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The map label for this gene is rlmM [H]

Identifier: 54293591

GI number: 54293591

Start: 693657

End: 694571

Strand: Reverse

Name: rlmM [H]

Synonym: lpl0643

Alternate gene names: 54293591

Gene position: 694571-693657 (Counterclockwise)

Preceding gene: 54293592

Following gene: 54293582

Centisome position: 20.76

GC content: 39.89

Gene sequence:

>915_bases
ATGGAACTGCCCAATCATTTCTCTACTGTCTATGTGTCAAAACCAGAATTTATAGAAACACTTTCTGATGAGTTAGGCGA
GGTATCCAATAAAATAGGCTCTCTCGTTTTTTCTCCTCATCAGAAGCTTGATGTTTGTTTTGCACTGGATGTATGGATTG
AACCTGAGATAGTAACCTTTCAATCGATTTCAGAAGCAGCAAAAATATTGAGGCAAGCCGGAAAATTCTGGTATTTGCAC
CCTGTTACTGAAATTCGCCGATCGCGCTTGATTGAGGAACAACTTCGCAAGTGTCCATCACTAACGTCCCATTTTCCAGT
TACAAATGACATTCCGCCCATAGGTGTATTTAGTCTTCTTGATAGAAACACTCTACTCTTTAGCGCCAAACGACTAAAAA
AATGGCCGGATGGACAATGTTATTTTATTGAAGACAAAGCCAATCCCCCAAATCGGGCTTATTTAAAATTATGGGAAGCC
TTGTTTTTGTTAAATAAATACCCTCGCCCCGGTGAAACAGTTTTAGATTTGGGAGCATCCCCGGGAGGTTGGACATATGT
GATGCAATCAGTCGGAACCCAAGTCACTTCGGTCGACAAAGCAGAACTGGATACAAAAATCATGGCGCTTCCCAGAGTCA
GTTTTTTAAAACAAAGCGCCTTTGCCCTAGATCCCGAACAACTTACAGAGTCTTATGACTGGGTACTTTCCGATGTTGCC
TGCTATCCTGACAGAGCCTACACCCTCATCAAAAAATGGATAGCATCAAAAAAAGCAAGACAGTTGATTTTTACCATCAA
ACTACAGGGACAAACTGACTTAAACACAATCAAACGATTTCAATCCATACCTAATTCTAAAGTAATCAATCTGTTTTATA
ACAAACATGAAGTCACGTTTTTTTATCCAGTATAA

Upstream 100 bases:

>100_bases
GTCAAACGCTAATCGAGACAAAAATATAGAAAAAGAATACAAAATCGCCTAAATTACAGCATTTGACTTTGTCGCCATTA
ACCTGCGAGCGTTATTTATC

Downstream 100 bases:

>100_bases
ACATAACCAGGATTTAGTGATTATGTCTGCAAAAATATCATAATGACAAGCTAATACTTAATTTTCTATGACTTAAGACC
TTGAAAAATCAAATGAGAGA

Product: hypothetical protein

Products: NA

Alternate protein names: 23S rRNA 2'-O-ribose methyltransferase rlmM [H]

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MELPNHFSTVYVSKPEFIETLSDELGEVSNKIGSLVFSPHQKLDVCFALDVWIEPEIVTFQSISEAAKILRQAGKFWYLH
PVTEIRRSRLIEEQLRKCPSLTSHFPVTNDIPPIGVFSLLDRNTLLFSAKRLKKWPDGQCYFIEDKANPPNRAYLKLWEA
LFLLNKYPRPGETVLDLGASPGGWTYVMQSVGTQVTSVDKAELDTKIMALPRVSFLKQSAFALDPEQLTESYDWVLSDVA
CYPDRAYTLIKKWIASKKARQLIFTIKLQGQTDLNTIKRFQSIPNSKVINLFYNKHEVTFFYPV

Sequences:

>Translated_304_residues
MELPNHFSTVYVSKPEFIETLSDELGEVSNKIGSLVFSPHQKLDVCFALDVWIEPEIVTFQSISEAAKILRQAGKFWYLH
PVTEIRRSRLIEEQLRKCPSLTSHFPVTNDIPPIGVFSLLDRNTLLFSAKRLKKWPDGQCYFIEDKANPPNRAYLKLWEA
LFLLNKYPRPGETVLDLGASPGGWTYVMQSVGTQVTSVDKAELDTKIMALPRVSFLKQSAFALDPEQLTESYDWVLSDVA
CYPDRAYTLIKKWIASKKARQLIFTIKLQGQTDLNTIKRFQSIPNSKVINLFYNKHEVTFFYPV
>Mature_304_residues
MELPNHFSTVYVSKPEFIETLSDELGEVSNKIGSLVFSPHQKLDVCFALDVWIEPEIVTFQSISEAAKILRQAGKFWYLH
PVTEIRRSRLIEEQLRKCPSLTSHFPVTNDIPPIGVFSLLDRNTLLFSAKRLKKWPDGQCYFIEDKANPPNRAYLKLWEA
LFLLNKYPRPGETVLDLGASPGGWTYVMQSVGTQVTSVDKAELDTKIMALPRVSFLKQSAFALDPEQLTESYDWVLSDVA
CYPDRAYTLIKKWIASKKARQLIFTIKLQGQTDLNTIKRFQSIPNSKVINLFYNKHEVTFFYPV

Specific function: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA [H]

COG id: COG2933

COG function: function code R; Predicted SAM-dependent methyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RlmE family. RlmM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789171, Length=128, Percent_Identity=29.6875, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011224
- InterPro:   IPR002877 [H]

Pfam domain/function: PF01728 FtsJ [H]

EC number: NA

Molecular weight: Translated: 34888; Mature: 34888

Theoretical pI: Translated: 8.56; Mature: 8.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELPNHFSTVYVSKPEFIETLSDELGEVSNKIGSLVFSPHQKLDVCFALDVWIEPEIVTF
CCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCEEEH
QSISEAAKILRQAGKFWYLHPVTEIRRSRLIEEQLRKCPSLTSHFPVTNDIPPIGVFSLL
HHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHH
DRNTLLFSAKRLKKWPDGQCYFIEDKANPPNRAYLKLWEALFLLNKYPRPGETVLDLGAS
CCCHHEEEHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCHHEECCCC
PGGWTYVMQSVGTQVTSVDKAELDTKIMALPRVSFLKQSAFALDPEQLTESYDWVLSDVA
CCHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
CYPDRAYTLIKKWIASKKARQLIFTIKLQGQTDLNTIKRFQSIPNSKVINLFYNKHEVTF
HCCHHHHHHHHHHHHHHHHCEEEEEEEECCCCCHHHHHHHHHCCCCEEEEEEECCEEEEE
FYPV
EECC
>Mature Secondary Structure
MELPNHFSTVYVSKPEFIETLSDELGEVSNKIGSLVFSPHQKLDVCFALDVWIEPEIVTF
CCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCEEEH
QSISEAAKILRQAGKFWYLHPVTEIRRSRLIEEQLRKCPSLTSHFPVTNDIPPIGVFSLL
HHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHH
DRNTLLFSAKRLKKWPDGQCYFIEDKANPPNRAYLKLWEALFLLNKYPRPGETVLDLGAS
CCCHHEEEHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCHHEECCCC
PGGWTYVMQSVGTQVTSVDKAELDTKIMALPRVSFLKQSAFALDPEQLTESYDWVLSDVA
CCHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
CYPDRAYTLIKKWIASKKARQLIFTIKLQGQTDLNTIKRFQSIPNSKVINLFYNKHEVTF
HCCHHHHHHHHHHHHHHHHCEEEEEEEECCCCCHHHHHHHHHCCCCEEEEEEECCEEEEE
FYPV
EECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA