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The map label for this gene is yciR [C]

Identifier: 54293281

GI number: 54293281

Start: 377768

End: 379990

Strand: Reverse

Name: yciR [C]

Synonym: lpl0329

Alternate gene names: 54293281

Gene position: 379990-377768 (Counterclockwise)

Preceding gene: 54293282

Following gene: 54293277

Centisome position: 11.36

GC content: 39.36

Gene sequence:

>2223_bases
ATGAGTACTGAATCTTTTCACATTCTGGTCATTGATGACAACCCGGCAATCCATCAGGATTTTATGAAAATCTTAAATGT
CAGCAAGAACTCTGCATTACTAAATAAATTTGATGCCGAGCTGTTTGGTGATGAGACAGAGCAGCTTGGAATTTCTTTGC
CTGAATTTAAAATCGATGTAGCGACTCAAGGCATTGAAGGCATAGAAAAAGTGAAACGCTCACTTGAAGAAGGCCGGCCA
TACCCACTCGCCTTTGTTGACATAAGAATGCCCCCGGGGATAGATGGGATAGAAACCATCAAACGCATTTGGGCCATTGA
CCCACAAATACAAATTGTTATATGCAGTGCCTATTCCGACTACTCATGGGAAAGCACAGTGAATACCTTGGGTTTAAGTG
ATAATTTATTGGTGCTAAAAAAGCCCTTTGATGTGATTGCGGTAAGACAGCTGGCAAGTGCTTTGACACAAAAATGGGTA
CTTGCCAGAGAAACTCAAAAACACACTGAATTTTTAAATCAATTGGTAGAGGAAAGAACCGAATCTTTGCAACAATCCTT
CTCCTTATTGAGAGCAACGATTGAGTCCTCTTCGGATGGCATTCTGGTTGTCGATTTACAAGGAAAAATCGTTGATTACA
ACTCTCAATTCGTCAAATTGTGGAATATACCCGAATCCATCATGAAAAAAACCAGCGAATCCCAACTCATTCAGTATATG
TCAACGCAATTACTCAATTCAGAACAACATGCCCAACATGTTAAAGAATTTTCTATTCACATCGATGATTCCAGTATACA
AATTTATCATTTTAGAAATGGTAAAGTGGTTGAATGCTGTTCCAAACCGCATCGCGTTGGTCCGCAAACGGTAGGCCGTG
TATGGAGCTTCAGAGACATCACTGAGCAAACGCGATTAAAGGAAAAACTGGAGTATCAGGCTACTCATGACGCATTAACC
AATTTACCCAATCGCTTGTTATTAATTGATCGTATTGAACATGCTATCAGCAGCTATGCCCGCCATAAAATGAAATTTGC
CATATTATTTTTTGACTTGGACCGCTTTAAAATGATCAATGACAGCTTGAGCCATGAAGCAGGCGATCAATTACTGTGTG
CTGTTGCTAAACGATTACGATCTTTGGTGCGAAAAGAAGATACTCTCGCCAGACTTGGTGGGGATGAGTTTGTAATGCTT
TTTCAATCGTTTAATTCTGAAGAGCAAATTGCCGGAGTAGCTCAAAAAATCCTCAAATCCTTTCAAAAACCATTTCATAT
TGCTGAAAGAGACATCAATATTCATGTCAGCATAGGTATTAGCGTTTATCCAACGGATGGCAAAACAGTAAACACTTTAC
TCAGTAATGCGGATATGGCTATGTATCAGGCAAAATTTCGCGGCGGTAACCAATTCTCATTTTATACAGAGAAACTCAAC
AAAAAAACAAACCAGCAATTTCAGCTGGAATTGGACTTGCAAAAAGCGATTATCCATCATGAGTTTTTCCTCCTTTACCA
GCCTCAATTTACAGTTAATACTCATGAGATTCGTTCCATGGAAGCATTAATCCGGTGGAATCACCCGCAAAAAGGTATTA
TTTTACCTTTGGATTTTATTCCCACTGCCGAAAGTTCAGGGCTTATCGTACCGATAGGGGAGTGGGTTTTGCGGGAAACC
TGTAAACAAATTGGTACGTGGCGCACAATGGGGCTGCCTGAAATTCGTGTCGCTTGTAATGTAGCAAGTAAACAGTTAAG
ACAACGAGATTTCCCGGCAATGGTGAAGGATCTTTTAAAAGAATATTCAGTCGAACCTCATTGTCTGGAGCTGGAAATTA
CTGAAAATGTGATTATTGACAAAGAAATACAAAGAACGATCAAAAAGTTGAAATCACTGGGTGTGTTGATTATTTTAGAT
GATTTTGGCACAGGAAATTCCAGCCTGAATTTATTAAAACAGGTCGCTGTCGATAGTCTTAAAATCGACCAATCATTCAT
TCAGAATATTTCAAAATCGCCAGGAGATGAAGCGATCATTGATGCGATTATTGCTATCGCACAAAGCATGAATTTTAATA
TCATCGCCGAAGGAGTCGAAACGCAAAACCAGCTTAAATTCCTCAAGAAAAGGCGATGTAATGACATTCAGGGCTTTTTA
ATGAGCAAGCCTATACCACCAGAAGAGATAGAAAAACTTCTGCAAGGAAATAGGACAAAATAA

Upstream 100 bases:

>100_bases
TGGGTGGTACACTTTATGCTGAAAGTAATGGCAATGGCAAAGGAGCTCAATTTGTATTAGATTTGCCCATCAATCCCAAA
ACCTTGAGTACGAGGTAGAA

Downstream 100 bases:

>100_bases
GATAAAAATCGGATTGGCATCTACAAGAGCTATCCGATGGATTGCAATTATAGATGCAAGACAAATTACACCGTAATCAT
AACGGTTTGATCACGTAAAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 740; Mature: 739

Protein sequence:

>740_residues
MSTESFHILVIDDNPAIHQDFMKILNVSKNSALLNKFDAELFGDETEQLGISLPEFKIDVATQGIEGIEKVKRSLEEGRP
YPLAFVDIRMPPGIDGIETIKRIWAIDPQIQIVICSAYSDYSWESTVNTLGLSDNLLVLKKPFDVIAVRQLASALTQKWV
LARETQKHTEFLNQLVEERTESLQQSFSLLRATIESSSDGILVVDLQGKIVDYNSQFVKLWNIPESIMKKTSESQLIQYM
STQLLNSEQHAQHVKEFSIHIDDSSIQIYHFRNGKVVECCSKPHRVGPQTVGRVWSFRDITEQTRLKEKLEYQATHDALT
NLPNRLLLIDRIEHAISSYARHKMKFAILFFDLDRFKMINDSLSHEAGDQLLCAVAKRLRSLVRKEDTLARLGGDEFVML
FQSFNSEEQIAGVAQKILKSFQKPFHIAERDINIHVSIGISVYPTDGKTVNTLLSNADMAMYQAKFRGGNQFSFYTEKLN
KKTNQQFQLELDLQKAIIHHEFFLLYQPQFTVNTHEIRSMEALIRWNHPQKGIILPLDFIPTAESSGLIVPIGEWVLRET
CKQIGTWRTMGLPEIRVACNVASKQLRQRDFPAMVKDLLKEYSVEPHCLELEITENVIIDKEIQRTIKKLKSLGVLIILD
DFGTGNSSLNLLKQVAVDSLKIDQSFIQNISKSPGDEAIIDAIIAIAQSMNFNIIAEGVETQNQLKFLKKRRCNDIQGFL
MSKPIPPEEIEKLLQGNRTK

Sequences:

>Translated_740_residues
MSTESFHILVIDDNPAIHQDFMKILNVSKNSALLNKFDAELFGDETEQLGISLPEFKIDVATQGIEGIEKVKRSLEEGRP
YPLAFVDIRMPPGIDGIETIKRIWAIDPQIQIVICSAYSDYSWESTVNTLGLSDNLLVLKKPFDVIAVRQLASALTQKWV
LARETQKHTEFLNQLVEERTESLQQSFSLLRATIESSSDGILVVDLQGKIVDYNSQFVKLWNIPESIMKKTSESQLIQYM
STQLLNSEQHAQHVKEFSIHIDDSSIQIYHFRNGKVVECCSKPHRVGPQTVGRVWSFRDITEQTRLKEKLEYQATHDALT
NLPNRLLLIDRIEHAISSYARHKMKFAILFFDLDRFKMINDSLSHEAGDQLLCAVAKRLRSLVRKEDTLARLGGDEFVML
FQSFNSEEQIAGVAQKILKSFQKPFHIAERDINIHVSIGISVYPTDGKTVNTLLSNADMAMYQAKFRGGNQFSFYTEKLN
KKTNQQFQLELDLQKAIIHHEFFLLYQPQFTVNTHEIRSMEALIRWNHPQKGIILPLDFIPTAESSGLIVPIGEWVLRET
CKQIGTWRTMGLPEIRVACNVASKQLRQRDFPAMVKDLLKEYSVEPHCLELEITENVIIDKEIQRTIKKLKSLGVLIILD
DFGTGNSSLNLLKQVAVDSLKIDQSFIQNISKSPGDEAIIDAIIAIAQSMNFNIIAEGVETQNQLKFLKKRRCNDIQGFL
MSKPIPPEEIEKLLQGNRTK
>Mature_739_residues
STESFHILVIDDNPAIHQDFMKILNVSKNSALLNKFDAELFGDETEQLGISLPEFKIDVATQGIEGIEKVKRSLEEGRPY
PLAFVDIRMPPGIDGIETIKRIWAIDPQIQIVICSAYSDYSWESTVNTLGLSDNLLVLKKPFDVIAVRQLASALTQKWVL
ARETQKHTEFLNQLVEERTESLQQSFSLLRATIESSSDGILVVDLQGKIVDYNSQFVKLWNIPESIMKKTSESQLIQYMS
TQLLNSEQHAQHVKEFSIHIDDSSIQIYHFRNGKVVECCSKPHRVGPQTVGRVWSFRDITEQTRLKEKLEYQATHDALTN
LPNRLLLIDRIEHAISSYARHKMKFAILFFDLDRFKMINDSLSHEAGDQLLCAVAKRLRSLVRKEDTLARLGGDEFVMLF
QSFNSEEQIAGVAQKILKSFQKPFHIAERDINIHVSIGISVYPTDGKTVNTLLSNADMAMYQAKFRGGNQFSFYTEKLNK
KTNQQFQLELDLQKAIIHHEFFLLYQPQFTVNTHEIRSMEALIRWNHPQKGIILPLDFIPTAESSGLIVPIGEWVLRETC
KQIGTWRTMGLPEIRVACNVASKQLRQRDFPAMVKDLLKEYSVEPHCLELEITENVIIDKEIQRTIKKLKSLGVLIILDD
FGTGNSSLNLLKQVAVDSLKIDQSFIQNISKSPGDEAIIDAIIAIAQSMNFNIIAEGVETQNQLKFLKKRRCNDIQGFLM
SKPIPPEEIEKLLQGNRTK

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=468, Percent_Identity=37.8205128205128, Blast_Score=327, Evalue=2e-90,
Organism=Escherichia coli, GI87081921, Length=435, Percent_Identity=33.5632183908046, Blast_Score=248, Evalue=9e-67,
Organism=Escherichia coli, GI226510982, Length=419, Percent_Identity=29.8329355608592, Blast_Score=202, Evalue=9e-53,
Organism=Escherichia coli, GI87081980, Length=268, Percent_Identity=35.0746268656716, Blast_Score=152, Evalue=7e-38,
Organism=Escherichia coli, GI1790496, Length=237, Percent_Identity=32.4894514767932, Blast_Score=141, Evalue=2e-34,
Organism=Escherichia coli, GI1788502, Length=249, Percent_Identity=31.7269076305221, Blast_Score=140, Evalue=3e-34,
Organism=Escherichia coli, GI87081845, Length=259, Percent_Identity=30.8880308880309, Blast_Score=133, Evalue=3e-32,
Organism=Escherichia coli, GI1788381, Length=539, Percent_Identity=25.7884972170686, Blast_Score=132, Evalue=8e-32,
Organism=Escherichia coli, GI1786507, Length=233, Percent_Identity=33.4763948497854, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI87081743, Length=238, Percent_Identity=32.7731092436975, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI1787055, Length=301, Percent_Identity=29.9003322259136, Blast_Score=127, Evalue=3e-30,
Organism=Escherichia coli, GI1788849, Length=239, Percent_Identity=35.1464435146443, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI87081881, Length=177, Percent_Identity=36.1581920903955, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI87081977, Length=156, Percent_Identity=35.8974358974359, Blast_Score=92, Evalue=2e-19,
Organism=Escherichia coli, GI87082096, Length=432, Percent_Identity=22.9166666666667, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI87082007, Length=177, Percent_Identity=35.0282485875706, Blast_Score=87, Evalue=5e-18,
Organism=Escherichia coli, GI1787816, Length=171, Percent_Identity=32.7485380116959, Blast_Score=86, Evalue=9e-18,
Organism=Escherichia coli, GI1786584, Length=178, Percent_Identity=26.4044943820225, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1788085, Length=216, Percent_Identity=29.1666666666667, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1788956, Length=167, Percent_Identity=34.1317365269461, Blast_Score=80, Evalue=7e-16,
Organism=Escherichia coli, GI145693134, Length=182, Percent_Identity=31.8681318681319, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1787802, Length=173, Percent_Identity=29.4797687861272, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1787262, Length=164, Percent_Identity=29.8780487804878, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1789650, Length=440, Percent_Identity=20.2272727272727, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1787410, Length=127, Percent_Identity=33.8582677165354, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI87081974, Length=125, Percent_Identity=32.8, Blast_Score=67, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 84397; Mature: 84266

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: PS50112 PAS ; PS50110 RESPONSE_REGULATORY ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTESFHILVIDDNPAIHQDFMKILNVSKNSALLNKFDAELFGDETEQLGISLPEFKIDV
CCCCCEEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHCCCCCCEEEEH
ATQGIEGIEKVKRSLEEGRPYPLAFVDIRMPPGIDGIETIKRIWAIDPQIQIVICSAYSD
HHCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCCEEEEEEECCCC
YSWESTVNTLGLSDNLLVLKKPFDVIAVRQLASALTQKWVLARETQKHTEFLNQLVEERT
CCCHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESLQQSFSLLRATIESSSDGILVVDLQGKIVDYNSQFVKLWNIPESIMKKTSESQLIQYM
HHHHHHHHHHHHHHCCCCCCEEEEEECCCEEECCCCEEEEECCCHHHHHCCCHHHHHHHH
STQLLNSEQHAQHVKEFSIHIDDSSIQIYHFRNGKVVECCSKPHRVGPQTVGRVWSFRDI
HHHHHCCHHHHHHHHHHEEEEECCEEEEEEECCCCEEEECCCCCCCCHHHHHHHHHHHHH
TEQTRLKEKLEYQATHDALTNLPNRLLLIDRIEHAISSYARHKMKFAILFFDLDRFKMIN
HHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHEEEEEEEECHHHHHHH
DSLSHEAGDQLLCAVAKRLRSLVRKEDTLARLGGDEFVMLFQSFNSEEQIAGVAQKILKS
HHHCHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHCCCHHHHHHHHHHHHHH
FQKPFHIAERDINIHVSIGISVYPTDGKTVNTLLSNADMAMYQAKFRGGNQFSFYTEKLN
HCCCCEEECCCEEEEEEEEEEEECCCCCHHHHHHCCCHHHHHHHHHCCCCEEHHHHHHHC
KKTNQQFQLELDLQKAIIHHEFFLLYQPQFTVNTHEIRSMEALIRWNHPQKGIILPLDFI
CCCCCEEEEEEHHHHHHHHHHEEEEECCCEECCHHHHHHHHHHHHCCCCCCCEEEEEECC
PTAESSGLIVPIGEWVLRETCKQIGTWRTMGLPEIRVACNVASKQLRQRDFPAMVKDLLK
CCCCCCCEEEEHHHHHHHHHHHHHCCEECCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHH
EYSVEPHCLELEITENVIIDKEIQRTIKKLKSLGVLIILDDFGTGNSSLNLLKQVAVDSL
HCCCCCCEEEEEECCCEEECHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHH
KIDQSFIQNISKSPGDEAIIDAIIAIAQSMNFNIIAEGVETQNQLKFLKKRRCNDIQGFL
HCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHCCCHHHHHH
MSKPIPPEEIEKLLQGNRTK
HCCCCCHHHHHHHHCCCCCC
>Mature Secondary Structure 
STESFHILVIDDNPAIHQDFMKILNVSKNSALLNKFDAELFGDETEQLGISLPEFKIDV
CCCCEEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHCCCCCCEEEEH
ATQGIEGIEKVKRSLEEGRPYPLAFVDIRMPPGIDGIETIKRIWAIDPQIQIVICSAYSD
HHCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCCEEEEEEECCCC
YSWESTVNTLGLSDNLLVLKKPFDVIAVRQLASALTQKWVLARETQKHTEFLNQLVEERT
CCCHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESLQQSFSLLRATIESSSDGILVVDLQGKIVDYNSQFVKLWNIPESIMKKTSESQLIQYM
HHHHHHHHHHHHHHCCCCCCEEEEEECCCEEECCCCEEEEECCCHHHHHCCCHHHHHHHH
STQLLNSEQHAQHVKEFSIHIDDSSIQIYHFRNGKVVECCSKPHRVGPQTVGRVWSFRDI
HHHHHCCHHHHHHHHHHEEEEECCEEEEEEECCCCEEEECCCCCCCCHHHHHHHHHHHHH
TEQTRLKEKLEYQATHDALTNLPNRLLLIDRIEHAISSYARHKMKFAILFFDLDRFKMIN
HHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHEEEEEEEECHHHHHHH
DSLSHEAGDQLLCAVAKRLRSLVRKEDTLARLGGDEFVMLFQSFNSEEQIAGVAQKILKS
HHHCHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHCCCHHHHHHHHHHHHHH
FQKPFHIAERDINIHVSIGISVYPTDGKTVNTLLSNADMAMYQAKFRGGNQFSFYTEKLN
HCCCCEEECCCEEEEEEEEEEEECCCCCHHHHHHCCCHHHHHHHHHCCCCEEHHHHHHHC
KKTNQQFQLELDLQKAIIHHEFFLLYQPQFTVNTHEIRSMEALIRWNHPQKGIILPLDFI
CCCCCEEEEEEHHHHHHHHHHEEEEECCCEECCHHHHHHHHHHHHCCCCCCCEEEEEECC
PTAESSGLIVPIGEWVLRETCKQIGTWRTMGLPEIRVACNVASKQLRQRDFPAMVKDLLK
CCCCCCCEEEEHHHHHHHHHHHHHCCEECCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHH
EYSVEPHCLELEITENVIIDKEIQRTIKKLKSLGVLIILDDFGTGNSSLNLLKQVAVDSL
HCCCCCCEEEEEECCCEEECHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHH
KIDQSFIQNISKSPGDEAIIDAIIAIAQSMNFNIIAEGVETQNQLKFLKKRRCNDIQGFL
HCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHCCCHHHHHH
MSKPIPPEEIEKLLQGNRTK
HCCCCCHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]