCGTGAACAAC
GAGGCGGGCACTATCTTGGTGCAGCCATCATGGGATGTTTGTCCACTCTCATTCTATCACCATGCGTCACAGCACCATTA
ATCGGGGTTTTAACTTACATAGCACAAACCGGAAATGTATTACTCGGCAGTGTCACTCTATTTACCTTAAGTCTCGGCAT
GGGCACTCCATTGCTTCTGATAGGAACGTCTGCCGGTAAATGGCTACCTGAAACAGGAAGCTGGATGAATGCTGTTAAAG
CTTTTTTTGGCATATTACTTCTTGCTGTTGCTATTTATCTGATGGCACGCATTTTACCAGCAGGTTTGGTCATGGGGCTA
TGGGCTTGTCTCCTGATCTTTTCCGGCATTTACTCTGGTGCTTTAACCAAATCGAATACCAACCAGGAAAAGCTCTGCCA
AGGCATTGGTATCATTTTATTAACCTATGGATTGCTGATTCTCATTGGAGCTAGCATGGGCTCTTCCAACCCTTTGCAGC
CTTTAGCCAACTTACAAGCAGCCCCTATTGTAAGCAATGCTTTTGAATCGGCTAAAGCCCAATCTGTTAAAAGTGTTGAA
CTGGCTATAAAACAAGCGTTCGGAAAACCAGTGATGCTTGATTTTTATGCTGACTGGTGTGCATCGTGTAAAGTAATGGA
AAACACCACGTTCAAAGATCCTCGTGTACAAAAAGCTTTGAGCCATTTTATCGTTATCAAAGTGGATGTGACTGCCAATA
ATAAAAATGACAGAGCATTAATGCAGCATTTCCGTGTAGTAGCCCCCCCGACTTTTATCTTTTTTAATGCTCAAGGCATA
CAACTCAATAATTTGAAAAGAGTTGGTGAGCTTAACGCCGATGAATTCATGCAAACAATAAAAAACATTGATGCGAACTA
A

Upstream 100 bases:

>100_bases
GGACAATAAACAAACTTTCAAGGGTAAAATCAAAAAAAATTTTGGATTTGGGATTACAGAGTCTACAATAATGTTTATTA
GTAACAGTAAAAGATATCGA

Downstream 100 bases:

>100_bases
AGTAACTATGGGCACTTTTGTATGAAATCAGTCGACACTGGAACGATTAAGCAGTATAATTAGCTCATTTTTTTTACAGA
TAGAAGTTTATGAATCATAA

Product: hypothetical protein

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 586; Mature: 586

Protein sequence:

>586_residues
MKKWLLFSLLFLTSLCVHAEPLPASEVFKVSVKKIDPNTFAIQWNILPKYFLYSDRIQLNSDNDDIAQLGALRLPTPLTK
TDKQGRTFKVYRNQLNLPVGVLGITPGETIVNLRFQGCADDGFCYPPEVKQIKLAIDDKLALSQVDLETFHAPEATPLEK
PQQDIADIFANHNWIMILLIFYGFGLLLSFTPCILPMVPVLSGIIVGHGKTATTKKAFFLSLSYVLSMSVTYAVVGAVVA
LLGANLQISMQSPWAISLFSLIFVLLALSMFGFYEFKLPDAWQSKIVGSSREQRGGHYLGAAIMGCLSTLILSPCVTAPL
IGVLTYIAQTGNVLLGSVTLFTLSLGMGTPLLLIGTSAGKWLPETGSWMNAVKAFFGILLLAVAIYLMARILPAGLVMGL
WACLLIFSGIYSGALTKSNTNQEKLCQGIGIILLTYGLLILIGASMGSSNPLQPLANLQAAPIVSNAFESAKAQSVKSVE
LAIKQAFGKPVMLDFYADWCASCKVMENTTFKDPRVQKALSHFIVIKVDVTANNKNDRALMQHFRVVAPPTFIFFNAQGI
QLNNLKRVGELNADEFMQTIKNIDAN

Sequences:

>Translated_586_residues
MKKWLLFSLLFLTSLCVHAEPLPASEVFKVSVKKIDPNTFAIQWNILPKYFLYSDRIQLNSDNDDIAQLGALRLPTPLTK
TDKQGRTFKVYRNQLNLPVGVLGITPGETIVNLRFQGCADDGFCYPPEVKQIKLAIDDKLALSQVDLETFHAPEATPLEK
PQQDIADIFANHNWIMILLIFYGFGLLLSFTPCILPMVPVLSGIIVGHGKTATTKKAFFLSLSYVLSMSVTYAVVGAVVA
LLGANLQISMQSPWAISLFSLIFVLLALSMFGFYEFKLPDAWQSKIVGSSREQRGGHYLGAAIMGCLSTLILSPCVTAPL
IGVLTYIAQTGNVLLGSVTLFTLSLGMGTPLLLIGTSAGKWLPETGSWMNAVKAFFGILLLAVAIYLMARILPAGLVMGL
WACLLIFSGIYSGALTKSNTNQEKLCQGIGIILLTYGLLILIGASMGSSNPLQPLANLQAAPIVSNAFESAKAQSVKSVE
LAIKQAFGKPVMLDFYADWCASCKVMENTTFKDPRVQKALSHFIVIKVDVTANNKNDRALMQHFRVVAPPTFIFFNAQGI
QLNNLKRVGELNADEFMQTIKNIDAN
>Mature_586_residues
MKKWLLFSLLFLTSLCVHAEPLPASEVFKVSVKKIDPNTFAIQWNILPKYFLYSDRIQLNSDNDDIAQLGALRLPTPLTK
TDKQGRTFKVYRNQLNLPVGVLGITPGETIVNLRFQGCADDGFCYPPEVKQIKLAIDDKLALSQVDLETFHAPEATPLEK
PQQDIADIFANHNWIMILLIFYGFGLLLSFTPCILPMVPVLSGIIVGHGKTATTKKAFFLSLSYVLSMSVTYAVVGAVVA
LLGANLQISMQSPWAISLFSLIFVLLALSMFGFYEFKLPDAWQSKIVGSSREQRGGHYLGAAIMGCLSTLILSPCVTAPL
IGVLTYIAQTGNVLLGSVTLFTLSLGMGTPLLLIGTSAGKWLPETGSWMNAVKAFFGILLLAVAIYLMARILPAGLVMGL
WACLLIFSGIYSGALTKSNTNQEKLCQGIGIILLTYGLLILIGASMGSSNPLQPLANLQAAPIVSNAFESAKAQSVKSVE
LAIKQAFGKPVMLDFYADWCASCKVMENTTFKDPRVQKALSHFIVIKVDVTANNKNDRALMQHFRVVAPPTFIFFNAQGI
QLNNLKRVGELNADEFMQTIKNIDAN

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=562, Percent_Identity=33.9857651245552, Blast_Score=339, Evalue=3e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 63989; Mature: 63989

Theoretical pI: Translated: 8.77; Mature: 8.77

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKWLLFSLLFLTSLCVHAEPLPASEVFKVSVKKIDPNTFAIQWNILPKYFLYSDRIQLN
CCHHHHHHHHHHHHHHHCCCCCCHHHHHEEEEEEECCCEEEEEEECCCCCCEEECEEEEC
SDNDDIAQLGALRLPTPLTKTDKQGRTFKVYRNQLNLPVGVLGITPGETIVNLRFQGCAD
CCCCHHHHHCCCCCCCCCCCCCCCCCEEEEEHHCCCCCEEEEEECCCCEEEEEEEECCCC
DGFCYPPEVKQIKLAIDDKLALSQVDLETFHAPEATPLEKPQQDIADIFANHNWIMILLI
CCCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCHHHHHHH
FYGFGLLLSFTPCILPMVPVLSGIIVGHGKTATTKKAFFLSLSYVLSMSVTYAVVGAVVA
HHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGANLQISMQSPWAISLFSLIFVLLALSMFGFYEFKLPDAWQSKIVGSSREQRGGHYLG
HHCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHCCCCCHHCCCCHHH
AAIMGCLSTLILSPCVTAPLIGVLTYIAQTGNVLLGSVTLFTLSLGMGTPLLLIGTSAGK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHCCCCCEEEEECCCCC
WLPETGSWMNAVKAFFGILLLAVAIYLMARILPAGLVMGLWACLLIFSGIYSGALTKSNT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
NQEKLCQGIGIILLTYGLLILIGASMGSSNPLQPLANLQAAPIVSNAFESAKAQSVKSVE
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHH
LAIKQAFGKPVMLDFYADWCASCKVMENTTFKDPRVQKALSHFIVIKVDVTANNKNDRAL
HHHHHHCCCCEEEHHHHHHHHCCEEECCCCCCCHHHHHHHCCEEEEEEEEEECCCCHHHH
MQHFRVVAPPTFIFFNAQGIQLNNLKRVGELNADEFMQTIKNIDAN
HHHHHHHCCCEEEEEECCCCEECCHHHHCCCCHHHHHHHHHCCCCC
>Mature Secondary Structure
MKKWLLFSLLFLTSLCVHAEPLPASEVFKVSVKKIDPNTFAIQWNILPKYFLYSDRIQLN
CCHHHHHHHHHHHHHHHCCCCCCHHHHHEEEEEEECCCEEEEEEECCCCCCEEECEEEEC
SDNDDIAQLGALRLPTPLTKTDKQGRTFKVYRNQLNLPVGVLGITPGETIVNLRFQGCAD
CCCCHHHHHCCCCCCCCCCCCCCCCCEEEEEHHCCCCCEEEEEECCCCEEEEEEEECCCC
DGFCYPPEVKQIKLAIDDKLALSQVDLETFHAPEATPLEKPQQDIADIFANHNWIMILLI
CCCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCHHHHHHH
FYGFGLLLSFTPCILPMVPVLSGIIVGHGKTATTKKAFFLSLSYVLSMSVTYAVVGAVVA
HHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGANLQISMQSPWAISLFSLIFVLLALSMFGFYEFKLPDAWQSKIVGSSREQRGGHYLG
HHCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHCCCCCHHCCCCHHH
AAIMGCLSTLILSPCVTAPLIGVLTYIAQTGNVLLGSVTLFTLSLGMGTPLLLIGTSAGK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHCCCCCEEEEECCCCC
WLPETGSWMNAVKAFFGILLLAVAIYLMARILPAGLVMGLWACLLIFSGIYSGALTKSNT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
NQEKLCQGIGIILLTYGLLILIGASMGSSNPLQPLANLQAAPIVSNAFESAKAQSVKSVE
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHH
LAIKQAFGKPVMLDFYADWCASCKVMENTTFKDPRVQKALSHFIVIKVDVTANNKNDRAL
HHHHHHCCCCEEEHHHHHHHHCCEEECCCCCCCHHHHHHHCCEEEEEEEEEECCCCHHHH
MQHFRVVAPPTFIFFNAQGIQLNNLKRVGELNADEFMQTIKNIDAN
HHHHHHHCCCEEEEEECCCCEECCHHHHCCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA